 Ventricular Myosins
"Ventricular Myosins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Isoforms of MYOSIN TYPE II, specifically found in the ventricular muscle of the HEART. Defects in the genes encoding ventricular myosins result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
| Descriptor ID |
D024723
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| MeSH Number(s) |
D05.750.078.730.475.475.124.500 D08.811.277.040.025.193.750.750.124.500 D12.776.210.500.600.470.249.500 D12.776.220.525.475.475.124.500
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| Concept/Terms |
Ventricular Myosins- Ventricular Myosins
- Myosins, Ventricular
- Ventricular Myosin
- Myosin, Ventricular
- Ventricular Isomyosins
- Isomyosins, Ventricular
Ventricular alpha-Myosin- Ventricular alpha-Myosin
- Ventricular alpha Myosin
- alpha-Myosin, Ventricular
- Myosin V1
- Ventricular Cardiac alpha-Myosin
- Cardiac alpha-Myosin, Ventricular
- Ventricular Cardiac alpha Myosin
- alpha-Myosin, Ventricular Cardiac
- alpha-Myosin
- alpha Myosin
- Cardiac alpha-Myosin
- Cardiac alpha Myosin
- alpha-Myosin, Cardiac
Ventricular beta-Myosin- Ventricular beta-Myosin
- Ventricular beta Myosin
- beta-Myosin, Ventricular
- beta-Myosin
- beta Myosin
- Ventricular Cardiac beta-Myosin
- Cardiac beta-Myosin, Ventricular
- Ventricular Cardiac beta Myosin
- beta-Myosin, Ventricular Cardiac
- Myosin V3
- Cardiac beta-Myosin
- Cardiac beta Myosin
- beta-Myosin, Cardiac
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Below are MeSH descriptors whose meaning is more general than "Ventricular Myosins".
Below are MeSH descriptors whose meaning is more specific than "Ventricular Myosins".
This graph shows the total number of publications written about "Ventricular Myosins" by people in this website by year, and whether "Ventricular Myosins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2003 | 1 | 2 | 3 | | 2004 | 2 | 1 | 3 | | 2005 | 2 | 0 | 2 | | 2009 | 3 | 0 | 3 | | 2012 | 2 | 0 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ventricular Myosins" by people in Profiles.
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Vera CD, Johnson CA, Walklate J, Adhikari A, Svicevic M, Mijailovich SM, Combs AC, Langer SJ, Ruppel KM, Spudich JA, Geeves MA, Leinwand LA. Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties. J Biol Chem. 2019 11 15; 294(46):17451-17462.
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Liu R, Correll RN, Davis J, Vagnozzi RJ, York AJ, Sargent MA, Nairn AC, Molkentin JD. Cardiac-specific deletion of protein phosphatase 1? promotes increased myofilament protein phosphorylation and contractile alterations. J Mol Cell Cardiol. 2015 Oct; 87:204-13.
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Karabina A, Kazmierczak K, Szczesna-Cordary D, Moore JR. Myosin regulatory light chain phosphorylation enhances cardiac ?-myosin in vitro motility under load. Arch Biochem Biophys. 2015 Aug 15; 580:14-21.
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Xu X, Roe ND, Weiser-Evans MC, Ren J. Inhibition of mammalian target of rapamycin with rapamycin reverses hypertrophic cardiomyopathy in mice with cardiomyocyte-specific knockout of PTEN. Hypertension. 2014 Apr; 63(4):729-39.
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McKee LA, Chen H, Regan JA, Behunin SM, Walker JW, Walker JS, Konhilas JP. Sexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy mice. Arch Biochem Biophys. 2013 Jul 01; 535(1):39-48.
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Thompson RC, Buvoli M, Buvoli A, Leinwand LA. Myosin filament assembly requires a cluster of four positive residues located in the rod domain. FEBS Lett. 2012 Sep 21; 586(19):3008-12.
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Deacon JC, Bloemink MJ, Rezavandi H, Geeves MA, Leinwand LA. Identification of functional differences between recombinant human a and ? cardiac myosin motors. Cell Mol Life Sci. 2012 07; 69(13):2261-77.
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Armel TZ, Leinwand LA. A mutation in the beta-myosin rod associated with hypertrophic cardiomyopathy has an unexpected molecular phenotype. Biochem Biophys Res Commun. 2010 Jan 01; 391(1):352-6.
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Sivaramakrishnan S, Ashley E, Leinwand L, Spudich JA. Insights into human beta-cardiac myosin function from single molecule and single cell studies. J Cardiovasc Transl Res. 2009 Dec; 2(4):426-40.
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Hamady M, Buvoli M, Leinwand LA, Knight R. Estimate of the abundance of cardiomyopathic mutations in the ?-myosin gene. Int J Cardiol. 2010 Sep 24; 144(1):124-6.
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