Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joaquin Espinosa

Concepts (304)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Down Syndrome
18
2023
338
5.100
Why?
Tumor Suppressor Protein p53
14
2023
447
3.600
Why?
Transcription, Genetic
11
2021
1316
2.180
Why?
Cyclin-Dependent Kinases
7
2022
111
2.080
Why?
Transcriptional Activation
6
2023
337
1.700
Why?
Neoplasms
9
2023
2105
1.610
Why?
Proteome
3
2022
339
1.330
Why?
Interferons
4
2023
151
1.310
Why?
Transcriptome
2
2022
727
1.070
Why?
Gene Regulatory Networks
2
2021
228
1.030
Why?
Gene Expression Regulation, Neoplastic
8
2021
1147
0.900
Why?
Receptors, Interferon
2
2023
47
0.880
Why?
Protein Phosphatase 2C
1
2022
14
0.850
Why?
Transcription Factors
8
2023
1528
0.790
Why?
Janus Kinase Inhibitors
1
2021
10
0.780
Why?
Blood
1
2022
96
0.770
Why?
Arthritis, Psoriatic
1
2021
16
0.770
Why?
Cell Death
1
2022
322
0.750
Why?
Genes, Tumor Suppressor
1
2021
77
0.730
Why?
Pyrimidines
2
2021
378
0.720
Why?
Oncogenes
1
2021
107
0.710
Why?
Kynurenine
2
2023
80
0.700
Why?
Databases, Genetic
1
2021
206
0.700
Why?
Piperidines
1
2021
161
0.700
Why?
Trisomy
2
2019
68
0.680
Why?
Chromosomes, Human, Pair 21
1
2019
31
0.670
Why?
Apoptosis
10
2023
2369
0.670
Why?
Interferon-alpha
2
2020
187
0.660
Why?
Tumor Suppressor Proteins
2
2018
282
0.640
Why?
Enhancer Elements, Genetic
1
2020
152
0.640
Why?
Cyclin-Dependent Kinase 8
6
2022
38
0.630
Why?
Metabolome
1
2021
283
0.620
Why?
Antineoplastic Agents
4
2023
1895
0.560
Why?
Heart Defects, Congenital
1
2023
665
0.550
Why?
Genomics
1
2021
639
0.530
Why?
Humans
51
2023
114756
0.510
Why?
Cell Line, Tumor
9
2023
2725
0.500
Why?
Cell Proliferation
6
2023
2196
0.490
Why?
Hypoxia
1
2021
957
0.480
Why?
Proto-Oncogene Proteins c-mdm2
5
2023
56
0.480
Why?
Carcinoma, Squamous Cell
1
2018
584
0.440
Why?
Datasets as Topic
2
2022
98
0.380
Why?
RNA Polymerase II
4
2019
285
0.370
Why?
Animals
17
2023
31761
0.370
Why?
Triple Negative Breast Neoplasms
3
2019
158
0.370
Why?
Mice
13
2023
14916
0.360
Why?
Mediator Complex
3
2022
52
0.320
Why?
Proteomics
3
2023
843
0.310
Why?
Proto-Oncogene Proteins
2
2023
610
0.280
Why?
Signal Transduction
7
2023
4521
0.270
Why?
Case-Control Studies
3
2023
3005
0.270
Why?
Positive Transcriptional Elongation Factor B
1
2006
22
0.260
Why?
Cell Cycle
2
2008
543
0.260
Why?
Gene Expression Regulation
2
2012
2321
0.260
Why?
Lung Neoplasms
1
2018
2199
0.260
Why?
Metabolomics
2
2021
527
0.260
Why?
Phosphorylation
4
2022
1571
0.250
Why?
Cytokines
4
2020
1843
0.240
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
2
2021
249
0.240
Why?
Hemoglobin SC Disease
1
2023
15
0.230
Why?
Cyclins
2
2022
78
0.230
Why?
Alzheimer Disease
2
2020
443
0.220
Why?
Homeodomain Proteins
2
2019
463
0.220
Why?
Liposarcoma
1
2023
26
0.220
Why?
Cell Cycle Proteins
3
2023
552
0.220
Why?
Glutamine
1
2023
91
0.220
Why?
Cell Line
4
2019
2639
0.220
Why?
Protein Binding
4
2021
1896
0.210
Why?
Cyclin-Dependent Kinase Inhibitor p21
3
2009
107
0.210
Why?
Cyclin C
1
2022
2
0.210
Why?
Eukaryotic Initiation Factor-2
1
2022
23
0.210
Why?
Diabetic Neuropathies
1
2023
79
0.210
Why?
Growth Disorders
1
2022
77
0.200
Why?
Centrosome
2
2022
60
0.200
Why?
Biomarkers
3
2023
3416
0.200
Why?
DNA-Binding Proteins
3
2016
1314
0.200
Why?
