Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joaquin Espinosa

Concepts (328)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Down Syndrome
25
2025
472
7.190
Why?
Tumor Suppressor Protein p53
16
2025
511
4.260
Why?
Transcription, Genetic
12
2021
1415
2.160
Why?
Cyclin-Dependent Kinases
7
2022
130
1.980
Why?
Neoplasms
10
2025
2467
1.790
Why?
Transcriptional Activation
6
2023
365
1.640
Why?
Janus Kinase Inhibitors
2
2024
25
1.630
Why?
Chromosomes, Human, Pair 21
2
2024
43
1.540
Why?
Piperidines
2
2024
196
1.460
Why?
Pyrimidines
3
2024
459
1.380
Why?
Proteome
4
2024
443
1.370
Why?
Transcriptome
4
2024
885
1.270
Why?
Interferons
4
2023
194
1.220
Why?
Hypoxia
2
2024
1079
0.980
Why?
Antineoplastic Agents
5
2025
2058
0.960
Why?
Gene Regulatory Networks
2
2021
284
0.950
Why?
Immunoglobulins
1
2025
159
0.910
Why?
Erythropoiesis
1
2024
51
0.900
Why?
Heme
1
2024
77
0.880
Why?
Blood-Brain Barrier
1
2025
128
0.880
Why?
Receptors, Interferon
2
2023
50
0.860
Why?
Gene Expression Regulation, Neoplastic
8
2021
1354
0.820
Why?
Protein Phosphatase 2C
1
2022
15
0.820
Why?
Transcription Factors
9
2023
1649
0.770
Why?
Molecular Targeted Therapy
1
2025
389
0.760
Why?
Blood
1
2022
103
0.750
Why?
Arthritis, Psoriatic
1
2021
20
0.740
Why?
Cell Death
1
2022
354
0.720
Why?
Genes, Tumor Suppressor
1
2021
86
0.710
Why?
Oncogenes
1
2021
113
0.690
Why?
Proto-Oncogene Proteins c-mdm2
6
2025
64
0.690
Why?
Databases, Genetic
1
2021
232
0.670
Why?
Kynurenine
2
2023
108
0.660
Why?
Heart Defects, Congenital
2
2025
755
0.660
Why?
Trisomy
2
2019
77
0.650
Why?
Apoptosis
10
2023
2501
0.640
Why?
Interferon-alpha
2
2020
194
0.640
Why?
Signal Transduction
9
2024
4913
0.630
Why?
Humans
61
2025
129212
0.620
Why?
Tumor Suppressor Proteins
2
2018
317
0.610
Why?
Cyclin-Dependent Kinase 8
6
2022
44
0.610
Why?
Enhancer Elements, Genetic
1
2020
177
0.610
Why?
Metabolome
1
2021
338
0.580
Why?
Genomics
1
2021
715
0.500
Why?
Case-Control Studies
6
2025
3372
0.460
Why?
Cell Proliferation
6
2023
2388
0.460
Why?
Cell Line, Tumor
9
2023
3211
0.460
Why?
Animals
20
2025
35219
0.450
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
3
2024
270
0.430
Why?
Proteomics
4
2025
1061
0.430
Why?
Carcinoma, Squamous Cell
1
2018
623
0.420
Why?
Cyclins
3
2022
89
0.400
Why?
Mice
14
2024
16861
0.400
Why?
Datasets as Topic
2
2022
109
0.370
Why?
Cell Cycle Proteins
4
2023
586
0.350
Why?
RNA Polymerase II
4
2019
317
0.350
Why?
Triple Negative Breast Neoplasms
3
2019
197
0.340
Why?
Adult
9
2025
35464
0.320
Why?
Mediator Complex
3
2022
57
0.310
Why?
Female
19
2025
68600
0.290
Why?
Gene Expression Profiling
3
2024
1705
0.290
Why?
Biomarkers
4
2025
3968
0.290
Why?
Promoter Regions, Genetic
4
2013
1206
0.280
Why?
Proto-Oncogene Proteins
2
2023
637
0.270
Why?
Gene Expression Regulation
3
2012
2543
0.270
Why?
Adolescent
6
2025
20371
0.270
Why?
