 p38 Mitogen-Activated Protein Kinases
"p38 Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.
| Descriptor ID |
D048051
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.843 D12.644.360.450.835 D12.776.476.450.835
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| Concept/Terms |
p38 Mitogen-Activated Protein Kinases- p38 Mitogen-Activated Protein Kinases
- p38 Mitogen Activated Protein Kinases
- p38 MAP Kinase
- MAP Kinase, p38
- p38 MAPK
- MAPK, p38
- p38 SAPK
- Mitogen-Activated Protein Kinase p38
- Mitogen Activated Protein Kinase p38
- p38 Protein Kinase
- Protein Kinase, p38
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Below are MeSH descriptors whose meaning is more general than "p38 Mitogen-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "p38 Mitogen-Activated Protein Kinases".
This graph shows the total number of publications written about "p38 Mitogen-Activated Protein Kinases" by people in this website by year, and whether "p38 Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 0 | 1 | 1 | | 1997 | 0 | 3 | 3 | | 1998 | 0 | 8 | 8 | | 1999 | 0 | 8 | 8 | | 2000 | 0 | 6 | 6 | | 2001 | 0 | 8 | 8 | | 2002 | 0 | 14 | 14 | | 2003 | 0 | 14 | 14 | | 2004 | 3 | 16 | 19 | | 2005 | 2 | 7 | 9 | | 2006 | 4 | 4 | 8 | | 2007 | 3 | 2 | 5 | | 2008 | 2 | 5 | 7 | | 2009 | 4 | 5 | 9 | | 2010 | 3 | 5 | 8 | | 2011 | 3 | 2 | 5 | | 2012 | 1 | 6 | 7 | | 2013 | 1 | 5 | 6 | | 2014 | 2 | 8 | 10 | | 2015 | 1 | 8 | 9 | | 2016 | 2 | 6 | 8 | | 2017 | 0 | 2 | 2 | | 2018 | 0 | 3 | 3 | | 2019 | 0 | 4 | 4 | | 2020 | 1 | 1 | 2 | | 2021 | 1 | 1 | 2 | | 2022 | 1 | 1 | 2 | | 2024 | 0 | 1 | 1 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "p38 Mitogen-Activated Protein Kinases" by people in Profiles.
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Hoffman TE, Tian C, Nangia V, Yang C, Regot S, Gerosa L, Spencer SL. CDK2 activity crosstalk on the ERK kinase translocation reporter can be resolved computationally. Cell Syst. 2025 Jan 15; 16(1):101162.
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Vinnakota JM, Biavasco F, Schwabenland M, Chhatbar C, Adams RC, Erny D, Duquesne S, El Khawanky N, Schmidt D, Fetsch V, Z?hringer A, Sali? H, Athanassopoulos D, Braun LM, Javorniczky NR, Ho JNHG, Kierdorf K, Marks R, W?sch R, Simonetta F, Andrieux G, Pfeifer D, Monaco G, Capitini C, Fry TJ, Blank T, Blazar BR, Wagner E, Theobald M, Sommer C, Stelljes M, Reicherts C, Jeibmann A, Schittenhelm J, Monoranu CM, Rosenwald A, Kort?m M, Rasche L, Einsele H, Meyer PT, Brumberg J, V?lkl S, Mackensen A, Coras R, von Bergwelt-Baildon M, Albert NL, Bartos LM, Brendel M, Holzgreve A, Mack M, Boerries M, Mackall CL, Duyster J, Henneke P, Priller J, K?hler N, Str?bing F, Bengsch B, Ruella M, Subklewe M, von Baumgarten L, Gill S, Prinz M, Zeiser R. Targeting TGF?-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome. Nat Cancer. 2024 Aug; 5(8):1227-1249.
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Hazegh K, Fang F, Kelly K, Sinchar D, Wang L, Zuchelkowski BE, Ufelle AC, Esparza O, Davizon-Castillo P, Page GP, Kanias T. Erythrocyte mitogen-activated protein kinases mediate hemolytic events under osmotic and oxidative stress and in hemolytic diseases. Cell Signal. 2022 11; 99:110450.
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Raghavan S, Kundumani-Sridharan V, Kumar S, White CW, Das KC. Thioredoxin Prevents Loss of UCP2 in Hyperoxia via MKK4-p38 MAPK-PGC1a Signaling and Limits Oxygen Toxicity. Am J Respir Cell Mol Biol. 2022 03; 66(3):323-336.
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Bansal A, Mostafa MM, Kooi C, Sasse SK, Michi AN, Shah SV, Leigh R, Gerber AN, Newton R. Interplay between nuclear factor-?B, p38 MAPK, and glucocorticoid receptor signaling synergistically induces functional TLR2 in lung epithelial cells. J Biol Chem. 2022 04; 298(4):101747.
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Chalimeswamy A, Thanuja MY, Ranganath SH, Pandya K, Kompella UB, Srinivas SP. Oxidative Stress Induces a Breakdown of the Cytoskeleton and Tight Junctions of the Corneal Endothelial Cells. J Ocul Pharmacol Ther. 2022 Jan-Feb; 38(1):74-84.
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Keleher MR, Erickson K, Smith HA, Kechris KJ, Yang IV, Dabelea D, Friedman JE, Boyle KE, Jansson T. Placental Insulin/IGF-1 Signaling, PGC-1a, and Inflammatory Pathways Are Associated With Metabolic Outcomes at 4-6 Years of Age: The ECHO Healthy Start Cohort. Diabetes. 2021 03; 70(3):745-751.
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Younis US, Chu HW, Kraft M, Ledford JG. A 20-Mer Peptide Derived from the Lectin Domain of SP-A2 Decreases Tumor Necrosis Factor Alpha Production during Mycoplasma pneumoniae Infection. Infect Immun. 2020 08 19; 88(9).
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Weaver BP, Weaver YM, Omi S, Yuan W, Ewbank JJ, Han M. Non-Canonical Caspase Activity Antagonizes p38 MAPK Stress-Priming Function to Support Development. Dev Cell. 2020 05 04; 53(3):358-369.e6.
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Walrath T, Malizia RA, Zhu X, Sharp SP, D'Souza SS, Lopez-Soler R, Parr B, Kartchner B, Lee EC, Stain SC, Iwakura Y, O'Connor W. IFN-? and IL-17A regulate intestinal crypt production of CXCL10 in the healthy and inflamed colon. Am J Physiol Gastrointest Liver Physiol. 2020 03 01; 318(3):G479-G489.
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