Homeodomain Proteins
"Homeodomain Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (GENE EXPRESSION REGULATION, DEVELOPMENTAL).
| Descriptor ID |
D018398
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| MeSH Number(s) |
D12.776.260.400
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| Concept/Terms |
Homeodomain Proteins- Homeodomain Proteins
- Proteins, Homeodomain
- Homeo Domain Proteins
- Proteins, Homeo Domain
- Homeotic Proteins
- Proteins, Homeotic
- Homeobox Proteins
- Proteins, Homeobox
- Homeoproteins
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Below are MeSH descriptors whose meaning is more general than "Homeodomain Proteins".
Below are MeSH descriptors whose meaning is more specific than "Homeodomain Proteins".
This graph shows the total number of publications written about "Homeodomain Proteins" by people in this website by year, and whether "Homeodomain Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 6 | 0 | 6 | | 1997 | 3 | 2 | 5 | | 1998 | 4 | 5 | 9 | | 1999 | 2 | 6 | 8 | | 2000 | 3 | 3 | 6 | | 2001 | 4 | 2 | 6 | | 2002 | 6 | 2 | 8 | | 2003 | 3 | 8 | 11 | | 2004 | 10 | 6 | 16 | | 2005 | 7 | 4 | 11 | | 2006 | 12 | 7 | 19 | | 2007 | 9 | 6 | 15 | | 2008 | 8 | 8 | 16 | | 2009 | 15 | 11 | 26 | | 2010 | 7 | 12 | 19 | | 2011 | 12 | 7 | 19 | | 2012 | 13 | 16 | 29 | | 2013 | 11 | 13 | 24 | | 2014 | 10 | 8 | 18 | | 2015 | 11 | 5 | 16 | | 2016 | 7 | 2 | 9 | | 2017 | 9 | 8 | 17 | | 2018 | 9 | 3 | 12 | | 2019 | 9 | 4 | 13 | | 2020 | 7 | 4 | 11 | | 2021 | 4 | 5 | 9 | | 2022 | 3 | 6 | 9 | | 2023 | 4 | 3 | 7 | | 2024 | 1 | 7 | 8 | | 2025 | 1 | 1 | 2 | | 2026 | 4 | 2 | 6 |
To return to the timeline, click here.
Below are the most recent publications written about "Homeodomain Proteins" by people in Profiles.
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Morcom L, Xia W, Xu Z, Awasthi Y, Geywitz C, Ellis MO, Noli T, Zulji A, Yamamoto D, Girdler GC, Kai L, Zhu K, Wei M, Tang XY, Hoi KK, Gonzalez-Maya J, Duncan GJ, Vaquie AM, Gold Diaz D, Kawaguchi R, Liu E, Sun Y, Yang D, Jordan GD, Lu IL, Holmqvist S, Bartels T, Ridley K, Choi JJ, Franco SJ, Huang EJ, Emery B, Geschwind D, Schirmer L, Balmus G, Popko B, Fancy SPJ, Rowitch DH. DNA damage burden causes selective CUX2 neuron loss in neuroinflammation. Nature. 2026 May; 653(8115):809-818.
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Xia W, Morcom L, Xu Z, Lu IL, Wang Q, Hoi KK, Wei M, Zhu K, Jordan G, Tang XY, Gonzalez-Maya J, Mattera VS, Panigrahi SM, Kawaguchi R, Emery B, Franco SJ, Geschwind DH, Popko B, Rowitch DH, Fancy SPJ. Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair. Nature. 2026 May; 653(8115):819-830.
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Denson AM, Rodriguez KE, Letourneau-Freiberg LR, Kandasamy B, Naylor RN, Abdullatif HD, Benjamin RW, Cobry E, Freemark MS, Thomas IH, Greeley SAW. Children With Pancreatic Hypoplasia Experience Poor Weight Gain and Labile Diabetes but Low Incidence of DKA. J Clin Endocrinol Metab. 2026 Mar 17; 111(4):e1164-e1173.
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Jang S, Abarinov EV, Dobkin JA, Hurley EC, Closser M, Sussel L, Wichterle H. Independent control of neurogenesis and dorsoventral patterning by NKX2-2. Genes Dev. 2026 03 02; 40(5-6):384-395.
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Clayfield L, Malik D, Whittle J, Xu J, Mevel R, Fadlullah MZH, Patel R, Szpakowska M, Maqbool MA, Jones M, Lie-A-Ling M, Chevigne A, Paggetti J, Moussay E, Baker SM, Iqbal M, Maire P, Somervaille TCP, Ford HL, Kouskoff V, Largeot A, Lacaud G. Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia. Cell Rep. 2026 Feb 24; 45(2):116875.
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Arena KA, Kearns CA, Ahmed M, O'Rourke R, Sagerström CG, Franco SJ, Appel B. Gsx2 regulates oligodendrocyte precursor formation in the zebrafish spinal cord. Dev Biol. 2026 Mar; 531:30-44.
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Lamolinara A, Di Lisio C, Hixon JA, Simeone P, De Cola A, Falco MD, Meyer TJ, Ferrone A, Genovesi D, Lanuti P, Li W, De Laurenzi V, Iezzi M, Aiello FB, Durum SK. IL-7 promotes the formation of DNA double strand breaks and DNA repair in murine pro-B cells. Front Immunol. 2025; 16:1633892.
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Brooks EP, Casey MR, Wells KL, Liu TY, Van Orman M, Sussel L. NKX2.2 and KLF4 cooperate to regulate a-cell identity. Genes Dev. 2025 02 03; 39(3-4):242-260.
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Bosquez Huerta NA, Lee ZF, Christine Song EA, Woo J, Cheng YT, Sardar D, Sert O, Maleki E, Yu K, Akdemir ES, Sanchez K, Jo J, Rasband MN, Lee HK, Harmanci AS, Deneen B. Sex-specific astrocyte regulation of spinal motor circuits by Nkx6.1. Cell Rep. 2025 01 28; 44(1):115121.
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Rodrigues Sousa E, de Brot S, Zoni E, Zeinali S, Brunello A, Scarpa M, De Menna M, La Manna F, Abey Alexander A, Klima I, Freeman DW, Gates BL, Cristaldi DA, Guenat OT, Kruithof BPT, Spike BT, Chouvardas P, Kruithof-de Julio M. CRIPTO's multifaceted role in driving aggressive prostate cancer unveiled by in vivo, organoid, and patient data. Oncogene. 2025 Mar; 44(7):462-475.
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