 T-Lymphocytes, Regulatory
"T-Lymphocytes, Regulatory" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
CD4-positive T cells that inhibit immunopathology or autoimmune disease in vivo. They inhibit the immune response by influencing the activity of other cell types. Regulatory T-cells include naturally occurring CD4+CD25+ cells, IL-10 secreting Tr1 cells, and Th3 cells.
| Descriptor ID |
D050378
|
| MeSH Number(s) |
A11.118.637.555.567.550.500.700 A11.118.637.555.567.569.200.700 A11.118.637.555.567.569.500.700 A15.145.229.637.555.567.550.500.700 A15.145.229.637.555.567.569.200.700 A15.145.229.637.555.567.569.500.700 A15.382.490.555.567.550.500.700 A15.382.490.555.567.569.200.700 A15.382.490.555.567.569.500.700
|
| Concept/Terms |
T-Lymphocytes, Regulatory- T-Lymphocytes, Regulatory
- T Lymphocytes, Regulatory
- Regulatory T-Lymphocytes
- Regulatory T Lymphocytes
- Regulatory T-Lymphocyte
- T-Lymphocyte, Regulatory
- Regulatory T-Cells
- Regulatory T Cells
- T-Cells, Regulatory
- T Cells, Regulatory
- Treg Cells
- Cell, Treg
- Cells, Treg
- Treg Cell
Th3 Cells- Th3 Cells
- Cell, Th3
- Cells, Th3
- Th3 Cell
Suppressor T-Lymphocytes, Naturally-Occurring- Suppressor T-Lymphocytes, Naturally-Occurring
- Naturally-Occurring Suppressor T-Lymphocyte
- Naturally-Occurring Suppressor T-Lymphocytes
- Suppressor T Lymphocytes, Naturally Occurring
- Suppressor T-Lymphocyte, Naturally-Occurring
- Suppressor T-Cells, Naturally-Occurring
- Naturally-Occurring Suppressor T-Cell
- Naturally-Occurring Suppressor T-Cells
- Suppressor T Cells, Naturally Occurring
- Suppressor T-Cell, Naturally-Occurring
- T-Cell, Naturally-Occurring Suppressor
- T-Cells, Naturally-Occurring Suppressor
Tr1 Cells- Tr1 Cells
- Cell, Tr1
- Cells, Tr1
- Tr1 Cell
|
Below are MeSH descriptors whose meaning is more general than "T-Lymphocytes, Regulatory".
- Anatomy [A]
- Cells [A11]
- Blood Cells [A11.118]
- Leukocytes [A11.118.637]
- Leukocytes, Mononuclear [A11.118.637.555]
- Lymphocytes [A11.118.637.555.567]
- Lymphocyte Subsets [A11.118.637.555.567.550]
- T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
- T-Lymphocytes, Regulatory [A11.118.637.555.567.550.500.700]
- T-Lymphocytes [A11.118.637.555.567.569]
- CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
- T-Lymphocytes, Regulatory [A11.118.637.555.567.569.200.700]
- T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
- T-Lymphocytes, Regulatory [A11.118.637.555.567.569.500.700]
- Hemic and Immune Systems [A15]
- Blood [A15.145]
- Blood Cells [A15.145.229]
- Leukocytes [A15.145.229.637]
- Leukocytes, Mononuclear [A15.145.229.637.555]
- Lymphocytes [A15.145.229.637.555.567]
- Lymphocyte Subsets [A15.145.229.637.555.567.550]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
- T-Lymphocytes, Regulatory [A15.145.229.637.555.567.550.500.700]
- T-Lymphocytes [A15.145.229.637.555.567.569]
- CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
- T-Lymphocytes, Regulatory [A15.145.229.637.555.567.569.200.700]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
- T-Lymphocytes, Regulatory [A15.145.229.637.555.567.569.500.700]
- Immune System [A15.382]
- Leukocytes [A15.382.490]
- Leukocytes, Mononuclear [A15.382.490.555]
- Lymphocytes [A15.382.490.555.567]
- Lymphocyte Subsets [A15.382.490.555.567.550]
- T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
- T-Lymphocytes, Regulatory [A15.382.490.555.567.550.500.700]
- T-Lymphocytes [A15.382.490.555.567.569]
- CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
- T-Lymphocytes, Regulatory [A15.382.490.555.567.569.200.700]
- T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
- T-Lymphocytes, Regulatory [A15.382.490.555.567.569.500.700]
Below are MeSH descriptors whose meaning is more specific than "T-Lymphocytes, Regulatory".