Cerebellar Neoplasms
1
2023
130
0.200
Why?
Gene Silencing
1
2023
172
0.200
Why?
Medulloblastoma
1
2023
172
0.200
Why?
Doxorubicin
3
2007
286
0.190
Why?
Hematopoiesis
2
2021
172
0.190
Why?
Cilia
2
2022
162
0.190
Why?
Access to Information
1
2021
47
0.180
Why?
Janus Kinase 1
1
2020
23
0.180
Why?
RNA, Messenger
3
2021
2557
0.180
Why?
Janus Kinase 2
1
2020
31
0.180
Why?
MicroRNAs
2
2018
601
0.180
Why?
Models, Biological
1
2008
1630
0.180
Why?
Flow Cytometry
2
2019
1086
0.180
Why?
Azetidines
1
2020
31
0.180
Why?
Insulin-Like Growth Factor I
1
2022
286
0.180
Why?
Anemia, Sickle Cell
1
2023
216
0.180
Why?
Up-Regulation
2
2021
812
0.180
Why?
Nuclear Proteins
3
2023
592
0.180
Why?
Data Mining
1
2021
100
0.180
Why?
Connective Tissue Diseases
1
2020
71
0.170
Why?
Quinolinic Acid
1
2019
7
0.170
Why?
Mice, Inbred C57BL
5
2020
4710
0.170
Why?
Heart Diseases
1
2023
330
0.170
Why?
Biosynthetic Pathways
1
2019
19
0.170
Why?
Indoleamine-Pyrrole 2,3,-Dioxygenase
1
2019
44
0.170
Why?
Gene Expression Profiling
2
2021
1521
0.170
Why?
Protein Domains
2
2017
207
0.170
Why?
Coinfection
1
2020
120
0.160
Why?
Genome, Human
1
2021
351
0.160
Why?
Inflammation
2
2020
2481
0.160
Why?
SOXB1 Transcription Factors
1
2019
61
0.150
Why?
Nedd4 Ubiquitin Protein Ligases
1
2018
13
0.150
Why?
rhoA GTP-Binding Protein
1
2018
73
0.150
Why?
Inpatients
1
2022
378
0.150
Why?
Transforming Growth Factor beta2
1
2018
31
0.150
Why?
Forkhead Box Protein O3
1
2018
13
0.150
Why?
TOR Serine-Threonine Kinases
1
2021
359
0.150
Why?
Stem Cell Niche
1
2018
42
0.150
Why?
Calcinosis
1
2020
242
0.150
Why?
Bacterial Infections
1
2020
219
0.150
Why?
Promoter Regions, Genetic
3
2013
1133
0.150
Why?
Receptor, Notch1
1
2018
61
0.150
Why?
Female
12
2021
59507
0.150
Why?
Cell Survival
1
2021
1021
0.150
Why?
Autoimmunity
1
2023
814
0.150
Why?
T-Lymphocytes
2
2022
1745
0.140
Why?
Adult
5
2021
30548
0.140
Why?
Apoptosis Regulatory Proteins
1
2018
171
0.140
Why?
Sulfonamides
1
2020
445
0.140
Why?
Protein Kinase Inhibitors
2
2020
795
0.140
Why?
Hypersensitivity
1
2020
254
0.140
Why?
Hedgehog Proteins
1
2018
173
0.140
Why?
Leukemia, Biphenotypic, Acute
1
2017
3
0.140
Why?
Antigens
1
2018
318
0.140
Why?
Neoplasm Recurrence, Local
2
2019
863
0.140
Why?
Osteosarcoma
1
2017
67
0.140
Why?
Histidine Kinase
1
2016
33
0.140
Why?
Exosomes
1
2017
91
0.130
Why?
Proteolysis
1
2017
143
0.130
Why?
Interferon-gamma
1
2019
722
0.130
Why?
Disease Models, Animal
2
2023
3542
0.130
Why?
Colonic Neoplasms
1
2018
221
0.130
Why?
Cell Differentiation
1
2023
1699
0.130
Why?
Autophagy
1
2018
233
0.130
Why?
Adenosine Triphosphatases
1
2016
153
0.130
Why?
HCT116 Cells
3
2019
71
0.130
Why?
Ribosomal Proteins
1
2015
70
0.130
Why?
Phenotype
1
2023
2812
0.130
Why?
Hematopoietic Stem Cells
1
2018
345
0.130
Why?
Neoplastic Stem Cells
1
2019
334
0.120
Why?
Bone Neoplasms
1
2017
194
0.120
Why?
Nerve Tissue Proteins
1
2019
529
0.120
Why?
Fibroblasts
1
2019
838
0.120
Why?
Azepines
1
2015
74
0.120
Why?
Repressor Proteins
1
2017
367
0.120
Why?
Gene Expression
1
2019
1420
0.120
Why?
