 DNA-Binding Proteins
"DNA-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
| Descriptor ID |
D004268
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| MeSH Number(s) |
D12.776.260
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| Concept/Terms |
Single-Stranded DNA Binding Proteins- Single-Stranded DNA Binding Proteins
- Single Stranded DNA Binding Proteins
- SS DNA BP
- DNA Single-Stranded Binding Protein
- DNA Single Stranded Binding Protein
- Single-Stranded DNA-Binding Protein
- DNA-Binding Protein, Single-Stranded
- Single Stranded DNA Binding Protein
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Below are MeSH descriptors whose meaning is more general than "DNA-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "DNA-Binding Proteins".
This graph shows the total number of publications written about "DNA-Binding Proteins" by people in this website by year, and whether "DNA-Binding Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 23 | 8 | 31 | | 1997 | 31 | 12 | 43 | | 1998 | 20 | 13 | 33 | | 1999 | 26 | 14 | 40 | | 2000 | 23 | 21 | 44 | | 2001 | 23 | 29 | 52 | | 2002 | 36 | 29 | 65 | | 2003 | 41 | 27 | 68 | | 2004 | 44 | 38 | 82 | | 2005 | 28 | 33 | 61 | | 2006 | 19 | 17 | 36 | | 2007 | 17 | 5 | 22 | | 2008 | 17 | 5 | 22 | | 2009 | 17 | 16 | 33 | | 2010 | 16 | 11 | 27 | | 2011 | 21 | 20 | 41 | | 2012 | 20 | 23 | 43 | | 2013 | 25 | 18 | 43 | | 2014 | 21 | 16 | 37 | | 2015 | 10 | 17 | 27 | | 2016 | 21 | 19 | 40 | | 2017 | 17 | 16 | 33 | | 2018 | 11 | 12 | 23 | | 2019 | 24 | 15 | 39 | | 2020 | 18 | 14 | 32 | | 2021 | 16 | 11 | 27 | | 2022 | 6 | 10 | 16 | | 2023 | 4 | 13 | 17 | | 2024 | 8 | 12 | 20 | | 2025 | 13 | 8 | 21 | | 2026 | 4 | 2 | 6 |
To return to the timeline, click here.
Below are the most recent publications written about "DNA-Binding Proteins" by people in Profiles.
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Kendirli PK, Erdem S, Kisaarslan AP, Gök V, Kayhan E, Özcan A, Dogan ME, Klein C, Ünal E, Eken A. A novel ELF4 gene variant disrupts T and NK cell function in a patient with immune thrombocytopenia (ITP). Inflamm Res. 2026 May 19; 75(1).
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Kardian AS, Sun H, Ippagunta S, Laboe N, Varadharajan S, Yu K, Chen HC, Emanus E, Zheng T, Deneen RM, Connelly JP, Wang YD, Zhan J, Liu H, Lowe K, Bugbee T, Pathak R, Bland A, Mehta S, Cochiolo S, Arabzade A, Holcomb B, Budd KM, Kembuan G, Wright T, Caesar E, Park M, Hancock A, Gee D, Murdoch J, Xiao Y, McBrayer SK, Merchant TE, Qi J, Durbin AD, Schwarz LA, Wang L, Donson AM, Foreman NK, Agnihotri S, Lavado A, Baker SJ, Ellison DW, Lee HK, Pruett-Miller SM, Bertrand KC, Deneen B, Mack SC. Dominant clones leverage developmental epigenomic states to drive ependymoma. Nature. 2026 04; 652(8111):1027-1037.
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Xu H, Kapur P, Christie A, Nielsen AW, Perny A, Brandenburg O, Small C, Miyata J, Zhong H, Roberts C, Elias R, Tcheuyap V, Duarte C, van Bokhoven A, Panian J, Li H, Collier KA, Zynger D, Meza L, Beuselinck B, Agarwal N, Mortazavi A, Pal S, McKay R, Lam ET, Rajaram S, Brugarolas J. Determinants of pancreatic tropism in metastatic renal cell carcinoma. JCI Insight. 2026 Mar 09; 11(5).
