Platelet-Derived Growth Factor
"Platelet-Derived Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.
Descriptor ID |
D010982
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MeSH Number(s) |
D12.644.276.910 D12.776.124.625 D12.776.467.910 D23.529.910
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Concept/Terms |
Platelet-Derived Growth Factor- Platelet-Derived Growth Factor
- Factor, Platelet-Derived Growth
- Growth Factor, Platelet-Derived
- Platelet Derived Growth Factor
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Below are MeSH descriptors whose meaning is more general than "Platelet-Derived Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Platelet-Derived Growth Factor".
This graph shows the total number of publications written about "Platelet-Derived Growth Factor" by people in this website by year, and whether "Platelet-Derived Growth Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 3 | 4 | 1996 | 1 | 1 | 2 | 1997 | 1 | 2 | 3 | 1998 | 2 | 0 | 2 | 1999 | 0 | 1 | 1 | 2001 | 1 | 1 | 2 | 2002 | 1 | 0 | 1 | 2003 | 5 | 2 | 7 | 2004 | 0 | 1 | 1 | 2005 | 2 | 0 | 2 | 2006 | 1 | 3 | 4 | 2008 | 0 | 1 | 1 | 2009 | 0 | 2 | 2 | 2010 | 1 | 0 | 1 | 2011 | 0 | 1 | 1 | 2012 | 1 | 3 | 4 | 2014 | 1 | 0 | 1 | 2016 | 0 | 1 | 1 | 2017 | 1 | 0 | 1 | 2018 | 0 | 1 | 1 | 2019 | 1 | 0 | 1 | 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Platelet-Derived Growth Factor" by people in Profiles.
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Zanotto GM, Liesbeny P, Barrett M, Zlotnick H, Frank E, Grodzinsky AJ, Frisbie DD. Microfracture Augmentation With Trypsin Pretreatment and Growth Factor-Functionalized Self-assembling Peptide Hydrogel Scaffold in an Equine Model. Am J Sports Med. 2021 07; 49(9):2498-2508.
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Zhu N, Swietlik EM, Welch CL, Pauciulo MW, Hagen JJ, Zhou X, Guo Y, Karten J, Pandya D, Tilly T, Lutz KA, Martin JM, Treacy CM, Rosenzweig EB, Krishnan U, Coleman AW, Gonzaga-Jauregui C, Lawrie A, Trembath RC, Wilkins MR, Morrell NW, Shen Y, Gr?f S, Nichols WC, Chung WK. Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH. Genome Med. 2021 05 10; 13(1):80.
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Strand KA, Lu S, Mutryn MF, Li L, Zhou Q, Enyart BT, Jolly AJ, Dubner AM, Moulton KS, Nemenoff RA, Koch KA, LaBarbera DV, Weiser-Evans MCM. High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling. Arterioscler Thromb Vasc Biol. 2020 08; 40(8):1854-1869.
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Rocker AJ, Lee DJ, Shandas R, Park D. Injectable Polymeric Delivery System for Spatiotemporal and Sequential Release of Therapeutic Proteins To Promote Therapeutic Angiogenesis and Reduce Inflammation. ACS Biomater Sci Eng. 2020 02 10; 6(2):1217-1227.
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Zanotto G, Liebesny P, Barrett M, Zlotnick H, Grodzinsky A, Frisbie D. Trypsin Pre-Treatment Combined With Growth Factor Functionalized Self-Assembling Peptide Hydrogel Improves Cartilage Repair in Rabbit Model. J Orthop Res. 2019 11; 37(11):2307-2315.
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Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, Rhee JW, Churko JM, Chaudhary R, Chour T, Wang PJ, Snyder MP, Chang HY, Karakikes I, Wu JC. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature. 2019 08; 572(7769):335-340.
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McGraw MD, Dysart MM, Hendry-Hofer TB, Houin PR, Rioux JS, Garlick RB, Loader JE, Smith R, Paradiso DC, Holmes WW, Anderson DR, White CW, Veress LA. Bronchiolitis Obliterans and Pulmonary Fibrosis after Sulfur Mustard Inhalation in Rats. Am J Respir Cell Mol Biol. 2018 06; 58(6):696-705.
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Qu F, Holloway JL, Esterhai JL, Burdick JA, Mauck RL. Programmed biomolecule delivery to enable and direct cell migration for connective tissue repair. Nat Commun. 2017 11 24; 8(1):1780.
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Oak P, Pritzke T, Thiel I, Koschlig M, Mous DS, Windhorst A, Jain N, Eickelberg O, Foerster K, Schulze A, Goepel W, Reicherzer T, Ehrhardt H, Rottier RJ, Ahnert P, Gortner L, Desai TJ, Hilgendorff A. Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung?disease. EMBO Mol Med. 2017 11; 9(11):1504-1520.
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Kusko RL, Brothers JF, Tedrow J, Pandit K, Huleihel L, Perdomo C, Liu G, Juan-Guardela B, Kass D, Zhang S, Lenburg M, Martinez F, Quackenbush J, Sciurba F, Limper A, Geraci M, Yang I, Schwartz DA, Beane J, Spira A, Kaminski N. Integrated Genomics Reveals Convergent Transcriptomic Networks Underlying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2016 10 15; 194(8):948-960.
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