Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Kristi S Anseth

TitleDistinguished Professor
InstitutionUniversity of Colorado Boulder
DepartmentChemical & Biological Engin
Phone303/492-3147
    Other Positions
    TitleDistinguished Professor
    InstitutionUniversity of Colorado Boulder
    DepartmentBiology-MCD Instruction

    TitleAssoc Director-Faculty
    InstitutionUniversity of Colorado Boulder
    DepartmentBiofrontiers Institute


    Collapse Research 
    Collapse research activities and funding
    R01HL171197     (ANSETH, KRISTI S.)Jul 5, 2024 - Apr 30, 2028
    NIH
    Hydrogel matrices to study the role of inflammation and biological sex on aortic valve fibrocalcification
    Role: Principal Investigator
    R01DK120921     (ANSETH, KRISTI S.)Aug 1, 2019 - Apr 30, 2028
    NIH
    Photoresponsive materials to study matricellular signaling dynamics during crypt formation and fission
    Role: Principal Investigator
    R01HL132353     (ANSETH, KRISTI S.)Dec 15, 2016 - Nov 30, 2021
    NIH
    Hydrogels to Study Synergistic Effects of Signaling Factors and Matrix Mechanics on Valve Disease Progression
    Role: Principal Investigator
    R21AR067469     (ANSETH, KRISTI S.)Apr 1, 2015 - Mar 31, 2018
    NIH
    Mechanical Dosing Effects on MSCs
    Role: Principal Investigator
    R21EB018505     (ANSETH, KRISTI S.)Aug 15, 2014 - Jul 31, 2018
    NIH
    Protease Activity in 3D Matrices
    Role: Principal Investigator
    R21AR057904     (ANSETH, KRISTI S.)Jul 1, 2010 - Jun 30, 2013
    NIH
    Engineering Tissue with miRNAs
    Role: Principal Investigator
    R01CA132633     (ZAMAN, MUHAMMAD HAMID)Sep 1, 2008 - Jul 31, 2013
    NIH
    Quantitative Analysis of Tumor Cell Migration in Three Dimensioinal Matrices
    Role: Co-Principal Investigator
    R01HL089260     (ANSETH, KRISTI S.)Mar 1, 2008 - Feb 28, 2013
    NIH
    Bioactive Hydrogel Niches for 3D VIC Culture
    Role: Principal Investigator
    R01DK076084     (ANSETH, KRISTI S.)Jan 7, 2008 - Dec 31, 2013
    NIH
    Bioactive Gels that Promote Long-Term Islet Survival and Function
    Role: Principal Investigator
    R01AR053126     (ANSETH, KRISTI S.)Sep 25, 2005 - Jul 31, 2011
    NIH
    Online Monitoring and Control of Functional Cartilage Regeneration in Hydrogels
    Role: Principal Investigator
    R01DE016523     (ANSETH, KRISTI S.)May 1, 2005 - Feb 28, 2025
    NIH
    Clickable Microgel Scaffolds for MSC Expansion and Delivery
    Role: Principal Investigator
    R01DE012998     (ANSETH, KRISTI S.)Sep 1, 1998 - May 31, 2009
    NIH
    Photopolymerized Gels for Cartilage Tissue Engineering
    Role: Principal Investigator
    R29AR044375     (ANSETH, KRISTI S.)May 1, 1998 - Apr 30, 2004
    NIH
    NOVEL DEGRADABLE POLYMERS FOR ORTHOPEDIC APPLICATIONS
    Role: Principal Investigator
    R55AR044375     (ANSETH, KRISTI S.)Sep 30, 1997 - Apr 30, 1998
    NIH
    NOVEL DEGRADABLE POLYMERS FOR ORTHOPEDIC APPLICATIONS
    Role: Principal Investigator
    F32AR008387     (ANSETH, KRISTI S.)Apr 8, 1996
    NIH
    NOVEL DEGRADABLE POLYMERS FOR ORTHOPEDIC APPLICATIONS
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. McNally DL, Macdougall LJ, Kirkpatrick BE, Maduka CV, Hoffman TE, Fairbanks BD, Bowman CN, Spencer SL, Anseth KS. Reversible Intracellular Gelation of MCF10A Cells Enables Programmable Control Over 3D Spheroid Growth. Adv Healthc Mater. 2024 03; 13(7):e2302528. PMID: 38142299.
      View in: PubMed
    2. Nelson BR, Kirkpatrick BE, Skillin NP, Di Caprio N, Lee JS, Hibbard LP, Hach GK, Khang A, White TJ, Burdick JA, Bowman CN, Anseth KS. Facile Physicochemical Reprogramming of PEG-Dithiolane Microgels. Adv Healthc Mater. 2024 Oct; 13(25):e2302925. PMID: 37984810.
      View in: PubMed
    3. Beedle AEM, Jaganathan A, Albajar-Sigal?s A, Yavitt FM, Bera K, Andreu I, Granero-Moya I, Zalvidea D, Kechagia Z, Wiche G, Trepat X, Ivaska J, Anseth KS, Shenoy VB, Roca-Cusachs P. Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton. bioRxiv. 2023 Nov 11. PMID: 37986921.
      View in: PubMed
    4. Felisbino MB, Rubino M, Travers JG, Schuetze KB, Lemieux ME, Anseth KS, Aguado BA, McKinsey TA. Substrate stiffness modulates cardiac fibroblast activation, senescence, and proinflammatory secretory phenotype. Am J Physiol Heart Circ Physiol. 2024 01 01; 326(1):H61-H73. PMID: 37889253.
      View in: PubMed
    5. Desai S, Carberry BJ, Anseth KS, Schultz KM. Characterizing rheological properties and microstructure of thioester networks during degradation. Soft Matter. 2023 Oct 04; 19(38):7429-7442. PMID: 37743747.
      View in: PubMed
    6. Skillin NP, Kirkpatrick BE, Herbert KM, Nelson BR, Hach GK, G?nay KA, Khan RM, DelRio FW, White TJ, Anseth KS. Stiffness anisotropy coordinates supracellular contractility driving long-range myotube-ECM alignment. bioRxiv. 2023 Aug 11. PMID: 37609145.
      View in: PubMed
    7. G?nay KA, Chang TL, Skillin NP, Rao VV, Macdougall LJ, Cutler AA, Silver JS, Brown TE, Zhang C, Yu CJ, Olwin BB, Boyden ES, Anseth KS. Photo-expansion microscopy enables super-resolution imaging of cells embedded in 3D hydrogels. Nat Mater. 2023 06; 22(6):777-785. PMID: 37217701.
      View in: PubMed
    8. Blatchley MR, Anseth KS. Middle-out methods for spatiotemporal tissue engineering of organoids. Nat Rev Bioeng. 2023; 1(5):329-345. PMID: 37168734.
      View in: PubMed
    9. Nelson BR, Kirkpatrick BE, Miksch CE, Davidson MD, Skillin NP, Hach GK, Khang A, Hummel SN, Fairbanks BD, Burdick JA, Bowman CN, Anseth KS. Photoinduced Dithiolane Crosslinking for Multiresponsive Dynamic Hydrogels. Adv Mater. 2024 Oct; 36(43):e2211209. PMID: 36715698.
      View in: PubMed
    10. Mohagheghian E, Luo J, Yavitt FM, Wei F, Bhala P, Amar K, Rashid F, Wang Y, Liu X, Ji C, Chen J, Arnold DP, Liu Z, Anseth KS, Wang N. Quantifying stiffness and forces of tumor colonies and embryos using a magnetic microrobot. Sci Robot. 2023 01 25; 8(74):eadc9800. PMID: 36696474.
      View in: PubMed
    11. Yavitt FM, Kirkpatrick BE, Blatchley MR, Speckl KF, Mohagheghian E, Moldovan R, Wang N, Dempsey PJ, Anseth KS. In situ modulation of intestinal organoid epithelial curvature through photoinduced viscoelasticity directs crypt morphogenesis. Sci Adv. 2023 01 20; 9(3):eadd5668. PMID: 36662859.
      View in: PubMed
    12. Vogt BJ, Anseth KS, Aguado BA. Correction: Inflammatory serum factors from aortic valve stenosis patients modulate sex differences in valvular myofibroblast activation and osteoblast-like differentiation. Biomater Sci. 2022 Nov 08; 10(22):6627. PMID: 36281803.
      View in: PubMed
    13. Vogt BJ, Peters DK, Anseth KS, Aguado BA. Inflammatory serum factors from aortic valve stenosis patients modulate sex differences in valvular myofibroblast activation and osteoblast-like differentiation. Biomater Sci. 2022 Nov 08; 10(22):6341-6353. PMID: 36226463.
      View in: PubMed
    14. Walker CJ, Batan D, Bishop CT, Ramirez D, Aguado BA, Schroeder ME, Crocini C, Schwisow J, Moulton K, Macdougall L, Weiss RM, Allen MA, Dowell R, Leinwand LA, Anseth KS. Extracellular matrix stiffness controls cardiac valve myofibroblast activation through epigenetic remodeling. Bioeng Transl Med. 2022 Sep; 7(3):e10394. PMID: 36176599.
      View in: PubMed
    15. Hebner TS, Kirkpatrick BE, Anseth KS, Bowman CN, White TJ. Surface-Enforced Alignment of Reprogrammable Liquid Crystalline Elastomers. Adv Sci (Weinh). 2022 Oct; 9(29):e2204003. PMID: 35988144.
      View in: PubMed
    16. Macdougall LJ, Hoffman TE, Kirkpatrick BE, Fairbanks BD, Bowman CN, Spencer SL, Anseth KS. Intracellular Crowding by Bio-Orthogonal Hydrogel Formation Induces Reversible Molecular Stasis. Adv Mater. 2022 Aug; 34(31):e2202882. PMID: 35671709.
      View in: PubMed
    17. Miksch CE, Skillin NP, Kirkpatrick BE, Hach GK, Rao VV, White TJ, Anseth KS. 4D Printing of Extrudable and Degradable Poly(Ethylene Glycol) Microgel Scaffolds for Multidimensional Cell Culture. Small. 2022 09; 18(36):e2200951. PMID: 35732614.
      View in: PubMed
    18. Schroeder ME, Batan D, Gonzalez Rodriguez A, Speckl KF, Peters DK, Kirkpatrick BE, Hach GK, Walker CJ, Grim JC, Aguado BA, Weiss RM, Anseth KS. Osteopontin activity modulates sex-specific calcification in engineered valve tissue mimics. Bioeng Transl Med. 2023 Jan; 8(1):e10358. PMID: 36684107.
      View in: PubMed
    19. Borelli AN, Young MW, Kirkpatrick BE, Jaeschke MW, Mellett S, Porter S, Blatchley MR, Rao VV, Sridhar BV, Anseth KS. Stress Relaxation and Composition of Hydrazone-Crosslinked Hybrid Biopolymer-Synthetic Hydrogels Determine Spreading and Secretory Properties of MSCs. Adv Healthc Mater. 2022 07; 11(14):e2200393. PMID: 35575970.
      View in: PubMed
    20. Batan D, Peters DK, Schroeder ME, Aguado BA, Young MW, Weiss RM, Anseth KS. Hydrogel cultures reveal Transient Receptor Potential Vanilloid 4 regulation of myofibroblast activation and proliferation in valvular interstitial cells. FASEB J. 2022 05; 36(5):e22306. PMID: 35385164.
      View in: PubMed
    21. Rao VV, Wechsler ME, Cravens E, Wojda SJ, Caldwell AS, Kirkpatrick BE, Donahue SW, Anseth KS. Granular PEG hydrogels mediate osteoporotic MSC clustering via N-cadherin influencing the pro-resorptive bias of their secretory profile. Acta Biomater. 2022 06; 145:77-87. PMID: 35460910.
