SOX9 Transcription Factor
"SOX9 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A SOXE transcription factor that plays a critical role in regulating CHONDROGENESIS; OSTEOGENESIS; and male sex determination. Loss of function of the SOX9 transcription factor due to genetic mutations is a cause of CAMPOMELIC DYSPLASIA.
| Descriptor ID |
D055758
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| MeSH Number(s) |
D12.776.260.719.500.500 D12.776.660.235.400.750.500.500 D12.776.664.235.400.750.500.500 D12.776.930.823.500.500
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| Concept/Terms |
SOX9 Transcription Factor- SOX9 Transcription Factor
- Transcription Factor, SOX9
- SOX-9 Transcription Factor
- SOX 9 Transcription Factor
- Transcription Factor, SOX-9
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Below are MeSH descriptors whose meaning is more general than "SOX9 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "SOX9 Transcription Factor".
This graph shows the total number of publications written about "SOX9 Transcription Factor" by people in this website by year, and whether "SOX9 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 2 | 2 | | 2007 | 0 | 2 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 0 | 1 | 1 | | 2025 | 1 | 0 | 1 | | 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "SOX9 Transcription Factor" by people in Profiles.
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Lazarevic S, Perez-Cervantes C, Wang Z, Shen KM, Gadek M, Xiao J, Yamaguchi N, Hall JM, Koca Y, Chapski DJ, Rosa-Garrido M, Rubino M, Nadadur RD, McKinsey TA, Vondriska TM, Ruthenburg AJ, Pott S, Park DS, Moskowitz IP. A reduced TBX5-dependent gene regulatory network links atrial fibrillation and heart failure. Nat Cardiovasc Res. 2026 Feb; 5(2):96-117.
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Choi DJ, Murali S, Kwon W, Woo J, Song EC, Ko Y, Sardar D, Lozzi B, Cheng YT, Williamson MR, Huang TW, Sanchez K, Jankowsky J, Deneen B. Astrocytic Sox9 overexpression in Alzheimer's disease mouse models promotes Aß plaque phagocytosis and preserves cognitive function. Nat Neurosci. 2026 Jan; 29(1):88-99.
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Brooks EC, Han SJY, Bonatto Paese CL, Lewis AA, Aarnio-Peterson M, Brugmann SA. The ciliary protein C2cd3 is required for mandibular musculoskeletal tissue patterning. Differentiation. 2024 Jul-Aug; 138:100782.
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Zhong H, Lu W, Tang Y, Wiel C, Wei Y, Cao J, Riedlinger G, Papagiannakopoulos T, Guo JY, Bergo MO, Kang Y, Ganesan S, Sabaawy HE, Pine SR. SOX9 drives KRAS-induced lung adenocarcinoma progression and suppresses anti-tumor immunity. Oncogene. 2023 06; 42(27):2183-2194.
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Sardar D, Chen HC, Reyes A, Varadharajan S, Jain A, Mohila C, Curry R, Lozzi B, Rajendran K, Cervantes A, Yu K, Jalali A, Rao G, Mack SC, Deneen B. Sox9 directs divergent epigenomic states in brain tumor subtypes. Proc Natl Acad Sci U S A. 2022 07 19; 119(29):e2202015119.
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Lin X, Gaudino SJ, Jang KK, Bahadur T, Singh A, Banerjee A, Beaupre M, Chu T, Wong HT, Kim CK, Kempen C, Axelrad J, Huang H, Khalid S, Shah V, Eskiocak O, Parks OB, Berisha A, McAleer JP, Good M, Hoshino M, Blumberg R, Bialkowska AB, Gaffen SL, Kolls JK, Yang VW, Beyaz S, Cadwell K, Kumar P. IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity. 2022 02 08; 55(2):237-253.e8.
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Ung K, Huang TW, Lozzi B, Woo J, Hanson E, Pekarek B, Tepe B, Sardar D, Cheng YT, Liu G, Deneen B, Arenkiel BR. Olfactory bulb astrocytes mediate sensory circuit processing through Sox9 in the mouse brain. Nat Commun. 2021 09 01; 12(1):5230.
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Peron M, Dinarello A, Meneghetti G, Martorano L, Facchinello N, Vettori A, Licciardello G, Tiso N, Argenton F. The stem-like Stat3-responsive cells of zebrafish intestine are Wnt/ß-catenin dependent. Development. 2020 06 19; 147(12).
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Moser HL, Doe AP, Meier K, Garnier S, Laudier D, Akiyama H, Zumstein MA, Galatz LM, Huang AH. Genetic lineage tracing of targeted cell populations during enthesis healing. J Orthop Res. 2018 12; 36(12):3275-3284.
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Wang JS, Infante CR, Park S, Menke DB. PITX1 promotes chondrogenesis and myogenesis in mouse hindlimbs through conserved regulatory targets. Dev Biol. 2018 02 01; 434(1):186-195.
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