 RNA Stability
"RNA Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The extent to which an RNA molecule retains its structural integrity and resists degradation by RNASE, and base-catalyzed HYDROLYSIS, under changing in vivo or in vitro conditions.
| Descriptor ID |
D020871
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| MeSH Number(s) |
G02.111.780
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| Concept/Terms |
mRNA Degradation- mRNA Degradation
- Degradation, mRNA
- mRNA Transcript Degradation
- Degradation, mRNA Transcript
- Transcript Degradation, mRNA
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Below are MeSH descriptors whose meaning is more general than "RNA Stability".
Below are MeSH descriptors whose meaning is more specific than "RNA Stability".
This graph shows the total number of publications written about "RNA Stability" by people in this website by year, and whether "RNA Stability" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 3 | 3 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 2 | 3 | | 2006 | 0 | 3 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 2 | 3 | | 2010 | 0 | 2 | 2 | | 2011 | 4 | 1 | 5 | | 2012 | 3 | 4 | 7 | | 2013 | 3 | 1 | 4 | | 2014 | 4 | 4 | 8 | | 2015 | 3 | 5 | 8 | | 2016 | 4 | 6 | 10 | | 2017 | 5 | 3 | 8 | | 2018 | 2 | 3 | 5 | | 2019 | 4 | 1 | 5 | | 2020 | 2 | 2 | 4 | | 2021 | 1 | 3 | 4 | | 2023 | 1 | 2 | 3 | | 2024 | 1 | 3 | 4 | | 2025 | 2 | 4 | 6 |
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Below are the most recent publications written about "RNA Stability" by people in Profiles.
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Moffatt C, Arora A, Vaeth KF, Guzman BB, Bhardwaj G, Hoelscher A, Gifford LB, Russ HA, Dominguez D, Taliaferro JM. TDP-43 directly inhibits mRNA accumulation in neurites through modulation of mRNA stability. EMBO J. 2026 Feb; 45(3):692-721.
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Lo J, Gifford LB, Vaeth KF, Baldwin A, Bhardwaj G, Goo CEA, Mukherjee N, Russ HA, Moore JK, Taliaferro JM. The RNA-binding protein HNRNPA2B1 regulates neurite RNA abundance and motor-dependent cargo transport. Mol Biol Cell. 2025 Dec 01; 36(12):ar152.
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White LK, Radakovic A, Sajek MP, Dobson K, Riemondy KA, Del Pozo S, Szostak JW, Hesselberth JR. Nanopore sequencing of intact aminoacylated tRNAs. Nat Commun. 2025 Aug 20; 16(1):7781.
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Witt KC, Dziulko A, An J, Pekovic F, Cheng AX, Liu GY, Lee OV, Turner DJ, Lari A, Gaidt MM, Chavez R, Fattinger SA, Abraham P, Dhaliwal H, Lee AY, Kotov DI, Coscoy L, Glaunsinger BA, Valkov E, Chuong EB, Vance RE. SP140-RESIST pathway regulates interferon mRNA stability and antiviral immunity. Nature. 2025 07; 643(8074):1372-1380.
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Palo MZ, Ha B, Lapointe CP, Alvarado C, Janetzko J, Carette JE, Puglisi JD, Puglisi EV. Conserved long-range interactions are required for stable folding of orthoflaviviral genomic RNA. Nucleic Acids Res. 2025 Jun 06; 53(11).
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Forouzanfar F, Moreno DF, Plassard D, Furst A, Oliveira KA, Reina-San-Martin B, Tora L, Molina N, Mendoza M. Gene-specific transcript buffering revealed by perturbation of coactivator complexes. Sci Adv. 2025 Mar 21; 11(12):eadr1492.
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Parker DM, Tauber D, Parker R. G3BP1 promotes intermolecular RNA-RNA interactions during RNA condensation. Mol Cell. 2025 Feb 06; 85(3):571-584.e7.
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Miller LG, Kim W, Schowe S, Taylor K, Han R, Jain V, Park R, Sherman M, Fang J, Ramirez H, Ellington A, Tamamis P, Resendiz MJE, Zhang YJ, Contreras L. Selective 8-oxo-rG stalling occurs in the catalytic core of polynucleotide phosphorylase (PNPase) during degradation. Proc Natl Acad Sci U S A. 2024 Nov 12; 121(46):e2317865121.
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Courvan EMC, Parker RR. Hypoxia and inflammation induce synergistic transcriptome turnover in macrophages. Cell Rep. 2024 07 23; 43(7):114452.
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Musaev D, Abdelmessih M, Vejnar CE, Yartseva V, Weiss LA, Strayer EC, Takacs CM, Giraldez AJ. UPF1 regulates mRNA stability by sensing poorly translated coding sequences. Cell Rep. 2024 04 23; 43(4):114074.
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