 Disease Progression
"Disease Progression" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
| Descriptor ID |
D018450
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| MeSH Number(s) |
C23.550.291.656
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| Concept/Terms |
Disease Progression- Disease Progression
- Disease Progressions
- Progression, Disease
- Progressions, Disease
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Below are MeSH descriptors whose meaning is more general than "Disease Progression".
Below are MeSH descriptors whose meaning is more specific than "Disease Progression".
This graph shows the total number of publications written about "Disease Progression" by people in this website by year, and whether "Disease Progression" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 | | 1996 | 0 | 5 | 5 | | 1997 | 0 | 4 | 4 | | 1998 | 0 | 14 | 14 | | 1999 | 0 | 13 | 13 | | 2000 | 0 | 15 | 15 | | 2001 | 0 | 13 | 13 | | 2002 | 0 | 16 | 16 | | 2003 | 0 | 32 | 32 | | 2004 | 0 | 26 | 26 | | 2005 | 0 | 38 | 38 | | 2006 | 1 | 39 | 40 | | 2007 | 2 | 51 | 53 | | 2008 | 2 | 62 | 64 | | 2009 | 4 | 62 | 66 | | 2010 | 4 | 72 | 76 | | 2011 | 7 | 59 | 66 | | 2012 | 3 | 77 | 80 | | 2013 | 6 | 83 | 89 | | 2014 | 6 | 74 | 80 | | 2015 | 8 | 101 | 109 | | 2016 | 8 | 89 | 97 | | 2017 | 9 | 118 | 127 | | 2018 | 8 | 104 | 112 | | 2019 | 11 | 130 | 141 | | 2020 | 3 | 108 | 111 | | 2021 | 9 | 79 | 88 | | 2022 | 0 | 53 | 53 | | 2023 | 2 | 53 | 55 | | 2024 | 30 | 54 | 84 | | 2025 | 6 | 42 | 48 |
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Below are the most recent publications written about "Disease Progression" by people in Profiles.
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Freeberg MAT, Redente EF, Perelas A, Riches DWH, Schwartz DA, Sime PJ. Pulmonary Fibrosis-Focusing on the Future: Aspen Lung Conference 2024 Summary. Am J Respir Cell Mol Biol. 2025 Nov; 73(5):653-667.
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Rieth KKS, Campbell E, Peppone LJ, Netherby-Winslow C, Culakova E, McGuire J, Sun H, Campbell T. Effect of a whole food plant-based dietary intervention on cancer progression and inflammatory markers. Oncologist. 2025 Oct 01; 30(10).
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He Z, Glass MC, Venkatesan P, Feser ML, Lazaro L, Okada LY, Tran NTT, He YD, Zaim SR, Bennett CE, Ravisankar P, Dornisch EM, Ferrannini AC, Arishi NA, Asamoah AG, Barzideh S, Becker LA, Bemis EA, Buckner JH, Collora CE, Criley MAL, Demoruelle MK, Fleischer CL, Garber J, Genge PC, Gong Q, Graybuck LT, Gustafson CE, Hattel BC, Hernandez V, Heubeck AT, Kawelo EK, Krishnan U, Kuan EL, Kuhn KA, LaFrance CM, Lee KJ, Li R, Lord C, Mettey RR, Moss L, Musgrove B, Nguyen KH, Ochoa A, Parthasarathy V, Pebworth MP, Pedrick C, Peng T, Phalen CG, Reading J, Roll CR, Seifert JA, Siedschlag MD, Speake C, Striebich CC, Stuckey TJ, Swanson EG, Takada H, Thai T, Thomson ZJ, Trieu N, Tsaltskan V, Wang W, Weiss MDA, Westermann A, Zhang F, Boyle DL, Goldrath AW, Bumol TF, Li XJ, Holers VM, Skene PJ, Savage AK, Firestein GS, Deane KD, Torgerson TR, Gillespie MA. Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation. Sci Transl Med. 2025 Sep 24; 17(817):eadt7214.
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Savchuk S, Gentry KM, Wang W, Carleton E, Biagi-Junior CAO, Luthria K, Yalçin B, Ni L, Farnsworth HC, Davis RA, Drexler R, Melms JC, Liu Y, Acosta-Alvarez L, Hartmann GG, Pavarino EC, LaBelle J, Woo PJ, Toland AM, Qu F, Kim YS, Filbin MG, Krasnow MA, Ligon KL, Izar B, Sage J, Sabatini BL, Monje M, Venkatesh HS. Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis. Nature. 2025 Oct; 646(8087):1232-1242.
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Smith MJ, Boldison J, Wong FS. The Role of B Lymphocytes in Type 1 Diabetes. Cold Spring Harb Perspect Med. 2025 Sep 02; 15(9).
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Kinghorn B, Mollica F, Caudri D, Davis SD, Dell S, Ferkol TW, Gardner RA, Knowles MR, Milla C, Pittman JE, Rosenfeld M, Sagel SD, Shapiro AJ, Sullivan E, Sullivan KM, Tiddens HAWM, Zariwala MA, Leigh MW. Airway Disease Progression on Chest Computed Tomography in Children With Primary Ciliary Dyskinesia. Pediatr Pulmonol. 2025 Sep; 60(9):e71287.
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Cheng Y, Brokamp C, Manning ER, Kramer EL, Ryan PH, Szczesniak RD, Gecili E. Hypercubes to identify geomarkers of rapid cystic fibrosis lung disease progression. BMC Med Inform Decis Mak. 2025 Aug 13; 25(1):304.
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Barrett A, Maslanka MD, Darula Z, McCabe MC, Saviola AJ, Schmitt LR, Weaver V, Pitts TM, Messersmith WA, Hansen KC. Pancreatic Cancer Progression Involves Increased Lysyl Oxidase-Mediated Collagen Cross-Links as Part of the Desmoplastic Reaction. Biochemistry. 2025 Aug 19; 64(16):3515-3525.
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Sedaka R, Huang J, Yamaguchi S, Hallit E, Moran-Reyna A, Hsu JS, Lovelady C, Fujihashi A, Sako M, Kasztan M, Benavides G, Wilson L, Darley-Usmar V, Barnes S, Saigusa T. Wheat-Based Protein Slows Disease Progression in Pkd1 Knockout Mice. Function (Oxf). 2025 Aug 01; 6(4).
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Lynch AM, Grove NC, Wagner BD, Palestine AG, Holers VM, Frazer-Abel AA, Gnanaraj R, Lisker-Cervantes A, Patnaik JL, de Carlo Forest TE, Auer EA, McReynolds AJ, Mathias MT, Manoharan N, Rodriquez De Cordoba S, Mandava N. Dynamic Risk of Systemic Complement Activation With Time to Progression to Advanced Age-Related Macular Degeneration. JAMA Ophthalmol. 2025 Aug 01; 143(8):634-642.
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