      View in: PubMed
    22. Qazi TH, Blatchley MR, Davidson MD, Yavitt FM, Cooke ME, Anseth KS, Burdick JA. Programming hydrogels to probe spatiotemporal cell biology. Cell Stem Cell. 2022 05 05; 29(5):678-691. PMID: 35413278.
      View in: PubMed
    23. Anseth KS, Xia Y. A Tribute to Professor Nicholas Peppas. Adv Healthc Mater. 2022 04; 11(7):e2200412. PMID: 35385227.
      View in: PubMed
    24. Yavitt FM, Kirkpatrick BE, Blatchley MR, Anseth KS. 4D Materials with Photoadaptable Properties Instruct and Enhance Intestinal Organoid Development. ACS Biomater Sci Eng. 2022 Nov 14; 8(11):4634-4638. PMID: 35298149.
      View in: PubMed
    25. Blatchley MR, G?nay KA, Yavitt FM, Hawat EM, Dempsey PJ, Anseth KS. In Situ Super-Resolution Imaging of Organoids and Extracellular Matrix Interactions via Phototransfer by Allyl Sulfide Exchange-Expansion Microscopy (PhASE-ExM). Adv Mater. 2022 Apr; 34(16):e2109252. PMID: 35182403.
      View in: PubMed
    26. Rogers JD, Aguado BA, Watts KM, Anseth KS, Richardson WJ. Network modeling predicts personalized gene expression and drug responses in valve myofibroblasts cultured with patient sera. Proc Natl Acad Sci U S A. 2022 02 22; 119(8). PMID: 35181609.
      View in: PubMed
    27. Aguado BA, Walker CJ, Grim JC, Schroeder ME, Batan D, Vogt BJ, Rodriguez AG, Schwisow JA, Moulton KS, Weiss RM, Heistad DD, Leinwand LA, Anseth KS. Genes That Escape X Chromosome Inactivation Modulate Sex Differences in Valve Myofibroblasts. Circulation. 2022 02 15; 145(7):513-530. PMID: 35000411.
      View in: PubMed
    28. Gjorevski N, Nikolaev M, Brown TE, Mitrofanova O, Brandenberg N, DelRio FW, Yavitt FM, Liberali P, Anseth KS, Lutolf MP. Tissue geometry drives deterministic organoid patterning. Science. 2022 Jan 07; 375(6576):eaaw9021. PMID: 34990240.
      View in: PubMed
    29. Walker CJ, Crocini C, Ramirez D, Killaars AR, Grim JC, Aguado BA, Clark K, Allen MA, Dowell RD, Leinwand LA, Anseth KS. Author Correction: Nuclear mechanosensing drives chromatin remodelling in persistently activated fibroblasts. Nat Biomed Eng. 2021 Dec; 5(12):1517-1518. PMID: 34050334.
      View in: PubMed
    30. Shin DS, Schroeder ME, Anseth KS. Impact of Collagen Triple Helix Structure on Melanoma Cell Invadopodia Formation and Matrix Degradation upon BRAF Inhibitor Treatment. Adv Healthc Mater. 2022 04; 11(7):e2101592. PMID: 34783464.
      View in: PubMed
    31. Carberry BJ, Hergert JE, Yavitt FM, Hernandez JJ, Speckl KF, Bowman CN, McLeod RR, Anseth KS. 3D printing of sacrificial thioester elastomers using digital light processing for templating 3D organoid structures in soft biomatrices. Biofabrication. 2021 09 02; 13(4). PMID: 34380115.
      View in: PubMed
    32. G?nay KA, Silver JS, Chang TL, Bednarski OJ, Bannister KL, Rogowski CJ, Olwin BB, Anseth KS. Myoblast mechanotransduction and myotube morphology is dependent on BAG3 regulation of YAP and TAZ. Biomaterials. 2021 10; 277:121097. PMID: 34481290.
      View in: PubMed
    33. Walker CJ, Schroeder ME, Aguado BA, Anseth KS, Leinwand LA. Matters of the heart: Cellular sex differences. J Mol Cell Cardiol. 2021 11; 160:42-55. PMID: 34166708.
      View in: PubMed
    34. Shin DS, Anseth KS. Recent advances in 3D models of tumor invasion. Curr Opin Biomed Eng. 2021 Sep; 19. PMID: 34308009.
      View in: PubMed
    35. Peter AK, Walker CJ, Ceccato T, Trexler CL, Ozeroff CD, Lugo KR, Perry AR, Anseth KS, Leinwand LA. Cardiac Fibroblasts Mediate a Sexually Dimorphic Fibrotic Response to ?-Adrenergic Stimulation. J Am Heart Assoc. 2021 06; 10(11):e018876. PMID: 33998248.
      View in: PubMed
    36. Walker CJ, Crocini C, Ramirez D, Killaars AR, Grim JC, Aguado BA, Clark K, Allen MA, Dowell RD, Leinwand LA, Anseth KS. Nuclear mechanosensing drives chromatin remodelling in persistently activated fibroblasts. Nat Biomed Eng. 2021 12; 5(12):1485-1499. PMID: 33875841.
      View in: PubMed
    37. Fairbanks BD, Macdougall LJ, Mavila S, Sinha J, Kirkpatrick BE, Anseth KS, Bowman CN. Photoclick Chemistry: A Bright Idea. Chem Rev. 2021 06 23; 121(12):6915-6990. PMID: 33835796.
      View in: PubMed
    38. Caldwell AS, Rao VV, Golden AC, Bell DJ, Grim JC, Anseth KS. Mesenchymal stem cell-inspired microgel scaffolds to control macrophage polarization. Bioeng Transl Med. 2021 May; 6(2):e10217. PMID: 34027099.
      View in: PubMed
    39. Richardson BM, Walker CJ, Maples MM, Randolph MA, Bryant SJ, Anseth KS. Mechanobiological Interactions between Dynamic Compressive Loading and Viscoelasticity on Chondrocytes in Hydrazone Covalent Adaptable Networks for Cartilage Tissue Engineering. Adv Healthc Mater. 2021 05; 10(9):e2002030. PMID: 33738966.
      View in: PubMed
    40. Silver JS, G?nay KA, Cutler AA, Vogler TO, Brown TE, Pawlikowski BT, Bednarski OJ, Bannister KL, Rogowski CJ, Mckay AG, DelRio FW, Olwin BB, Anseth KS. Injury-mediated stiffening persistently activates muscle stem cells through YAP and TAZ mechanotransduction. Sci Adv. 2021 03; 7(11). PMID: 33712460.
      View in: PubMed
    41. Gonzalez Rodriguez A, Schroeder ME, Grim JC, Walker CJ, Speckl KF, Weiss RM, Anseth KS. Tumor necrosis factor-a promotes and exacerbates calcification in heart valve myofibroblast populations. FASEB J. 2021 03; 35(3):e21382. PMID: 33554387.
      View in: PubMed
    42. Wechsler ME, Rao VV, Borelli AN, Anseth KS. Engineering the MSC Secretome: A Hydrogel Focused Approach. Adv Healthc Mater. 2021 04; 10(7):e2001948. PMID: 33594836.
      View in: PubMed
    43. Macdougall LJ, Wechsler ME, Culver HR, Benke EH, Broerman A, Bowman CN, Anseth KS. Charged Poly(N-isopropylacrylamide) Nanogels for the Stabilization of High Isoelectric Point Proteins. ACS Biomater Sci Eng. 2021 09 13; 7(9):4282-4292. PMID: 33560107.
      View in: PubMed
    44. Schroeder ME, Gonzalez Rodriguez A, Speckl KF, Walker CJ, Midekssa FS, Grim JC, Weiss RM, Anseth KS. Collagen networks within 3D PEG hydrogels support valvular interstitial cell matrix mineralization. Acta Biomater. 2021 01 01; 119:197-210. PMID: 33181362.
      View in: PubMed
    45. Grim JC, Aguado BA, Vogt BJ, Batan D, Andrichik CL, Schroeder ME, Gonzalez-Rodriguez A, Yavitt FM, Weiss RM, Anseth KS. Secreted Factors From Proinflammatory Macrophages Promote an Osteoblast-Like Phenotype in Valvular Interstitial Cells. Arterioscler Thromb Vasc Biol. 2020 11; 40(11):e296-e308. PMID: 32938214.
      View in: PubMed
    46. Ceccato TL, Starbuck RB, Hall JK, Walker CJ, Brown TE, Killgore JP, Anseth KS, Leinwand LA. Defining the Cardiac Fibroblast Secretome in a Fibrotic Microenvironment. J Am Heart Assoc. 2020 10 20; 9(19):e017025. PMID: 32924724.
      View in: PubMed
    47. Ma H, Macdougall LJ, GonzalezRodriguez A, Schroeder ME, Batan D, Weiss RM, Anseth KS. Calcium Signaling Regulates Valvular Interstitial Cell Alignment and Myofibroblast Activation in Fast-Relaxing Boronate Hydrogels. Macromol Biosci. 2020 12; 20(12):e2000268. PMID: 32924320.
      View in: PubMed
    48. Wojda SJ, Marozas IA, Anseth KS, Yaszemski MJ, Donahue SW. Impact of Release Kinetics on Efficacy of Locally Delivered Parathyroid Hormone for Bone Regeneration Applications. Tissue Eng Part A. 2021 02; 27(3-4):246-255. PMID: 32615861.
      View in: PubMed
    49. Killaars AR, Walker CJ, Anseth KS. Nuclear mechanosensing controls MSC osteogenic potential through HDAC epigenetic remodeling. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21258-21266. PMID: 32817542.
      View in: PubMed
    50. Richardson BM, Walker CJ, Macdougall LJ, Hoye JW, Randolph MA, Bryant SJ, Anseth KS. Viscoelasticity of hydrazone crosslinked poly(ethylene glycol) hydrogels directs chondrocyte morphology during mechanical deformation. Biomater Sci. 2020 Jul 21; 8(14):3804-3811. PMID: 32602512.
      View in: PubMed
    51. Yavitt FM, Brown TE, Hushka EA, Brown ME, Gjorevski N, Dempsey PJ, Lutolf MP, Anseth KS. The Effect of Thiol Structure on Allyl Sulfide Photodegradable Hydrogels and their Application as a Degradable Scaffold for Organoid Passaging. Adv Mater. 2020 Jul; 32(30):e1905366. PMID: 32548863.
      View in: PubMed
    52. Ma H, Caldwell AS, Azagarsamy MA, Gonzalez Rodriguez A, Anseth KS. Bioorthogonal click chemistries enable simultaneous spatial patterning of multiple proteins to probe synergistic protein effects on fibroblast function. Biomaterials. 2020 10; 255:120205. PMID: 32574845.
      View in: PubMed
    53. Carberry BJ, Rao VV, Anseth KS. Phototunable Viscoelasticity in Hydrogels Through Thioester Exchange. Ann Biomed Eng. 2020 Jul; 48(7):2053-2063. PMID: 32020346.
      View in: PubMed
    54. Hushka EA, Yavitt FM, Brown TE, Dempsey PJ, Anseth KS. Relaxation of Extracellular Matrix Forces Directs Crypt Formation and Architecture in Intestinal Organoids. Adv Healthc Mater. 2020 04; 9(8):e1901214. PMID: 31957249.
      View in: PubMed
    55. Caldwell AS, Rao VV, Golden AC, Anseth KS. Porous bio-click microgel scaffolds control hMSC interactions and promote their secretory properties. Biomaterials. 2020 02; 232:119725. PMID: 31918222.
      View in: PubMed
    56. Caldwell AS, Aguado BA, Anseth KS. Designing Microgels for Cell Culture and Controlled Assembly of Tissue Microenvironments. Adv Funct Mater. 2020 Sep 10; 30(37). PMID: 33841061.
      View in: PubMed
    57. Wojda SJ, Marozas IA, Anseth KS, Yaszemski MJ, Donahue SW. Thiol-ene Hydrogels for Local Delivery of PTH for Bone Regeneration in Critical Size defects. J Orthop Res. 2020 03; 38(3):536-544. PMID: 31709588.
