 Norepinephrine
"Norepinephrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
| Descriptor ID |
D009638
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| MeSH Number(s) |
D02.033.100.291.502 D02.092.063.480 D02.092.211.215.311.560 D02.092.311.830
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| Concept/Terms |
Norepinephrine- Norepinephrine
- Noradrenaline
- Levarterenol
- Levonorepinephrine
Levophed- Levophed
- Levophed Bitartrate
- Bitartrate, Levophed
Norepinephrine Bitartrate- Norepinephrine Bitartrate
- Bitartrate, Norepinephrine
- Norepinephrine l-Tartrate (1:1)
- Noradrenaline Bitartrate
- Bitartrate, Noradrenaline
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Below are MeSH descriptors whose meaning is more general than "Norepinephrine".
Below are MeSH descriptors whose meaning is more specific than "Norepinephrine".
This graph shows the total number of publications written about "Norepinephrine" by people in this website by year, and whether "Norepinephrine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 1 | 3 | | 1997 | 2 | 3 | 5 | | 1998 | 1 | 0 | 1 | | 1999 | 2 | 0 | 2 | | 2000 | 0 | 3 | 3 | | 2001 | 1 | 4 | 5 | | 2002 | 1 | 7 | 8 | | 2003 | 2 | 2 | 4 | | 2004 | 1 | 3 | 4 | | 2005 | 2 | 10 | 12 | | 2006 | 2 | 3 | 5 | | 2007 | 0 | 4 | 4 | | 2008 | 0 | 3 | 3 | | 2009 | 2 | 2 | 4 | | 2010 | 0 | 3 | 3 | | 2011 | 3 | 2 | 5 | | 2012 | 3 | 1 | 4 | | 2013 | 0 | 2 | 2 | | 2014 | 1 | 3 | 4 | | 2015 | 2 | 3 | 5 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 5 | 6 | | 2018 | 3 | 2 | 5 | | 2019 | 3 | 0 | 3 | | 2020 | 0 | 2 | 2 | | 2021 | 1 | 3 | 4 | | 2022 | 0 | 4 | 4 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 4 | 5 | | 2025 | 2 | 2 | 4 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Norepinephrine" by people in Profiles.
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Rohner VL, Curreli S, Lamothe-Molina PJ, Kagiampaki Z, Yee AG, Nardin C, Eschholz L, Dieter A, Foustoukos G, Milanese P, Banterle L, Childs T, Canziani A, Dernic J, Ravotto L, Bhat MA, Sönmez L, Wasielewski LM, Ziebarth T, Molnar MI, Huang G, Masseck OA, Weber B, Reiner A, Lüthi A, Ford CP, Wiegert JS, Ruediger S, Fellin T, Patriarchi T. Next-generation multicolor indicators for in vivo imaging of norepinephrine. Nat Methods. 2026 Mar; 23(3):636-652.
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Ogg MC, Lansdell BJ, Franks HT, Hughes AC, Lee J, Nolen HG, Shirinifard A, Schwarz LA. Locus coeruleus norepinephrine neurons facilitate orbitofrontal cortex remapping and behavioral flexibility. Cell Rep. 2025 Dec 23; 44(12):116687.
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Seel RT, Arciniegas DB, Macciocchi SP, Cifu DX, Frazier YG, Kaelin DL, Katz DI, Oyesanya TO, Pourrahmat M, Schofield T, Wagner AK, Fazeli MS. Systematic Review on Norepinephrine and Dopamine Reuptake Inhibitors for Traumatic Brain Injury-Related Symptoms: Report of the American Congress of Rehabilitation Medicine. Arch Phys Med Rehabil. 2026 04; 107(4):761-777.
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Becker LJ, Martin MM, Hughes AC, Mulvey B, Kuo CC, Piantadosi SC, Bruchas MR, Martinowich K, Meye FJ, Schwarz LA, Weinshenker D, McCall JG, Riga D. Neuropeptides as transmitters and regulators of the locus coeruleus noradrenergic system. Pharmacol Rev. 2025 09; 77(5):100081.
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Luskin AT, Li L, Fu X, Martin MM, Barcomb K, Girven KS, Blackburn T, Wells BA, Thai ST, Li EM, Rana AN, Simon RC, Sun L, Gao L, Murry AD, Golden SA, Stuber GD, Ford CP, Gu L, Bruchas MR. Heterogeneous pericoerulear neurons tune arousal and exploratory behaviours. Nature. 2025 07; 643(8071):437-447.
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Scalco A, Lee EN, Johnson MA, Sorensen ML, Hilton TN, Omonaka RK, Zeimantz S, Aicher SA, Woodward WR, Habecker BA. Hypertension-induced heart failure disrupts cardiac sympathetic innervation. Am J Physiol Heart Circ Physiol. 2024 12 01; 327(6):H1544-H1558.
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Stutsman N, Habecker B, Pavlovic N, Jurgens CY, Woodward WR, Lee CS, Denfeld QE. Sympathetic dysfunction is associated with worse fatigue and early and subtle symptoms in heart failure: an exploratory sex-stratified analysis. Eur J Cardiovasc Nurs. 2024 Jul 19; 23(5):532-539.
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Hughes AC, Pittman BG, Xu B, Gammons JW, Webb CM, Nolen HG, Chapman P, Bikoff JB, Schwarz LA. A single-vector intersectional AAV strategy for interrogating cellular diversity and brain function. Nat Neurosci. 2024 Jul; 27(7):1400-1410.
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Munroe ES, Weinstein J, Gershengorn HB, Karlic KJ, Seelye S, Sjoding MW, Valley TS, Prescott HC. Understanding How Clinicians Personalize Fluid and Vasopressor Decisions in Early Sepsis Management. JAMA Netw Open. 2024 04 01; 7(4):e247480.
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Guevara A, Smith CER, Caldwell JL, Ngo L, Mott LR, Lee IJ, Tapa S, Wang Z, Wang L, Woodward WR, Ng GA, Habecker BA, Ripplinger CM. Chronic nicotine exposure is associated with electrophysiological and sympathetic remodeling in the intact rabbit heart. Am J Physiol Heart Circ Physiol. 2024 06 01; 326(6):H1337-H1349.
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