Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Timothy McKinsey

Concepts (682)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Histone Deacetylases
74
2024
211
13.610
Why?
Histone Deacetylase Inhibitors
33
2023
206
7.010
Why?
Cardiomegaly
35
2025
172
6.320
Why?
Myocardium
38
2025
981
5.370
Why?
Myocytes, Cardiac
37
2025
484
5.310
Why?
Heart Failure
32
2025
2142
4.980
Why?
Fibroblasts
26
2024
946
3.280
Why?
Fibrosis
20
2024
518
3.120
Why?
Heart
18
2022
650
3.010
Why?
Ventricular Remodeling
14
2025
255
2.970
Why?
Transcription Factors
33
2024
1634
2.630
Why?
Protein Kinase C
18
2015
258
2.570
Why?
Nuclear Proteins
10
2024
644
2.150
Why?
Myofibrils
8
2023
50
2.050
Why?
Signal Transduction
54
2025
4857
2.030
Why?
Animals
142
2025
34628
1.990
Why?
Adipocytes
5
2025
204
1.850
Why?
Epigenesis, Genetic
12
2023
613
1.850
Why?
Myofibroblasts
5
2023
132
1.790
Why?
Thermogenesis
4
2025
44
1.760
Why?
Rats
49
2022
5236
1.740
Why?
Hypertrophy, Right Ventricular
4
2021
145
1.740
Why?
Chromatin
10
2024
470
1.530
Why?
Extracellular Matrix
6
2023
493
1.530
Why?
Gene Expression Regulation
32
2022
2520
1.470
Why?
Cells, Cultured
36
2024
4048
1.450
Why?
Mice
67
2025
16543
1.430
Why?
Rats, Sprague-Dawley
31
2021
2308
1.390
Why?
Dual-Specificity Phosphatases
3
2021
11
1.320
Why?
Protein Processing, Post-Translational
8
2023
448
1.280
Why?
Hypertension, Pulmonary
11
2021
1876
1.230
Why?
Histones
13
2020
584
1.220
Why?
Azepines
4
2024
87
1.210
Why?
Heart Ventricles
13
2022
778
1.170
Why?
Angiotensin II
5
2021
92
1.140
Why?
Triazoles
4
2024
153
1.120
Why?
Adipose Tissue
4
2025
588
1.110
Why?
Myocardial Reperfusion Injury
2
2024
126
1.060
Why?
Heart-Assist Devices
2
2022
529
1.000
Why?
Gene Expression Regulation, Enzymologic
7
2019
289
0.990
Why?
Phosphorylation
27
2023
1685
0.990
Why?
Cell Cycle Proteins
5
2024
576
0.990
Why?
DNA-Binding Proteins
32
2005
1423
0.970
Why?
Hydroxamic Acids
6
2018
88
0.950
Why?
Lysine
6
2022
266
0.950
Why?
Vascular Remodeling
3
2021
186
0.930
Why?
Muscle, Skeletal
12
2023
1629
0.920
Why?
Acetylation
15
2020
235
0.910
Why?
Myocytes, Smooth Muscle
5
2021
246
0.880
Why?
Humans
103
2025
128896
0.870
Why?
A Kinase Anchor Proteins
1
2024
69
0.850
Why?
Catecholamines
1
2023
96
0.850
Why?
Disease Models, Animal
23
2025
3994
0.840
Why?
Sarcomeres
3
2022
92
0.840
Why?
Histocompatibility Antigens Class II
1
2024
359
0.840
Why?
Repressor Proteins
15
2019
400
0.820
Why?
Heart Diseases
4
2021
356
0.810
Why?
Adipose Tissue, Brown
2
2023
50
0.810
Why?
Myocardial Infarction
4
2024
1031
0.800
Why?
Rejuvenation
1
2022
18
0.800
Why?
Aortic Valve Insufficiency
1
2022
47
0.770
Why?
Mice, Inbred C57BL
22
2025
5270
0.760
Why?
Cell Proliferation
5
2021
2337
0.760
Why?
Assisted Circulation
1
2021
25
0.750
Why?
Macrophages
5
2024
1452
0.750
Why?
Animals, Newborn
14
2017
813
0.730
Why?
Cell Nucleus
13
2015
569
0.730
Why?
MEF2 Transcription Factors
20
2020
62
0.730
Why?
Heart Murmurs
1
2021
13
0.730
Why?
Ventricular Dysfunction, Left
2
2022
387
0.720
Why?
Obesity
4
2025
2844
0.720
Why?
Epigenomics
3
2021
111
0.700
Why?
Arteries
1
2022
268
0.690
Why?
Aortic Diseases
1
2021
112
0.690
Why?
Phosphoric Monoester Hydrolases
1
2020
54
0.690
Why?
Muscle Proteins
6
2025
224
0.670
Why?
Adaptor Proteins, Signal Transducing
2
2017
395
0.670
Why?
Mice, Knockout
12
2024
2770
0.670
Why?
Histone Deacetylase 6
6
2022
19
0.660
Why?
NF-kappa B
11
2024
685
0.650
Why?
Calcium-Calmodulin-Dependent Protein Kinases
12
2006
181
0.640
Why?
NF-E2-Related Factor 2
1
2019
76
0.610
Why?
Calcineurin
12
2008
90
0.600
Why?
Pulmonary Artery
4
2021
1091
0.600
Why?
I-kappa B Proteins
8
2000
77
0.590
Why?