      View in: PubMed
    58. Aguado BA, Schuetze KB, Grim JC, Walker CJ, Cox AC, Ceccato TL, Tan AC, Sucharov CC, Leinwand LA, Taylor MRG, McKinsey TA, Anseth KS. Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation. Sci Transl Med. 2019 09 11; 11(509). PMID: 31511425.
      View in: PubMed
    59. Marozas IA, Anseth KS, Cooper-White JJ. Adaptable boronate ester hydrogels with tunable viscoelastic spectra to probe timescale dependent mechanotransduction. Biomaterials. 2019 12; 223:119430. PMID: 31493696.
      View in: PubMed
    60. Khang A, Gonzalez Rodriguez A, Schroeder ME, Sansom J, Lejeune E, Anseth KS, Sacks MS. Quantifying heart valve interstitial cell contractile state using highly tunable poly(ethylene glycol) hydrogels. Acta Biomater. 2019 09 15; 96:354-367. PMID: 31323351.
      View in: PubMed
    61. G?nay KA, Ceccato TL, Silver JS, Bannister KL, Bednarski OJ, Leinwand LA, Anseth KS. PEG-Anthracene Hydrogels as an On-Demand Stiffening Matrix To Study Mechanobiology. Angew Chem Int Ed Engl. 2019 07 15; 58(29):9912-9916. PMID: 31119851.
      View in: PubMed
    62. Crocini C, Walker CJ, Anseth KS, Leinwand LA. Three-dimensional encapsulation of adult mouse cardiomyocytes in hydrogels with tunable stiffness. Prog Biophys Mol Biol. 2020 08; 154:71-79. PMID: 31122749.
      View in: PubMed
    63. Pe?a B, Maldonado M, Bonham AJ, Aguado BA, Dominguez-Alfaro A, Laughter M, Rowland TJ, Bardill J, Farnsworth NL, Alegret Ramon N, Taylor MRG, Anseth KS, Prato M, Shandas R, McKinsey TA, Park D, Mestroni L. Gold Nanoparticle-Functionalized Reverse Thermal Gel for Tissue Engineering Applications. ACS Appl Mater Interfaces. 2019 May 22; 11(20):18671-18680. PMID: 31021594.
      View in: PubMed
    64. Killaars AR, Grim JC, Walker CJ, Hushka EA, Brown TE, Anseth KS. Extended Exposure to Stiff Microenvironments Leads to Persistent Chromatin Remodeling in Human Mesenchymal Stem Cells. Adv Sci (Weinh). 2019 Feb 06; 6(3):1801483. PMID: 30775233.
      View in: PubMed
    65. Gonzalez Rodriguez A, Schroeder ME, Walker CJ, Anseth KS. FGF-2 inhibits contractile properties of valvular interstitial cell myofibroblasts encapsulated in 3D MMP-degradable hydrogels. APL Bioeng. 2018 Dec; 2(4):046104. PMID: 31069326.
      View in: PubMed
    66. LeValley PJ, Tibbitt MW, Noren B, Kharkar P, Kloxin AM, Anseth KS, Toner M, Oakey J. Immunofunctional photodegradable poly(ethylene glycol) hydrogel surfaces for the capture and release of rare cells. Colloids Surf B Biointerfaces. 2019 Feb 01; 174:483-492. PMID: 30497010.
      View in: PubMed
    67. Richardson BM, Wilcox DG, Randolph MA, Anseth KS. Hydrazone covalent adaptable networks modulate extracellular matrix deposition for cartilage tissue engineering. Acta Biomater. 2019 01 01; 83:71-82. PMID: 30419278.
      View in: PubMed
    68. Rao VV, Vu MK, Ma H, Killaars AR, Anseth KS. Rescuing mesenchymal stem cell regenerative properties on hydrogel substrates post serial expansion. Bioeng Transl Med. 2019 Jan; 4(1):51-60. PMID: 30680318.
      View in: PubMed
    69. Brown TE, Silver JS, Worrell BT, Marozas IA, Yavitt FM, G?nay KA, Bowman CN, Anseth KS. Secondary Photocrosslinking of Click Hydrogels To Probe Myoblast Mechanotransduction in Three Dimensions. J Am Chem Soc. 2018 09 19; 140(37):11585-11588. PMID: 30183266.
      View in: PubMed
    70. Deming TJ, Klok HA, Armes SP, Becker ML, Champion JA, Chen EY, Heilshorn SC, van Hest JCM, Irvine DJ, Johnson JA, Kiessling LL, Maynard HD, de la Cruz MO, Sullivan MO, Tirrell MV, Anseth KS, Lecommandoux S, Percec S, Zhong Z, Albertsson AC. Polymers at the Interface with Biology. Biomacromolecules. 2018 08 13; 19(8):3151-3162. PMID: 30099879.
      View in: PubMed
    71. Tang S, Ma H, Tu HC, Wang HR, Lin PC, Anseth KS. Adaptable Fast Relaxing Boronate-Based Hydrogels for Probing Cell-Matrix Interactions. Adv Sci (Weinh). 2018 Sep; 5(9):1800638. PMID: 30250802.
      View in: PubMed
    72. Grim JC, Brown TE, Aguado BA, Chapnick DA, Viert AL, Liu X, Anseth KS. A Reversible and Repeatable Thiol-Ene Bioconjugation for Dynamic Patterning of Signaling Proteins in Hydrogels. ACS Cent Sci. 2018 Jul 25; 4(7):909-916. PMID: 30062120.
      View in: PubMed
    73. Brown TE, Carberry BJ, Worrell BT, Dudaryeva OY, McBride MK, Bowman CN, Anseth KS. Photopolymerized dynamic hydrogels with tunable viscoelastic properties through thioester exchange. Biomaterials. 2018 09; 178:496-503. PMID: 29653871.
      View in: PubMed
    74. Rosales AM, Rodell CB, Chen MH, Morrow MG, Anseth KS, Burdick JA. Reversible Control of Network Properties in Azobenzene-Containing Hyaluronic Acid-Based Hydrogels. Bioconjug Chem. 2018 04 18; 29(4):905-913. PMID: 29406696.
      View in: PubMed
    75. Sridhar BV, Janczy JR, Hatlevik ?, Wolfson G, Anseth KS, Tibbitt MW. Thermal Stabilization of Biologics with Photoresponsive Hydrogels. Biomacromolecules. 2018 03 12; 19(3):740-747. PMID: 29394044.
      View in: PubMed
    76. Aguado BA, Grim JC, Rosales AM, Watson-Capps JJ, Anseth KS. Engineering precision biomaterials for personalized medicine. Sci Transl Med. 2018 01 17; 10(424). PMID: 29343626.
      View in: PubMed
    77. Lewis KJR, Hall JK, Kiyotake EA, Christensen T, Balasubramaniam V, Anseth KS. Epithelial-mesenchymal crosstalk influences cellular behavior in a 3D alveolus-fibroblast model system. Biomaterials. 2018 Feb; 155:124-134. PMID: 29175081.
      View in: PubMed
    78. Brown TE, Anseth KS. Spatiotemporal hydrogel biomaterials for regenerative medicine. Chem Soc Rev. 2017 Oct 30; 46(21):6532-6552. PMID: 28820527.
      View in: PubMed
    79. Hodgson SM, McNelles SA, Abdullahu L, Marozas IA, Anseth KS, Adronov A. Reproducible Dendronized PEG Hydrogels via SPAAC Cross-Linking. Biomacromolecules. 2017 Dec 11; 18(12):4054-4059. PMID: 28968079.
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    80. Pe?a B, Bosi S, Aguado BA, Borin D, Farnsworth NL, Dobrinskikh E, Rowland TJ, Martinelli V, Jeong M, Taylor MRG, Long CS, Shandas R, Sbaizero O, Prato M, Anseth KS, Park D, Mestroni L. Injectable Carbon Nanotube-Functionalized Reverse Thermal Gel Promotes Cardiomyocytes Survival and Maturation. ACS Appl Mater Interfaces. 2017 Sep 20; 9(37):31645-31656. PMID: 28895403.
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    81. Rosales AM, Vega SL, DelRio FW, Burdick JA, Anseth KS. Hydrogels with Reversible Mechanics to Probe Dynamic Cell Microenvironments. Angew Chem Int Ed Engl. 2017 09 25; 56(40):12132-12136. PMID: 28799225.
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    82. Caldwell AS, Campbell GT, Shekiro KMT, Anseth KS. Clickable Microgel Scaffolds as Platforms for 3D Cell Encapsulation. Adv Healthc Mater. 2017 Aug; 6(15). PMID: 28485127.
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    83. Ma H, Killaars AR, DelRio FW, Yang C, Anseth KS. Myofibroblastic activation of valvular interstitial cells is modulated by spatial variations in matrix elasticity and its organization. Biomaterials. 2017 07; 131:131-144. PMID: 28390245.
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    84. Shin DS, Tokuda EY, Leight JL, Miksch CE, Brown TE, Anseth KS. Synthesis of microgel sensors for spatial and temporal monitoring of protease activity. ACS Biomater Sci Eng. 2018; 4(2):378-387. PMID: 29527570.
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    85. van Hest J, Sumerlin B, Anseth KS, Shoichet M, Hammes-Schiffer S. Editorial for Virtual Issue on Polymer Bioconjugates in Biology and Medicine. ACS Macro Lett. 2017 Feb 21; 6(2):144. PMID: 35632892.
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    86. van Hest J, Sumerlin B, Anseth KS, Shoichet M, Hammes-Schiffer S. Editorial for Virtual Issue on Polymer Bioconjugates in Biology and Medicine. Bioconjug Chem. 2017 02 15; 28(2):282. PMID: 28196420.
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    87. van Hest J, Sumerlin B, Anseth KS, Shoichet M, Hammes-Schiffer S. Editorial for Virtual Issue on Polymer Bioconjugates in Biology and Medicine. Biomacromolecules. 2017 02 13; 18(2):315. PMID: 28190348.
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    88. van Hest J, Sumerlin B, Anseth KS, Shoichet M, Hammes-Schiffer S. Editorial for Virtual Issue on Polymer Bioconjugates in Biology and Medicine. Chem Rev. 2017 02 08; 117(3):900. PMID: 28173700.
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    89. Tokuda EY, Jones CE, Anseth KS. PEG-peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity. Integr Biol (Camb). 2017 01 23; 9(1):76-87. PMID: 28001152.
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    90. Brown TE, Marozas IA, Anseth KS. Amplified Photodegradation of Cell-Laden Hydrogels via an Addition-Fragmentation Chain Transfer Reaction. Adv Mater. 2017 Mar; 29(11). PMID: 28112845.
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    91. Yang C, DelRio FW, Ma H, Killaars AR, Basta LP, Kyburz KA, Anseth KS. Spatially patterned matrix elasticity directs stem cell fate. Proc Natl Acad Sci U S A. 2016 08 02; 113(31):E4439-45. PMID: 27436901.
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    92. Zhao X, Papadopoulos A, Ibusuki S, Bichara DA, Saris DB, Malda J, Anseth KS, Gill TJ, Randolph MA. Articular cartilage generation applying PEG-LA-DM/PEGDM copolymer hydrogels. BMC Musculoskelet Disord. 2016 06 03; 17:245. PMID: 27255078.
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    93. Mabry KM, Schroeder ME, Payne SZ, Anseth KS. Three-Dimensional High-Throughput Cell Encapsulation Platform to Study Changes in Cell-Matrix Interactions. ACS Appl Mater Interfaces. 2016 08 31; 8(34):21914-22. PMID: 27050338.
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    94. Magin CM, Alge DL, Anseth KS. Bio-inspired 3D microenvironments: a new dimension in tissue engineering. Biomed Mater. 2016 Mar 04; 11(2):022001. PMID: 26942469.
