 Chromosomes, Human, Pair 21
"Chromosomes, Human, Pair 21" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific pair of GROUP G CHROMOSOMES of the human chromosome classification.
| Descriptor ID |
D002891
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| MeSH Number(s) |
A11.284.187.520.300.505.510 G05.360.162.520.300.505.510
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chromosomes, Human, Pair 21".
- Anatomy [A]
- Cells [A11]
- Cellular Structures [A11.284]
- Chromosomes [A11.284.187]
- Chromosomes, Mammalian [A11.284.187.520]
- Chromosomes, Human [A11.284.187.520.300]
- Chromosomes, Human, 21-22 and Y [A11.284.187.520.300.505]
- Chromosomes, Human, Pair 21 [A11.284.187.520.300.505.510]
- Biological Sciences [G]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Chromosomes [G05.360.162]
- Chromosomes, Mammalian [G05.360.162.520]
- Chromosomes, Human [G05.360.162.520.300]
- Chromosomes, Human, 21-22 and Y [G05.360.162.520.300.505]
- Chromosomes, Human, Pair 21 [G05.360.162.520.300.505.510]
Below are MeSH descriptors whose meaning is more specific than "Chromosomes, Human, Pair 21".
This graph shows the total number of publications written about "Chromosomes, Human, Pair 21" by people in this website by year, and whether "Chromosomes, Human, Pair 21" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1995 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 2005 | 1 | 2 | 3 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 1 | 2 | | 2020 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Chromosomes, Human, Pair 21" by people in Profiles.
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Rozen EJ, Ozeroff CD, Allen MA. RUN(X) out of blood: emerging RUNX1 functions beyond hematopoiesis and links to Down syndrome. Hum Genomics. 2023 09 05; 17(1):83.
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Bush D, Galambos C, Dunbar Ivy D. Pulmonary hypertension in children with Down syndrome. Pediatr Pulmonol. 2021 03; 56(3):621-629.
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Powers RK, Culp-Hill R, Ludwig MP, Smith KP, Waugh KA, Minter R, Tuttle KD, Lewis HC, Rachubinski AL, Granrath RE, Carmona-Iragui M, Wilkerson RB, Kahn DE, Joshi M, Lle? A, Blesa R, Fortea J, D'Alessandro A, Costello JC, Sullivan KD, Espinosa JM. Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors. Nat Commun. 2019 10 18; 10(1):4766.
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de Smith AJ, Walsh KM, Morimoto LM, Francis SS, Hansen HM, Jeon S, Gonseth S, Chen M, Sun H, Luna-Fineman S, Antill?n F, Gir?n V, Kang AY, Smirnov I, Shao X, Whitehead TP, Barcellos LF, Jolly KW, Healy J, Laverdi?re C, Sinnett D, Taub JW, Birch JM, Thompson PD, Pombo-de-Oliveira MS, Spector LG, DeWan AT, Mueller BA, Chiang C, Metayer C, Ma X, Wiemels JL. Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome. Leukemia. 2019 11; 33(11):2746-2751.
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Gonzales PK, Roberts CM, Fonte V, Jacobsen C, Stein GH, Link CD. Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21. PLoS One. 2018; 13(3):e0194581.
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Ranjitha Dhanasekaran A, Gardiner KJ. RPPAware: A software suite to preprocess, analyze and visualize reverse phase protein array data. J Bioinform Comput Biol. 2018 06; 16(3):1850001.
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Ahmed MM, Block A, Tong S, Davisson MT, Gardiner KJ. Age exacerbates abnormal protein expression in a mouse model of Down syndrome. Neurobiol Aging. 2017 09; 57:120-132.
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Aivazidis S, Coughlan CM, Rauniyar AK, Jiang H, Liggett LA, Maclean KN, Roede JR. The burden of trisomy 21 disrupts the proteostasis network in Down syndrome. PLoS One. 2017; 12(4):e0176307.
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Gupta M, Dhanasekaran AR, Gardiner KJ. Mouse models of Down syndrome: gene content and consequences. Mamm Genome. 2016 12; 27(11-12):538-555.
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Potter H, Granic A, Caneus J. Role of Trisomy 21 Mosaicism in Sporadic and Familial Alzheimer's Disease. Curr Alzheimer Res. 2016; 13(1):7-17.
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