Cytokines
5
2024
2011
0.260
Why?
Cell Differentiation
2
2024
1899
0.250
Why?
Positive Transcriptional Elongation Factor B
1
2006
29
0.250
Why?
Cyclin-Dependent Kinase Inhibitor p21
4
2009
117
0.250
Why?
Cell Cycle
2
2008
590
0.250
Why?
Lung Neoplasms
1
2018
2339
0.250
Why?
Phosphorylation
4
2022
1710
0.240
Why?
Metabolomics
2
2021
652
0.240
Why?
Male
11
2025
63491
0.240
Why?
Protein Binding
5
2021
2119
0.230
Why?
Hemoglobin SC Disease
1
2023
13
0.220
Why?
Young Adult
4
2025
12396
0.220
Why?
Erythropoietin
1
2024
86
0.210
Why?
Homeodomain Proteins
2
2019
494
0.210
Why?
Oxidative Phosphorylation
1
2024
187
0.210
Why?
Glutamine
1
2023
98
0.210
Why?
Liposarcoma
1
2023
27
0.210
Why?
Cell Line
4
2019
2777
0.210
Why?
Alzheimer Disease
2
2020
517
0.210
Why?
Cyclin C
1
2022
2
0.210
Why?
Eukaryotic Initiation Factor-2
1
2022
27
0.200
Why?
Child, Preschool
4
2025
10507
0.200
Why?
Diabetic Neuropathies
1
2023
96
0.200
Why?
Growth Disorders
1
2022
80
0.200
Why?
Centrosome
2
2022
64
0.200
Why?
Gene Silencing
1
2023
187
0.190
Why?
Cerebellar Neoplasms
1
2023
156
0.190
Why?
DNA-Binding Proteins
3
2016
1443
0.190
Why?
Medulloblastoma
1
2023
198
0.180
Why?
Acetyltransferases
1
2001
22
0.180
Why?
Stress, Physiological
1
2024
413
0.180
Why?
Hematopoiesis
2
2021
183
0.180
Why?
Access to Information
1
2021
47
0.180
Why?
Doxorubicin
3
2007
325
0.180
Why?
Janus Kinase 1
1
2020
24
0.180
Why?
Cilia
2
2022
178
0.180
Why?
Janus Kinase 2
1
2020
32
0.180
Why?
Azetidines
1
2020
40
0.170
Why?
RNA, Messenger
3
2021
2702
0.170
Why?
Models, Biological
1
2008
1718
0.170
Why?
Up-Regulation
2
2021
837
0.170
Why?
Flow Cytometry
2
2019
1156
0.170
Why?
Insulin-Like Growth Factor I
1
2022
307
0.170
Why?
Data Mining
1
2021
110
0.170
Why?
MicroRNAs
2
2018
675
0.170
Why?
Nuclear Proteins
3
2023
663
0.170
Why?
Anemia, Sickle Cell
1
2023
254
0.170
Why?
Quinolinic Acid
1
2019
8
0.170
Why?
Eosinophilic Esophagitis
1
2024
318
0.170
Why?
Child
6
2025
20853
0.170
Why?
Connective Tissue Diseases
1
2020
82
0.170
Why?
Biosynthetic Pathways
1
2019
23
0.160
Why?
Heart Diseases
1
2023
350
0.160
Why?
Indoleamine-Pyrrole 2,3,-Dioxygenase
1
2019
54
0.160
Why?
Protein Domains
2
2017
253
0.160
Why?
Coinfection
1
2020
131
0.150
Why?
Middle Aged
5
2025
31075
0.150
Why?
Mice, Inbred C57BL
5
2020
5408
0.150
Why?
Genome, Human
1
2021
393
0.150
Why?
Calcinosis
1
2020
230
0.150
Why?
Nedd4 Ubiquitin Protein Ligases
1
2018
15
0.150
Why?
SOXB1 Transcription Factors
1
2019
57
0.150
Why?
Transforming Growth Factor beta2
1
2018
35
0.150
Why?
Forkhead Box Protein O3
1
2018
15
0.150
Why?
rhoA GTP-Binding Protein
1
2018
89
0.150
Why?
Epithelial Cells
1
2024
1064
0.150
Why?