Myogenic Regulatory Factors
18
2009
56
0.590
Why?
T-Lymphocytes
6
2022
1905
0.580
Why?
Drug Discovery
2
2016
130
0.580
Why?
Oxidative Stress
3
2019
1220
0.580
Why?
Immunotherapy
1
2022
579
0.560
Why?
High-Throughput Screening Assays
2
2016
134
0.560
Why?
Models, Biological
15
2022
1702
0.560
Why?
Intracellular Signaling Peptides and Proteins
4
2019
420
0.560
Why?
Carrier Proteins
8
2013
728
0.560
Why?
Karyopherins
2
2009
17
0.550
Why?
Muscle, Smooth, Vascular
5
2021
430
0.540
Why?
Extracellular Signal-Regulated MAP Kinases
2
2017
165
0.540
Why?
Histone Acetyltransferases
3
2014
63
0.540
Why?
Male
53
2025
63146
0.520
Why?
Receptors, Cytoplasmic and Nuclear
4
2009
210
0.520
Why?
Fatty Liver
1
2018
230
0.510
Why?
Protein Binding
13
2019
2086
0.500
Why?
Alkaline Phosphatase
2
2017
148
0.500
Why?
Active Transport, Cell Nucleus
10
2010
112
0.500
Why?
Blood Pressure
6
2022
1743
0.490
Why?
Transforming Growth Factor beta
6
2021
460
0.490
Why?
Enzyme Inhibitors
6
2016
827
0.480
Why?
Microtubules
1
2017
252
0.480
Why?
Transcription, Genetic
17
2014
1408
0.480
Why?
Sumoylation
1
2014
16
0.470
Why?
Carbazoles
1
2015
84
0.470
Why?
Phosphodiesterase 5 Inhibitors
1
2014
37
0.470
Why?
Receptors, Endothelin
1
2014
50
0.470
Why?
SUMO-1 Protein
1
2014
20
0.460
Why?
Cardiotonic Agents
2
2014
128
0.450
Why?
MicroRNAs
4
2021
668
0.450
Why?
Pyrroles
1
2015
201
0.440
Why?
Muscular Atrophy
1
2014
79
0.430
Why?
YY1 Transcription Factor
2
2015
28
0.420
Why?
Phenotype
9
2025
3059
0.410
Why?
Stroke Volume
6
2025
587
0.410
Why?
Calcium
4
2023
1173
0.400
Why?
Myocardial Contraction
5
2023
336
0.400
Why?
Isoenzymes
7
2017
303
0.390
Why?
Enhancer Elements, Genetic
5
2024
177
0.390
Why?
Cardiovascular Agents
3
2025
155
0.380
Why?
Transcriptome
6
2025
871
0.380
Why?
Immunoblotting
5
2014
302
0.370
Why?
Troponin I
2
2023
75
0.370
Why?
Chromatin Assembly and Disassembly
2
2024
101
0.360
Why?
Membrane Glycoproteins
2
2005
465
0.350
Why?
Myosin Heavy Chains
4
2010
173
0.350
Why?
Connectin
2
2022
32
0.350
Why?
Stem Cell Transplantation
2
2021
167
0.350
Why?
Nuclear Localization Signals
1
2010
15
0.340
Why?
Benzamides
3
2019
191
0.340
Why?
RNA Polymerase II
3
2019
313
0.340
Why?
HEK293 Cells
4
2019
673
0.330
Why?
COS Cells
9
2010
185
0.330
Why?
Cell Line
17
2021
2759
0.330
Why?
Induced Pluripotent Stem Cells
3
2021
219
0.320
Why?
RNA-Binding Proteins
3
2021
382
0.320
Why?
Membrane Proteins
1
2015
1100
0.310
Why?
Ventricular Function, Left
3
2025
526
0.310
Why?
Cardiomyopathy, Dilated
4
2025
373
0.310
Why?
Chromatography, High Pressure Liquid
1
2010
484
0.310
Why?
Protein Isoforms
4
2013
369
0.310
Why?
Mitogen-Activated Protein Kinase 3
2
2022
154
0.300
Why?
Inflammation Mediators
3
2021
503
0.290
Why?
Diabetes Mellitus, Type 2
1
2022
2421
0.290
Why?
Cardiomyopathies
2
2023
333
0.290
Why?
Amino Acid Sequence
12
2016
2047
0.280
Why?
Aortic Valve
3
2022
425
0.280
Why?
Protein Kinase Inhibitors
2
2011
870
0.280
Why?
TRPC Cation Channels
1
2006
12
0.270
Why?
Cell Differentiation
8
2021
1854
0.270
Why?
Ankyrins
2
2005
9
0.260
Why?
Female
28
2025
68162
0.260
Why?
Hydrogels
3
2023
634
0.250
Why?
RNA, Messenger
9
2022
2700
0.250
Why?
GATA4 Transcription Factor
4
2020
17
0.250
Why?
Small Molecule Libraries
2
2016
85
0.250
Why?
Stress, Physiological
2
2006
412
0.250
Why?
Acetyltransferases
2
2002
22
0.240
Why?
Protein Kinases
2
2007
305
0.240
Why?
Aging
2
2015
1767
0.240
Why?
Proteins
4
2021
945
0.240
Why?
Citalopram
1
2025
34
0.240
Why?
Primary Ovarian Insufficiency
1
2025
34
0.240
Why?
Acylation
2
2022
28
0.240
Why?
Cortical Bone
2
2021
19
0.240
Why?
