Genetic Therapy
"Genetic Therapy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Techniques and strategies which include the use of coding sequences and other conventional or radical means to transform or modify cells for the purpose of treating or reversing disease conditions.
| Descriptor ID |
D015316
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| MeSH Number(s) |
E02.095.301 E05.393.420.301
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| Concept/Terms |
Genetic Therapy- Genetic Therapy
- Genetic Therapies
- Therapies, Genetic
- Therapy, Genetic
- Therapy, DNA
- DNA Therapy
Genetic Therapy, Somatic- Genetic Therapy, Somatic
- Genetic Therapies, Somatic
- Somatic Genetic Therapies
- Somatic Genetic Therapy
- Therapies, Somatic Genetic
- Therapy, Somatic Genetic
Genetic Therapy, Gametic- Genetic Therapy, Gametic
- Gametic Genetic Therapies
- Gametic Genetic Therapy
- Genetic Therapies, Gametic
- Therapies, Gametic Genetic
- Therapy, Gametic Genetic
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Below are MeSH descriptors whose meaning is more general than "Genetic Therapy".
Below are MeSH descriptors whose meaning is more specific than "Genetic Therapy".
This graph shows the total number of publications written about "Genetic Therapy" by people in this website by year, and whether "Genetic Therapy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 5 | 1 | 6 | | 1997 | 3 | 5 | 8 | | 1998 | 4 | 1 | 5 | | 1999 | 2 | 5 | 7 | | 2000 | 5 | 4 | 9 | | 2001 | 3 | 3 | 6 | | 2002 | 4 | 5 | 9 | | 2003 | 6 | 7 | 13 | | 2004 | 5 | 2 | 7 | | 2005 | 7 | 5 | 12 | | 2006 | 3 | 6 | 9 | | 2007 | 7 | 3 | 10 | | 2008 | 10 | 5 | 15 | | 2009 | 9 | 3 | 12 | | 2010 | 1 | 2 | 3 | | 2011 | 4 | 3 | 7 | | 2012 | 4 | 1 | 5 | | 2013 | 1 | 4 | 5 | | 2014 | 7 | 7 | 14 | | 2015 | 1 | 4 | 5 | | 2016 | 2 | 5 | 7 | | 2017 | 3 | 1 | 4 | | 2018 | 6 | 2 | 8 | | 2019 | 3 | 5 | 8 | | 2020 | 6 | 3 | 9 | | 2021 | 6 | 4 | 10 | | 2022 | 1 | 2 | 3 | | 2023 | 1 | 11 | 12 | | 2024 | 7 | 3 | 10 | | 2025 | 6 | 4 | 10 | | 2026 | 5 | 2 | 7 |
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Below are the most recent publications written about "Genetic Therapy" by people in Profiles.
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Mitchell JJ, Abdenur JE, de Boer F, Boyer M, Breilyn MS, Couce ML, De Leon DD, Derks TG, El-Gharbawy A, Haijer-Schreuder AB, Loechner K, Longo N, Lund AM, Olmos MAM, McCandless SE, de Oliveira BM, Mount M, Muschol N, Pytlak K, Radhakrishnan K, Riba-Wolman R, Rodriguez-Buritica DF, La Rosa A, Rossi A, Saavedra H, Santer R, Shayota B, Smit GPA, Moura De Souza CF, van der Klauw MM, Weinstein DA, Wolfsdorf JI, Blake A, Grimm AA, Mitragotri D, Rahman S, Turner-Bowker DM, Collis R. Phase 3 Randomized Trial Results of DTX401 AAV Gene Therapy for the Treatment of GSDIa. J Inherit Metab Dis. 2026 Sep; 49(5):e70241.
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Aartsma-Rus A, de Gusmao CM, Demarest S, van Roon-Mom W, Graessner H, Bush LW, Kogel C, Yu TW, Synofzik M, Schuele R. Individualized antisense oligonucleotide treatment eligibility of patients living with neurodevelopmental diseases. Cell Rep Med. 2026 Sep 15; 7(9):102989.