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    95. Rosales AM, Anseth KS. The design of reversible hydrogels to capture extracellular matrix dynamics. Nat Rev Mater. 2016; 1. PMID: 29214058.
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    96. Nehls EM, Rosales AM, Anseth KS. Enhanced User-Control of Small Molecule Drug Release from a Poly(ethylene glycol) Hydrogel via Azobenzene/Cyclodextrin Complex Tethers. J Mater Chem B. 2016; 4(6):1035-1039. PMID: 27127630.
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    97. Anseth KS, Klok HA. Click Chemistry in Biomaterials, Nanomedicine, and Drug Delivery. Biomacromolecules. 2016 Jan 11; 17(1):1-3. PMID: 26750314.
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    98. Azagarsamy MA, Marozas IA, Spaans S, Anseth KS. Photoregulated Hydrazone-Based Hydrogel Formation for Biochemically Patterning 3D Cellular Microenvironments. ACS Macro Lett. 2016 Jan 19; 5(1):19-23. PMID: 35668597.
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    99. Singh SP, Schwartz MP, Tokuda EY, Luo Y, Rogers RE, Fujita M, Ahn NG, Anseth KS. A synthetic modular approach for modeling the role of the 3D microenvironment in tumor progression. Sci Rep. 2015 Dec 07; 5:17814. PMID: 26638791.
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    100. Sridhar BV, Dailing EA, Brock JL, Stansbury JW, Randolph MA, Anseth KS. A Biosynthetic Scaffold that Facilitates Chondrocyte-Mediated Degradation and Promotes Articular Cartilage Extracellular Matrix Deposition. Regen Eng Transl Med. 2015 Dec; 1(1-4):11-21. PMID: 26900597.
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    101. Dailing EA, Nair DP, Setterberg WK, Kyburz KA, Yang C, D'Ovidio T, Anseth KS, Stansbury JW. Combined, Independent Small Molecule Release and Shape Memory via Nanogel-Coated Thiourethane Polymer Networks. Polym Chem. 2016 Jan 28; 7(4):816-825. PMID: 27066114.
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    102. Tibbitt MW, Rodell CB, Burdick JA, Anseth KS. Progress in material design for biomedical applications. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):14444-51. PMID: 26598696.
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    103. Mabry KM, Payne SZ, Anseth KS. Transcriptional profiles of valvular interstitial cells cultured on tissue culture polystyrene, on 2D hydrogels, or within 3D hydrogels. Data Brief. 2015 Dec; 5:959-62. PMID: 26702427.
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    104. Mabry KM, Payne SZ, Anseth KS. Microarray analyses to quantify advantages of 2D and 3D hydrogel culture systems in maintaining the native valvular interstitial cell phenotype. Biomaterials. 2016 Jan; 74:31-41. PMID: 26433490.
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    105. Grim JC, Marozas IA, Anseth KS. Thiol-ene and photo-cleavage chemistry for controlled presentation of biomolecules in hydrogels. J Control Release. 2015 Dec 10; 219:95-106. PMID: 26315818.
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    106. Schultz KM, Kyburz KA, Anseth KS. Measuring dynamic cell-material interactions and remodeling during 3D human mesenchymal stem cell migration in hydrogels. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):E3757-64. PMID: 26150508.
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    107. Leight JL, Tokuda EY, Jones CE, Lin AJ, Anseth KS. Multifunctional bioscaffolds for 3D culture of melanoma cells reveal increased MMP activity and migration with BRAF kinase inhibition. Proc Natl Acad Sci U S A. 2015 Apr 28; 112(17):5366-71. PMID: 25870264.
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    108. Lewis KJ, Tibbitt MW, Zhao Y, Branchfield K, Sun X, Balasubramaniam V, Anseth KS. In vitro model alveoli from photodegradable microsphere templates. Biomater Sci. 2015 Jun; 3(6):821-32. PMID: 26221842.
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    109. Kyburz KA, Anseth KS. Synthetic mimics of the extracellular matrix: how simple is complex enough? Ann Biomed Eng. 2015 Mar; 43(3):489-500. PMID: 25753017.
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    110. Mabry KM, Lawrence RL, Anseth KS. Dynamic stiffening of poly(ethylene glycol)-based hydrogels to direct valvular interstitial cell phenotype in a three-dimensional environment. Biomaterials. 2015 May; 49:47-56. PMID: 25725554.
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    111. Rosales AM, Mabry KM, Nehls EM, Anseth KS. Photoresponsive elastic properties of azobenzene-containing poly(ethylene-glycol)-based hydrogels. Biomacromolecules. 2015 Mar 09; 16(3):798-806. PMID: 25629423.
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    112. Sridhar BV, Brock JL, Silver JS, Leight JL, Randolph MA, Anseth KS. Development of a cellularly degradable PEG hydrogel to promote articular cartilage extracellular matrix deposition. Adv Healthc Mater. 2015 Apr 02; 4(5):702-13. PMID: 25607633.
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    113. McKinnon DD, Domaille DW, Brown TE, Kyburz KA, Kiyotake E, Cha JN, Anseth KS. Measuring cellular forces using bis-aliphatic hydrazone crosslinked stress-relaxing hydrogels. Soft Matter. 2014 Dec 14; 10(46):9230-6. PMID: 25265090.
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    114. Wang H, Leinwand LA, Anseth KS. Cardiac valve cells and their microenvironment--insights from in vitro studies. Nat Rev Cardiol. 2014 Dec; 11(12):715-27. PMID: 25311230.
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    115. Wang H, Leinwand LA, Anseth KS. Roles of transforming growth factor-?1 and OB-cadherin in porcine cardiac valve myofibroblast differentiation. FASEB J. 2014 Oct; 28(10):4551-62. PMID: 25008089.
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    116. Singh SP, Schwartz MP, Lee JY, Fairbanks BD, Anseth KS. A peptide functionalized poly(ethylene glycol) (PEG) hydrogel for investigating the influence of biochemical and biophysical matrix properties on tumor cell migration. Biomater Sci. 2014 Jul 01; 2(7):1024-1034. PMID: 25105013.
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    117. McKinnon DD, Brown TE, Kyburz KA, Kiyotake E, Anseth KS. Design and characterization of a synthetically accessible, photodegradable hydrogel for user-directed formation of neural networks. Biomacromolecules. 2014 Jul 14; 15(7):2808-16. PMID: 24932668.
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    118. Azagarsamy MA, McKinnon DD, Alge DL, Anseth KS. Coumarin-Based Photodegradable Hydrogel: Design, Synthesis, Gelation, and Degradation Kinetics. ACS Macro Lett. 2014 Jun 17; 3(6):515-519. PMID: 35590721.
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    119. Yang C, Tibbitt MW, Basta L, Anseth KS. Mechanical memory and dosing influence stem cell fate. Nat Mater. 2014 Jun; 13(6):645-52. PMID: 24633344.
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    120. El Accaoui RN, Gould ST, Hajj GP, Chu Y, Davis MK, Kraft DC, Lund DD, Brooks RM, Doshi H, Zimmerman KA, Kutschke W, Anseth KS, Heistad DD, Weiss RM. Aortic valve sclerosis in mice deficient in endothelial nitric oxide synthase. Am J Physiol Heart Circ Physiol. 2014 May; 306(9):H1302-13. PMID: 24610917.
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    121. Gandavarapu NR, Alge DL, Anseth KS. Osteogenic differentiation of human mesenchymal stem cells on a5 integrin binding peptide hydrogels is dependent on substrate elasticity. Biomater Sci. 2014 Mar 01; 2(3):352-361. PMID: 24660057.
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    122. Sridhar BV, Doyle NR, Randolph MA, Anseth KS. Covalently tethered TGF-?1 with encapsulated chondrocytes in a PEG hydrogel system enhances extracellular matrix production. J Biomed Mater Res A. 2014 Dec; 102(12):4464-72. PMID: 24616326.
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    123. Tokuda EY, Leight JL, Anseth KS. Modulation of matrix elasticity with PEG hydrogels to study melanoma drug responsiveness. Biomaterials. 2014 May; 35(14):4310-8. PMID: 24565518.
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    124. Gandavarapu NR, Azagarsamy MA, Anseth KS. Photo-click living strategy for controlled, reversible exchange of biochemical ligands. Adv Mater. 2014 Apr 23; 26(16):2521-6. PMID: 24523204.
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    125. Gould ST, Matherly EE, Smith JN, Heistad DD, Anseth KS. The role of valvular endothelial cell paracrine signaling and matrix elasticity on valvular interstitial cell activation. Biomaterials. 2014 Apr; 35(11):3596-606. PMID: 24462357.
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    126. Kirschner CM, Alge DL, Gould ST, Anseth KS. Clickable, photodegradable hydrogels to dynamically modulate valvular interstitial cell phenotype. Adv Healthc Mater. 2014 May; 3(5):649-57. PMID: 24459068.
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    127. Hraha TH, Bernard AB, Nguyen LM, Anseth KS, Benninger RK. Dimensionality and size scaling of coordinated Ca(2+) dynamics in MIN6 ?-cell clusters. Biophys J. 2014 Jan 07; 106(1):299-309. PMID: 24411262.
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    129. Bernard AB, Chapman RZ, Anseth KS. Controlled local presentation of matrix proteins in microparticle-laden cell aggregates. Biotechnol Bioeng. 2014 May; 111(5):1028-37. PMID: 24255014.
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    130. Schwartz MP, Rogers RE, Singh SP, Lee JY, Loveland SG, Koepsel JT, Witze ES, Montanez-Sauri SI, Sung KE, Tokuda EY, Sharma Y, Everhart LM, Nguyen EH, Zaman MH, Beebe DJ, Ahn NG, Murphy WL, Anseth KS. A quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotype. PLoS One. 2013; 8(12):e81689. PMID: 24349113.
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    131. Wang H, Tibbitt MW, Langer SJ, Leinwand LA, Anseth KS. Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19336-41. PMID: 24218588.
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    132. Alge DL, Anseth KS. Bioactive hydrogels: Lighting the way. Nat Mater. 2013 Nov; 12(11):950-2. PMID: 24150411.
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    135. McKinnon DD, Domaille DW, Cha JN, Anseth KS. Biophysically defined and cytocompatible covalently adaptable networks as viscoelastic 3D cell culture systems. Adv Mater. 2014 Feb 12; 26(6):865-72. PMID: 24127293.
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    136. Alge DL, Donohue DF, Anseth KS. Facile and efficient Lewis acid catalyzed synthesis of an asymmetric tetrazine useful for bio-orthogonal click chemistry applications. Tetrahedron Lett. 2013 Oct 09; 54(41). PMID: 24270730.
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    137. Witze ES, Connacher MK, Houel S, Schwartz MP, Morphew MK, Reid L, Sacks DB, Anseth KS, Ahn NG. Wnt5a directs polarized calcium gradients by recruiting cortical endoplasmic reticulum to the cell trailing edge. Dev Cell. 2013 Sep 30; 26(6):645-57. PMID: 24091015.
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    138. Wang H, Sridhar B, Leinwand LA, Anseth KS. Characterization of cell subpopulations expressing progenitor cell markers in porcine cardiac valves. PLoS One. 2013; 8(7):e69667. PMID: 23936071.
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    139. Gould ST, Srigunapalan S, Simmons CA, Anseth KS. Hemodynamic and cellular response feedback in calcific aortic valve disease. Circ Res. 2013 Jul 05; 113(2):186-97. PMID: 23833293.
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    140. Leight JL, Alge DL, Maier AJ, Anseth KS. Direct measurement of matrix metalloproteinase activity in 3D cellular microenvironments using a fluorogenic peptide substrate. Biomaterials. 2013 Oct; 34(30):7344-52. PMID: 23830581.