Cardiac Output, Low
1
2005
66
0.230
Why?
Calcium Signaling
4
2015
236
0.230
Why?
3T3-L1 Cells
2
2022
34
0.230
Why?
MAP Kinase Signaling System
3
2021
305
0.230
Why?
Cyclophilins
1
2024
34
0.230
Why?
Estrogens
2
2020
348
0.230
Why?
Gene Expression Regulation, Developmental
4
2021
816
0.230
Why?
Cardiomyopathy, Hypertrophic
2
2021
129
0.230
Why?
Sequence Analysis, RNA
3
2021
422
0.220
Why?
Hypertension
3
2011
1236
0.220
Why?
Uncoupling Protein 1
1
2023
15
0.220
Why?
Mice, Transgenic
12
2023
2073
0.220
Why?
Transforming Growth Factor beta1
2
2022
162
0.220
Why?
Autophagy
2
2017
263
0.220
Why?
Adaptation, Physiological
4
2017
516
0.220
Why?
Transcriptional Activation
7
2013
360
0.220
Why?
Hypoxia
5
2013
1070
0.210
Why?
Diet, High-Fat
3
2022
240
0.210
Why?
Calcinosis
2
2017
255
0.210
Why?
Reverse Transcriptase Polymerase Chain Reaction
5
2013
957
0.210
Why?
Arrhythmias, Cardiac
2
2017
312
0.210
Why?
Genetic Therapy
1
2005
292
0.210
Why?
Cell Communication
1
2024
292
0.210
Why?
Valproic Acid
2
2013
47
0.200
Why?
Acute Kidney Injury
2
2022
786
0.200
Why?
Inflammation
4
2017
2694
0.200
Why?
Endocardium
1
2022
32
0.200
Why?
Metalloproteases
1
2022
42
0.200
Why?
Enzyme Activation
6
2022
811
0.200
Why?
Molecular Sequence Data
13
2011
2842
0.200
Why?
Macrophage Activation
2
2021
178
0.190
Why?
NFATC Transcription Factors
6
2006
80
0.190
Why?
Cell Physiological Phenomena
1
2002
21
0.190
Why?
Cellular Senescence
1
2023
176
0.190
Why?
Matrix Metalloproteinases, Secreted
1
2021
11
0.190
Why?
Long Term Adverse Effects
1
2021
10
0.190
Why?
ADAMTS4 Protein
1
2021
15
0.190
Why?
Muscular Dystrophy, Duchenne
1
2023
94
0.190
Why?
Menopause
1
2025
301
0.190
Why?
Hemodynamics
2
2018
1095
0.190
Why?
Immunohistochemistry
4
2021
1694
0.190
Why?
Receptor, Platelet-Derived Growth Factor alpha
1
2022
48
0.190
Why?
Thiazepines
1
2021
6
0.190
Why?
Proteomics
3
2025
985
0.190
Why?
Tyrosine 3-Monooxygenase
2
2001
74
0.190
Why?
Polymerase Chain Reaction
3
2013
1045
0.190
Why?
Homeodomain Proteins
2
2024
480
0.190
Why?
Saccharomyces cerevisiae Proteins
2
2002
367
0.190
Why?
Ryanodine Receptor Calcium Release Channel
1
2021
60
0.180
Why?
Paracrine Communication
1
2021
61
0.180
Why?
Structure-Activity Relationship
6
2011
539
0.180
Why?
Adenylate Kinase
3
2013
26
0.180
Why?
Proteome
1
2025
423
0.180
Why?
Heart Rate
1
2025
807
0.180
Why?
Naphthyridines
2
2010
16
0.180
Why?
Serine
5
2006
133
0.180
Why?
Drug Evaluation, Preclinical
2
2011
173
0.180
Why?
Vasoconstrictor Agents
1
2021
130
0.180
Why?
Leptin
1
2022
217
0.170
Why?
Exosomes
1
2021
95
0.170
Why?
RNA Interference
2
2013
448
0.170
Why?
Microscopy, Fluorescence
3
2009
404
0.170
Why?
Jumonji Domain-Containing Histone Demethylases
1
2020
60
0.170
Why?
Histone Deacetylase 2
3
2013
10
0.170
Why?
Machine Learning
1
2025
417
0.170
Why?
Aminopyridines
2
2010
96
0.170
Why?
Immunoglobulins
1
2000
158
0.170
Why?
Catalytic Domain
3
2015
217
0.170
Why?
Succinic Acid
1
2019
38
0.170
Why?
Protein Transport
3
2009
423
0.160
Why?
Diastole
1
2020
151
0.160
Why?
Histone Deacetylase 1
2
2017
22
0.160
Why?
Serum
1
2019
57
0.160
Why?
Ventricular Function
1
2019
61
0.160
Why?
Biomimetics
1
2019
37
0.160
Why?
Energy Metabolism
3
2022
837
0.160
Why?
Oxadiazoles
1
2019
35
0.160
Why?
Reperfusion Injury
1
2022
274
0.160
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
1
2021
271
0.160
Why?
Phosphodiesterase 3 Inhibitors
1
2019
14
0.160
Why?
Pyrimidines
2
2013
444
0.160
Why?
Cardio-Renal Syndrome
1
2019
13
0.160
Why?
Heart Failure, Diastolic
1
2019
21
0.160
Why?
Receptor Cross-Talk
1
2018
21
0.160
Why?
Wound Healing
1
2021
308
0.160
Why?