Carrier Proteins
1
2018
696
0.120
Why?
Disease Progression
1
2021
2387
0.110
Why?
ets-Domain Protein Elk-1
1
2013
13
0.110
Why?
Middle Aged
4
2021
26757
0.110
Why?
Mitogens
1
2013
58
0.110
Why?
Down-Regulation
1
2015
596
0.110
Why?
Binding Sites
2
2014
1176
0.110
Why?
Extracellular Signal-Regulated MAP Kinases
1
2013
157
0.100
Why?
Feedback, Physiological
1
2012
68
0.100
Why?
Hypertension, Pulmonary
1
2023
1728
0.100
Why?
Tumor Cells, Cultured
3
2019
854
0.100
Why?
RNA Stability
1
2012
90
0.100
Why?
Chromatin
3
2016
428
0.100
Why?
Diabetes Mellitus, Type 2
1
2023
2097
0.090
Why?
Sirtuins
1
2010
32
0.080
Why?
Intracellular Signaling Peptides and Proteins
2
2023
386
0.080
Why?
Male
5
2021
55579
0.080
Why?
S Phase
1
2009
70
0.080
Why?
Protamine Kinase
1
2008
8
0.080
Why?
Receptors, Thyroid Hormone
1
2008
20
0.080
Why?
Enzyme Activation
2
2008
787
0.080
Why?
Young Adult
2
2021
10463
0.080
Why?
Hydroxyurea
2
2023
30
0.080
Why?
RNA
1
2014
810
0.080
Why?
Formaldehyde
1
2007
46
0.070
Why?
Multiprotein Complexes
1
2008
140
0.070
Why?
DNA Topoisomerases, Type II
1
2007
44
0.070
Why?
Radiation, Ionizing
1
2007
72
0.070
Why?
Protein Kinases
1
2009
307
0.070
Why?
Acetylation
1
2007
211
0.070
Why?
RNA Precursors
1
2007
136
0.070
Why?
Breast Neoplasms
1
2018
1868
0.070
Why?
Fluorouracil
1
2007
152
0.070
Why?
Mice, Knockout
3
2019
2582
0.070
Why?
Kinetics
2
2007
1550
0.070
Why?
Transcription Factors, TFII
1
2006
37
0.070
Why?
Transcription Factor TFIIH
1
2006
34
0.060
Why?
Transcriptional Elongation Factors
1
2006
32
0.060
Why?
High Mobility Group Proteins
1
2006
49
0.060
Why?
Protein Transport
1
2007
396
0.060
Why?
Chromatin Immunoprecipitation
1
2006
129
0.060
Why?
Serine
1
2006
126
0.060
Why?
Glucose
1
2010
897
0.060
Why?
Protein Isoforms
1
2006
339
0.060
Why?
Xenograft Model Antitumor Assays
2
2019
706
0.060
Why?
Hemoglobin, Sickle
1
2023
14
0.060
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2006
928
0.060
Why?
Glutamates
1
2023
58
0.060
Why?
Activating Transcription Factor 4
1
2023
18
0.060
Why?
Proteasome Inhibitors
1
2023
40
0.050
Why?
Protein Structure, Tertiary
1
2006
797
0.050
Why?
Intermediate Filaments
1
2023
46
0.050
Why?
Neurofilament Proteins
1
2023
34
0.050
Why?
Proline
1
2023
72
0.050
Why?
L-Selectin
1
2023
25
0.050
Why?
Perforin
1
2023
19
0.050
Why?
Proteasome Endopeptidase Complex
1
2023
134
0.050
Why?
Tyrosine
1
2023
215
0.050
Why?
Patient Acuity
1
2023
42
0.050
Why?
Protein Tyrosine Phosphatases
1
2023
147
0.050
Why?
Hemolysis
1
2023
146
0.050
Why?
Bile Acids and Salts
1
2023
172
0.050
Why?
Histones
1
2007
536
0.050
Why?
Centrioles
1
2022
35
0.050
Why?
Cytoskeletal Proteins
1
2022
145
0.050
Why?
Clonal Evolution
1
2021
27
0.050
Why?
Immunotherapy, Adoptive
1
2022
184
0.050
Why?
Antigens, Neoplasm
1
2022
222
0.050
Why?
Genetic Testing
1
2022
379
0.040
Why?
Heterozygote
1
2020
251
0.040
Why?
Cells, Cultured
2
2018
3890
0.040
Why?
Microtubules
1
2022
237
0.040
Why?
Germ-Line Mutation
1
2020
130
0.040
Why?
Vesiculovirus
1
2019
9
0.040
Why?
Toll-Like Receptors
1
2020
166
0.040
Why?
Interferon Type I
1
2020
128
0.040
Why?
HeLa Cells
2
2013
562
0.040
Why?
Purines
1
2020
159
0.040
Why?
