 Neoplastic Stem Cells
"Neoplastic Stem Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly proliferative, self-renewing, and colony-forming stem cells which give rise to NEOPLASMS.
| Descriptor ID |
D014411
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| MeSH Number(s) |
A11.872.650
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| Concept/Terms |
Neoplastic Stem Cells- Neoplastic Stem Cells
- Cell, Neoplastic Stem
- Cells, Neoplastic Stem
- Neoplastic Stem Cell
- Stem Cell, Neoplastic
- Tumor Stem Cells
- Cell, Tumor Stem
- Cells, Tumor Stem
- Stem Cell, Tumor
- Stem Cells, Tumor
- Tumor Stem Cell
- Tumor Initiating Cells
- Cell, Tumor Initiating
- Cells, Tumor Initiating
- Initiating Cell, Tumor
- Initiating Cells, Tumor
- Tumor Initiating Cell
- Stem Cells, Neoplastic
Cancer Stem Cells- Cancer Stem Cells
- Cancer Stem Cell
- Cell, Cancer Stem
- Cells, Cancer Stem
- Stem Cell, Cancer
- Stem Cells, Cancer
Neoplastic Colony-Forming Units- Neoplastic Colony-Forming Units
- Colony-Forming Unit, Neoplastic
- Neoplastic Colony Forming Units
- Neoplastic Colony-Forming Unit
- Unit, Neoplastic Colony-Forming
- Units, Neoplastic Colony-Forming
- Colony-Forming Units, Neoplastic
- Colony Forming Units, Neoplastic
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Below are MeSH descriptors whose meaning is more general than "Neoplastic Stem Cells".
Below are MeSH descriptors whose meaning is more specific than "Neoplastic Stem Cells".
This graph shows the total number of publications written about "Neoplastic Stem Cells" by people in this website by year, and whether "Neoplastic Stem Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 3 | 0 | 3 | | 2007 | 5 | 1 | 6 | | 2008 | 9 | 0 | 9 | | 2009 | 7 | 1 | 8 | | 2010 | 3 | 3 | 6 | | 2011 | 7 | 2 | 9 | | 2012 | 8 | 1 | 9 | | 2013 | 11 | 2 | 13 | | 2014 | 14 | 6 | 20 | | 2015 | 11 | 3 | 14 | | 2016 | 8 | 3 | 11 | | 2017 | 10 | 3 | 13 | | 2018 | 11 | 2 | 13 | | 2019 | 11 | 5 | 16 | | 2020 | 7 | 5 | 12 | | 2021 | 5 | 5 | 10 | | 2022 | 3 | 4 | 7 | | 2023 | 0 | 4 | 4 | | 2024 | 4 | 0 | 4 | | 2025 | 7 | 1 | 8 |
To return to the timeline, click here.
Below are the most recent publications written about "Neoplastic Stem Cells" by people in Profiles.
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Pawar AS, Somers P, Alex A, Grana J, Feist VK, George SS, Jalnapurkar SS, Antony C, Verner R, White-Brown SK, Khera M, Mendoza-Figueroa MS, Liu KF, Morrissette JJD, Gurbuxani S, Paralkar VR. Leukemia mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness. Genes Dev. 2025 Oct 01; 39(19-20):1219-1240.
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Mulkearns-Hubert EE, Hajdari N, Hong ES, Jacobs AP, Gaboriau A, Giltner S, Tannish G, Kay KE, Wang SZ, LaViolette PS, Silver DJ, Hubert CG, Dhawan A, Lathia JD. Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axis. Cell Rep. 2025 Sep 23; 44(9):116303.
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Zhou X, Moreira S, Restelli C, Wang H, Jahangiri S, Aryal S, Tsao E, Zhang P, Niu M, Kumar H, Balde Z, Vujovic A, Liu L, Wong N, Arruda A, Minden MD, Zhou Y, Ravi B, Qi J, Li C, Hope KJ, Lu R. Activation of a nongenetic AHR-ELMSAN1 axis optimizes BET-targeting therapy and suppresses leukemia stem cells in preclinical models. Sci Transl Med. 2025 Aug 06; 17(810):eadn5400.
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Zheng H, Zhao P, Tan Z, Yu WM, Werner J, Stieglitz E, Porter CC, Chandrakasan S, Wechsler DS, Mendez-Ferrer S, Qu CK. Innate immune mechanisms hijacked by leukemia-initiating stem cells for selective advantage and immune evasion in Ptpn11-associated JMML. Cell Rep. 2025 Aug 26; 44(8):116087.
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Sharma S, Rodems BJ, Baker CD, Kaszuba CM, Franco EI, Smith BR, Ito T, Swovick K, Welle K, Zhang Y, Rock P, Chaves FA, Ghaemmaghami S, Calvi LM, Ganguly A, Burack WR, Becker MW, Liesveld JL, Brookes PS, Munger JC, Jordan CT, Ashton JM, Bajaj J. Taurine from tumour niche drives glycolysis to promote leukaemogenesis. Nature. 2025 Aug; 644(8075):263-272.
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Souto EP, Gong P, Landua JD, Rajaram Srinivasan R, Ganesan A, Dobrolecki LE, Purdy SC, Pan X, Zeosky M, Chung A, Yi SS, Ford HL, Lewis MT. Lineage Tracing and Single-Cell RNA Sequencing Reveal a Common Transcriptional State in Breast Cancer Tumor-Initiating Cells Characterized by IFN/STAT1 Activity. Cancer Res. 2025 Apr 15; 85(8):1390-1409.
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DeSisto J, Balakrishnan I, Knox AJ, Link G, Venkataraman S, Vibhakar R, Green AL. PRMT5 Maintains Tumor Stem Cells to Promote Pediatric High-Grade Glioma Tumorigenesis. Mol Cancer Res. 2025 Feb 06; 23(2):107-118.
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Minhajuddin M, Winters A, Ye H, Pei S, Stevens B, Gillen A, Engel K, Gipson S, Ransom M, Amaya M, Inguva A, Gasparetto M, Althoff MJ, Miller R, Shelton I, Tolison H, Krug A, Culp-Hill R, D'Alessandro A, Sherbenou DW, Pollyea DA, Smith C, Jordan CT. Lysosomal acid lipase A modulates leukemia stem cell response to venetoclax/tyrosine kinase inhibitor combination therapy in blast phase chronic myeloid leukemia. Haematologica. 2025 Jan 01; 110(1):103-116.
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Sheth AI, Althoff MJ, Tolison H, Engel K, Amaya ML, Krug AE, Young TN, Minhajuddin M, Pei S, Patel SB, Winters A, Miller R, Shelton IT, St-Germain J, Ling T, Jones CL, Raught B, Gillen AE, Ransom M, Staggs S, Smith CA, Pollyea DA, Stevens BM, Jordan CT. Targeting Acute Myeloid Leukemia Stem Cells through Perturbation of Mitochondrial Calcium. Cancer Discov. 2024 Oct 04; 14(10):1922-1939.
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Patel SB, Moskop DR, Jordan CT, Pietras EM. Understanding MDS stem cells: Advances and limitations. Semin Hematol. 2024 Dec; 61(6):409-419.
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