Cardiovascular Diseases
4
2025
2013
0.150
Why?
Histone Code
1
2018
31
0.150
Why?
Cell Culture Techniques
1
2021
350
0.150
Why?
p38 Mitogen-Activated Protein Kinases
1
2019
267
0.150
Why?
Mitochondria, Heart
1
2019
93
0.150
Why?
Biopsy
1
2022
1093
0.150
Why?
3' Untranslated Regions
2
2016
137
0.150
Why?
Adipose Tissue, White
1
2018
37
0.150
Why?
Middle Aged
11
2025
30977
0.150
Why?
Cell Adhesion Molecules
1
2019
177
0.150
Why?
Metal Nanoparticles
1
2019
81
0.150
Why?
Gold
1
2019
116
0.150
Why?
RNA, Small Interfering
3
2011
575
0.150
Why?
Myocardial Ischemia
1
2019
254
0.150
Why?
Synovial Membrane
2
2016
84
0.150
Why?
Case-Control Studies
3
2021
3334
0.150
Why?
Amides
2
2009
91
0.140
Why?
Tumor Necrosis Factor-alpha
3
2017
1204
0.140
Why?
Mitogen-Activated Protein Kinase 14
1
2017
6
0.140
Why?
Protein Domains
1
2019
243
0.140
Why?
Mitochondrial Proteins
1
2019
234
0.140
Why?
14-3-3 Proteins
3
2010
17
0.140
Why?
Feedback, Physiological
1
2017
74
0.140
Why?
Adenoviridae
2
2011
193
0.140
Why?
Metabolic Syndrome
1
2021
339
0.140
Why?
Myosins
1
2018
133
0.140
Why?
Calcium-Calmodulin-Dependent Protein Kinase Type 2
4
2008
175
0.140
Why?
NAV1.5 Voltage-Gated Sodium Channel
1
2017
10
0.140
Why?
Calcineurin Inhibitors
3
2004
62
0.140
Why?
JNK Mitogen-Activated Protein Kinases
1
2017
159
0.140
Why?
Human T-lymphotropic virus 1
2
1996
28
0.140
Why?
Stem Cells
1
2021
572
0.140
Why?
Kidney
2
2022
1330
0.140
Why?
Down-Regulation
2
2016
637
0.140
Why?
Tubulin
2
2015
131
0.140
Why?
Transcatheter Aortic Valve Replacement
1
2019
168
0.140
Why?
Gap Junctions
1
2017
62
0.140
Why?
Lymphocyte Activation
2
2000
1091
0.140
Why?
Tissue Scaffolds
1
2019
193
0.140
Why?
Arthritis, Rheumatoid
2
2016
1105
0.130
Why?
CapZ Actin Capping Protein
1
2016
2
0.130
Why?
Tryptophan Hydroxylase
1
2016
55
0.130
Why?
Synoviocytes
1
2016
10
0.130
Why?
Gene Knockdown Techniques
1
2017
315
0.130
Why?
Gene Products, tat
1
1996
22
0.130
Why?
Transcription Elongation, Genetic
1
2016
22
0.130
Why?
Transcription Initiation Site
1
2016
43
0.130
Why?
Cell Movement
4
2015
932
0.130
Why?
Reactive Oxygen Species
1
2019
575
0.130
Why?
RNA, Long Noncoding
1
2018
175
0.130
Why?
Pyridines
2
2012
472
0.130
Why?
Serum Response Factor
1
2016
30
0.130
Why?
Molecular Imaging
1
2016
54
0.130
Why?
Binding Sites
6
2008
1238
0.130
Why?
Cellular Reprogramming Techniques
1
2015
11
0.120
Why?
Ischemia
1
2019
396
0.120
Why?
Cell Cycle
2
2019
581
0.120
Why?
Hypertrophy
3
2023
120
0.120
Why?
Positron-Emission Tomography
1
2017
284
0.120
Why?
Reproducibility of Results
3
2019
3042
0.120
Why?
MyoD Protein
4
2002
32
0.120
Why?
Interleukins
1
2017
245
0.120
Why?
Tissue Engineering
1
2019
389
0.120
Why?
Ventricular Function, Right
1
2017
274
0.120
Why?
rho-Associated Kinases
1
2015
83
0.120
Why?
Osteogenesis
1
2017
190
0.120
Why?
PTEN Phosphohydrolase
1
2016
148
0.120
Why?
Chagas Cardiomyopathy
1
2015
21
0.120
Why?
Cellular Reprogramming
1
2015
95
0.120
Why?
Promoter Regions, Genetic
5
2016
1194
0.110
Why?
Transcription Factor CHOP
1
2014
29
0.110
Why?
Endopeptidases
1
2014
82
0.110
Why?
Biocatalysis
1
2014
66
0.110
Why?
Positive Transcriptional Elongation Factor B
1
2014
29
0.110
Why?
Superoxide Dismutase
1
2016
328
0.110
Why?
Systole
1
2014
190
0.110
Why?
Transfection
8
2015
904
0.110
Why?
Estrogen Receptor beta
1
2013
34
0.110
Why?
Physical Exertion
1
2014
215
0.110
Why?
Gonadotropin-Releasing Hormone
1
2015
207
0.110
Why?
Aortic Valve Stenosis
1
2017
291
0.100
Why?
Phosphoproteins
3
2001
326
0.100
Why?
Interleukin-1beta
3
2024
376
0.100
Why?
