 Interferon-gamma
"Interferon-gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
| Descriptor ID |
D007371
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| MeSH Number(s) |
D12.644.276.374.440.893 D12.644.276.374.480.615.350 D12.776.467.374.440.893 D12.776.467.374.480.615.350 D23.529.374.440.893 D23.529.374.480.615.350
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| Concept/Terms |
Interferon-gamma- Interferon-gamma
- gamma-Interferon
- Interferon, Immune
- Immune Interferon
- Type II Interferon
- Interferon, Type II
- Interferon Type II
- Interferon, gamma
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Below are MeSH descriptors whose meaning is more general than "Interferon-gamma".
Below are MeSH descriptors whose meaning is more specific than "Interferon-gamma".
This graph shows the total number of publications written about "Interferon-gamma" by people in this website by year, and whether "Interferon-gamma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1995 | 3 | 3 | 6 | | 1996 | 2 | 10 | 12 | | 1997 | 2 | 2 | 4 | | 1998 | 8 | 13 | 21 | | 1999 | 3 | 8 | 11 | | 2000 | 6 | 7 | 13 | | 2001 | 8 | 14 | 22 | | 2002 | 8 | 14 | 22 | | 2003 | 11 | 18 | 29 | | 2004 | 8 | 9 | 17 | | 2005 | 7 | 18 | 25 | | 2006 | 6 | 11 | 17 | | 2007 | 11 | 18 | 29 | | 2008 | 5 | 24 | 29 | | 2009 | 8 | 12 | 20 | | 2010 | 8 | 15 | 23 | | 2011 | 6 | 18 | 24 | | 2012 | 4 | 17 | 21 | | 2013 | 7 | 10 | 17 | | 2014 | 3 | 16 | 19 | | 2015 | 3 | 18 | 21 | | 2016 | 3 | 11 | 14 | | 2017 | 1 | 8 | 9 | | 2018 | 4 | 9 | 13 | | 2019 | 9 | 6 | 15 | | 2020 | 3 | 8 | 11 | | 2021 | 3 | 12 | 15 | | 2022 | 0 | 6 | 6 | | 2023 | 2 | 1 | 3 | | 2024 | 3 | 3 | 6 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferon-gamma" by people in Profiles.
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Uzen R, Bayram F, Dursun H, Kardas F, Cakir M, Cucer N, Eken A, Donmez-Altuntas H. The number and frequency of mucosal-associated invariant T (MAIT), ?d T, and innate lymphoid cells (ILCs) altered in patients with type I Gaucher disease. Hum Immunol. 2025 May; 86(3):111302.
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Gonzalez NM, Zou D, Zeng Z, Feng FX, Zhang X, Sannes C, Gu A, Zu Y, Chen W. Transient Anti-TCR? mAb Treatment Induces CD4 + T Cell Exhaustion and Prolongs Survival in a Mouse Model of Systemic Lupus Erythematosus. Immunology. 2025 02; 174(2):239-246.
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Sul C, Nozik E, Malainou C. A Tale of Two Cytokines: IL-10 Blocks IFN-? in Influenza A Virus-Staphylococcus aureus Coinfection. Am J Respir Cell Mol Biol. 2024 Jul; 71(1):18-20.
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Cohn IS, Wallbank BA, Haskins BE, O'Dea KM, Pardy RD, Shaw S, Merolle MI, Gullicksrud JA, Christian DA, Striepen B, Hunter CA. Intestinal cDC1s provide cues required for CD4+ T cell-mediated resistance to Cryptosporidium. J Exp Med. 2024 Jul 01; 221(7).
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Pardy RD, Walzer KA, Wallbank BA, Byerly JH, O'Dea KM, Cohn IS, Haskins BE, Roncaioli JL, Smith EJ, Buenconsejo GY, Striepen B, Hunter CA. Analysis of intestinal epithelial cell responses to Cryptosporidium highlights the temporal effects of IFN-? on parasite restriction. PLoS Pathog. 2024 May; 20(5):e1011820.
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Xie W, Bruce K, Belz GT, Farrell HE, Stevenson PG. Indirect CD4+ T cell protection against mouse gamma-herpesvirus infection via interferon gamma. J Virol. 2024 May 14; 98(5):e0049324.
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Haskins BE, Gullicksrud JA, Wallbank BA, Dumaine JE, Gu?rin A, Cohn IS, O'Dea KM, Pardy RD, Merolle MI, Shallberg LA, Hunter EN, Byerly JH, Smith EJ, Buenconsejo GY, McLeod BI, Christian DA, Striepen B, Hunter CA. Dendritic cell-mediated responses to secreted Cryptosporidium effectors promote parasite-specific CD8+ T cell responses. Mucosal Immunol. 2024 Jun; 17(3):387-401.
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Hall CHT, Lanis JM, Dowdell AS, Murphy EM, Bhagavatula G, Neuhart RM, Vijaya Sai KY, Colgan SP. Fundamental role for the creatine kinase pathway in protection from murine colitis. Mucosal Immunol. 2023 12; 16(6):817-825.
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Borko TL, Baxter R, Cabrera-Martinez B, Thiruppathi E, Sabalza M, Venkataraman I, Selva S, Rester C, Sillau S, Pastula DM, Bennett JL, Alvarez E, Gross R, Shah A, Kammeyer R, Corboy JR, Kedl RM, Hsieh EWY, Piquet AL. SARS-CoV-2 mRNA vaccination induces an antigen-specific T cell response correlating with plasma interferon-gamma in B cell depleted patients. J Neuroimmunol. 2023 10 15; 383:578192.
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Horton I, Kelly CJ, Dziulko A, Simpson DM, Chuong EB. Mouse B2 SINE elements function as IFN-inducible enhancers. Elife. 2023 05 09; 12.
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