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    141. Tibbitt MW, Kloxin AM, Anseth KS. Modeling Controlled Photodegradation in Optically Thick Hydrogels. J Polym Sci A Polym Chem. 2013 May 01; 51(9):1899-1911. PMID: 24496479.
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    142. Ruan JL, Tulloch NL, Muskheli V, Genova EE, Mariner PD, Anseth KS, Murry CE. An improved cryosection method for polyethylene glycol hydrogels used in tissue engineering. Tissue Eng Part C Methods. 2013 Oct; 19(10):794-801. PMID: 23448137.
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    143. Tibbitt MW, Kloxin AM, Sawicki L, Anseth KS. Mechanical Properties and Degradation of Chain and Step Polymerized Photodegradable Hydrogels. Macromolecules. 2013 Apr 09; 46(7). PMID: 24496435.
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    144. Alge DL, Azagarsamy MA, Donohue DF, Anseth KS. Synthetically tractable click hydrogels for three-dimensional cell culture formed using tetrazine-norbornene chemistry. Biomacromolecules. 2013 Apr 08; 14(4):949-53. PMID: 23448682.
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    145. Koehler KC, Alge DL, Anseth KS, Bowman CN. A Diels-Alder modulated approach to control and sustain the release of dexamethasone and induce osteogenic differentiation of human mesenchymal stem cells. Biomaterials. 2013 May; 34(16):4150-4158. PMID: 23465826.
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    146. Lewis KJ, Anseth KS. Hydrogel scaffolds to study cell biology in four dimensions. MRS Bull. 2013 Mar 01; 38(3):260-268. PMID: 25221384.
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    147. Shenoy R, Tibbitt MW, Anseth KS, Bowman CN. Formation of Core-Shell Particles by Interfacial Radical Polymerization Initiated by a Glucose Oxidase-Mediated Redox System. Chem Mater. 2013 Mar 12; 25(5):761-767. PMID: 23503321.
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    148. Kirschner CM, Anseth KS. Hydrogels in Healthcare: From Static to Dynamic Material Microenvironments. Acta Mater. 2013 Feb 01; 61(3):931-944. PMID: 23929381.
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    149. Kyburz KA, Anseth KS. Three-dimensional hMSC motility within peptide-functionalized PEG-based hydrogels of varying adhesivity and crosslinking density. Acta Biomater. 2013 May; 9(5):6381-92. PMID: 23376239.
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    150. Koehler KC, Anseth KS, Bowman CN. Diels-Alder mediated controlled release from a poly(ethylene glycol) based hydrogel. Biomacromolecules. 2013 Feb 11; 14(2):538-47. PMID: 23311608.
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    151. McKinnon DD, Kloxin AM, Anseth KS. Synthetic hydrogel platform for three-dimensional culture of embryonic stem cell-derived motor neurons. Biomater Sci. 2013 May 02; 1(5):460-469. PMID: 32482009.
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    152. Azagarsamy MA, Anseth KS. Bioorthogonal Click Chemistry: An Indispensable Tool to Create Multifaceted Cell Culture Scaffolds. ACS Macro Lett. 2013 Jan 15; 2(1):5-9. PMID: 23336091.
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    153. Kloxin AM, Lewis KJ, DeForest CA, Seedorf G, Tibbitt MW, Balasubramaniam V, Anseth KS. Responsive culture platform to examine the influence of microenvironmental geometry on cell function in 3D. Integr Biol (Camb). 2012 Dec; 4(12):1540-9. PMID: 23138879.
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    154. Tibbitt MW, Anseth KS. Dynamic microenvironments: the fourth dimension. Sci Transl Med. 2012 Nov 14; 4(160):160ps24. PMID: 23152326.
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    155. Adzima BJ, Kloxin CJ, DeForest CA, Anseth KS, Bowman CN. 3D Photofixation Lithography in Diels-Alder Networks. Macromol Rapid Commun. 2012 Dec 21; 33(24):2092-6. PMID: 23080017.
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    156. Kirschner CM, Anseth KS. In situ control of cell substrate microtopographies using photolabile hydrogels. Small. 2013 Feb 25; 9(4):578-84. PMID: 23074095.
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    157. Mariner PD, Wudel JM, Miller DE, Genova EE, Streubel SO, Anseth KS. Synthetic hydrogel scaffold is an effective vehicle for delivery of INFUSE (rhBMP2) to critical-sized calvaria bone defects in rats. J Orthop Res. 2013 Mar; 31(3):401-6. PMID: 23070779.
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    158. McCall JD, Luoma JE, Anseth KS. Covalently tethered transforming growth factor beta in PEG hydrogels promotes chondrogenic differentiation of encapsulated human mesenchymal stem cells. Drug Deliv Transl Res. 2012 Oct; 2(5):305-12. PMID: 23019539.
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    159. Gandavarapu NR, Mariner PD, Schwartz MP, Anseth KS. Extracellular matrix protein adsorption to phosphate-functionalized gels from serum promotes osteogenic differentiation of human mesenchymal stem cells. Acta Biomater. 2013 Jan; 9(1):4525-34. PMID: 22982322.
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    160. Guo Q, Wang X, Tibbitt MW, Anseth KS, Montell DJ, Elisseeff JH. Light activated cell migration in synthetic extracellular matrices. Biomaterials. 2012 Nov; 33(32):8040-6. PMID: 22889487.
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    161. Yang C, Mariner PD, Nahreini JN, Anseth KS. Cell-mediated delivery of glucocorticoids from thiol-ene hydrogels. J Control Release. 2012 Sep 28; 162(3):612-8. PMID: 22902591.
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    162. McCall JD, Anseth KS. Thiol-ene photopolymerizations provide a facile method to encapsulate proteins and maintain their bioactivity. Biomacromolecules. 2012 Aug 13; 13(8):2410-7. PMID: 22741550.
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    163. Wang H, Haeger SM, Kloxin AM, Leinwand LA, Anseth KS. Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus. PLoS One. 2012; 7(7):e39969. PMID: 22808079.
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    164. Azagarsamy MA, Alge DL, Radhakrishnan SJ, Tibbitt MW, Anseth KS. Photocontrolled nanoparticles for on-demand release of proteins. Biomacromolecules. 2012 Aug 13; 13(8):2219-24. PMID: 22746981.
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    165. Gould ST, Darling NJ, Anseth KS. Small peptide functionalized thiol-ene hydrogels as culture substrates for understanding valvular interstitial cell activation and de novo tissue deposition. Acta Biomater. 2012 Sep; 8(9):3201-9. PMID: 22609448.
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    166. Pedron S, Peinado C, Catalina F, Bosch P, Anseth KS, Abrusci C. Combinatorial approach for fabrication of coatings to control bacterial adhesion. J Biomater Sci Polym Ed. 2012; 23(12):1613-28. PMID: 21888758.
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    167. DeForest CA, Anseth KS. Advances in bioactive hydrogels to probe and direct cell fate. Annu Rev Chem Biomol Eng. 2012; 3:421-44. PMID: 22524507.
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    168. Tibbitt MW, Han BW, Kloxin AM, Anseth KS. Student award for outstanding research winner in the Ph.D. category for the 9th World Biomaterials Congress, Chengdu, China, June 1-5, 2012: synthesis and application of photodegradable microspheres for spatiotemporal control of protein delivery. J Biomed Mater Res A. 2012 Jul; 100(7):1647-54. PMID: 22447635.
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    169. Bernard AB, Lin CC, Anseth KS. A microwell cell culture platform for the aggregation of pancreatic ?-cells. Tissue Eng Part C Methods. 2012 Aug; 18(8):583-92. PMID: 22320435.
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    170. Hume PS, He J, Haskins K, Anseth KS. Strategies to reduce dendritic cell activation through functional biomaterial design. Biomaterials. 2012 May; 33(14):3615-25. PMID: 22361099.
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    171. DeForest CA, Anseth KS. Photoreversible patterning of biomolecules within click-based hydrogels. Angew Chem Int Ed Engl. 2012 Feb 20; 51(8):1816-9. PMID: 22162285.
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    172. DeForest CA, Anseth KS. Cytocompatible click-based hydrogels with dynamically tunable properties through orthogonal photoconjugation and photocleavage reactions. Nat Chem. 2011 Oct 23; 3(12):925-31. PMID: 22109271.
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    173. Hume PS, Anseth KS. Polymerizable superoxide dismutase mimetic protects cells encapsulated in poly(ethylene glycol) hydrogels from reactive oxygen species-mediated damage. J Biomed Mater Res A. 2011 Oct; 99(1):29-37. PMID: 21793194.
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    174. Mariner PD, Johannesen E, Anseth KS. Manipulation of miRNA activity accelerates osteogenic differentiation of hMSCs in engineered 3D scaffolds. J Tissue Eng Regen Med. 2012 Apr; 6(4):314-24. PMID: 21706778.
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    175. Hume PS, Bowman CN, Anseth KS. Functionalized PEG hydrogels through reactive dip-coating for the formation of immunoactive barriers. Biomaterials. 2011 Sep; 32(26):6204-12. PMID: 21658759.
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    176. Sims EA, Deforest CA, Anseth KS. A Mild, Large-Scale Synthesis of 1,3-Cyclooctanedione: Expanding Access to Difluorinated Cyclooctyne for Copper-Free Click Chemistry. Tetrahedron Lett. 2011 Apr 20; 52(16):1871-1873. PMID: 21709827.
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    177. Lin CC, Anseth KS. Cell-cell communication mimicry with poly(ethylene glycol) hydrogels for enhancing beta-cell function. Proc Natl Acad Sci U S A. 2011 Apr 19; 108(16):6380-5. PMID: 21464290.
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    178. Fairbanks BD, Singh SP, Bowman CN, Anseth KS. Photodegradable, Photoadaptable Hydrogels via Radical-Mediated Disulfide Fragmentation Reaction. Macromolecules. 2011 Apr 26; 44(8):2444-2450. PMID: 21512614.
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    179. Berron BJ, Johnson LM, Ba X, McCall JD, Alvey NJ, Anseth KS, Bowman CN. Glucose oxidase-mediated polymerization as a platform for dual-mode signal amplification and biodetection. Biotechnol Bioeng. 2011 Jul; 108(7):1521-8. PMID: 21337335.
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    180. McCall JD, Lin CC, Anseth KS. Affinity peptides protect transforming growth factor beta during encapsulation in poly(ethylene glycol) hydrogels. Biomacromolecules. 2011 Apr 11; 12(4):1051-7. PMID: 21375234.
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    181. Anderson SB, Lin CC, Kuntzler DV, Anseth KS. The performance of human mesenchymal stem cells encapsulated in cell-degradable polymer-peptide hydrogels. Biomaterials. 2011 May; 32(14):3564-74. PMID: 21334063.
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    182. Adzima BJ, Tao Y, Kloxin CJ, DeForest CA, Anseth KS, Bowman CN. Spatial and temporal control of the alkyne-azide cycloaddition by photoinitiated Cu(II) reduction. Nat Chem. 2011 Mar; 3(3):256-59. PMID: 21336334.
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    183. Papadopoulos A, Bichara DA, Zhao X, Ibusuki S, Randolph MA, Anseth KS, Yaremchuk MJ. Injectable and photopolymerizable tissue-engineered auricular cartilage using poly(ethylene glycol) dimethacrylate copolymer hydrogels. Tissue Eng Part A. 2011 Jan; 17(1-2):161-9. PMID: 20695772.
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    184. Blanchette JO, Langer SJ, Sahai S, Topiwala PS, Leinwand LL, Anseth KS. Use of integrin-linked kinase to extend function of encapsulated pancreatic tissue. Biomed Mater. 2010 Dec; 5(6):061001. PMID: 21060146.
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    187. Sivamani RK, Schwartz MP, Anseth KS, Isseroff RR. Keratinocyte proximity and contact can play a significant role in determining mesenchymal stem cell fate in human tissue. FASEB J. 2011 Jan; 25(1):122-31. PMID: 20847231.
