 DNA-Binding Proteins
"DNA-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
| Descriptor ID |
D004268
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| MeSH Number(s) |
D12.776.260
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| Concept/Terms |
Single-Stranded DNA Binding Proteins- Single-Stranded DNA Binding Proteins
- Single Stranded DNA Binding Proteins
- SS DNA BP
- DNA Single-Stranded Binding Protein
- DNA Single Stranded Binding Protein
- Single-Stranded DNA-Binding Protein
- DNA-Binding Protein, Single-Stranded
- Single Stranded DNA Binding Protein
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Below are MeSH descriptors whose meaning is more general than "DNA-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "DNA-Binding Proteins".
This graph shows the total number of publications written about "DNA-Binding Proteins" by people in this website by year, and whether "DNA-Binding Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 14 | 7 | 21 | | 1996 | 22 | 9 | 31 | | 1997 | 29 | 12 | 41 | | 1998 | 16 | 11 | 27 | | 1999 | 23 | 14 | 37 | | 2000 | 22 | 19 | 41 | | 2001 | 25 | 27 | 52 | | 2002 | 34 | 28 | 62 | | 2003 | 42 | 28 | 70 | | 2004 | 44 | 37 | 81 | | 2005 | 27 | 32 | 59 | | 2006 | 17 | 15 | 32 | | 2007 | 17 | 5 | 22 | | 2008 | 17 | 6 | 23 | | 2009 | 18 | 11 | 29 | | 2010 | 13 | 10 | 23 | | 2011 | 21 | 20 | 41 | | 2012 | 19 | 21 | 40 | | 2013 | 23 | 20 | 43 | | 2014 | 20 | 16 | 36 | | 2015 | 9 | 12 | 21 | | 2016 | 17 | 18 | 35 | | 2017 | 15 | 17 | 32 | | 2018 | 8 | 9 | 17 | | 2019 | 24 | 13 | 37 | | 2020 | 13 | 14 | 27 | | 2021 | 12 | 8 | 20 | | 2022 | 4 | 10 | 14 | | 2023 | 4 | 9 | 13 | | 2024 | 8 | 12 | 20 | | 2025 | 6 | 2 | 8 |
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Below are the most recent publications written about "DNA-Binding Proteins" by people in Profiles.
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Clune S, Awolade P, Esquer H, Zhou Q, LaBarbera DV. CHD1L in cancer and beyond: structure, oncogenic functions, and therapeutic potential. J Exp Clin Cancer Res. 2025 May 30; 44(1):167.
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Duncalf L, Wang X, Aljabri AA, Campbell AE, Alharbi RQ, Donaldson I, Hayes A, Peti W, Page R, Bennett D. PNUTS:PP1 recruitment to Tox4 regulates chromosomal dispersal in Drosophila germline development. Cell Rep. 2025 May 27; 44(5):115693.
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Vann KR, Sharma R, Hsu CC, Devoucoux M, Tencer AH, Zeng L, Lin K, Zhu L, Li Q, Lachance C, Ospina RR, Tong Q, Cheung KL, Yang S, Biswas S, Xuan H, Gatchalian J, Alamillo L, Wang J, Jang SM, Klein BJ, Lu Y, Ernst P, Strahl BD, Rothbart SB, Walsh MJ, Cleary ML, C?t? J, Shi X, Zhou MM, Kutateladze TG. Structure-function relationship of ASH1L and histone H3K36 and H3K4 methylation. Nat Commun. 2025 Mar 06; 16(1):2235.
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Esquer H, Zhou Q, LaBarbera DV. Targeted Inhibition of CHD1L by OTI-611 Reprograms Chemotherapy and Targeted Therapy-Induced Cell Cycle Arrest and Suppresses Proliferation to Produce Synergistic Antitumor Effects in Breast and Colorectal Cancer. Cells. 2025 02 20; 14(5).
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Biswas S, Lee JE, Xie G, Masclef L, Ren Z, C?t? J, Affar EB, Ge K, Kutateladze TG. Colorectal cancer hot spot mutations attenuate the ASXL-MLL4 interaction. J Biol Chem. 2025 Mar; 301(3):108333.
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Heidarian Y, Fasteen TD, Mungcal L, Buddika K, Mahmoudzadeh NH, Nemkov T, D'Alessandro A, Tennessen JM. Hypoxia-inducible factor 1a is required to establish the larval glycolytic program in Drosophila melanogaster. Mol Metab. 2025 Mar; 93:102106.
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Becht DC, Selvam K, Lachance C, C?t? V, Li K, Nguyen MC, Pareek A, Shi X, Wen H, Blanco MA, C?t? J, Kutateladze TG. A multivalent engagement of ENL with MOZ. Nat Struct Mol Biol. 2025 Apr; 32(4):709-718.
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Singh S, Arya G, Mishra R, Singla S, Pratap A, Upadhayay K, Sharma M, Chaba R. Molecular mechanisms underlying allosteric behavior of Escherichia coli DgoR, a GntR/FadR family transcriptional regulator. Nucleic Acids Res. 2025 Jan 07; 53(1).
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Campodonico W, Mohan HM, Huynh PT, Black HH, Lau CI, Paulson HL, Sharkey LM, Whiteley AM. The gag-like gene RTL8 antagonizes PEG10-mediated virus like particles. PLoS One. 2024; 19(12):e0310946.
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Sala R, Esquer H, Kellett T, Clune S, Awolade P, Pike LA, Zhou Q, Messersmith WA, LaBarbera DV. CHD1L Inhibitor OTI-611 Synergizes with Chemotherapy to Enhance Antitumor Efficacy and Prolong Survival in Colorectal Cancer Mouse Models. Int J Mol Sci. 2024 Dec 07; 25(23).
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