Proto-Oncogene Proteins c-akt
1
2015
418
0.100
Why?
Mitogen-Activated Protein Kinase 1
1
2013
184
0.100
Why?
Protein Biosynthesis
1
2014
409
0.100
Why?
Recombinant Proteins
7
2017
1304
0.100
Why?
Membrane Transport Proteins
1
2013
148
0.100
Why?
Endoplasmic Reticulum
1
2014
256
0.100
Why?
Endothelin-1
2
2011
179
0.100
Why?
Retroviridae Proteins, Oncogenic
3
1997
11
0.100
Why?
Tumor Suppressor Proteins
1
2014
313
0.100
Why?
Adrenergic beta-1 Receptor Agonists
1
2011
5
0.090
Why?
Vascular Diseases
1
2014
241
0.090
Why?
Indoles
1
2014
378
0.090
Why?
Azoles
1
2011
4
0.090
Why?
Cell Size
2
2016
86
0.090
Why?
Receptors, Adrenergic, alpha-1
1
2011
44
0.090
Why?
Cats
2
2022
211
0.090
Why?
2,2'-Dipyridyl
1
2010
6
0.090
Why?
Dose-Response Relationship, Drug
3
2022
1968
0.090
Why?
Single-Cell Analysis
2
2024
265
0.090
Why?
Rats, Inbred Dahl
3
2020
7
0.090
Why?
Kinetics
4
2006
1619
0.090
Why?
Saccharomyces cerevisiae
3
2005
517
0.090
Why?
Norepinephrine
1
2011
218
0.090
Why?
Cyclic AMP-Dependent Protein Kinases
1
2011
134
0.090
Why?
Heart Defects, Congenital
1
2017
752
0.090
Why?
Consensus Sequence
1
2010
72
0.090
Why?
Estradiol
1
2013
494
0.080
Why?
Electrophoresis, Polyacrylamide Gel
1
2010
325
0.080
Why?
Molecular Structure
2
2011
469
0.080
Why?
Insulin Resistance
1
2018
1163
0.080
Why?
Flow Cytometry
1
2013
1146
0.080
Why?
Atrial Natriuretic Factor
3
2004
56
0.080
Why?
Regional Blood Flow
1
2012
462
0.080
Why?
Mutation
6
2014
3671
0.080
Why?
Models, Animal
1
2011
370
0.080
Why?
Immunoprecipitation
1
2009
159
0.080
Why?
Protein Interaction Mapping
1
2010
107
0.080
Why?
Embryo, Mammalian
3
2020
223
0.080
Why?
Aged
5
2025
22035
0.080
Why?
Cytokines
2
2014
1995
0.080
Why?
Cell Survival
3
2015
1082
0.080
Why?
Precipitin Tests
3
2004
94
0.080
Why?
Cattle
4
2013
970
0.080
Why?
Phenylephrine
2
2021
75
0.080
Why?
NF-KappaB Inhibitor alpha
5
2000
49
0.080
Why?
Immunologic Factors
1
2011
227
0.080
Why?
Cyclosporine
2
1999
172
0.080
Why?
Aniline Compounds
1
2009
95
0.080
Why?
Muscle Fibers, Skeletal
2
2020
187
0.080
Why?
Adult
8
2019
35361
0.080
Why?
Drug Design
1
2009
156
0.080
Why?
Renal Insufficiency, Chronic
1
2014
561
0.070
Why?
Organ Culture Techniques
2
2019
144
0.070
Why?
Piperazines
1
2010
326
0.070
Why?
Swine
2
2021
740
0.070
Why?
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
1
2007
28
0.070
Why?
Proto-Oncogene Proteins
3
1996
636
0.070
Why?
Muscle Fatigue
1
2008
101
0.070
Why?
Substrate Specificity
2
2006
372
0.070
Why?
Diet
1
2014
1205
0.070
Why?
Aged, 80 and over
1
2018
7050
0.070
Why?
Neurons
1
2015
1425
0.070
Why?
Neovascularization, Physiologic
1
2008
179
0.070
Why?
Rats, Inbred WF
1
2006
5
0.070
Why?
Cocaine-Related Disorders
1
2007
108
0.070
Why?
Thiadiazoles
1
2006
24
0.070
Why?
Rats, Inbred SHR
1
2006
43
0.070
Why?
Cell Transformation, Neoplastic
2
2000
322
0.070
Why?
Apoptosis
4
2021
2481
0.070
Why?
Biological Transport
2
2013
394
0.070
Why?
Drug Delivery Systems
1
2009
328
0.060
Why?
Inositol 1,4,5-Trisphosphate
1
2006
30
0.060
Why?
Anilides
1
2006
72
0.060
Why?
Kidney Diseases
1
2010
366
0.060
Why?
Transcription Factor RelA
2
2024
85
0.060
Why?
Nuclear Envelope
1
2006
28
0.060
Why?
Adenosine Diphosphate
1
2006
78
0.060
Why?
Models, Genetic
3
2004
586
0.060
Why?
Protein Structure, Tertiary
2
2008
832
0.060
Why?
Gene Deletion
3
2017
374
0.060
Why?
Pneumonia
1
2011
612
0.060
Why?
Vinyl Compounds
1
2025
6
0.060
Why?
Cyclohexenes
1
2025
7
0.060
Why?
Base Sequence
6
2006
2157
0.060
Why?
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
1
2025
26
0.060
Why?
Models, Anatomic
1
2006
94
0.060
Why?
