 Nuclear Localization Signals
"Nuclear Localization Signals" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Short, predominantly basic amino acid sequences identified as nuclear import signals for some proteins. These sequences are believed to interact with specific receptors at the NUCLEAR PORE.
| Descriptor ID |
D019913
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| MeSH Number(s) |
D12.644.770.610 G02.111.570.060.670.610
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| Concept/Terms |
Nuclear Localization Signals- Nuclear Localization Signals
- Nuclear Localization Signal Peptide
- Nuclear Localization Signal
- Signal, Nuclear Localization
- Signals, Nuclear Localization
- NLS Peptide
- NLS Peptides
- Peptide, NLS
- Peptides, NLS
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Below are MeSH descriptors whose meaning is more general than "Nuclear Localization Signals".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Localization Signals".
This graph shows the total number of publications written about "Nuclear Localization Signals" by people in this website by year, and whether "Nuclear Localization Signals" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2004 | 0 | 2 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 4 | 4 | | 2014 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclear Localization Signals" by people in Profiles.
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Gaurav N, Tripathi PK, Kumar V, Chugh A, Sundd M, Patel AK. Role of nuclear localization signals in the DNA delivery function of Chikungunya virus capsid protein. Arch Biochem Biophys. 2021 05 15; 702:108822.
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Cutler AA, Jackson JB, Corbett AH, Pavlath GK. Non-equivalence of nuclear import among nuclei in multinucleated skeletal muscle cells. J Cell Sci. 2018 02 05; 131(3).
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Mohan V, Agarwal R, Singh RP. A novel alkaloid, evodiamine causes nuclear localization of cytochrome-c and induces apoptosis independent of p53 in human lung cancer cells. Biochem Biophys Res Commun. 2016 09 02; 477(4):1065-1071.
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Pratt EP, Owens JL, Hockerman GH, Hu CD. Bimolecular Fluorescence Complementation (BiFC) Analysis of Protein-Protein Interactions and Assessment of Subcellular Localization in Live Cells. Methods Mol Biol. 2016; 1474:153-70.
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Deng ZH, Gomez TS, Osborne DG, Phillips-Krawczak CA, Zhang JS, Billadeau DD. Nuclear FAM21 participates in NF-?B-dependent gene regulation in pancreatic cancer cells. J Cell Sci. 2015 Jan 15; 128(2):373-84.
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Elder RM, Jayaraman A. Molecular simulations of polycation-DNA binding exploring the effect of peptide chemistry and sequence in nuclear localization sequence based polycations. J Phys Chem B. 2013 Oct 10; 117(40):11988-99.
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Prescott JD, Poczobutt JM, Tentler JJ, Walker DM, Gutierrez-Hartmann A. Mapping of ESE-1 subdomains required to initiate mammary epithelial cell transformation via a cytoplasmic mechanism. Mol Cancer. 2011 Aug 28; 10:103.
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Adwan TS, Ohm AM, Jones DNM, Humphries MJ, Reyland ME. Regulated binding of importin-a to protein kinase Cd in response to apoptotic signals facilitates nuclear import. J Biol Chem. 2011 Oct 14; 286(41):35716-35724.
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McConnell BV, Koto K, Gutierrez-Hartmann A. Nuclear and cytoplasmic LIMK1 enhances human breast cancer progression. Mol Cancer. 2011 Jun 18; 10:75.
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Go YM, Kang SM, Roede JR, Orr M, Jones DP. Increased inflammatory signaling and lethality of influenza H1N1 by nuclear thioredoxin-1. PLoS One. 2011 Apr 15; 6(4):e18918.
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