| 
																	
																		 
																		 Aging
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"Aging" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
    
			 
				
				
					
						| Descriptor ID | D000375 |  
						| MeSH Number(s) | G07.345.124 |  
						| Concept/Terms |  |  
				Below are MeSH descriptors whose meaning is more general than "Aging". 
				Below are MeSH descriptors whose meaning is more specific than "Aging". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "Aging" by people in this website by year, and whether "Aging" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 1995 | 14 | 3 | 17 |  | 1996 | 8 | 3 | 11 |  | 1997 | 16 | 7 | 23 |  | 1998 | 18 | 7 | 25 |  | 1999 | 13 | 5 | 18 |  | 2000 | 19 | 5 | 24 |  | 2001 | 22 | 11 | 33 |  | 2002 | 33 | 14 | 47 |  | 2003 | 29 | 10 | 39 |  | 2004 | 22 | 8 | 30 |  | 2005 | 20 | 13 | 33 |  | 2006 | 23 | 17 | 40 |  | 2007 | 20 | 18 | 38 |  | 2008 | 32 | 14 | 46 |  | 2009 | 35 | 16 | 51 |  | 2010 | 28 | 15 | 43 |  | 2011 | 33 | 15 | 48 |  | 2012 | 35 | 12 | 47 |  | 2013 | 33 | 14 | 47 |  | 2014 | 36 | 15 | 51 |  | 2015 | 47 | 17 | 64 |  | 2016 | 48 | 16 | 64 |  | 2017 | 39 | 10 | 49 |  | 2018 | 45 | 17 | 62 |  | 2019 | 46 | 11 | 57 |  | 2020 | 32 | 19 | 51 |  | 2021 | 24 | 38 | 62 |  | 2022 | 9 | 24 | 33 |  | 2023 | 9 | 33 | 42 |  | 2024 | 28 | 27 | 55 |  | 2025 | 32 | 8 | 40 | 
 
                    To return to the timeline, click here. 
				Below are the most recent publications written about "Aging" by people in Profiles. 		
					
								
								Larson EA, Kaiser BW, Reed EL, Gibson BM, Abbotts KSS, Kenney WL, Minson CT, Halliwill JR. Systemic cardiovascular and carotid baroreflex support of arterial pressure during recovery from passive heat stress in young and older adults. Physiol Rep. 2025 Sep; 13(17):e70554.
								DeSouza CS, Stockelman KA, Hijmans JG, Bammert TD, Lincenburg GM, Greiner JJ, Garcia VP, Stauffer BL, DeSouza CA. Circulating endothelial extracellular vesicles progressively increase with age and are associated with endothelial vasodilator dysfunction. Am J Physiol Regul Integr Comp Physiol. 2025 Oct 01; 329(4):R509-R514.
								Stamenkovic S, Schmid F, Gurler G, Abolmaali F, Weitermann NA, Takasaki KT, Bonney SK, Sosa MJ, Bennett HC, Kim Y, Waters J, Shih AY. Impaired capillary-venous drainage contributes to gliosis and demyelination in mouse white matter during aging. Nat Neurosci. 2025 Sep; 28(9):1868-1882.
								Foote IF, Flint JP, Fürtjes AE, Lawrence JM, Mullin DS, Fisk JD, Karakach TK, Rutenberg A, Martin NG, Lupton MK, Llewellyn DJ, Ranson JM, Cox SR, Luciano M, Rockwood K, Grotzinger AD. Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling. Nat Genet. 2025 Aug; 57(8):1848-1859.
								Kines KT, Fairchild HR, Elder AM, Cozzens LM, Strugar ZP, Wessells VM, Becks AR, Porter WW, Borges VF, Lyons TR. Aging-induced semaphorin 7a promotes TGF-ß1-mediated cell plasticity and breast tumor metastases. Cell Rep. 2025 Aug 26; 44(8):116042.
								El-Merhie N, Staab-Weijnitz CA, Burgess JK, Kwapiszewska G. Beyond classical collagen: basement membrane collagen IV in age-associated lung diseases. Eur Respir Rev. 2025 Jul; 34(177).
								Fürtjes AE, Foote IF, Xia C, Davies G, Moodie J, Taylor A, Liewald DC, Redmond P, Corley J, McIntosh AM, Whalley HC, Muñoz Maniega S, Valdés Hernández M, Backhouse E, Ferguson K, Bastin ME, Wardlaw J, de la Fuente J, Grotzinger AD, Luciano M, Hill WD, Deary IJ, Tucker-Drob EM, Cox SR. Measurement characteristics and genome-wide correlates of lifetime brain atrophy estimated from a single MRI. Nat Commun. 2025 Jul 21; 16(1):6725.
								Chatterjee S, Ghosh S, Sin Z, Babu VS, Preval LV, Davis E, Tran N, Bammidi S, Gautam P, Hose S, Sergeev Y, Flores-Bellver M, Ritter K, Jessen HJ, Al Diri I, Sinha D, Guha P. Age-Dependent Histone Deacetylase 3 Regulation by ßA3/A1-Crystallin and Inositol Hexaphosphate in Retinal Pigmented Epithelial Cells Reveals a Novel Pathway in Age-Related Macular Degeneration. Aging Cell. 2025 Sep; 24(9):e70163.
								Henry CJ, DeGregori J. Modelling the ageing dependence of cancer evolutionary trajectories. Nat Rev Cancer. 2025 Oct; 25(10):757-780.
								Wang E, Rossman MJ, Groot HJ, Garten RS, Jarrett CL, Helgerud J, Hoff J, Richardson RS. Leg vascular function with advancing age in men: the impact of physical activity and endurance exercise training. J Appl Physiol (1985). 2025 Aug 01; 139(2):473-481. | 
																	
																		
																			
																					People  People who have written about this concept._ 
    
        Similar Concepts   
        People who have written about this concept.
     _ 
    
        Top Journals   
        Top journals in which articles about this concept have been published.
     |