This graph shows the total number of publications written about "T-Lymphocytes, Regulatory" by people in this website by year, and whether "T-Lymphocytes, Regulatory" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 0 | 1 | | 2005 | 4 | 0 | 4 | | 2006 | 6 | 1 | 7 | | 2007 | 11 | 1 | 12 | | 2008 | 18 | 4 | 22 | | 2009 | 12 | 3 | 15 | | 2010 | 6 | 2 | 8 | | 2011 | 7 | 5 | 12 | | 2012 | 8 | 2 | 10 | | 2013 | 7 | 5 | 12 | | 2014 | 12 | 8 | 20 | | 2015 | 8 | 2 | 10 | | 2016 | 9 | 6 | 15 | | 2017 | 12 | 2 | 14 | | 2018 | 7 | 2 | 9 | | 2019 | 7 | 8 | 15 | | 2020 | 4 | 1 | 5 | | 2021 | 7 | 5 | 12 | | 2022 | 3 | 9 | 12 | | 2023 | 4 | 7 | 11 | | 2024 | 2 | 4 | 6 | | 2025 | 4 | 3 | 7 | | 2026 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "T-Lymphocytes, Regulatory" by people in Profiles.
-
Piper M, Hodgson CA, Gadwa J, Hoen M, Knitz MW, Yu J, Corbo S, Olimpo NA, Yee EJ, Zhu Y, Larson KY, Klein C, Amann M, Saviola AJ, Karam SD. IL15/IL15Ra Complex Induces an Antitumor Immune Response following Radiotherapy only in the Absence of Tregs and Fails to Expand Progenitor TCF1+ CD8 T Cells. Mol Cancer Ther. 2026 Jan 02; 25(1):168-182.
-
Alula KM, Nguyen TT, de Zoeten EF. Regulation of intestinal regulatory T cells via stress response pathways in inflammatory bowel disease. Autoimmunity. 2026 Dec 31; 59(1):2602715.
-
Lanzar ZR, Aldridge DL, Cruz-Morales E, Howard CA, Conway IO, Zhong Z, Eberhard JN, Pereira JA, Phan AT, Ring AM, Parker M, Kanellopoulou C, Min B, Kedl RM, Christian DA, Hunter CA. IL-27 promotes Treg cell expression of CD122 and fitness at homeostasis. Proc Natl Acad Sci U S A. 2025 Dec 16; 122(50):e2519141122.
-
Prawira A, Xu H, Mei Y, Leow WQ, Nasir NJM, Reolo MJ, Otsuka M, Rahbari M, Chen Z, Weerasooriya M, Abdullah LB, Wu J, Hazirah SN, Wasser M, Chung A, Goh BK, Chow PK, Albani S, Lee J, Lim TKH, Zhai W, Dan YY, Goh GB, Heikenwälder MF, Zhang Y, Dasgupta R, Tai WMD, Liu H, Chen J, Chew V. Targeting Treg-fibroblast interaction to enhance immunotherapy in steatotic liver disease-related hepatocellular carcinoma. Gut. 2025 Dec 05; 75(1):105-118.
-
Cabrera-Martinez B, Garcia-Perez JE, Baxter RM, Lui VG, Ghosh T, Eken A, Kostka-Newman Z, Garcia JRM, Rahkola J, Gessner RL, Dutmer CM, Klarquist J, Pietras EM, Ghosh D, Johnson SA, Kedl RM, Hsieh EWY. A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rß deficiency. Cell Rep. 2025 Jul 22; 44(7):115902.
-
Teng KWW, Khoo WH, Ho NCW, Yang SJ, Wilson DC, Chua E, Ho SWS. Diving Deep: Profiling Exhausted T Cells in the Tumor Microenvironment Using Spectral Flow Cytometry. Cytometry A. 2025 Apr; 107(4):271-280.
-
Yamada R, Arima K, Yano H, Fujiwara Y, Yamashita K, Kanemitsu K, Hanada N, Yasunaga JI, Iwatsuki M, Mikami Y, Komohara Y. Impact of HTLV-1 infection on clinicopathological characteristics and tumour immune microenvironment in colorectal cancer. Virchows Arch. 2025 Oct; 487(4):853-863.
-
Johnson MJ, Lazarus SK, Bennett AE, Tovar-Salazar A, Robertson CE, Kofonow JM, Li S, McCollister B, Nunes MC, Madhi SA, Frank DN, Weinberg A. Gut microbiota and other factors associated with increased T cell regulation in HIV-exposed uninfected infants. Front Immunol. 2025; 16:1533003.
-
Gonzalez NM, Zou D, Zeng Z, Feng FX, Zhang X, Sannes C, Gu A, Zu Y, Chen W. Transient Anti-TCRß mAb Treatment Induces CD4 + T Cell Exhaustion and Prolongs Survival in a Mouse Model of Systemic Lupus Erythematosus. Immunology. 2025 02; 174(2):239-246.
-
Peeters JGC, Silveria S, Ozdemir M, Ramachandran S, DuPage M. Hyperactivating EZH2 to augment H3K27me3 levels in regulatory T cells enhances immune suppression by driving early effector differentiation. Cell Rep. 2024 09 24; 43(9):114724.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|