Myofibrils
"Myofibrils" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The long cylindrical contractile organelles of STRIATED MUSCLE cells composed of ACTIN FILAMENTS; MYOSIN filaments; and other proteins organized in arrays of repeating units called SARCOMERES .
Descriptor ID |
D009210
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MeSH Number(s) |
A10.690.552.875 A11.284.430.214.190.750.620 A11.620.249.850 A11.620.500.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Myofibrils".
Below are MeSH descriptors whose meaning is more specific than "Myofibrils".
This graph shows the total number of publications written about "Myofibrils" by people in this website by year, and whether "Myofibrils" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 | 1998 | 1 | 0 | 1 | 1999 | 0 | 1 | 1 | 2000 | 0 | 1 | 1 | 2002 | 1 | 0 | 1 | 2004 | 0 | 1 | 1 | 2009 | 1 | 0 | 1 | 2011 | 1 | 0 | 1 | 2015 | 1 | 1 | 2 | 2016 | 2 | 0 | 2 | 2017 | 0 | 1 | 1 | 2019 | 1 | 0 | 1 | 2020 | 2 | 2 | 4 | 2021 | 0 | 1 | 1 | 2022 | 1 | 0 | 1 | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myofibrils" by people in Profiles.
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Salyer LG, Salhi HE, Brundage EA, Shettigar V, Sturgill SL, Zanella H, Templeton B, Abay E, Emmer KM, Lowe J, Rafael-Fortney JA, Parinandi N, Foster DB, McKinsey TA, Woulfe KC, Ziolo MT, Biesiadecki BJ. Troponin I Tyrosine Phosphorylation Beneficially Accelerates Diastolic Function. Circ Res. 2024 01 05; 134(1):33-45.
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Lin YH, Major JL, Liebner T, Hourani Z, Travers JG, Wennersten SA, Haefner KR, Cavasin MA, Wilson CE, Jeong MY, Han Y, Gotthardt M, Ferguson SK, Ambardekar AV, Lam MP, Choudhary C, Granzier HL, Woulfe KC, McKinsey TA. HDAC6 modulates myofibril stiffness and diastolic function of the heart. J Clin Invest. 2022 05 16; 132(10).
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Knight WE, Cao Y, Lin YH, Chi C, Bai B, Sparagna GC, Zhao Y, Du Y, Londono P, Reisz JA, Brown BC, Taylor MRG, Ambardekar AV, Cleveland JC, McKinsey TA, Jeong MY, Walker LA, Woulfe KC, D'Alessandro A, Chatfield KC, Xu H, Bristow MR, Buttrick PM, Song K. Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Enables Modeling of Human Hypertrophic Cardiomyopathy. Stem Cell Reports. 2021 03 09; 16(3):519-533.
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Rice SA, Ten Have GAM, Reisz JA, Gehrke S, Stefanoni D, Frare C, Barati Z, Coker RH, D'Alessandro A, Deutz NEP, Drew KL. Nitrogen recycling buffers against ammonia toxicity from skeletal muscle breakdown in hibernating arctic ground squirrels. Nat Metab. 2020 12; 2(12):1459-1471.
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Major JL, Bagchi RA, McKinsey TA. ERRing on the Side of a Mature Heart. Circ Res. 2020 06 05; 126(12):1703-1705.
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Salvador AF, Askow AT, McKenna CF, Fang HY, Burke SK, Li Z, Ulanov AV, Paluska SA, Petruzzello SJ, Boppart MD, Oliver JM, Burd NA. Resistance Exercise-induced Regulation of Muscle Protein Synthesis to Intraset Rest. Med Sci Sports Exerc. 2020 05; 52(5):1022-1030.
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Lin YH, Schmidt W, Fritz KS, Jeong MY, Cammarato A, Foster DB, Biesiadecki BJ, McKinsey TA, Woulfe KC. Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity. J Mol Cell Cardiol. 2020 02; 139:135-147.
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Wallner M, Eaton DM, Berretta RM, Liesinger L, Schittmayer M, Gindlhuber J, Wu J, Jeong MY, Lin YH, Borghetti G, Baker ST, Zhao H, Pfleger J, Blass S, Rainer PP, von Lewinski D, Bugger H, Mohsin S, Graier WF, Zirlik A, McKinsey TA, Birner-Gruenberger R, Wolfson MR, Houser SR. HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction. Sci Transl Med. 2020 01 08; 12(525).
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Ali HR, Michel CR, Lin YH, McKinsey TA, Jeong MY, Ambardekar AV, Cleveland JC, Reisdorph R, Reisdorph N, Woulfe KC, Fritz KS. Defining decreased protein succinylation of failing human cardiac myofibrils in ischemic cardiomyopathy. J Mol Cell Cardiol. 2020 01; 138:304-317.
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Beals JW, Skinner SK, McKenna CF, Poozhikunnel EG, Farooqi SA, van Vliet S, Martinez IG, Ulanov AV, Li Z, Paluska SA, Burd NA. Altered anabolic signalling and reduced stimulation of myofibrillar protein synthesis after feeding and resistance exercise in people with obesity. J Physiol. 2018 11; 596(21):5119-5133.
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