Receptors, Cell Surface
1
2007
379
0.060
Why?
Vascular Endothelial Growth Factor A
1
2008
528
0.060
Why?
CX3C Chemokine Receptor 1
1
2024
21
0.060
Why?
Fluoresceins
1
2004
47
0.060
Why?
Research Design
2
2022
1038
0.060
Why?
Adhesins, Bacterial
1
2004
40
0.060
Why?
Potassium Channels
1
2025
139
0.060
Why?
Chromatin Immunoprecipitation
2
2015
132
0.060
Why?
Metabolomics
2
2019
592
0.060
Why?
Administration, Oral
3
2011
783
0.060
Why?
Adenosine Triphosphate
1
2006
474
0.050
Why?
Time Factors
1
2014
6568
0.050
Why?
Real-Time Polymerase Chain Reaction
2
2015
326
0.050
Why?
NG-Nitroarginine Methyl Ester
1
2023
45
0.050
Why?
Green Fluorescent Proteins
1
2004
392
0.050
Why?
Action Potentials
2
2017
463
0.050
Why?
Jurkat Cells
2
2000
136
0.050
Why?
Methylation
2
2019
227
0.050
Why?
Tyrosine
1
2023
219
0.050
Why?
Fluorescent Dyes
1
2004
319
0.050
Why?
Adrenergic beta-Antagonists
1
2025
320
0.050
Why?
Cell Division
2
2002
800
0.050
Why?
Carbamates
1
2023
45
0.050
Why?
Sex Factors
2
2022
1947
0.050
Why?
Protein-Arginine N-Methyltransferases
1
2002
28
0.050
Why?
Protein-Tyrosine Kinases
2
2023
421
0.050
Why?
Enzyme-Linked Immunosorbent Assay
1
2004
822
0.050
Why?
Sex Characteristics
2
2019
722
0.050
Why?
Massachusetts
1
2022
159
0.050
Why?
Mice, Obese
1
2022
55
0.050
Why?
Chromosomal Proteins, Non-Histone
1
2002
111
0.050
Why?
Nuclear Receptor Coactivator 2
1
2001
2
0.050
Why?
RNA, Small Nucleolar
1
2021
8
0.050
Why?
Nuclear Receptor Co-Repressor 2
1
2001
15
0.050
Why?
Rats, Transgenic
1
2021
15
0.050
Why?
Gene Expression
4
2016
1476
0.050
Why?
Rats, Inbred BN
1
2021
52
0.050
Why?
p300-CBP Transcription Factors
1
2001
21
0.050
Why?
Swine, Miniature
1
2021
76
0.050
Why?
Embryonic and Fetal Development
1
2001
95
0.050
Why?
Sequence Deletion
1
2001
180
0.050
Why?
Muscle Development
1
2001
103
0.040
Why?
Blotting, Western
2
2015
1188
0.040
Why?
Cytoplasm
3
2015
260
0.040
Why?
American Heart Association
1
2022
311
0.040
Why?
Culture Media
1
2021
168
0.040
Why?
DNA Primers
3
1996
522
0.040
Why?
Peptides
1
2006
902
0.040
Why?
B-Lymphocytes
1
2006
813
0.040
Why?
Muscle Cells
2
2010
41
0.040
Why?
Receptors, Antigen, T-Cell
1
2004
699
0.040
Why?
Double-Blind Method
1
2025
1858
0.040
Why?
Cell Death
1
2002
342
0.040
Why?
Mutagenesis
1
2000
178
0.040
Why?
Genes, ras
1
2000
97
0.040
Why?
Genetic Engineering
1
2000
89
0.040
Why?
Lung
3
2020
3925
0.040
Why?
Stress, Psychological
1
2007
1051
0.040
Why?
Cyclic Nucleotide Phosphodiesterases, Type 3
1
2019
10
0.040
Why?
Serotonin
2
2016
321
0.040
Why?
Pregnancy
2
2022
6247
0.040
Why?
Pharmacogenomic Testing
1
2019
59
0.040
Why?
Coculture Techniques
1
2019
217
0.040
Why?
Sequence Homology, Amino Acid
3
2008
369
0.040
Why?
Cyclic AMP
1
2019
230
0.040
Why?
Hypertrophy, Left Ventricular
1
1999
127
0.040
Why?
RNA
1
2004
877
0.040
Why?
Glomerular Filtration Rate
1
2022
684
0.040
Why?
Fatty Acids
1
2021
415
0.040
Why?
Antibodies, Monoclonal
1
2004
1359
0.040
Why?
Antigens, CD
1
2000
479
0.040
Why?
Congresses as Topic
1
2019
217
0.040
Why?
Materials Testing
1
2019
344
0.040
Why?
Body Weight
1
2022
931
0.040
Why?
Fluorine Radioisotopes
1
2017
11
0.030
Why?
Autoradiography
1
2017
76
0.030
Why?
Papio
1
2017
97
0.030
Why?
Tissue Donors
1
2019
398
0.030
Why?
Bone Morphogenetic Protein 2
1
2017
76
0.030
Why?
Enzyme Repression
1
2016
6
0.030
Why?
Calcium-Calmodulin-Dependent Protein Kinase Type 4
3
2000
7
0.030
Why?
Antihypertensive Agents
2
2010
487
0.030
Why?
Protein Kinase C-epsilon
1
2016
26
0.030
Why?
Radiopharmaceuticals
1
2017
167
0.030
Why?
STAT1 Transcription Factor
1
2016
69
0.030
Why?
