 Nitric Oxide
"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
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| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
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| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
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Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 9 | 1 | 10 | | 1995 | 13 | 6 | 19 | | 1996 | 11 | 1 | 12 | | 1997 | 18 | 7 | 25 | | 1998 | 12 | 5 | 17 | | 1999 | 13 | 7 | 20 | | 2000 | 5 | 2 | 7 | | 2001 | 3 | 3 | 6 | | 2002 | 3 | 7 | 10 | | 2003 | 10 | 4 | 14 | | 2004 | 11 | 9 | 20 | | 2005 | 13 | 15 | 28 | | 2006 | 6 | 6 | 12 | | 2007 | 10 | 15 | 25 | | 2008 | 14 | 14 | 28 | | 2009 | 6 | 13 | 19 | | 2010 | 8 | 11 | 19 | | 2011 | 11 | 12 | 23 | | 2012 | 9 | 11 | 20 | | 2013 | 11 | 9 | 20 | | 2014 | 11 | 13 | 24 | | 2015 | 8 | 10 | 18 | | 2016 | 10 | 8 | 18 | | 2017 | 3 | 5 | 8 | | 2018 | 5 | 7 | 12 | | 2019 | 7 | 11 | 18 | | 2020 | 9 | 10 | 19 | | 2021 | 9 | 7 | 16 | | 2022 | 1 | 12 | 13 | | 2023 | 2 | 9 | 11 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Covar R, Lazarus SC, Krishnan JA, Blake KV, Sorkness CA, Dyer AM, Lang JE, Lugogo NL, Mauger DT, Wechsler ME, Wenzel SE, Cardet JC, Castro M, Israel E, Phipatanakul W, King TS. Association of Sputum Eosinophilia With Easily Measured Type-2 Inflammatory Biomarkers in Untreated Mild Persistent Asthma. J Allergy Clin Immunol Pract. 2024 Apr; 12(4):960-969.e6.
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Garcia VP, Fandl HK, Hijmans JG, Berry AR, Cardenas HL, Stockelman KA, DeSouza NM, Treuth JW, Greiner JJ, Park AJ, Stauffer BL, DeSouza CA. Effects of circulating endothelial microvesicles isolated from adults with obesity on endothelial cell inflammation, apoptosis, and nitric oxide production. Am J Physiol Endocrinol Metab. 2024 01 01; 326(1):E38-E49.
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Moreau KL, Clayton ZS, DuBose LE, Rosenberry R, Seals DR. Effects of regular exercise on vascular function with aging: Does sex matter? Am J Physiol Heart Circ Physiol. 2024 01 01; 326(1):H123-H137.
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Freeberg KA, Ludwig KR, Chonchol M, Seals DR, Rossman MJ. NAD+-boosting compounds enhance nitric oxide production and prevent oxidative stress in endothelial cells exposed to plasma from patients with COVID-19. Nitric Oxide. 2023 Nov 01; 140-141:1-7.
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Clayton ZS, Rossman MJ, Mahoney SA, Venkatasubramanian R, Maurer GS, Hutton DA, VanDongen NS, Greenberg NT, Longtine AG, Ludwig KR, Brunt VE, LaRocca TJ, Campisi J, Melov S, Seals DR. Cellular Senescence Contributes to Large Elastic Artery Stiffening and Endothelial Dysfunction With Aging: Amelioration With Senolytic Treatment. Hypertension. 2023 10; 80(10):2072-2087.
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Li X, Ke Y, Hernandez AL, Yu J, Bian L, Hall SC, Nolan K, Wang JH, Young CD, Wang XJ. Inducible nitric oxide synthase (iNOS)-activated Cxcr2 signaling in myeloid cells promotes TGF?-dependent squamous cell carcinoma lung metastasis. Cancer Lett. 2023 08 28; 570:216330.
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Dyess NF, Palmer C, Soll RF, Clark RH, Abman SH, Kinsella JP. Practices and Outcomes from a Prospective, Multicenter Registry for Preterm Newborns with Pulmonary Hypertension. J Pediatr. 2023 11; 262:113614.
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Cardenas HL, Evanoff NG, Fandl HK, Berry AR, Wegerson KN, Ostrander EI, Greiner JJ, Dufresne SR, Kotlyar M, Dengel DR, DeSouza CA, Garcia VP. Endothelial-derived extracellular vesicles associated with electronic cigarette use impair cerebral microvascular cell function. J Appl Physiol (1985). 2023 08 01; 135(2):271-278.
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Murray KO, Ludwig KR, Darvish S, Coppock ME, Seals DR, Rossman MJ. Chronic mitochondria antioxidant treatment in older adults alters the circulating milieu to improve endothelial cell function and mitochondrial oxidative stress. Am J Physiol Heart Circ Physiol. 2023 07 01; 325(1):H187-H194.
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Nie W, Yan C, Yang L, Roldin P, Liu Y, Vogel AL, Molteni U, Stolzenburg D, Finkenzeller H, Amorim A, Bianchi F, Curtius J, Dada L, Draper DC, Duplissy J, Hansel A, He XC, Hofbauer V, Jokinen T, Kim C, Lehtipalo K, Nichman L, Mauldin RL, Makhmutov V, Mentler B, Mizelli-Ojdanic A, Pet?j? T, Qu?l?ver LLJ, Schallhart S, Simon M, Tauber C, Tom? A, Volkamer R, Wagner AC, Wagner R, Wang M, Ye P, Li H, Huang W, Qi X, Lou S, Liu T, Chi X, Dommen J, Baltensperger U, El Haddad I, Kirkby J, Worsnop D, Kulmala M, Donahue NM, Ehn M, Ding A. NO at low concentration can enhance the formation of highly oxygenated biogenic molecules in the atmosphere. Nat Commun. 2023 Jun 08; 14(1):3347.
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