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    189. Lawson MC, Hoth KC, Deforest CA, Bowman CN, Anseth KS. Inhibition of Staphylococcus epidermidis biofilms using polymerizable vancomycin derivatives. Clin Orthop Relat Res. 2010 Aug; 468(8):2081-91. PMID: 20191335.
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    190. Deforest CA, Sims EA, Anseth KS. Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture. Chem Mater. 2010 Aug 24; 22(16):4783-4790. PMID: 20842213.
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    191. Johnson LM, Deforest CA, Pendurti A, Anseth KS, Bowman CN. Formation of three-dimensional hydrogel multilayers using enzyme-mediated redox chain initiation. ACS Appl Mater Interfaces. 2010 Jul; 2(7):1963-72. PMID: 20586415.
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    192. Pedr?n S, Peinado C, Bosch P, Anseth KS. Synthesis and characterization of degradable bioconjugated hydrogels with hyperbranched multifunctional cross-linkers. Acta Biomater. 2010 Nov; 6(11):4189-98. PMID: 20561601.
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    193. Aimetti AA, Feaver KR, Anseth KS. Synthesis of cyclic, multivalent Arg-Gly-Asp using sequential thiol-ene/thiol-yne photoreactions. Chem Commun (Camb). 2010 Aug 21; 46(31):5781-3. PMID: 20552127.
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    194. Pedron S, Kasko AM, Peinado C, Anseth KS. Effect of heparin oligomer chain length on the activation of valvular interstitial cells. Biomacromolecules. 2010 Jun 14; 11(6):1692-5. PMID: 20446725.
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    195. Terella A, Mariner P, Brown N, Anseth K, Streubel SO. Repair of a calvarial defect with biofactor and stem cell-embedded polyethylene glycol scaffold. Arch Facial Plast Surg. 2010 May-Jun; 12(3):166-71. PMID: 20479432.
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    196. Aimetti AA, Shoemaker RK, Lin CC, Anseth KS. On-resin peptide macrocyclization using thiol-ene click chemistry. Chem Commun (Camb). 2010 Jun 21; 46(23):4061-3. PMID: 20379591.
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    197. Hume PS, Anseth KS. Inducing local T cell apoptosis with anti-Fas-functionalized polymeric coatings fabricated via surface-initiated photopolymerizations. Biomaterials. 2010 Apr; 31(12):3166-74. PMID: 20138358.
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    198. Kloxin AM, Tibbitt MW, Kasko AM, Fairbairn JA, Anseth KS. Tunable hydrogels for external manipulation of cellular microenvironments through controlled photodegradation. Adv Mater. 2010 Jan 05; 22(1):61-6. PMID: 20217698.
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    199. Tibbitt MW, Kloxin AM, Dyamenahalli KU, Anseth KS. Controlled two-photon photodegradation of PEG hydrogels to study and manipulate subcellular interactions on soft materials. Soft Matter. 2010; 6(20):5100-5108. PMID: 21984881.
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    200. Lin CC, Boyer PD, Aimetti AA, Anseth KS. Regulating MCP-1 diffusion in affinity hydrogels for enhancing immuno-isolation. J Control Release. 2010 Mar 19; 142(3):384-91. PMID: 19951731.
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    201. Schwartz MP, Fairbanks BD, Rogers RE, Rangarajan R, Zaman MH, Anseth KS. A synthetic strategy for mimicking the extracellular matrix provides new insight about tumor cell migration. Integr Biol (Camb). 2010 Jan; 2(1):32-40. PMID: 20473410.
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    202. Johnson LM, Fairbanks BD, Anseth KS, Bowman CN. Enzyme-mediated redox initiation for hydrogel generation and cellular encapsulation. Biomacromolecules. 2009 Nov 09; 10(11):3114-21. PMID: 19821604.
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    203. Benton JA, DeForest CA, Vivekanandan V, Anseth KS. Photocrosslinking of gelatin macromers to synthesize porous hydrogels that promote valvular interstitial cell function. Tissue Eng Part A. 2009 Nov; 15(11):3221-30. PMID: 19374488.
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    204. Fairbanks BD, Schwartz MP, Halevi AE, Nuttelman CR, Bowman CN, Anseth KS. A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization. Adv Mater. 2009 Dec 28; 21(48):5005-5010. PMID: 25377720.
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    205. Kloxin AM, Benton JA, Anseth KS. In situ elasticity modulation with dynamic substrates to direct cell phenotype. Biomaterials. 2010 Jan; 31(1):1-8. PMID: 19788947.
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    206. Fairbanks BD, Schwartz MP, Bowman CN, Anseth KS. Photoinitiated polymerization of PEG-diacrylate with lithium phenyl-2,4,6-trimethylbenzoylphosphinate: polymerization rate and cytocompatibility. Biomaterials. 2009 Dec; 30(35):6702-7. PMID: 19783300.
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    207. Lin CC, Anseth KS. Glucagon-like peptide-1 functionalized PEG hydrogels promote survival and function of encapsulated pancreatic beta-cells. Biomacromolecules. 2009 Sep 14; 10(9):2460-7. PMID: 19586041.
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    208. Benton JA, Fairbanks BD, Anseth KS. Characterization of valvular interstitial cell function in three dimensional matrix metalloproteinase degradable PEG hydrogels. Biomaterials. 2009 Dec; 30(34):6593-603. PMID: 19747725.
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    209. Weber LM, Lopez CG, Anseth KS. Effects of PEG hydrogel crosslinking density on protein diffusion and encapsulated islet survival and function. J Biomed Mater Res A. 2009 Sep 01; 90(3):720-9. PMID: 18570315.
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    210. Benton JA, Kern HB, Leinwand LA, Mariner PD, Anseth KS. Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression. Arterioscler Thromb Vasc Biol. 2009 Nov; 29(11):1950-7. PMID: 19679827.
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    211. Aimetti AA, Machen AJ, Anseth KS. Poly(ethylene glycol) hydrogels formed by thiol-ene photopolymerization for enzyme-responsive protein delivery. Biomaterials. 2009 Oct; 30(30):6048-54. PMID: 19674784.
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    212. Lawson MC, Shoemaker R, Hoth KB, Bowman CN, Anseth KS. Polymerizable vancomycin derivatives for bactericidal biomaterial surface modification: structure-function evaluation. Biomacromolecules. 2009 Aug 10; 10(8):2221-34. PMID: 19606854.
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    213. Salinas CN, Anseth KS. Decorin moieties tethered into PEG networks induce chondrogenesis of human mesenchymal stem cells. J Biomed Mater Res A. 2009 Aug; 90(2):456-64. PMID: 18546186.
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    214. Salinas CN, Anseth KS. Mesenchymal stem cells for craniofacial tissue regeneration: designing hydrogel delivery vehicles. J Dent Res. 2009 Aug; 88(8):681-92. PMID: 19734453.
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    215. Lin CC, Anseth KS. Controlling Affinity Binding with Peptide-Functionalized Poly(ethylene glycol) Hydrogels. Adv Funct Mater. 2009 Jul 24; 19(14):2325. PMID: 20148198.
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    216. Tibbitt MW, Anseth KS. Hydrogels as extracellular matrix mimics for 3D cell culture. Biotechnol Bioeng. 2009 Jul 01; 103(4):655-63. PMID: 19472329.
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    217. Lin CC, Metters AT, Anseth KS. Functional PEG-peptide hydrogels to modulate local inflammation induced by the pro-inflammatory cytokine TNFalpha. Biomaterials. 2009 Oct; 30(28):4907-14. PMID: 19560813.
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    218. DeForest CA, Polizzotti BD, Anseth KS. Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments. Nat Mater. 2009 Aug; 8(8):659-64. PMID: 19543279.
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    219. Aimetti AA, Tibbitt MW, Anseth KS. Human neutrophil elastase responsive delivery from poly(ethylene glycol) hydrogels. Biomacromolecules. 2009 Jun 08; 10(6):1484-9. PMID: 19408953.
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    220. Kloxin AM, Kasko AM, Salinas CN, Anseth KS. Photodegradable hydrogels for dynamic tuning of physical and chemical properties. Science. 2009 Apr 03; 324(5923):59-63. PMID: 19342581.
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    221. Hwang DK, Oakey J, Toner M, Arthur JA, Anseth KS, Lee S, Zeiger A, Van Vliet KJ, Doyle PS. Stop-flow lithography for the production of shape-evolving degradable microgel particles. J Am Chem Soc. 2009 Apr 01; 131(12):4499-504. PMID: 19215127.
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    222. Lin CC, Anseth KS. PEG hydrogels for the controlled release of biomolecules in regenerative medicine. Pharm Res. 2009 Mar; 26(3):631-43. PMID: 19089601.
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    223. Fairbanks BD, Scott TF, Kloxin CJ, Anseth KS, Bowman CN. Thiol-Yne Photopolymerizations: Novel Mechanism, Kinetics, and Step-Growth Formation of Highly Cross-Linked Networks. Macromolecules. 2009 Jan 13; 42(1):211-217. PMID: 19461871.
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    224. Weber LM, Hayda KN, Anseth KS. Cell-matrix interactions improve beta-cell survival and insulin secretion in three-dimensional culture. Tissue Eng Part A. 2008 Dec; 14(12):1959-68. PMID: 18724831.
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    225. Benton JA, Kern HB, Anseth KS. Substrate properties influence calcification in valvular interstitial cell culture. J Heart Valve Dis. 2008 Nov; 17(6):689-99. PMID: 19137803.
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    226. Khire VS, Kloxin AM, Couch CL, Anseth KS, Bowman CN. Synthesis, Characterization and Cleavage of Linear Polymers Attached to Silica Nanoparticles Formed Using Thiol-acrylate Conjugate Addition Reactions. J Polym Sci A Polym Chem. 2008 Oct 15; 46(20):6896-6906. PMID: 20098666.
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    227. Rice MA, Homier PM, Waters KR, Anseth KS. Effects of directed gel degradation and collagenase digestion on the integration of neocartilage produced by chondrocytes encapsulated in hydrogel carriers. J Tissue Eng Regen Med. 2008 Oct; 2(7):418-29. PMID: 18727135.
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    228. Rice MA, Waters KR, Anseth KS. Ultrasound monitoring of cartilaginous matrix evolution in degradable PEG hydrogels. Acta Biomater. 2009 Jan; 5(1):152-61. PMID: 18793879.
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    229. Benoit DS, Schwartz MP, Durney AR, Anseth KS. Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells. Nat Mater. 2008 Oct; 7(10):816-23. PMID: 18724374.
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    230. Weber LM, Anseth KS. Hydrogel encapsulation environments functionalized with extracellular matrix interactions increase islet insulin secretion. Matrix Biol. 2008 Oct; 27(8):667-73. PMID: 18773957.
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    231. Kloxin AM, Anseth KS. Materials science: Protein gels on the move. Nature. 2008 Aug 07; 454(7205):705-6. PMID: 18685693.
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    232. Rydholm AE, Held NL, Benoit DS, Bowman CN, Anseth KS. Modifying network chemistry in thiol-acrylate photopolymers through postpolymerization functionalization to control cell-material interactions. J Biomed Mater Res A. 2008 Jul; 86(1):23-30. PMID: 17941011.
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    233. Salinas CN, Anseth KS. The influence of the RGD peptide motif and its contextual presentation in PEG gels on human mesenchymal stem cell viability. J Tissue Eng Regen Med. 2008 Jul; 2(5):296-304. PMID: 18512265.
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    234. Polizzotti BD, Fairbanks BD, Anseth KS. Three-dimensional biochemical patterning of click-based composite hydrogels via thiolene photopolymerization. Biomacromolecules. 2008 Apr; 9(4):1084-7. PMID: 18351741.
