 Deuterium
"Deuterium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.
| Descriptor ID |
D003903
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| MeSH Number(s) |
D01.268.406.500 D01.362.340.500 D01.496.289
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Deuterium".
Below are MeSH descriptors whose meaning is more specific than "Deuterium".
This graph shows the total number of publications written about "Deuterium" by people in this website by year, and whether "Deuterium" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 2 | 3 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 4 | 4 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 3 | 3 | | 2004 | 2 | 2 | 4 | | 2005 | 0 | 5 | 5 | | 2006 | 1 | 1 | 2 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 3 | 4 | | 2010 | 0 | 3 | 3 | | 2011 | 1 | 3 | 4 | | 2012 | 1 | 3 | 4 | | 2013 | 1 | 1 | 2 | | 2014 | 0 | 4 | 4 | | 2015 | 0 | 2 | 2 | | 2017 | 0 | 2 | 2 | | 2018 | 1 | 3 | 4 | | 2019 | 0 | 4 | 4 | | 2020 | 1 | 2 | 3 | | 2021 | 0 | 2 | 2 | | 2023 | 1 | 3 | 4 | | 2024 | 0 | 1 | 1 | | 2025 | 2 | 1 | 3 | | 2026 | 1 | 1 | 2 |
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Below are the most recent publications written about "Deuterium" by people in Profiles.
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Frazier B, Vanden Heuvel S, Yadav K, Fu B, Zimmermann SA, Fu R, Vander Zanden C, Ostrovsky D, Vugmeyster L. Hydration water dynamics in amyloid-ß aggregates using deuterium and oxygen-17 solid-state NMR spectroscopy. J Chem Phys. 2026 Sep 07; 165(9).
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Vugmeyster L, Ostrovsky D. Dynamics studies of side-chains and hydration shells in amyloid-ß fibrils using deuterium and oxygen-17 solid-state NMR. Methods Enzymol. 2026; 729:145-177.
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Vugmeyster L, Frazier B, Fu R, Ostrovsky D. Multi-mode water dynamics in hydration shells of villin headpiece subdomain protein in the solid state using deuterium and oxygen-17 NMR spectroscopy. J Chem Phys. 2025 Jul 14; 163(2).
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Alamillo L, Ng DCM, Currie J, Black A, Pandi B, Manda V, Pavelka J, Schaal P, Travers JG, McKinsey TA, Lam MPY, Lau E. Deuterium labeling enables proteome-wide turnover kinetics analysis in cell culture. Cell Rep Methods. 2025 Jul 21; 5(7):101104.
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Currie J, Ng DCM, Pandi B, Black A, Manda V, Durham C, Pavelka J, Lam MPY, Lau E. Improved Method to Determine Protein Turnover Rates with Heavy Water Labeling by Mass Isotopomer Ratio Selection. J Proteome Res. 2025 04 04; 24(4):1992-2005.
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Vugmeyster L, Ostrovsky D, Fu R. Carbon-detected deuterium solid-state NMR rotating frame relaxation measurements for protein methyl groups under magic angle spinning. Solid State Nucl Magn Reson. 2024 04; 130:101922.
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Kandel SE, Gracey EG, Lampe JN. Consideration of Nevirapine Analogs To Reduce Metabolically Linked Hepatotoxicity: A Cautionary Tale of the Deuteration Approach. Chem Res Toxicol. 2023 10 16; 36(10):1631-1642.
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Klontz E, Obi JO, Wang Y, Glendening G, Carr J, Tsibouris C, Buddula S, Nallar S, Soares AS, Beckett D, Redzic JS, Eisenmesser E, Palm C, Schmidt K, Scudder AH, Obiorah T, Essuman K, Milbrandt J, Diantonio A, Ray K, Snyder MLD, Deredge D, Snyder GA. The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations. J Biol Chem. 2023 11; 299(11):105290.
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Vugmeyster L, Rodgers A, Ostrovsky D, James McKnight C, Fu R. Deuteron off-resonance rotating frame relaxation for the characterization of slow motions in rotating and static solid-state proteins. J Magn Reson. 2023 07; 352:107493.
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Rodgers A, Sawaged M, Ostrovsky D, Vugmeyster L. Effect of Cross-Seeding of Wild-Type Amyloid-ß1-40 Peptides with Post-translationally Modified Fibrils on Internal Dynamics of the Fibrils Using Deuterium Solid-State NMR. J Phys Chem B. 2023 04 06; 127(13):2887-2899.
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