 Serotonin
"Serotonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
| Descriptor ID |
D012701
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| MeSH Number(s) |
D02.092.211.215.801.852 D03.633.100.473.914.814 D23.469.050.650
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| Concept/Terms |
Serotonin- Serotonin
- 5-Hydroxytryptamine
- 5 Hydroxytryptamine
- Hippophaine
- 3-(2-Aminoethyl)-1H-indol-5-ol
- Enteramine
- 5-HT
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Below are MeSH descriptors whose meaning is more general than "Serotonin".
Below are MeSH descriptors whose meaning is more specific than "Serotonin".
This graph shows the total number of publications written about "Serotonin" by people in this website by year, and whether "Serotonin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 | | 1995 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 2 | 3 | | 1998 | 2 | 0 | 2 | | 1999 | 2 | 1 | 3 | | 2000 | 3 | 0 | 3 | | 2001 | 2 | 1 | 3 | | 2002 | 0 | 2 | 2 | | 2003 | 7 | 4 | 11 | | 2004 | 5 | 6 | 11 | | 2005 | 12 | 5 | 17 | | 2006 | 5 | 6 | 11 | | 2007 | 5 | 3 | 8 | | 2008 | 4 | 6 | 10 | | 2009 | 4 | 7 | 11 | | 2010 | 5 | 3 | 8 | | 2011 | 5 | 5 | 10 | | 2012 | 3 | 5 | 8 | | 2013 | 5 | 3 | 8 | | 2014 | 5 | 4 | 9 | | 2015 | 6 | 3 | 9 | | 2016 | 2 | 3 | 5 | | 2017 | 6 | 8 | 14 | | 2018 | 1 | 2 | 3 | | 2019 | 2 | 3 | 5 | | 2020 | 2 | 5 | 7 | | 2021 | 1 | 1 | 2 | | 2022 | 1 | 2 | 3 |
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Below are the most recent publications written about "Serotonin" by people in Profiles.
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Andrews PW, Bosyj C, Brenton L, Green L, Gasser PJ, Lowry CA, Pickel VM. All the brain's a stage for serotonin: the forgotten story of serotonin diffusion across cell membranes. Proc Biol Sci. 2022 11 09; 289(1986):20221565.
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Roberts DS, Sherlock LG, Posey JN, Archambault JL, Nozik ES, Delaney CA. Serotonin-deficient neonatal mice are not protected against the development of experimental bronchopulmonary dysplasia or pulmonary hypertension. Physiol Rep. 2022 10; 10(19):e15482.
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Bauer EE, Agbemafle I, Reddy MB, Clark PJ. Edible insects prevent changes to brain monoamine profiles from malnourishment in weaned rats. Nutr Neurosci. 2023 Sep; 26(9):875-887.
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Russo AM, Payet JM, Kent S, Lesku JA, Lowry CA, Hale MW. Acute treatment with 5-hydroxytryptophan increases social approach behaviour but does not activate serotonergic neurons in the dorsal raphe nucleus in juvenile male BALB/c mice: A model of human disorders with deficits of sociability. J Psychopharmacol. 2022 07; 36(7):806-818.
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Reed CH, Bauer EE, Shoeman A, Buhr TJ, Clark PJ. Acute Stress Exposure Alters Food-Related Brain Monoaminergic Profiles in a Rat Model of Anorexia. J Nutr. 2021 12 03; 151(12):3617-3627.
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Chen K, Palagashvili T, Hsu W, Chen Y, Tabakoff B, Hong F, Shih AT, Shih JC. Brain injury and inflammation genes common to a number of neurological diseases and the genes involved in the genesis of GABAnergic neurons are altered in monoamine oxidase B knockout mice. Brain Res. 2022 01 01; 1774:147724.
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Bauer EE, Shoeman A, Buhr TJ, Daniels KM, Lyte M, Clark PJ. Voluntary binge-patterned alcohol drinking and sex-specific influences on monoamine-related neurochemical signatures in the mouse gut and brain. Alcohol Clin Exp Res. 2021 05; 45(5):996-1012.
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Jin B, Ha SE, Wei L, Singh R, Zogg H, Clemmensen B, Heredia DJ, Gould TW, Sanders KM, Ro S. Colonic Motility Is Improved by the Activation of 5-HT2B Receptors on Interstitial Cells of Cajal in Diabetic Mice. Gastroenterology. 2021 08; 161(2):608-622.e7.
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Wan J, Peng W, Li X, Qian T, Song K, Zeng J, Deng F, Hao S, Feng J, Zhang P, Zhang Y, Zou J, Pan S, Shin M, Venton BJ, Zhu JJ, Jing M, Xu M, Li Y. A genetically encoded sensor for measuring serotonin dynamics. Nat Neurosci. 2021 05; 24(5):746-752.
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Ha S, Jin B, Clemmensen B, Park P, Mahboob S, Gladwill V, Lovely FM, Gottfried-Blackmore A, Habtezion A, Verma S, Ro S. Serotonin is elevated in COVID-19-associated diarrhoea. Gut. 2021 10; 70(10):2015-2017.
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