 RNA Stability
"RNA Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The extent to which an RNA molecule retains its structural integrity and resists degradation by RNASE, and base-catalyzed HYDROLYSIS, under changing in vivo or in vitro conditions.
| Descriptor ID |
D020871
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| MeSH Number(s) |
G02.111.780
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| Concept/Terms |
mRNA Degradation- mRNA Degradation
- Degradation, mRNA
- mRNA Transcript Degradation
- Degradation, mRNA Transcript
- Transcript Degradation, mRNA
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Below are MeSH descriptors whose meaning is more general than "RNA Stability".
Below are MeSH descriptors whose meaning is more specific than "RNA Stability".
This graph shows the total number of publications written about "RNA Stability" by people in this website by year, and whether "RNA Stability" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 3 | 3 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 2 | 3 | | 2006 | 0 | 3 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 2 | 3 | | 2010 | 0 | 2 | 2 | | 2011 | 4 | 1 | 5 | | 2012 | 3 | 4 | 7 | | 2013 | 3 | 1 | 4 | | 2014 | 4 | 4 | 8 | | 2015 | 3 | 5 | 8 | | 2016 | 4 | 6 | 10 | | 2017 | 5 | 3 | 8 | | 2018 | 2 | 3 | 5 | | 2019 | 4 | 1 | 5 | | 2020 | 2 | 2 | 4 | | 2021 | 1 | 3 | 4 | | 2023 | 1 | 2 | 3 | | 2024 | 1 | 3 | 4 | | 2025 | 2 | 4 | 6 | | 2026 | 4 | 0 | 4 |
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Below are the most recent publications written about "RNA Stability" by people in Profiles.
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Gupta A, Struba AZ, Madhavan S, Strayer E, Beaudoin JD. NaP-TRAP: A Versatile and Accessible Workflow to Dissect Principles of Translational Regulation and mRNA Stability. Curr Protoc. 2026 Jul; 6(7):e70417.
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Grijalva-Flores D, Resendiz MJE. Ribonucleobase Oxidation and Ribonucleases Involved in the Degradation of Oxidized RNA. Biomolecules. 2026 Apr 10; 16(4).
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Gu W, Ren Z, Gao J, Shen Z, Wang Y, Xu L, Qian R, Miao Q, Wu Y, Hu X, Wu Y, Liu W, Wan CC, Sun L, Cai Y, Sang M, Zheng C, Yan T. Inhibiting NAT10 suppresses hepatocellular carcinoma progression by reducing Nrf2 mRNA stability and increasing oxidative stress. Chem Biol Interact. 2026 Apr 25; 429:111972.
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Gotthold S, Hansen KR, Brown AN, Chowdhury SP, Joyce CM, Vinish V, Rodriguez SI, Jain S, Ghasemi HI, Yoon AC, Bacal J, Morrissey MA, Gardner BM, Richardson CD. SFPQ Promotes Homologous Recombination via mRNA Stabilization of RAD51 and Its Paralogs. J Mol Biol. 2026 Apr 15; 438(8):169677.
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Moffatt C, Arora A, Vaeth KF, Guzman BB, Bhardwaj G, Hoelscher A, Gifford LB, Russ HA, Dominguez D, Taliaferro JM. TDP-43 directly inhibits mRNA accumulation in neurites through modulation of mRNA stability. EMBO J. 2026 02; 45(3):692-721.
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Lo J, Gifford LB, Vaeth KF, Baldwin A, Bhardwaj G, Goo CEA, Mukherjee N, Russ HA, Moore JK, Taliaferro JM. The RNA-binding protein HNRNPA2B1 regulates neurite RNA abundance and motor-dependent cargo transport. Mol Biol Cell. 2025 Dec 01; 36(12):ar152.
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White LK, Radakovic A, Sajek MP, Dobson K, Riemondy KA, Del Pozo S, Szostak JW, Hesselberth JR. Nanopore sequencing of intact aminoacylated tRNAs. Nat Commun. 2025 Aug 20; 16(1):7781.
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Witt KC, Dziulko A, An J, Pekovic F, Cheng AX, Liu GY, Lee OV, Turner DJ, Lari A, Gaidt MM, Chavez R, Fattinger SA, Abraham P, Dhaliwal H, Lee AY, Kotov DI, Coscoy L, Glaunsinger BA, Valkov E, Chuong EB, Vance RE. SP140-RESIST pathway regulates interferon mRNA stability and antiviral immunity. Nature. 2025 07; 643(8074):1372-1380.
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Palo MZ, Ha B, Lapointe CP, Alvarado C, Janetzko J, Carette JE, Puglisi JD, Puglisi EV. Conserved long-range interactions are required for stable folding of orthoflaviviral genomic RNA. Nucleic Acids Res. 2025 Jun 06; 53(11).
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Forouzanfar F, Moreno DF, Plassard D, Furst A, Oliveira KA, Reina-San-Martin B, Tora L, Molina N, Mendoza M. Gene-specific transcript buffering revealed by perturbation of coactivator complexes. Sci Adv. 2025 Mar 21; 11(12):eadr1492.
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