 Lymphocyte Activation
"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
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| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.450.050.400.545 G12.565
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| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blast Transformation
- Blastogenesis
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Lymphoblast
- Lymphoblast Transformation
- Transformation, Blast
- Transformation, Lymphocyte
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Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 5 | 7 | 12 | | 1997 | 8 | 10 | 18 | | 1998 | 10 | 22 | 32 | | 1999 | 11 | 8 | 19 | | 2000 | 11 | 11 | 22 | | 2001 | 5 | 12 | 17 | | 2002 | 11 | 14 | 25 | | 2003 | 9 | 20 | 29 | | 2004 | 8 | 19 | 27 | | 2005 | 11 | 12 | 23 | | 2006 | 7 | 20 | 27 | | 2007 | 5 | 19 | 24 | | 2008 | 13 | 12 | 25 | | 2009 | 6 | 21 | 27 | | 2010 | 6 | 15 | 21 | | 2011 | 4 | 15 | 19 | | 2012 | 6 | 25 | 31 | | 2013 | 7 | 15 | 22 | | 2014 | 8 | 20 | 28 | | 2015 | 4 | 16 | 20 | | 2016 | 3 | 14 | 17 | | 2017 | 4 | 24 | 28 | | 2018 | 4 | 16 | 20 | | 2019 | 0 | 16 | 16 | | 2020 | 4 | 11 | 15 | | 2021 | 4 | 16 | 20 | | 2022 | 2 | 7 | 9 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 5 | 6 | | 2025 | 3 | 10 | 13 | | 2026 | 2 | 4 | 6 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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Maeda K, Campbell PL, Wu Q, Tsou PS, Cooney LA, Mao-Draayer Y, Fox DA, Gurrea-Rubio M. Anti-CD6 monoclonal antibody UMCD6 induces CD6 internalization, remodels costimulatory receptor availability, and modulates CD4+ T-cell activation. Front Immunol. 2026; 17:1918840.
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Ryan EK, Jenkins BJ, Bergin R, Salazar RE, Davis C, Kedia-Mehta N, Amini A, Garner LC, Flynn C, Ryan S, Perry I, Masterson JC, Heneghan H, Moynagh PN, Swatek KN, Klenerman P, Jones N, Sinclair LV, O'Shea D, Hogan AE. Rapid glycolytic metabolism underpins mucosal-associated invariant T cell functional responses to innate cytokines. J Immunol. 2026 Aug 04; 215(8).
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Smith A, Kiwanuka K, Pessenda G, Rahmberg AR, Flynn JK, Herbert R, Brenchley JM, Loke P. Hematological consequences of environmental change during dewilding of rhesus macaques. Nat Commun. 2026 Jul 10; 17(1).
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Bader CS, Killian S, Iliopoulou BP, Chen PI, Pathak S, Le CT, Villar-Prados A, Ji X, Jensen KP, Negrin RS, Meyer EH. Regulatory-like FOXP3+Helios+CD4+ T conventional cells correlate with T-cell activation after Orca-T immunotherapy. Blood. 2026 05 21; 147(21):2489-2502.
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Kendirli PK, Erdem S, Kisaarslan AP, Gök V, Kayhan E, Özcan A, Dogan ME, Klein C, Ünal E, Eken A. A novel ELF4 gene variant disrupts T and NK cell function in a patient with immune thrombocytopenia (ITP). Inflamm Res. 2026 May 19; 75(1).
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Göktas S, Kalaycik Sengul O, Erdem S, Eke Güngör H, Babayeva R, Bilgic-Eltan S, Güzel T, Dörterler K, Rohlfs M, Özcan A, Yilmaz E, Karakukcu M, Akar HH, Karakoc-Aydiner E, Özen A, Elmas M, Patiroglu T, Dogan ME, Bas H, Taylor N, Baris S, Klein C, Eken A, Ünal E. The Experience of a Tertiary Reference Center in Central Anatolia with Children Carrying ZAP-70 Variants, Including Two Novel Variants. J Clin Immunol. 2026 Mar 06; 46(1).
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Kantheti U, Shirley JL, Fry LG, Qvale AM, Olivas-Corral JG, Vankamamidi SE, Tamburini BAJ. PD-L1 cell-intrinsic signals limit immune activation during cutaneous vaccinia virus infection. J Immunol. 2026 Feb 09; 215(2).
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Ang MJY, Metzloff AE, Thatte AS, Mitchell MJ. Lipid nanoparticles for engineering next generation CAR T cell immunotherapy. Nanoscale Horiz. 2026 Jan 05; 11(1):22-36.
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Marguerie F, Saifi MA, Geary B, Barnes D, Lim L, Jonsson AH, Ho IC. Enhancement of activation-induced T cell proliferation by SIRPG in a CD47-independent manner. Front Immunol. 2025; 16:1668361.
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Albert GK, Cao P, Davila E. Leveraging innate immune signals in CD8+ T cells to boost antitumor immunity. Front Immunol. 2025; 16:1617773.
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