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Al Dala Ali M, Longepied G, Lévy N, Metzler-Guillemain C, Mitchell MJ. Nucleoporin NUP210L and BAF-paralogue BAF-L redundantly ensure nuclear integrity and manchette microtubule organisation in mouse spermatids. Hum Mol Genet. 2026 Feb 10; 35(3).
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Biswas S, Tavaf Z, Benz C, Khalil M, Becht DC, Simonetti L, Blanco MA, Affar EB, Ivarsson Y, Kutateladze TG. A tryptophan-phenylalanine binding motif for the histone methyltransferases MLL4 and MLL3. J Biol Chem. 2026 Mar; 302(3):111189.
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Bai X, Zhang J, Wang S, Huang K, Pan Z, Liang A, Wu W, Yu Z, Chen Y, Tong Y, Dai S, Chen Z. Novel intermolecular zinc fingers and redox-driven conformational changes dictate tumor suppressor ZMYND11's role in cooperative recognition of diverse targets. Nucleic Acids Res. 2026 Jan 22; 54(3).
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Moffatt C, Arora A, Vaeth KF, Guzman BB, Bhardwaj G, Hoelscher A, Gifford LB, Russ HA, Dominguez D, Taliaferro JM. TDP-43 directly inhibits mRNA accumulation in neurites through modulation of mRNA stability. EMBO J. 2026 Feb; 45(3):692-721.
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Saiduzzaman SM, Xu R, Sampad MJN, Hoffman RN, Seiler ST, Brail Q, Yurevych V, Walker ZJ, Wells TN, Ong EM, Yuzvinsky TD, Hawkins AR, Salama SR, Teodorescu M, Haussler D, Schmidt H. Single molecule nanopore counting assay targeting small extracellular vesicle cargo for non-invasive monitoring of cerebral organoid development and health. Sci Rep. 2025 Dec 12; 15(1):45806.
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Yu Z, Vromman A, Nguyen NQH, Schuermans A, Li L, Rentz T, Nakao T, Vellarikkal SK, Uddin MM, Niroula A, Griffin G, Honigberg MC, Lin AE, Gibson CJ, Katz DH, Tahir UA, Fang S, Dron JS, Pan M, Haidermota S, Ganesh S, Antoine T, Weinstock J, Austin TR, Vasan RS, Peloso GM, Hornsby W, Ganz P, Manson JE, Haring B, Kooperberg C, Reiner AP, Bis JC, Psaty BM, Min YI, Correa A, Lange LA, Post WS, Rotter JI, Rich SS, Wilson JG, Ebert BL, Yu B, Ballantyne CM, Coresh J, Sankaran VG, Bick AG, Jaiswal S, Gerszten RE, Libby P, Gupta RM, Natarajan P. Human plasma proteomic profile of clonal hematopoiesis. Nat Commun. 2025 Nov 27; 16(1):11688.
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Mirzaa GM, Yan K, Relator R, Levesque M, Jayasinghe P, Timpano S, Yalcin B, Collins S, Ziegler A, Pao E, Oyama N, Brischoux-Boucher E, Piard J, Monaghan KG, Guillen Sacoto MJ, Dobyns WB, Park KL, Fernández-Mayoralas DM, Fernández-Jaén A, Jayakar P, Palomares-Bralo M, Santos-Simarro F, Brusco A, Antona V, Giorgio E, Kvarnung M, Isidor B, Conrad S, Cogné B, Deb W, Stuurman KE, ?terbová K, Smal N, Weckhuysen S, Oegema R, Innes AM, Koboldt DC, Ben-Omran T, Yeh RC, Kruer MC, Bakhtiari S, Papavasiliou A, Moutton S, Nambot S, Chanprasert S, Paolucci SA, Miller K, Burton B, Kim K, O'Heir E, Bruwer Z, Donald KA, Kleefstra T, Goldstein A, Angle B, Bontempo K, Miny P, Joset P, Demurger F, Hobson E, Pang L, Carpenter L, Li D, Bonneau D, Sadikovic B, Picketts DJ. Pathogenic variants in SMARCA1 cause an X-linked neurodevelopmental disorder modulated by NURF complex composition. Nat Commun. 2025 Nov 10; 16(1):9875.
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