TOR Serine-Threonine Kinases
1
2021
395
0.150
Why?
Bacterial Infections
1
2020
235
0.150
Why?
Stem Cell Niche
1
2018
53
0.140
Why?
Inflammation
2
2020
2723
0.140
Why?
Receptor, Notch1
1
2018
61
0.140
Why?
Inpatients
1
2022
465
0.140
Why?
Cell Survival
1
2021
1085
0.140
Why?
Autoimmunity
1
2023
862
0.140
Why?
Hypersensitivity
1
2020
249
0.140
Why?
Binding Sites
3
2014
1249
0.140
Why?
Apoptosis Regulatory Proteins
1
2018
182
0.140
Why?
Leukemia, Biphenotypic, Acute
1
2017
3
0.140
Why?
Hedgehog Proteins
1
2018
188
0.140
Why?
Sulfonamides
1
2020
496
0.130
Why?
Protein Kinase Inhibitors
2
2020
889
0.130
Why?
T-Lymphocytes
2
2022
1928
0.130
Why?
Histidine Kinase
1
2016
34
0.130
Why?
Osteosarcoma
1
2017
72
0.130
Why?
Antigens
1
2018
355
0.130
Why?
Exosomes
1
2017
96
0.130
Why?
Chromatin
4
2016
479
0.130
Why?
Proteolysis
1
2017
165
0.130
Why?
Interferon-gamma
1
2019
769
0.130
Why?
Neoplasm Recurrence, Local
2
2019
959
0.130
Why?
Adenosine Triphosphatases
1
2016
161
0.120
Why?
HCT116 Cells
3
2019
78
0.120
Why?
Colonic Neoplasms
1
2018
243
0.120
Why?
Ribosomal Proteins
1
2015
77
0.120
Why?
Autophagy
1
2018
267
0.120
Why?
Hematopoietic Stem Cells
1
2018
381
0.120
Why?
Disease Models, Animal
2
2023
4049
0.120
Why?
Nerve Tissue Proteins
1
2019
569
0.120
Why?
Phenotype
1
2023
3074
0.120
Why?
Bone Neoplasms
1
2017
231
0.120
Why?
Neoplastic Stem Cells
1
2019
380
0.120
Why?
Azepines
1
2015
89
0.110
Why?
Gene Expression
1
2019
1469
0.110
Why?
Fibroblasts
1
2019
944
0.110
Why?
Repressor Proteins
1
2017
406
0.110
Why?
Carrier Proteins
1
2018
740
0.110
Why?
ets-Domain Protein Elk-1
1
2013
13
0.110
Why?
Acetylation
2
2007
246
0.110
Why?
Mitogens
1
2013
58
0.110
Why?
Disease Progression
1
2021
2622
0.100
Why?
Down-Regulation
1
2015
636
0.100
Why?
Prospective Studies
1
2025
7103
0.100
Why?
Extracellular Signal-Regulated MAP Kinases
1
2013
168
0.100
Why?
Feedback, Physiological
1
2012
77
0.100
Why?
Tumor Cells, Cultured
3
2019
939
0.100
Why?
RNA Stability
1
2012
100
0.100
Why?
Hypertension, Pulmonary
1
2023
1891
0.090
Why?
Protein Structure, Tertiary
2
2006
837
0.090
Why?
Sirtuins
1
2010
39
0.080
Why?
HeLa Cells
3
2013
607
0.080
Why?
Histones
2
2007
588
0.080
Why?
Intracellular Signaling Peptides and Proteins
2
2023
442
0.080
Why?
S Phase
1
2009
75
0.080
Why?
Diabetes Mellitus, Type 2
1
2023
2433
0.080
Why?
Protamine Kinase
1
2008
8
0.080
Why?
Enzyme Activation
2
2008
811
0.080
Why?
Receptors, Thyroid Hormone
1
2008
21
0.080
Why?
Hydroxyurea
2
2023
34
0.070
Why?
RNA
1
2014
883
0.070
Why?
DNA Topoisomerases, Type II
1
2007
43
0.070
Why?
Multiprotein Complexes
1
2008
154
0.070
Why?
Formaldehyde
1
2007
60
0.070
Why?
