 Interferon-gamma
"Interferon-gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
| Descriptor ID |
D007371
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| MeSH Number(s) |
D12.644.276.374.440.893 D12.644.276.374.480.615.350 D12.776.467.374.440.893 D12.776.467.374.480.615.350 D23.529.374.440.893 D23.529.374.480.615.350
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| Concept/Terms |
Interferon-gamma- Interferon-gamma
- gamma-Interferon
- Interferon, Immune
- Immune Interferon
- Type II Interferon
- Interferon, Type II
- Interferon Type II
- Interferon, gamma
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Below are MeSH descriptors whose meaning is more general than "Interferon-gamma".
Below are MeSH descriptors whose meaning is more specific than "Interferon-gamma".
This graph shows the total number of publications written about "Interferon-gamma" by people in this website by year, and whether "Interferon-gamma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 3 | 10 | 13 | | 1997 | 2 | 2 | 4 | | 1998 | 8 | 13 | 21 | | 1999 | 3 | 8 | 11 | | 2000 | 7 | 9 | 16 | | 2001 | 8 | 14 | 22 | | 2002 | 8 | 13 | 21 | | 2003 | 11 | 18 | 29 | | 2004 | 8 | 10 | 18 | | 2005 | 7 | 17 | 24 | | 2006 | 6 | 11 | 17 | | 2007 | 11 | 20 | 31 | | 2008 | 5 | 24 | 29 | | 2009 | 8 | 12 | 20 | | 2010 | 8 | 15 | 23 | | 2011 | 7 | 19 | 26 | | 2012 | 4 | 17 | 21 | | 2013 | 7 | 12 | 19 | | 2014 | 3 | 16 | 19 | | 2015 | 3 | 20 | 23 | | 2016 | 3 | 11 | 14 | | 2017 | 1 | 8 | 9 | | 2018 | 4 | 9 | 13 | | 2019 | 10 | 8 | 18 | | 2020 | 3 | 8 | 11 | | 2021 | 3 | 13 | 16 | | 2022 | 1 | 5 | 6 | | 2023 | 2 | 4 | 6 | | 2024 | 3 | 3 | 6 | | 2025 | 2 | 4 | 6 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interferon-gamma" by people in Profiles.
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Lubkin A, Lujan RA, Pontejo SM, Oikonomou V, Fellows AM, Dos Santos Dias L, Snarr BD, MacAlpine J, Sullivan KD, Espinosa JM, Hickman H, Lionakis MS. The Dp16 Down syndrome mouse model does not exhibit oral interferon-gammopathy or susceptibility to oral candidiasis. mBio. 2026 Mar 11; 17(3):e0387325.
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Huber ME, Larson EA, Lust TN, Heisler CM, Harriff MJ. IFN? regulates MR1 transcription and antigen presentation. Front Immunol. 2025; 16:1624767.
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Ambruso DR, Briones NJ, Tran AD, Sanford B, Childs C, Katz BZ, Ellison M, Johnston RB, Jones KL. Interferon-gamma 1b-induced gene expression alters neutrophil function in patients with chronic granulomatous disease. PLoS One. 2025; 20(9):e0331657.
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Hartsoe P, Schaunaman N, Nichols T, Cervantes D, Dawrs S, Holguin F, Chu HW. Obesity Risk Factors Promote Metabolic Reprogramming and Viral Infection in Airways with Type 1 High Inflammation. Biomolecules. 2025 08 26; 15(9).
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Mann BT, Sanz M, Clohosey ML, Langlands K, Chitrakar A, Moreno-Soriano C, Vitalle J, Iannone MA, Ruiz-Mateos E, Deleage C, Siegel M, Soriano-Sarabia N. Dual role of circulating and mucosal Vd1 T cells in the control of and contribution to persistent HIV-1 infection. Nat Commun. 2025 Jul 01; 16(1):5817.
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Lanzar ZR, Aldridge DL, Jayaraman B, Haskins B, Howard CA, Arana K, Bunkofske ME, Mulka K, Pardy RD, Byerly J, Striepen B, Lupardus P, Hunter CA. De-coupling immune parameters and toxicity associated with IL-12 agonism. Cell Rep. 2025 Jun 24; 44(6):115840.
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Uzen R, Bayram F, Dursun H, Kardas F, Cakir M, Cucer N, Eken A, Donmez-Altuntas H. The number and frequency of mucosal-associated invariant T (MAIT), ?d T, and innate lymphoid cells (ILCs) altered in patients with type I Gaucher disease. Hum Immunol. 2025 May; 86(3):111302.
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Gonzalez NM, Zou D, Zeng Z, Feng FX, Zhang X, Sannes C, Gu A, Zu Y, Chen W. Transient Anti-TCRß mAb Treatment Induces CD4 + T Cell Exhaustion and Prolongs Survival in a Mouse Model of Systemic Lupus Erythematosus. Immunology. 2025 02; 174(2):239-246.
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Sul C, Nozik E, Malainou C. A Tale of Two Cytokines: IL-10 Blocks IFN-? in Influenza A Virus-Staphylococcus aureus Coinfection. Am J Respir Cell Mol Biol. 2024 Jul; 71(1):18-20.
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Cohn IS, Wallbank BA, Haskins BE, O'Dea KM, Pardy RD, Shaw S, Merolle MI, Gullicksrud JA, Christian DA, Striepen B, Hunter CA. Intestinal cDC1s provide cues required for CD4+ T cell-mediated resistance to Cryptosporidium. J Exp Med. 2024 Jul 01; 221(7).
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