 Cocaine
"Cocaine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
| Descriptor ID |
D003042
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| MeSH Number(s) |
D02.145.074.722.388 D03.132.889.354 D03.605.084.500.722.388 D03.605.869.388
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cocaine".
Below are MeSH descriptors whose meaning is more specific than "Cocaine".
This graph shows the total number of publications written about "Cocaine" by people in this website by year, and whether "Cocaine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 2 | 0 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 4 | 1 | 5 | | 2006 | 2 | 1 | 3 | | 2007 | 11 | 2 | 13 | | 2008 | 9 | 1 | 10 | | 2009 | 7 | 1 | 8 | | 2010 | 8 | 0 | 8 | | 2011 | 12 | 0 | 12 | | 2012 | 7 | 1 | 8 | | 2013 | 11 | 1 | 12 | | 2014 | 5 | 0 | 5 | | 2015 | 2 | 1 | 3 | | 2016 | 3 | 1 | 4 | | 2017 | 1 | 1 | 2 | | 2018 | 2 | 0 | 2 | | 2019 | 2 | 1 | 3 | | 2021 | 3 | 1 | 4 | | 2022 | 3 | 0 | 3 | | 2023 | 4 | 0 | 4 | | 2024 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Cocaine" by people in Profiles.
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Kim TW, Bertholet N, Magane KM, Lloyd-Travaglini C, Winter MR, Samet JH, Erlandson KM, Stein MD, Bryant KJ, Saitz R, Heeren TC. Alcohol Consumption and Illicit Drug Use: Associations With Fall, Fracture, and Acute Health Care Utilization Among People With HIV Infection. J Acquir Immune Defic Syndr. 2024 04 01; 95(4):391-398.
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Neeley KM, Lac A. Experimental Effects of Substance Use Legality (Sober, Alcohol, Marijuana, Cocaine) and Sexual Crime (Indecent Exposure, Rape) on Attributions of Perpetrator Responsibility, Blame, and Punishment. Subst Use Misuse. 2024; 59(4):536-548.
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Pytell JD, Fojo AT, Keruly JC, Snow LN, Falade-Nwulia O, Moore RD, Chander G, Lesko CR. Measuring time in buprenorphine treatment stages among people with HIV and opioid use disorder by retention definition and its association with cocaine and hazardous alcohol use. Addict Sci Clin Pract. 2023 09 02; 18(1):51.
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Lesko CR, Falade-Nwulia OO, Pytell JD, Hutton HE, Fojo AT, Keruly JC, Moore RD, Chander G. Joint effects of substance use disorders and recent substance use on HIV viral non-suppression among people engaged in HIV care in an urban clinic, 2014-2019. Addiction. 2023 11; 118(11):2193-2202.
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Brown KT, Levis SC, O'Neill CE, Levy C, Rice KC, Watkins LR, Bachtell RK. Toll-like receptor 4 antagonists reduce cocaine-primed reinstatement of drug seeking. Psychopharmacology (Berl). 2023 Jul; 240(7):1587-1600.
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Thakrar AP, Pytell JD, Stoller KB, Walters V, Weiss RD, Chander G. Transitioning off methadone: A qualitative study exploring why patients discontinue methadone treatment for opioid use disorder. J Subst Use Addict Treat. 2023 07; 150:209055.
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Macchi ZA, Carlisle TC, Filley CM. Prognosis in substance abuse-related acute toxic leukoencephalopathy: A scoping review. J Neurol Sci. 2022 11 15; 442:120420.
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Calello DP, Aldy K, Jefri M, Nguyen TT, Krotulski A, Logan B, Brent J, Wax P, Walton S, Manini AF. Identification of a novel opioid, N-piperidinyl etonitazene (etonitazepipne), in patients with suspected opioid overdose. Clin Toxicol (Phila). 2022 09; 60(9):1067-1069.
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Rather HA, Mishra S, Su Y, Kumar A, Singh S, Misra BB, Lee J, Furdui CM, Hamilton LR, Gould RW, Nader SH, Nader MA, Deep G. Mass Spectrometry-Based Proteome Profiling of Extracellular Vesicles Derived from the Cerebrospinal Fluid of Adult Rhesus Monkeys Exposed to Cocaine throughout Gestation. Biomolecules. 2022 03 28; 12(4).
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Terasaki D. Cardiovascular medications on discharge for patients with chest pain and concurrent cocaine use. Am J Emerg Med. 2022 08; 58:315-316.
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