Cysteine Endopeptidases
1
1996
67
0.030
Why?
Multienzyme Complexes
1
1996
69
0.030
Why?
Interferon-beta
1
2016
88
0.030
Why?
Recombinant Fusion Proteins
3
2004
640
0.030
Why?
Polymorphism, Genetic
1
2019
641
0.030
Why?
Echocardiography
1
2019
634
0.030
Why?
Metabolome
1
2019
316
0.030
Why?
DNA Methylation
1
2020
600
0.030
Why?
Collagen Type III
1
2015
15
0.030
Why?
Proteasome Endopeptidase Complex
1
1996
145
0.030
Why?
Models, Molecular
2
2010
1477
0.030
Why?
Lymphocytes
1
1997
369
0.030
Why?
Interferon Regulatory Factor-1
1
2014
13
0.030
Why?
Cardiomegaly, Exercise-Induced
1
2014
3
0.030
Why?
Matrix Metalloproteinase 1
1
2014
18
0.030
Why?
Clathrin
1
1995
26
0.030
Why?
Blood Sedimentation
1
2014
34
0.030
Why?
Muscle Fibers, Slow-Twitch
2
2008
10
0.030
Why?
Soybean Proteins
1
2014
14
0.030
Why?
Viral Proteins
1
1997
329
0.030
Why?
T-Box Domain Proteins
1
2015
95
0.030
Why?
Acetyl-CoA Carboxylase
1
2014
33
0.030
Why?
Gene Regulatory Networks
1
2017
278
0.030
Why?
Caseins
1
2014
18
0.030
Why?
Trypanosoma cruzi
1
2015
24
0.030
Why?
Ketocholesterols
1
2014
7
0.030
Why?
alpha-Crystallin B Chain
1
2014
18
0.030
Why?
Cytoskeletal Proteins
1
2015
141
0.030
Why?
Ezetimibe
1
2014
26
0.030
Why?
Gene Silencing
1
2015
180
0.030
Why?
Microfilament Proteins
1
2015
130
0.030
Why?
Azetidines
1
2014
40
0.030
Why?
Microscopy, Electron
1
2014
417
0.030
Why?
Apolipoproteins E
1
2014
76
0.030
Why?
Simvastatin
1
2014
62
0.030
Why?
Primary Cell Culture
1
2014
159
0.030
Why?
Gene Expression Profiling
1
2021
1694
0.030
Why?
Actins
1
2016
403
0.030
Why?
Polypyrimidine Tract-Binding Protein
1
2013
16
0.030
Why?
Mitochondria
1
2020
837
0.030
Why?
Isoquinolines
1
2013
41
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p27
1
2013
71
0.030
Why?
Protein Kinase C-delta
1
2013
43
0.030
Why?
Basic Helix-Loop-Helix Transcription Factors
1
2015
245
0.030
Why?
Blood-Retinal Barrier
1
2013
12
0.030
Why?
Calmodulin
2
2006
74
0.030
Why?
Receptor, Notch1
1
2013
62
0.030
Why?
Liver
1
2022
1832
0.030
Why?
AMP-Activated Protein Kinases
1
2014
187
0.030
Why?
Chemokine CCL2
1
2013
122
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2013
114
0.030
Why?
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
1
2013
42
0.030
Why?
Retroviridae
1
1993
96
0.030
Why?
Familial Primary Pulmonary Hypertension
1
2013
197
0.030
Why?
Forkhead Transcription Factors
1
2013
182
0.030
Why?
Rats, Wistar
1
2013
396
0.020
Why?
C-Reactive Protein
1
2014
394
0.020
Why?
Platelet-Derived Growth Factor
1
2012
89
0.020
Why?
Sequence Alignment
2
2004
333
0.020
Why?
Up-Regulation
1
2015
848
0.020
Why?
Mice, Inbred BALB C
1
2015
1230
0.020
Why?
Oncogene Proteins v-rel
3
1997
3
0.020
Why?
Genes, Reporter
2
2004
268
0.020
Why?
Proto-Oncogene Proteins c-rel
3
1996
6
0.020
Why?
Connective Tissue
1
2011
38
0.020
Why?
Chick Embryo
3
1997
130
0.020
Why?
ErbB Receptors
1
1995
601
0.020
Why?
Aorta, Thoracic
2
2007
260
0.020
Why?
Drug Therapy, Combination
1
2014
1020
0.020
Why?
Cell Line, Transformed
2
2002
140
0.020
Why?
Molecular Targeted Therapy
1
2014
381
0.020
Why?
Nerve Tissue Proteins
1
1995
568
0.020
Why?
Inhibitory Concentration 50
1
2011
83
0.020
Why?
Retina
1
2013
277
0.020
Why?
DNA, Viral
1
1993
380
0.020
Why?
Biological Availability
1
2011
129
0.020
Why?
Fluorescent Antibody Technique
1
2011
392
0.020
Why?
Lipids
1
2014
614
0.020
Why?
Treatment Outcome
1
2025
10239
0.020
Why?
Atherosclerosis
1
2014
392
0.020
Why?
MADS Domain Proteins
1
2009
5
0.020
Why?
Cell Adhesion
1
2011
452
0.020
Why?
Neoplasms
1
2004
2426
0.020
Why?
Colorado
1
2019
4443
0.020
Why?
Monocytes
1
2011
553
0.020
Why?
Genetic Predisposition to Disease
1
2017
2270
0.020
Why?