Genome-Wide Association Study
2
2025
1332
0.070
Why?
Radiation, Ionizing
1
2007
76
0.070
Why?
Glycolysis
2
2024
309
0.070
Why?
Protein Kinases
1
2009
318
0.070
Why?
RNA Precursors
1
2007
147
0.070
Why?
Fluorouracil
1
2007
199
0.060
Why?
Transcription Factors, TFII
1
2006
40
0.060
Why?
High Mobility Group Proteins
1
2006
42
0.060
Why?
Kinetics
2
2007
1641
0.060
Why?
Transcriptional Elongation Factors
1
2006
36
0.060
Why?
Transcription Factor TFIIH
1
2006
40
0.060
Why?
Chromatin Immunoprecipitation
1
2006
132
0.060
Why?
Breast Neoplasms
1
2018
2142
0.060
Why?
Protein Transport
1
2007
425
0.060
Why?
Mice, Knockout
3
2019
2856
0.060
Why?
Serine
1
2006
137
0.060
Why?
Glucose
1
2010
1000
0.060
Why?
Protein Isoforms
1
2006
390
0.060
Why?
Xenograft Model Antitumor Assays
2
2019
813
0.060
Why?
Hemoglobin, Sickle
1
2023
18
0.060
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2006
958
0.050
Why?
Glutamates
1
2023
56
0.050
Why?
Intermediate Filaments
1
2023
27
0.050
Why?
Activating Transcription Factor 4
1
2023
20
0.050
Why?
Proteasome Inhibitors
1
2023
42
0.050
Why?
L-Selectin
1
2023
24
0.050
Why?
Proline
1
2023
76
0.050
Why?
Neurofilament Proteins
1
2023
43
0.050
Why?
Perforin
1
2023
19
0.050
Why?
Tyrosine
1
2023
223
0.050
Why?
Patient Acuity
1
2023
45
0.050
Why?
Proteasome Endopeptidase Complex
1
2023
146
0.050
Why?
Protein Tyrosine Phosphatases
1
2023
168
0.050
Why?
Esophagus
1
2024
248
0.050
Why?
Bile Acids and Salts
1
2023
195
0.050
Why?
Hemolysis
1
2023
199
0.050
Why?
Centrioles
1
2022
41
0.050
Why?
DNA Footprinting
1
2001
33
0.050
Why?
Cytoskeletal Proteins
1
2022
146
0.050
Why?
Neuroimaging
1
2024
279
0.050
Why?
p300-CBP Transcription Factors
1
2001
21
0.050
Why?
Immunoblotting
1
2001
304
0.040
Why?
Clonal Evolution
1
2021
39
0.040
Why?
Histone Acetyltransferases
1
2001
64
0.040
Why?
Germ-Line Mutation
1
2020
140
0.040
Why?
Heterozygote
1
2020
272
0.040
Why?
Toll-Like Receptors
1
2020
179
0.040
Why?
Cells, Cultured
2
2018
4072
0.040
Why?
Interferon Type I
1
2020
139
0.040
Why?
Genetic Testing
1
2022
428
0.040
Why?
Vesiculovirus
1
2019
16
0.040
Why?
Purines
1
2020
171
0.040
Why?
Microtubules
1
2022
262
0.040
Why?
Antigens, Neoplasm
1
2022
309
0.040
Why?
Immunotherapy
1
2024
592
0.040
Why?
Immunotherapy, Adoptive
1
2022
295
0.040
Why?
Drosophila melanogaster
1
2001
214
0.040
Why?
STAT1 Transcription Factor
1
2019
70
0.040
Why?
Heart
1
2023
637
0.040
Why?
Nanog Homeobox Protein
1
2019
13
0.040
Why?
Risk Factors
2
2025
9747
0.040
Why?
DNA
1
2006
1399
0.040
Why?
Myelopoiesis
1
2018
7
0.040
Why?
Lymphopoiesis
1
2018
25
0.040
Why?
Recombinant Fusion Proteins
1
2001
643
0.040
Why?
Mice, 129 Strain
1
2018
86
0.040
Why?
Mice, SCID
1
2019
351
0.040
Why?
