 Myogenic Regulatory Factors
"Myogenic Regulatory Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of muscle-specific transcription factors which bind to DNA in control regions and thus regulate myogenesis. All members of this family contain a conserved helix-loop-helix motif which is homologous to the myc family proteins. These factors are only found in skeletal muscle. Members include the myoD protein (MYOD PROTEIN); MYOGENIN; myf-5, and myf-6 (also called MRF4 or herculin).
| Descriptor ID |
D018006
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| MeSH Number(s) |
D12.776.210.500.570 D12.776.260.103.750 D12.776.930.125.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Myogenic Regulatory Factors".
Below are MeSH descriptors whose meaning is more specific than "Myogenic Regulatory Factors".
This graph shows the total number of publications written about "Myogenic Regulatory Factors" by people in this website by year, and whether "Myogenic Regulatory Factors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 2000 | 2 | 7 | 9 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 2 | 2 | | 2003 | 1 | 2 | 3 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 4 | 4 | | 2006 | 3 | 2 | 5 | | 2007 | 3 | 0 | 3 | | 2008 | 2 | 1 | 3 | | 2009 | 1 | 1 | 2 | | 2010 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myogenic Regulatory Factors" by people in Profiles.
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Brunetti TM, Fremin BJ, Cripps RM. Identification of singles bar as a direct transcriptional target of Drosophila Myocyte enhancer factor-2 and a regulator of adult myoblast fusion. Dev Biol. 2015 May 15; 401(2):299-309.
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Yeung F, Chung E, Guess MG, Bell ML, Leinwand LA. Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos. Nucleic Acids Res. 2012 Aug; 40(15):7303-18.
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Backs J, Worst BC, Lehmann LH, Patrick DM, Jebessa Z, Kreusser MM, Sun Q, Chen L, Heft C, Katus HA, Olson EN. Selective repression of MEF2 activity by PKA-dependent proteolysis of HDAC4. J Cell Biol. 2011 Oct 31; 195(3):403-15.
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Shah AP, Nongthomba U, Kelly Tanaka KK, Denton ML, Meadows SM, Bancroft N, Molina MR, Cripps RM. Cardiac remodeling in Drosophila arises from changes in actin gene expression and from a contribution of lymph gland-like cells to the heart musculature. Mech Dev. 2011 Mar-Apr; 128(3-4):222-33.
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Ackert-Bicknell CL, Karasik D, Li Q, Smith RV, Hsu YH, Churchill GA, Paigen BJ, Tsaih SW. Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map. J Bone Miner Res. 2010 Aug; 25(8):1808-20.
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Liu M, Stevens-Lapsley JE, Jayaraman A, Ye F, Conover C, Walter GA, Bose P, Thompson FJ, Borst SE, Vandenborne K. Impact of treadmill locomotor training on skeletal muscle IGF1 and myogenic regulatory factors in spinal cord injured rats. Eur J Appl Physiol. 2010 Jul; 109(4):709-20.
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Calalb MB, McKinsey TA, Newkirk S, Huynh K, Sucharov CC, Bristow MR. Increased phosphorylation-dependent nuclear export of class II histone deacetylases in failing human heart. Clin Transl Sci. 2009 Oct; 2(5):325-32.
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Schwieger M, Sch?ler A, Forster M, Engelmann A, Arnold MA, Delwel R, Valk PJ, L?hler J, Slany RK, Olson EN, Stocking C. Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C. Blood. 2009 Sep 17; 114(12):2476-88.
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Carnegie GK, Soughayer J, Smith FD, Pedroja BS, Zhang F, Diviani D, Bristow MR, Kunkel MT, Newton AC, Langeberg LK, Scott JD. AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway. Mol Cell. 2008 Oct 24; 32(2):169-79.
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Kim MS, Fielitz J, McAnally J, Shelton JM, Lemon DD, McKinsey TA, Richardson JA, Bassel-Duby R, Olson EN. Protein kinase D1 stimulates MEF2 activity in skeletal muscle and enhances muscle performance. Mol Cell Biol. 2008 Jun; 28(11):3600-9.
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