Phospholipase C gamma
1
2008
28
0.020
Why?
Phosphoserine
1
2008
31
0.020
Why?
Protein Structure, Quaternary
1
2008
120
0.020
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2008
86
0.020
Why?
Dopamine Uptake Inhibitors
1
2007
55
0.020
Why?
Brain
1
1999
2592
0.020
Why?
Multiprotein Complexes
1
2008
147
0.020
Why?
Severity of Illness Index
1
2014
2767
0.020
Why?
Nucleus Accumbens
1
2007
128
0.020
Why?
Inositol 1,4,5-Trisphosphate Receptors
1
2006
28
0.020
Why?
Cocaine
1
2007
150
0.020
Why?
Chickens
1
2006
187
0.020
Why?
DNA, Complementary
1
2006
270
0.020
Why?
Reward
1
2007
238
0.020
Why?
United States
1
2022
13975
0.020
Why?
Receptors, Antigen, B-Cell
1
2006
121
0.020
Why?
Nuclear Receptor Subfamily 4, Group A, Member 1
1
2004
12
0.020
Why?
Calcium Channels
1
2006
148
0.020
Why?
DNA
2
2003
1406
0.010
Why?
Receptors, Steroid
1
2004
47
0.010
Why?
Rabbits
1
2006
757
0.010
Why?
Thymus Gland
1
2004
303
0.010
Why?
Fluorescent Antibody Technique, Indirect
1
2003
48
0.010
Why?
Tritium
1
2003
74
0.010
Why?
Infant
1
2017
8994
0.010
Why?
Ventricular Myosins
1
2003
36
0.010
Why?
Calcium-Calmodulin-Dependent Protein Kinase Type 1
1
2002
3
0.010
Why?
Leucine
1
2003
106
0.010
Why?
Phosphotransferases
1
2002
26
0.010
Why?
Endothelial Cells
1
2008
734
0.010
Why?
Emotions
1
2007
536
0.010
Why?
Glycogen Synthase Kinases
1
2002
2
0.010
Why?
Methyltransferases
1
2002
69
0.010
Why?
Oligonucleotide Array Sequence Analysis
1
2004
772
0.010
Why?
Isoproterenol
1
2002
111
0.010
Why?
Glycogen Synthase Kinase 3
1
2002
78
0.010
Why?
Chronic Disease
1
2007
1715
0.010
Why?
Chromosome Mapping
1
2002
503
0.010
Why?
Two-Hybrid System Techniques
1
2001
56
0.010
Why?
Histone-Lysine N-Methyltransferase
1
2002
126
0.010
Why?
Alcohol Oxidoreductases
1
2001
45
0.010
Why?
Thyroid Hormones
1
2000
54
0.010
Why?
Macromolecular Substances
1
2001
212
0.010
Why?
Muscle Fibers, Fast-Twitch
1
2000
10
0.010
Why?
Amino Acid Motifs
1
2001
209
0.010
Why?
Luciferases
1
2000
148
0.010
Why?
Young Adult
1
2016
12286
0.010
Why?
Exons
1
2000
330
0.010
Why?
Expressed Sequence Tags
1
1999
41
0.010
Why?
Organ Specificity
1
2000
296
0.010
Why?
Electric Stimulation
1
2000
266
0.010
Why?
Zinc Fingers
1
1999
43
0.010
Why?
Ligation
1
1999
87
0.010
Why?
Aorta, Abdominal
1
1999
42
0.010
Why?
In Situ Hybridization
1
1999
295
0.010
Why?
Tissue Distribution
1
1999
295
0.010
Why?
Testis
1
1999
143
0.010
Why?
Fetus
1
2003
764
0.010
Why?
Adolescent
1
2017
20197
0.010
Why?
Cloning, Molecular
1
1999
536
0.010
Why?
Mice, Nude
1
2000
680
0.010
Why?
Motor Neurons
1
2000
236
0.010
Why?
Inhibitor of Apoptosis Proteins
1
1997
45
0.010
Why?
Child
1
2017
20824
0.010
Why?
Disease Susceptibility
1
1999
338
0.010
Why?
Proto-Oncogenes
1
1996
29
0.010
Why?
Restriction Mapping
1
1996
77
0.010
Why?
Oligodeoxyribonucleotides
1
1996
138
0.010
Why?
Aorta
1
1999
410
0.010
Why?
src Homology Domains
1
1996
37
0.010
Why?
Sequence Analysis, DNA
1
1999
778
0.010
Why?
Gene Products, tax
1
1995
13
0.010
Why?
Intestinal Mucosa
1
2000
569
0.010
Why?
3T3 Cells
1
1995
151
0.010
Why?
Adaptor Proteins, Vesicular Transport
1
1995
45
0.010
Why?
Tumor Cells, Cultured
1
1996
928
0.010
Why?
Mutagenesis, Site-Directed
1
1995
356
0.010
Why?
Databases, Factual
1
1999
1289
0.010
Why?
Transcription Factor RelB
1
1993
3
0.010
Why?
Cell Transformation, Viral
1
1993
28
0.010
Why?
Antibodies
1
1995
392
0.010
Why?
Birds
1
1993
74
0.010
Why?
Peptide Fragments
1
1996
694
0.010
Why?
Spleen
1
1993
518
0.010
Why?
HIV-1
1
1995
840
0.000
Why?
Gene Expression Regulation, Neoplastic
1
1993
1312
0.000
Why?
McKinsey's Networks
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