MCF-7 Cells
1
2018
116
0.040
Why?
Receptors, Growth Factor
1
2017
55
0.040
Why?
Amyloid beta-Peptides
1
2020
212
0.040
Why?
Polymorphism, Single Nucleotide
1
2025
2071
0.040
Why?
Pyrazoles
1
2020
405
0.030
Why?
Ubiquitin-Conjugating Enzymes
1
2017
13
0.030
Why?
Mice, Inbred NOD
1
2019
588
0.030
Why?
Interleukin-1 Receptor-Associated Kinases
1
2017
27
0.030
Why?
CD8-Positive T-Lymphocytes
1
2023
856
0.030
Why?
Genetic Predisposition to Disease
1
2025
2281
0.030
Why?
CD4-Positive T-Lymphocytes
1
2023
1056
0.030
Why?
Neoplasm Metastasis
1
2019
610
0.030
Why?
Host-Pathogen Interactions
1
2019
352
0.030
Why?
Mitosis
1
2017
179
0.030
Why?
Myeloid-Lymphoid Leukemia Protein
1
2017
71
0.030
Why?
Imidazoles
1
2017
234
0.030
Why?
Mice, Inbred BALB C
1
2019
1243
0.030
Why?
Tumor Protein p73
1
2015
14
0.030
Why?
Cholesterol
1
2017
411
0.030
Why?
Receptors, Estrogen
1
2018
426
0.030
Why?
Histone-Lysine N-Methyltransferase
1
2017
125
0.030
Why?
Aurora Kinase A
1
2015
55
0.030
Why?
Piperazines
1
2017
342
0.030
Why?
Immunity, Innate
1
2020
804
0.030
Why?
Complement System Proteins
1
2017
313
0.030
Why?
Survival Rate
1
2019
1874
0.030
Why?
Cell Movement
1
2018
941
0.030
Why?
Genes, Immediate-Early
1
2013
20
0.030
Why?
Protein Conformation
1
2016
857
0.030
Why?
Genes, ras
1
2013
97
0.030
Why?
NIH 3T3 Cells
1
2013
141
0.030
Why?
B-Lymphocytes
1
2018
815
0.030
Why?
Interleukin-1
1
2017
958
0.030
Why?
Liver
1
2020
1838
0.020
Why?
Biomarkers, Tumor
1
2019
1181
0.020
Why?
Chronic Disease
1
2017
1713
0.020
Why?
HEK293 Cells
1
2013
693
0.020
Why?
Prognosis
1
2019
3791
0.020
Why?
Cell Respiration
1
2010
98
0.020
Why?
Glucose Transporter Type 1
1
2010
49
0.020
Why?
Follow-Up Studies
1
2019
4886
0.020
Why?
Daunorubicin
1
2009
26
0.020
Why?
Checkpoint Kinase 2
1
2009
25
0.020
Why?
Nucleic Acid Synthesis Inhibitors
1
2009
16
0.020
Why?
Checkpoint Kinase 1
1
2009
31
0.020
Why?
Ataxia Telangiectasia Mutated Proteins
1
2009
66
0.020
Why?
Caffeine
1
2009
62
0.020
Why?
Coenzymes
1
2008
18
0.020
Why?
Glyceraldehyde-3-Phosphate Dehydrogenases
1
2007
13
0.020
Why?
RNA Caps
1
2007
31
0.020
Why?
Substrate Specificity
1
2008
368
0.020
Why?
Genes, myc
1
2007
50
0.020
Why?
Poly A
1
2007
48
0.020
Why?
Topoisomerase II Inhibitors
1
2007
24
0.020
Why?
DNA Replication
1
2009
228
0.020
Why?
Gene Expression Regulation, Enzymologic
1
2007
287
0.020
Why?
Retrospective Studies
1
2024
14488
0.020
Why?
Recombinant Proteins
1
2008
1303
0.020
Why?
Mass Spectrometry
1
2008
716
0.010
Why?
Infant
1
2017
9016
0.010
Why?
Myocytes, Cardiac
1
2007
496
0.010
Why?
Mutation
1
2013
3715
0.010
Why?
Models, Molecular
1
2007
1487
0.010
Why?
Espinosa's Networks
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