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    235. Salinas CN, Anseth KS. The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities. Biomaterials. 2008 May; 29(15):2370-7. PMID: 18295878.
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    236. Simms HM, Bowman CM, Anseth KS. Using living radical polymerization to enable facile incorporation of materials in microfluidic cell culture devices. Biomaterials. 2008 May; 29(14):2228-36. PMID: 18294686.
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    237. Nuttelman CR, Rice MA, Rydholm AE, Salinas CN, Shah DN, Anseth KS. Macromolecular Monomers for the Synthesis of Hydrogel Niches and Their Application in Cell Encapsulation and Tissue Engineering. Prog Polym Sci. 2008 Feb; 33(2):167-179. PMID: 19461945.
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    238. Shah DN, Recktenwall-Work SM, Anseth KS. The effect of bioactive hydrogels on the secretion of extracellular matrix molecules by valvular interstitial cells. Biomaterials. 2008 May; 29(13):2060-72. PMID: 18237775.
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    239. Cushing MC, Mariner PD, Liao JT, Sims EA, Anseth KS. Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells. FASEB J. 2008 Jun; 22(6):1769-77. PMID: 18218921.
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    240. Weber LM, Cheung CY, Anseth KS. Multifunctional pancreatic islet encapsulation barriers achieved via multilayer PEG hydrogels. Cell Transplant. 2008; 16(10):1049-57. PMID: 18351021.
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    241. Weber LM, Cheung CY, Anseth KS. Multifunctional Pancreatic Islet Encapsulation Barriers Achieved via Multilayer PEG Hydrogels. Cell Transplant. 2007 Nov; 16(10):1049-1057. PMID: 28866920.
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    242. Lawson MC, Bowman CN, Anseth KS. Vancomycin derivative photopolymerized to titanium kills S. epidermidis. Clin Orthop Relat Res. 2007 Aug; 461:96-105. PMID: 17549033.
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    243. Rydholm AE, Reddy SK, Anseth KS, Bowman CN. Development and Characterization of Degradable Thiol-Allyl Ether Photopolymers. Polymer (Guildf). 2007 Jul 13; 48(15):4589-4600. PMID: 18626514.
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    244. Macdonald KK, Cheung CY, Anseth KS. Cellular delivery of TGFbeta1 promotes osteoinductive signalling for bone regeneration. J Tissue Eng Regen Med. 2007 Jul-Aug; 1(4):314-7. PMID: 18038422.
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    245. Cushing MC, Anseth KS. Materials science. Hydrogel cell cultures. Science. 2007 May 25; 316(5828):1133-4. PMID: 17525324.
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    246. Mahoney MJ, Anseth KS. Contrasting effects of collagen and bFGF-2 on neural cell function in degradable synthetic PEG hydrogels. J Biomed Mater Res A. 2007 May; 81(2):269-78. PMID: 17120204.
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    247. Salinas CN, Cole BB, Kasko AM, Anseth KS. Chondrogenic differentiation potential of human mesenchymal stem cells photoencapsulated within poly(ethylene glycol)-arginine-glycine-aspartic acid-serine thiol-methacrylate mixed-mode networks. Tissue Eng. 2007 May; 13(5):1025-34. PMID: 17417949.
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    248. Benoit DS, Tripodi MC, Blanchette JO, Langer SJ, Leinwand LA, Anseth KS. Integrin-linked kinase production prevents anoikis in human mesenchymal stem cells. J Biomed Mater Res A. 2007 May; 81(2):259-68. PMID: 17335036.
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    249. Cushing MC, Liao JT, Jaeggli MP, Anseth KS. Material-based regulation of the myofibroblast phenotype. Biomaterials. 2007 Aug; 28(23):3378-87. PMID: 17475322.
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    250. Rice MA, Anseth KS. Controlling cartilaginous matrix evolution in hydrogels with degradation triggered by exogenous addition of an enzyme. Tissue Eng. 2007 Apr; 13(4):683-91. PMID: 17266401.
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    251. Weber LM, Hayda KN, Haskins K, Anseth KS. The effects of cell-matrix interactions on encapsulated beta-cell function within hydrogels functionalized with matrix-derived adhesive peptides. Biomaterials. 2007 Jul; 28(19):3004-11. PMID: 17391752.
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    252. Rydholm AE, Anseth KS, Bowman CN. Effects of neighboring sulfides and pH on ester hydrolysis in thiol-acrylate photopolymers. Acta Biomater. 2007 Jul; 3(4):449-55. PMID: 17276150.
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    253. Riddle KW, Kong HJ, Leach JK, Fischbach C, Cheung C, Anseth KS, Mooney DJ. Modifying the proliferative state of target cells to control DNA expression and identifying cell types transfected in vivo. Mol Ther. 2007 Feb; 15(2):361-8. PMID: 17235315.
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    254. Watkins AW, Southard SL, Anseth KS. Characterizing multilaminated hydrogels with spatially varying network structure and solute loading using confocal laser scanning microscopy. Acta Biomater. 2007 Jul; 3(4):439-48. PMID: 17236830.
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    255. Sebra RP, Reddy SK, Masters KS, Bowman CN, Anseth KS. Controlled polymerization chemistry to graft architectures that influence cell-material interactions. Acta Biomater. 2007 Mar; 3(2):151-61. PMID: 17236829.
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    256. Christenson EM, Anseth KS, van den Beucken JJ, Chan CK, Ercan B, Jansen JA, Laurencin CT, Li WJ, Murugan R, Nair LS, Ramakrishna S, Tuan RS, Webster TJ, Mikos AG. Nanobiomaterial applications in orthopedics. J Orthop Res. 2007 Jan; 25(1):11-22. PMID: 17048259.
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    257. Benoit DS, Collins SD, Anseth KS. Multifunctional hydrogels that promote osteogenic hMSC differentiation through stimulation and sequestering of BMP2. Adv Funct Mater. 2007; 17(13):2085-2093. PMID: 18688288.
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    258. Rydholm AE, Held NL, Bowman CN, Anseth KS. Gel Permeation Chromatography Characterization of the Chain Length Distributions in Thiol-Acrylate Photopolymer Networks. Macromolecules. 2006 Nov 14; 39(23):7882-7888. PMID: 19079733.
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    259. Cooper JA, Li WJ, Bailey LO, Hudson SD, Lin-Gibson S, Anseth KS, Tuan RS, Washburn NR. Encapsulated chondrocyte response in a pulsatile flow bioreactor. Acta Biomater. 2007 Jan; 3(1):13-21. PMID: 17097360.
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    260. Rydholm AE, Reddy SK, Anseth KS, Bowman CN. Controlling network structure in degradable thiol-acrylate biomaterials to tune mass loss behavior. Biomacromolecules. 2006 Oct; 7(10):2827-36. PMID: 17025359.
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    261. Benoit DS, Durney AR, Anseth KS. The effect of heparin-functionalized PEG hydrogels on three-dimensional human mesenchymal stem cell osteogenic differentiation. Biomaterials. 2007 Jan; 28(1):66-77. PMID: 16963119.
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    262. Benoit DS, Nuttelman CR, Collins SD, Anseth KS. Synthesis and characterization of a fluvastatin-releasing hydrogel delivery system to modulate hMSC differentiation and function for bone regeneration. Biomaterials. 2006 Dec; 27(36):6102-10. PMID: 16860387.
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    263. Cheung CY, Anseth KS. Synthesis of immunoisolation barriers that provide localized immunosuppression for encapsulated pancreatic islets. Bioconjug Chem. 2006 Jul-Aug; 17(4):1036-42. PMID: 16848413.
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    264. Rice MA, Sanchez-Adams J, Anseth KS. Exogenously triggered, enzymatic degradation of photopolymerized hydrogels with polycaprolactone subunits: experimental observation and modeling of mass loss behavior. Biomacromolecules. 2006 Jun; 7(6):1968-75. PMID: 16768421.
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    265. Benoit DS, Durney AR, Anseth KS. Manipulations in hydrogel degradation behavior enhance osteoblast function and mineralized tissue formation. Tissue Eng. 2006 Jun; 12(6):1663-73. PMID: 16846361.
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    266. Sebra RP, Masters KS, Cheung CY, Bowman CN, Anseth KS. Detection of antigens in biologically complex fluids with photografted whole antibodies. Anal Chem. 2006 May 01; 78(9):3144-51. PMID: 16643006.
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    267. Nuttelman CR, Kloxin AM, Anseth KS. Temporal changes in peg hydrogel structure influence human mesenchymal stem cell proliferation and matrix mineralization. Adv Exp Med Biol. 2006; 585:135-49. PMID: 17120782.
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    268. Nuttelman CR, Tripodi MC, Anseth KS. Dexamethasone-functionalized gels induce osteogenic differentiation of encapsulated hMSCs. J Biomed Mater Res A. 2006 Jan; 76(1):183-95. PMID: 16265650.
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    269. Weber LM, He J, Bradley B, Haskins K, Anseth KS. PEG-based hydrogels as an in vitro encapsulation platform for testing controlled beta-cell microenvironments. Acta Biomater. 2006 Jan; 2(1):1-8. PMID: 16701853.
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    270. Jarmer DJ, Lengsfeld CS, Anseth KS, Randolph TW. Supercritical fluid crystallization of griseofulvin: crystal habit modification with a selective growth inhibitor. J Pharm Sci. 2005 Dec; 94(12):2688-702. PMID: 16258994.
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    271. Mahoney MJ, Anseth KS. Three-dimensional growth and function of neural tissue in degradable polyethylene glycol hydrogels. Biomaterials. 2006 Apr; 27(10):2265-74. PMID: 16318872.
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    272. Sebra RP, Masters KS, Bowman CN, Anseth KS. Surface grafted antibodies: controlled architecture permits enhanced antigen detection. Langmuir. 2005 Nov 22; 21(24):10907-11. PMID: 16285751.
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    273. Cushing MC, Jaeggli MP, Masters KS, Leinwand LA, Anseth KS. Serum deprivation improves seeding and repopulation of acellular matrices with valvular interstitial cells. J Biomed Mater Res A. 2005 Oct 01; 75(1):232-41. PMID: 16088888.
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    274. Nuttelman CR, Benoit DS, Tripodi MC, Anseth KS. The effect of ethylene glycol methacrylate phosphate in PEG hydrogels on mineralization and viability of encapsulated hMSCs. Biomaterials. 2006 Mar; 27(8):1377-86. PMID: 16139351.
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    275. Cushing MC, Liao JT, Anseth KS. Activation of valvular interstitial cells is mediated by transforming growth factor-beta1 interactions with matrix molecules. Matrix Biol. 2005 Sep; 24(6):428-37. PMID: 16055320.
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    276. Benoit DS, Anseth KS. The effect on osteoblast function of colocalized RGD and PHSRN epitopes on PEG surfaces. Biomaterials. 2005 Sep; 26(25):5209-20. PMID: 15792548.
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    277. Gall K, Yakacki CM, Liu Y, Shandas R, Willett N, Anseth KS. Thermomechanics of the shape memory effect in polymers for biomedical applications. J Biomed Mater Res A. 2005 Jun 01; 73(3):339-48. PMID: 15806564.
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    278. Masters KS, Shah DN, Leinwand LA, Anseth KS. Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells. Biomaterials. 2005 May; 26(15):2517-25. PMID: 15585254.
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    279. Nuttelman CR, Tripodi MC, Anseth KS. Synthetic hydrogel niches that promote hMSC viability. Matrix Biol. 2005 May; 24(3):208-18. PMID: 15896949.
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    280. Benoit DS, Anseth KS. Heparin functionalized PEG gels that modulate protein adsorption for hMSC adhesion and differentiation. Acta Biomater. 2005 Jul; 1(4):461-70. PMID: 16701827.
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    281. Rice MA, Dodson BT, Arthur JA, Anseth KS. Cell-based therapies and tissue engineering. Otolaryngol Clin North Am. 2005 Apr; 38(2):199-214, v. PMID: 15823589.
