 NF-kappa B
"NF-kappa B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
| Descriptor ID |
D016328
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| MeSH Number(s) |
D12.776.260.600 D12.776.660.600 D12.776.930.600
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| Concept/Terms |
NF-kappa B- NF-kappa B
- kappa B Enhancer Binding Protein
- NF-kappaB
- NF kappaB
- Transcription Factor NF-kB
- Factor NF-kB, Transcription
- NF-kB, Transcription Factor
- Transcription Factor NF kB
- NF-kB
- NF kB
- Immunoglobulin Enhancer-Binding Protein
- Enhancer-Binding Protein, Immunoglobulin
- Immunoglobulin Enhancer Binding Protein
- Nuclear Factor kappa B
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Below are MeSH descriptors whose meaning is more general than "NF-kappa B".
Below are MeSH descriptors whose meaning is more specific than "NF-kappa B".
This graph shows the total number of publications written about "NF-kappa B" by people in this website by year, and whether "NF-kappa B" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1995 | 4 | 1 | 5 | | 1996 | 4 | 2 | 6 | | 1997 | 4 | 3 | 7 | | 1998 | 2 | 1 | 3 | | 1999 | 1 | 6 | 7 | | 2000 | 8 | 2 | 10 | | 2001 | 4 | 3 | 7 | | 2002 | 6 | 8 | 14 | | 2003 | 12 | 10 | 22 | | 2004 | 12 | 7 | 19 | | 2005 | 10 | 15 | 25 | | 2006 | 5 | 10 | 15 | | 2007 | 6 | 16 | 22 | | 2008 | 6 | 16 | 22 | | 2009 | 9 | 12 | 21 | | 2010 | 5 | 12 | 17 | | 2011 | 3 | 16 | 19 | | 2012 | 6 | 15 | 21 | | 2013 | 6 | 13 | 19 | | 2014 | 12 | 16 | 28 | | 2015 | 6 | 5 | 11 | | 2016 | 2 | 11 | 13 | | 2017 | 3 | 7 | 10 | | 2018 | 4 | 3 | 7 | | 2019 | 3 | 11 | 14 | | 2020 | 6 | 4 | 10 | | 2021 | 7 | 5 | 12 | | 2022 | 1 | 5 | 6 | | 2023 | 2 | 5 | 7 | | 2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "NF-kappa B" by people in Profiles.
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Grayck MR, McCarthy WC, Solar M, Balasubramaniyan N, Zheng L, Orlicky DJ, Wright CJ. Implications of neonatal absence of innate immune mediated NF?B/AP1 signaling in the murine liver. Pediatr Res. 2024 Jun; 95(7):1791-1802.
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Schlein LJ, Brill SA, Brady RV, Farrell KB, Rose BJ, Meuten TK, Jordan CT, Thamm DH. Parthenolide As a Therapeutic for Disseminated Canine Neoplasms. J Pharmacol Exp Ther. 2024 02 15; 388(3):774-787.
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Grayck MR, McCarthy WC, Solar M, Golden E, Balasubramaniyan N, Zheng L, Sherlock LG, Wright CJ. GSK3?/NF-?B -dependent transcriptional regulation of homeostatic hepatocyte Tnf production. Am J Physiol Gastrointest Liver Physiol. 2024 Apr 01; 326(4):G374-G384.
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Garcia VP, Fandl HK, Hijmans JG, Berry AR, Cardenas HL, Stockelman KA, DeSouza NM, Treuth JW, Greiner JJ, Park AJ, Stauffer BL, DeSouza CA. Effects of circulating endothelial microvesicles isolated from adults with obesity on endothelial cell inflammation, apoptosis, and nitric oxide production. Am J Physiol Endocrinol Metab. 2024 01 01; 326(1):E38-E49.
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Miranda ER, Mey JT, Blackburn BK, Chaves AB, Fuller KNZ, Perkins RK, Ludlow AT, Haus JM. Soluble RAGE and skeletal muscle tissue RAGE expression profiles in lean and obese young adults across differential aerobic exercise intensities. J Appl Physiol (1985). 2023 10 01; 135(4):849-862.
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Ghosh S, Devereaux MW, Orlicky DJ, Sokol RJ. Pharmacologic inhibition of HNF4a prevents parenteral nutrition associated cholestasis in mice. Sci Rep. 2023 05 12; 13(1):7752.
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McCarthy WC, Sherlock LG, Grayck MR, Zheng L, Lacayo OA, Solar M, Orlicky DJ, Dobrinskikh E, Wright CJ. Innate Immune Zonation in the Liver: NF-?B (p50) Activation and C-Reactive Protein Expression in Response to Endotoxemia Are Zone Specific. J Immunol. 2023 05 01; 210(9):1372-1385.
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Hammad AM, Alzaghari LF, Alfaraj M, Al-Shawaf L, Sunoqrot S. Nanoassemblies from the aqueous extract of roasted coffee beans modulate the behavioral and molecular effects of smoking withdrawal-induced anxiety in female rats. Drug Deliv Transl Res. 2023 07; 13(7):1967-1982.
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Fandl HK, Garcia VP, Treuth JW, Brewster LM, Greiner JJ, Davy KP, Stauffer BL, Desouza CA. Endothelial-derived extracellular vesicles from obese/hypertensive adults increase factors associated with hypertrophy and fibrosis in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2023 05 01; 324(5):H675-H685.
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Holmberg R, Robinson M, Gilbert SF, Lujano-Olazaba O, Waters JA, Kogan E, Velasquez CLR, Stevenson D, Cruz LS, Alexander LJ, Lara J, Mu EM, Camillo JR, Bitler BG, Huxford T, House CD. TWEAK-Fn14-RelB Signaling Cascade Promotes Stem Cell-like Features that Contribute to Post-Chemotherapy Ovarian Cancer Relapse. Mol Cancer Res. 2023 02 01; 21(2):170-186.
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