 Ryanodine Receptor Calcium Release Channel
"Ryanodine Receptor Calcium Release Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.
| Descriptor ID |
D019837
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| MeSH Number(s) |
D12.776.157.530.400.150.800 D12.776.210.500.800 D12.776.543.550.450.150.800 D12.776.543.585.400.150.800
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| Concept/Terms |
Ryanodine Receptor Calcium Release Channel- Ryanodine Receptor Calcium Release Channel
- Receptor, Ryanodine
- Ca Release Channel-Ryanodine Receptor
- Ca Release Channel Ryanodine Receptor
- Calcium-Ryanodine Receptor Complex
- Calcium Ryanodine Receptor Complex
- Complex, Calcium-Ryanodine Receptor
- Receptor Complex, Calcium-Ryanodine
- Ryanodine Receptor
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Below are MeSH descriptors whose meaning is more general than "Ryanodine Receptor Calcium Release Channel".
Below are MeSH descriptors whose meaning is more specific than "Ryanodine Receptor Calcium Release Channel".
This graph shows the total number of publications written about "Ryanodine Receptor Calcium Release Channel" by people in this website by year, and whether "Ryanodine Receptor Calcium Release Channel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 3 | 3 | | 1997 | 0 | 2 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 2 | 0 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 2 | 3 | | 2005 | 2 | 1 | 3 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 2 | 1 | 3 | | 2010 | 2 | 2 | 4 | | 2012 | 3 | 1 | 4 | | 2014 | 1 | 2 | 3 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 1 | 3 | | 2018 | 1 | 2 | 3 | | 2021 | 3 | 0 | 3 | | 2022 | 2 | 0 | 2 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ryanodine Receptor Calcium Release Channel" by people in Profiles.
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Feng W, Lopez JR, Antrobus S, Zheng J, Uryash A, Dong Y, Beqollari D, Bannister RA, Hopkins PM, Beam KG, Allen PD, Pessah IN. Putative malignant hyperthermia mutation CaV1.1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance. J Biol Chem. 2023 08; 299(8):104992.
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Harvey KE, Tang S, LaVigne EK, Pratt EPS, Hockerman GH. RyR2 regulates store-operated Ca2+ entry, phospholipase C activity, and electrical excitability in the insulinoma cell line INS-1. PLoS One. 2023; 18(5):e0285316.
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Harvey KE, LaVigne EK, Dar MS, Salyer AE, Pratt EPS, Sample PA, Aryal UK, Gowher H, Hockerman GH. RyR2/IRBIT regulates insulin gene transcript, insulin content, and secretion in the insulinoma cell line INS-1. Sci Rep. 2022 05 11; 12(1):7713.
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Dayal A, Perni S, Franzini-Armstrong C, Beam KG, Grabner M. The distal C terminus of the dihydropyridine receptor ?1a subunit is essential for tetrad formation in skeletal muscle. Proc Natl Acad Sci U S A. 2022 05 10; 119(19):e2201136119.
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Perni S, Beam K. Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence. J Gen Physiol. 2022 09 05; 154(9).
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Perni S. The Builders of the Junction: Roles of Junctophilin1 and Junctophilin2 in the Assembly of the Sarcoplasmic Reticulum-Plasma Membrane Junctions in Striated Muscle. Biomolecules. 2022 01 10; 12(1).
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Guo W, Zhu C, Yin Z, Zhang Y, Wang C, Walk AS, Lin YH, McKinsey TA, Woulfe KC, Ren J, Chew HG. The ryanodine receptor stabilizer S107 ameliorates contractility of adult Rbm20 knockout rat cardiomyocytes. Physiol Rep. 2021 09; 9(17):e15011.
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Perni S, Beam K. Neuronal junctophilins recruit specific CaV and RyR isoforms to ER-PM junctions and functionally alter CaV2.1 and CaV2.2. Elife. 2021 03 26; 10.
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Sun B, Yao J, Ni M, Wei J, Zhong X, Guo W, Zhang L, Wang R, Belke D, Chen YX, Lieve KVV, Broendberg AK, Roston TM, Blankoff I, Kammeraad JA, von Alvensleben JC, Lazarte J, Vallmitjana A, Bohne LJ, Rose RA, Benitez R, Hove-Madsen L, Napolitano C, Hegele RA, Fill M, Sanatani S, Wilde AAM, Roberts JD, Priori SG, Jensen HK, Chen SRW. Cardiac ryanodine receptor calcium release deficiency syndrome. Sci Transl Med. 2021 02 03; 13(579).
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Woulfe KC, Wilson CE, Nau S, Chau S, Phillips EK, Zang S, Tompkins C, Sucharov CC, Miyamoto SD, Stauffer BL. Acute isoproterenol leads to age-dependent arrhythmogenesis in guinea pigs. Am J Physiol Heart Circ Physiol. 2018 10 01; 315(4):H1051-H1062.
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