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    282. Rydholm AE, Bowman CN, Anseth KS. Degradable thiol-acrylate photopolymers: polymerization and degradation behavior of an in situ forming biomaterial. Biomaterials. 2005 Aug; 26(22):4495-506. PMID: 15722118.
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    283. Bryant SJ, Arthur JA, Anseth KS. Incorporation of tissue-specific molecules alters chondrocyte metabolism and gene expression in photocrosslinked hydrogels. Acta Biomater. 2005 Mar; 1(2):243-52. PMID: 16701801.
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    284. Simms HM, Brotherton CM, Good BT, Davis RH, Anseth KS, Bowman CN. In situ fabrication of macroporous polymer networks within microfluidic devices by living radical photopolymerization and leaching. Lab Chip. 2005 Feb; 5(2):151-7. PMID: 15672128.
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    285. Masters KS, Shah DN, Walker G, Leinwand LA, Anseth KS. Designing scaffolds for valvular interstitial cells: cell adhesion and function on naturally derived materials. J Biomed Mater Res A. 2004 Oct 01; 71(1):172-80. PMID: 15368267.
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    286. Hutchison JB, Haraldsson KT, Good BT, Sebra RP, Luo N, Anseth KS, Bowman CN. Robust polymer microfluidic device fabrication via contact liquid photolithographic polymerization (CLiPP). Lab Chip. 2004 Dec; 4(6):658-62. PMID: 15570381.
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    287. Rice MA, Anseth KS. Encapsulating chondrocytes in copolymer gels: bimodal degradation kinetics influence cell phenotype and extracellular matrix development. J Biomed Mater Res A. 2004 Sep 15; 70(4):560-8. PMID: 15307160.
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    288. Bryant SJ, Anseth KS, Lee DA, Bader DL. Crosslinking density influences the morphology of chondrocytes photoencapsulated in PEG hydrogels during the application of compressive strain. J Orthop Res. 2004 Sep; 22(5):1143-9. PMID: 15304291.
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    289. Bryant SJ, Bender RJ, Durand KL, Anseth KS. Encapsulating chondrocytes in degrading PEG hydrogels with high modulus: engineering gel structural changes to facilitate cartilaginous tissue production. Biotechnol Bioeng. 2004 Jun 30; 86(7):747-55. PMID: 15162450.
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    290. Walker GA, Masters KS, Shah DN, Anseth KS, Leinwand LA. Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res. 2004 Aug 06; 95(3):253-60. PMID: 15217906.
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    291. Quick DJ, Macdonald KK, Anseth KS. Delivering DNA from photocrosslinked, surface eroding polyanhydrides. J Control Release. 2004 Jun 18; 97(2):333-43. PMID: 15196760.
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    292. Quick DJ, Anseth KS. DNA delivery from photocrosslinked PEG hydrogels: encapsulation efficiency, release profiles, and DNA quality. J Control Release. 2004 Apr 28; 96(2):341-51. PMID: 15081223.
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    293. Nuttelman CR, Tripodi MC, Anseth KS. In vitro osteogenic differentiation of human mesenchymal stem cells photoencapsulated in PEG hydrogels. J Biomed Mater Res A. 2004 Mar 15; 68(4):773-82. PMID: 14986332.
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    294. Bryant SJ, Chowdhury TT, Lee DA, Bader DL, Anseth KS. Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels. Ann Biomed Eng. 2004 Mar; 32(3):407-17. PMID: 15095815.
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    296. Quick DJ, Anseth KS. Gene delivery in tissue engineering: a photopolymer platform to coencapsulate cells and plasmid DNA. Pharm Res. 2003 Nov; 20(11):1730-7. PMID: 14661915.
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    297. Randolph MA, Anseth K, Yaremchuk MJ. Tissue engineering of cartilage. Clin Plast Surg. 2003 Oct; 30(4):519-37. PMID: 14621300.
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    298. Davis KA, Burdick JA, Anseth KS. Photoinitiated crosslinked degradable copolymer networks for tissue engineering applications. Biomaterials. 2003 Jun; 24(14):2485-95. PMID: 12695075.
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    299. Burdick JA, Frankel D, Dernell WS, Anseth KS. An initial investigation of photocurable three-dimensional lactic acid based scaffolds in a critical-sized cranial defect. Biomaterials. 2003 Apr; 24(9):1613-20. PMID: 12559821.
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    300. Martens PJ, Bryant SJ, Anseth KS. Tailoring the degradation of hydrogels formed from multivinyl poly(ethylene glycol) and poly(vinyl alcohol) macromers for cartilage tissue engineering. Biomacromolecules. 2003 Mar-Apr; 4(2):283-92. PMID: 12625723.
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    301. Poshusta AK, Burdick JA, Mortisen DJ, Padera RF, Ruehlman D, Yaszemski MJ, Anseth KS. Histocompatibility of photocrosslinked polyanhydrides: a novel in situ forming orthopaedic biomaterial. J Biomed Mater Res A. 2003 Jan 01; 64(1):62-9. PMID: 12483697.
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    302. Watkins AW, Anseth KS. Copolymerization of photocrosslinkable anhydride monomers for use as a biodegradable bone cement. J Biomater Sci Polym Ed. 2003; 14(3):267-78. PMID: 12713099.
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    303. Burdick JA, Lovestead TM, Anseth KS. Kinetic chain lengths in highly cross-linked networks formed by the photoinitiated polymerization of divinyl monomers: a gel permeation chromatography investigation. Biomacromolecules. 2003 Jan-Feb; 4(1):149-56. PMID: 12523860.
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    304. Bryant SJ, Anseth KS. Controlling the spatial distribution of ECM components in degradable PEG hydrogels for tissue engineering cartilage. J Biomed Mater Res A. 2003 Jan 01; 64(1):70-9. PMID: 12483698.
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    305. Burdick JA, Anseth KS. Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering. Biomaterials. 2002 Nov; 23(22):4315-23. PMID: 12219821.
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    306. Burdick JA, Mason MN, Hinman AD, Thorne K, Anseth KS. Delivery of osteoinductive growth factors from degradable PEG hydrogels influences osteoblast differentiation and mineralization. J Control Release. 2002 Sep 18; 83(1):53-63. PMID: 12220838.
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    307. Nuttelman CR, Henry SM, Anseth KS. Synthesis and characterization of photocrosslinkable, degradable poly(vinyl alcohol)-based tissue engineering scaffolds. Biomaterials. 2002 Sep; 23(17):3617-26. PMID: 12109687.
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    308. Anseth KS, Metters AT, Bryant SJ, Martens PJ, Elisseeff JH, Bowman CN. In situ forming degradable networks and their application in tissue engineering and drug delivery. J Control Release. 2002 Jan 17; 78(1-3):199-209. PMID: 11772461.
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    309. Burdick JA, Padera RF, Huang JV, Anseth KS. An investigation of the cytotoxicity and histocompatibility of in situ forming lactic acid based orthopedic biomaterials. J Biomed Mater Res. 2002; 63(5):484-91. PMID: 12209891.
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    310. Davis KA, Anseth KS. Controlled release from crosslinked degradable networks. Crit Rev Ther Drug Carrier Syst. 2002; 19(4-5):385-423. PMID: 12661698.
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    311. Bryant SJ, Anseth KS. Hydrogel properties influence ECM production by chondrocytes photoencapsulated in poly(ethylene glycol) hydrogels. J Biomed Mater Res. 2002 Jan; 59(1):63-72. PMID: 11745538.
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    312. Poshusta AK, Anseth KS. Photopolymerized biomaterials for application in the temporomandibular joint. Cells Tissues Organs. 2001; 169(3):272-8. PMID: 11455123.
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    313. Burdick JA, Mason MN, Anseth KS. In situ forming lactic acid based orthopaedic biomaterials: influence of oligomer chemistry on osteoblast attachment and function. J Biomater Sci Polym Ed. 2001; 12(11):1253-65. PMID: 11853390.
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    314. Burkoth AK, Anseth KS. A review of photocrosslinked polyanhydrides: in situ forming degradable networks. Biomaterials. 2000 Dec; 21(23):2395-404. PMID: 11055287.
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    315. Burkoth AK, Burdick J, Anseth KS. Surface and bulk modifications to photocrosslinked polyanhydrides to control degradation behavior. J Biomed Mater Res. 2000 Sep 05; 51(3):352-9. PMID: 10880076.
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    316. Elisseeff J, McIntosh W, Anseth K, Riley S, Ragan P, Langer R. Photoencapsulation of chondrocytes in poly(ethylene oxide)-based semi-interpenetrating networks. J Biomed Mater Res. 2000 Aug; 51(2):164-71. PMID: 10825215.
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    317. Young JS, Gonzales KD, Anseth KS. Photopolymers in orthopedics: characterization of novel crosslinked polyanhydrides. Biomaterials. 2000 Jun; 21(11):1181-8. PMID: 10817271.
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    318. Lu S, Ramirez WF, Anseth KS. Photopolymerized, multilaminated matrix devices with optimized nonuniform initial concentration profiles to control drug release. J Pharm Sci. 2000 Jan; 89(1):45-51. PMID: 10664537.
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    319. Bryant SJ, Nuttelman CR, Anseth KS. Cytocompatibility of UV and visible light photoinitiating systems on cultured NIH/3T3 fibroblasts in vitro. J Biomater Sci Polym Ed. 2000; 11(5):439-57. PMID: 10896041.
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    320. Elisseeff J, Anseth K, Sims D, McIntosh W, Randolph M, Yaremchuk M, Langer R. Transdermal photopolymerization of poly(ethylene oxide)-based injectable hydrogels for tissue-engineered cartilage. Plast Reconstr Surg. 1999 Sep; 104(4):1014-22. PMID: 10654741.
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    321. Muggli DS, Burkoth AK, Anseth KS. Crosslinked polyanhydrides for use in orthopedic applications: degradation behavior and mechanics. J Biomed Mater Res. 1999 Aug; 46(2):271-8. PMID: 10380006.
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    322. Elisseeff J, Anseth K, Sims D, McIntosh W, Randolph M, Langer R. Transdermal photopolymerization for minimally invasive implantation. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):3104-7. PMID: 10077644.
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    323. Lu S, Anseth KS. Photopolymerization of multilaminated poly(HEMA) hydrogels for controlled release. J Control Release. 1999 Feb 22; 57(3):291-300. PMID: 9895416.
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    324. Anseth KS, Shastri VR, Langer R. Photopolymerizable degradable polyanhydrides with osteocompatibility. Nat Biotechnol. 1999 Feb; 17(2):156-9. PMID: 10052351.
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    325. Metters AT, Anseth KS, Bowman CN. Fundamental studies of biodegradable hydrogels as cartilage replacement materials. Biomed Sci Instrum. 1999; 35:33-8. PMID: 11143373.
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    326. Bryant SJ, Nuttelman CR, Anseth KS. The effects of crosslinking density on cartilage formation in photocrosslinkable hydrogels. Biomed Sci Instrum. 1999; 35:309-14. PMID: 11143369.
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    327. Anseth KS, Bowman CN, Brannon-Peppas L. Mechanical properties of hydrogels and their experimental determination. Biomaterials. 1996 Sep; 17(17):1647-57. PMID: 8866026.
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    328. Anseth KS, Goodner MD, Reil MA, Kannurpatti AR, Newman SM, Bowman CN. The influence of comonomer composition on dimethacrylate resin properties for dental composites. J Dent Res. 1996 Aug; 75(8):1607-12. PMID: 8906130.
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    329. Mongia NK, Anseth KS, Peppas NA. Mucoadhesive poly(vinyl alcohol) hydrogels produced by freezing/thawing processes: applications in the development of wound healing systems. J Biomater Sci Polym Ed. 1996; 7(12):1055-64. PMID: 8880437.
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