Heart
1
2023
609
0.040
Why?
STAT1 Transcription Factor
1
2019
65
0.040
Why?
DNA
1
2006
1351
0.040
Why?
Nanog Homeobox Protein
1
2019
11
0.040
Why?
Myelopoiesis
1
2018
6
0.040
Why?
Child
3
2023
18352
0.040
Why?
Lymphopoiesis
1
2018
24
0.040
Why?
Mice, 129 Strain
1
2018
75
0.040
Why?
Mice, SCID
1
2019
320
0.040
Why?
MCF-7 Cells
1
2018
105
0.040
Why?
Amyloid beta-Peptides
1
2020
189
0.040
Why?
CD8-Positive T-Lymphocytes
1
2023
689
0.040
Why?
Receptors, Growth Factor
1
2017
49
0.040
Why?
Pyrazoles
1
2020
364
0.040
Why?
Ubiquitin-Conjugating Enzymes
1
2017
9
0.040
Why?
Mice, Inbred NOD
1
2019
561
0.040
Why?
CD4-Positive T-Lymphocytes
1
2023
965
0.030
Why?
Interleukin-1 Receptor-Associated Kinases
1
2017
20
0.030
Why?
Neoplasm Metastasis
1
2019
528
0.030
Why?
Host-Pathogen Interactions
1
2019
295
0.030
Why?
Genome-Wide Association Study
1
2022
1197
0.030
Why?
Mitosis
1
2017
164
0.030
Why?
Myeloid-Lymphoid Leukemia Protein
1
2017
62
0.030
Why?
Imidazoles
1
2017
211
0.030
Why?
Mice, Inbred BALB C
1
2019
1151
0.030
Why?
Histone-Lysine N-Methyltransferase
1
2017
95
0.030
Why?
Cholesterol
1
2017
368
0.030
Why?
Receptors, Estrogen
1
2018
372
0.030
Why?
Tumor Protein p73
1
2015
14
0.030
Why?
Immunity, Innate
1
2020
723
0.030
Why?
Aurora Kinase A
1
2015
52
0.030
Why?
Piperazines
1
2017
311
0.030
Why?
Complement System Proteins
1
2017
285
0.030
Why?
Survival Rate
1
2019
1642
0.030
Why?
Cell Movement
1
2018
867
0.030
Why?
Genes, Immediate-Early
1
2013
15
0.030
Why?
Protein Conformation
1
2016
811
0.030
Why?
Genes, ras
1
2013
91
0.030
Why?
B-Lymphocytes
1
2018
769
0.030
Why?
NIH 3T3 Cells
1
2013
137
0.030
Why?
Liver
1
2020
1631
0.030
Why?
Adolescent
2
2023
17808
0.030
Why?
Biomarkers, Tumor
1
2019
1053
0.030
Why?
Interleukin-1
1
2017
966
0.030
Why?
Chronic Disease
1
2017
1590
0.020
Why?
HEK293 Cells
1
2013
593
0.020
Why?
Prognosis
1
2019
3334
0.020
Why?
Follow-Up Studies
1
2019
4420
0.020
Why?
Cell Respiration
1
2010
75
0.020
Why?
Glucose Transporter Type 1
1
2010
42
0.020
Why?
Daunorubicin
1
2009
24
0.020
Why?
Checkpoint Kinase 2
1
2009
21
0.020
Why?
Nucleic Acid Synthesis Inhibitors
1
2009
17
0.020
Why?
Checkpoint Kinase 1
1
2009
28
0.020
Why?
Ataxia Telangiectasia Mutated Proteins
1
2009
63
0.020
Why?
Coenzymes
1
2008
16
0.020
Why?
Caffeine
1
2009
57
0.020
Why?
Glycolysis
1
2010
227
0.020
Why?
Glyceraldehyde-3-Phosphate Dehydrogenases
1
2007
14
0.020
Why?
Substrate Specificity
1
2008
354
0.020
Why?
RNA Caps
1
2007
31
0.020
Why?
Genes, myc
1
2007
47
0.020
Why?
DNA Replication
1
2009
205
0.020
Why?
Poly A
1
2007
46
0.020
Why?
Risk Factors
1
2020
8627
0.020
Why?
Topoisomerase II Inhibitors
1
2007
23
0.020
Why?
Gene Expression Regulation, Enzymologic
1
2007
271
0.020
Why?
Mass Spectrometry
1
2008
633
0.020
Why?
Recombinant Proteins
1
2008
1233
0.020
Why?
Infant
1
2017
7935
0.010
Why?
Child, Preschool
1
2017
9079
0.010
Why?
Myocytes, Cardiac
1
2007
448
0.010
Why?
Mutation
1
2013
3350
0.010
Why?
Models, Molecular
1
2007
1378
0.010
Why?
Espinosa's Networks
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