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Calton MA, Croze RH, Sullivan TH, Collins SA, Tucker S, Whittlesey KJ, Kim DH, Nye JA, Beliakoff G, Quezada M, Burns C, Schmitt C, Klein A, Jia V, Kovacs L, Lauko D, Yoh K, Nguyen K, Barglow K, Gonzales J, Khoday D, Mason T, Delaria K, Bashour K, Kotterman M, Schaffer D, Song A, Francis P, Taylor-Cousar JL, Kirn D. Design and characterization of 4D-710, an aerosolized gene therapy for cystic fibrosis lung disease. Am J Respir Cell Mol Biol. 2026 Jul 01; 74(7):837-846.
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Barbon E, Simoni C, Argabright A, Boettiger M, Negri C, Manta E, Raimondi A, Vezzoli E, Canepari C, Biffi M, Nonis A, Gazzo F, Benedicenti F, Montini E, la Marca G, Sanvito F, Smith J, D'Alessandro A, Cantore A. Liver-directed lentiviral gene therapy confers durable hepatic and systemic amelioration of methylmalonic acidemia in mice. J Hepatol. 2026 Sep; 85(3):567-582.
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Nolen N, Aartsma-Rus A, Caneva C, Coughlin Ii CR, Cousin MA, Douthwright C, Graessner H, Kim-McManus O, Kuniholm A, Leonard S, Martinsen A, Meserve M, Synofzik M, Yandava B, Yu TW, Demarest S, Paxton RJ. Paying for precision: funding approaches for N-of-1 trials of individualized gene targeted therapies. Orphanet J Rare Dis. 2026 May 21; 21(1).
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Crooke ST, Glass S, Gleeson JG, Mignon L, Skourti-Stathaki K, Douville J, Knutsen M, Pu H, Bain JM, Berry-Kravis E, Shneider NA, Kim-McManus O, Eichler FS, Chung WK, Nagy A, Kaufmann H, Gonzalez-Duarte A, Oskarsson B, McCourt EA, Leung N. Addressing the needs of nano-rare patients: the n-Lorem experience. Nucleic Acids Res. 2026 May 20; 54(10).
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Palomba ML, Schuster SJ, Karmali R, Skarbnik AP, Abramson JS, Ardeshna K, Borchmann P, Hill BT, GarcĂa-Sancho AM, Marcacci G, Rapoport AP, Cartron G, Fleury I, Izutsu K, Kamdar M, Mielke S, Barbui AM, Ortega JLR, Nastoupil LJ, Ahmed S, Bar M, Diaz L, Furustrand U, Diab V, Vedal M, Avilion A, Kumar J, Nishii R, Colicino S, Morschhauser F. Lisocabtagene maraleucel in patients with relapsed or refractory marginal zone lymphoma (TRANSCEND FL): primary analysis results from the global, multicohort, single-arm, phase 2 study. Lancet. 2026 Mar 07; 407(10532):963-975.
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Chen CY, Hadla M, Khambati I, Kashyap S, Westerfield V, Fedeles S, Besse W, Hopp K, Harris PC, Patel V, Chini E, Salih M, Barry MA, Chebib FT. Emerging Therapies in Autosomal Dominant Polycystic Kidney Disease. Kidney360. 2026 Jul 01; 7(7):1662-1676.
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Spira AI, Berz D, Jotte RM, Pachipala KK, Berger MS. Dose Escalation Trial of the Combination of Osimertinib and Quaratusugene Ozeplasmid Gene Therapy in Patients with Advanced NSCLC. Clin Lung Cancer. 2026 Jan; 27(1):75-81.
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Wang S, Zhang P, Sun Y, Fang Y, Wang P, Shao M, Zhang N, Shi S, Chen X, Gao H, Cheng J, Gao B, Liu T, Qian Q, Song C. Engineering of BZ transposase and transposon donor vector for enhanced efficiency and safety in gene delivery applications. Nucleic Acids Res. 2025 Sep 23; 53(18).
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