 Repressor Proteins
"Repressor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.
| Descriptor ID |
D012097
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| MeSH Number(s) |
D12.776.260.703 D12.776.930.780
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Repressor Proteins".
Below are MeSH descriptors whose meaning is more specific than "Repressor Proteins".
This graph shows the total number of publications written about "Repressor Proteins" by people in this website by year, and whether "Repressor Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 1 | 2 | 3 | | 1997 | 6 | 0 | 6 | | 1998 | 4 | 1 | 5 | | 1999 | 3 | 3 | 6 | | 2000 | 1 | 5 | 6 | | 2001 | 7 | 4 | 11 | | 2002 | 11 | 3 | 14 | | 2003 | 3 | 0 | 3 | | 2004 | 5 | 4 | 9 | | 2005 | 3 | 5 | 8 | | 2006 | 8 | 1 | 9 | | 2007 | 7 | 6 | 13 | | 2008 | 4 | 7 | 11 | | 2009 | 9 | 0 | 9 | | 2010 | 7 | 12 | 19 | | 2011 | 9 | 8 | 17 | | 2012 | 8 | 10 | 18 | | 2013 | 10 | 11 | 21 | | 2014 | 13 | 8 | 21 | | 2015 | 14 | 3 | 17 | | 2016 | 9 | 3 | 12 | | 2017 | 6 | 10 | 16 | | 2018 | 10 | 7 | 17 | | 2019 | 6 | 2 | 8 | | 2020 | 6 | 2 | 8 | | 2021 | 6 | 3 | 9 | | 2022 | 2 | 9 | 11 | | 2023 | 0 | 5 | 5 | | 2024 | 4 | 4 | 8 | | 2025 | 7 | 1 | 8 | | 2026 | 1 | 1 | 2 |
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Below are the most recent publications written about "Repressor Proteins" by people in Profiles.
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Xia W, Morcom L, Xu Z, Lu IL, Wang Q, Hoi KK, Wei M, Zhu K, Jordan G, Tang XY, Gonzalez-Maya J, Mattera VS, Panigrahi SM, Kawaguchi R, Emery B, Franco SJ, Geschwind DH, Popko B, Rowitch DH, Fancy SPJ. Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair. Nature. 2026 May; 653(8115):819-830.
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Selvam K, Lu S, Messmer C, Pang Y, Biswas S, Khalil M, Zhang P, Tulaiha R, Zhou MM, Kitamura T, Lauberth SM, Blanco MA, Yang FC, Affar EB, Zhao Z, Zeng L, Wang L, Kutateladze TG. Recruitment of BRD4 to the ASXL1 genomic targets depends on the extra-terminal domain of BRD4. Nat Commun. 2026 Feb 17; 17(1).
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Yu Z, Vromman A, Nguyen NQH, Schuermans A, Li L, Rentz T, Nakao T, Vellarikkal SK, Uddin MM, Niroula A, Griffin G, Honigberg MC, Lin AE, Gibson CJ, Katz DH, Tahir UA, Fang S, Dron JS, Pan M, Haidermota S, Ganesh S, Antoine T, Weinstock J, Austin TR, Vasan RS, Peloso GM, Hornsby W, Ganz P, Manson JE, Haring B, Kooperberg C, Reiner AP, Bis JC, Psaty BM, Min YI, Correa A, Lange LA, Post WS, Rotter JI, Rich SS, Wilson JG, Ebert BL, Yu B, Ballantyne CM, Coresh J, Sankaran VG, Bick AG, Jaiswal S, Gerszten RE, Libby P, Gupta RM, Natarajan P. Human plasma proteomic profile of clonal hematopoiesis. Nat Commun. 2025 Nov 27; 16(1):11688.
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Finlay-Schultz J, Vinod Paul K, Erickson B, Fettig LM, Hastings BS, Johnson DL, Bentley DL, Kabos P, Sartorius CA. Maf1 cooperates with progesterone receptor to repress RNA polymerase III transcription of select tRNAs. Nucleic Acids Res. 2025 Oct 28; 53(20).
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Yan H, Wang R, Viswanadhapalli S, Cervantes C, He F, Wu S, Khosh A, Luo W, Wang J, Fernandez MJ, Pratap UP, Khan M, Hinton K, Vankamamidi SE, Perez D, Rivera CE, Gupta HB, Zhang F, Ye Z, Chen Y, Li XD, Sareddy GR, Zan H, Li Y, Wang E, Bunnik EM, Zhong G, Hunter CA, Kedl RM, Yin Z, Min B, Ebrahimi D, Zheng S, Curiel TJ, Xiang Y, Vadlamudi RK, Casali P, Xu Z. Ligand-receptor interactions induce and mediate regulatory functions of BATF3+ B cells. Sci Adv. 2025 Oct 10; 11(41):eadx9917.
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Pawar AS, Somers P, Alex A, Grana J, Feist VK, George SS, Jalnapurkar SS, Antony C, Verner R, White-Brown SK, Khera M, Mendoza-Figueroa MS, Liu KF, Morrissette JJD, Gurbuxani S, Paralkar VR. Leukemia mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness. Genes Dev. 2025 10 01; 39(19-20):1219-1240.
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Crowley SJ, Yang W, White LS, Wu J, Li Y, Schmidt H, Choi K, Magee JA, Bednarski JJ. BCLAF1 restrains stress responses in hematopoietic stem cells to support expansion and repopulation. Blood Adv. 2025 Aug 12; 9(15):4043-4057.
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Darmusey L, Bagley AJ, Nguyen TT, Carlson HL, Blaylock H, Shrestha SB, Pang A, Tauchmann S, Taylor SC, Foley AC, Niño KE, Pietras EM, Braun TP, Maxson JE. Dual ASXL1 and CSF3R mutations drive myeloid-biased stem cell expansion and enhance neutrophil differentiation. Blood Adv. 2025 Apr 08; 9(7):1593-1607.
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Biswas S, Lee JE, Xie G, Masclef L, Ren Z, Côté J, Affar EB, Ge K, Kutateladze TG. Colorectal cancer hot spot mutations attenuate the ASXL-MLL4 interaction. J Biol Chem. 2025 03; 301(3):108333.
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Oguh AU, Haemmerle MW, Sen S, Rozo AV, Shrestha S, Cartailler JP, Fazelinia H, Ding H, Preza S, Yang J, Yang X, Sussel L, Alvarez-Dominguez JR, Doliba N, Spruce LA, Arrojo E Drigo R, Stoffers DA. E3 ligase substrate adaptor SPOP fine-tunes the UPR of pancreatic ß cells. Genes Dev. 2025 02 03; 39(3-4):261-279.
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