 Cholesterol
"Cholesterol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
| Descriptor ID |
D002784
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| MeSH Number(s) |
D04.210.500.247.222.284 D04.210.500.247.808.197 D10.570.938.208
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cholesterol".
Below are MeSH descriptors whose meaning is more specific than "Cholesterol".
This graph shows the total number of publications written about "Cholesterol" by people in this website by year, and whether "Cholesterol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 3 | 5 | | 1996 | 5 | 3 | 8 | | 1997 | 4 | 0 | 4 | | 1998 | 0 | 4 | 4 | | 1999 | 0 | 5 | 5 | | 2000 | 0 | 6 | 6 | | 2001 | 1 | 4 | 5 | | 2002 | 1 | 3 | 4 | | 2003 | 3 | 12 | 15 | | 2004 | 3 | 6 | 9 | | 2005 | 3 | 9 | 12 | | 2006 | 2 | 2 | 4 | | 2007 | 3 | 7 | 10 | | 2008 | 1 | 8 | 9 | | 2009 | 0 | 9 | 9 | | 2010 | 3 | 8 | 11 | | 2011 | 5 | 5 | 10 | | 2012 | 5 | 2 | 7 | | 2013 | 6 | 14 | 20 | | 2014 | 3 | 7 | 10 | | 2015 | 6 | 10 | 16 | | 2016 | 8 | 7 | 15 | | 2017 | 4 | 6 | 10 | | 2018 | 3 | 5 | 8 | | 2019 | 9 | 8 | 17 | | 2020 | 5 | 3 | 8 | | 2021 | 1 | 4 | 5 | | 2022 | 0 | 13 | 13 | | 2023 | 1 | 8 | 9 | | 2024 | 3 | 5 | 8 | | 2025 | 3 | 2 | 5 |
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Below are the most recent publications written about "Cholesterol" by people in Profiles.
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Chakraborty A, Giraldo-Arias J, Merl-Pham J, Dick E, Mastalerz M, Zöller M, Marchi H, Le Gleut R, Hatz RA, Behr J, Hilgendorff A, Hauck SM, Staab-Weijnitz CA. Cholesterol Regulates Airway Epithelial Cell Differentiation by Inhibiting p53 Nuclear Translocation. Int J Mol Sci. 2025 Aug 27; 26(17).
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Elias ER. The role of cholesterol biosynthesis and metabolism causing medical complexity in patients with Smith-Lemli-Opitz Syndrome (SLOS). J Steroid Biochem Mol Biol. 2025 Nov; 254:106822.
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Mather ML, Evangelou AV, Bourne JN, Macklin WB, Wood TL. Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling. Glia. 2025 Sep; 73(9):1841-1859.
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Safford HC, Shuler CF, Geisler HC, Thatte AS, Swingle KL, Han EL, Murray AM, Hamilton AG, Yamagata HM, Mitchell MJ. Probing the Role of Lipid Nanoparticle Elasticity on mRNA Delivery to the Placenta. Nano Lett. 2025 03 26; 25(12):4800-4808.
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Thibaut MM, Roumain M, Piron E, Gillard J, Loriot A, Neyrinck AM, Rodriguez J, Massart I, Thissen JP, Huot JR, Pin F, Bonetto A, Delzenne NM, Muccioli GG, Bindels LB. The microbiota-derived bile acid taurodeoxycholic acid improves hepatic cholesterol levels in mice with cancer cachexia. Gut Microbes. 2025 Dec; 17(1):2449586.
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Iacono G, Abay A, Murillo JSG, Aglialoro F, Yagci N, Varga E, Bijlsma T, Sohler J, Fu K, Reisz JA, Argabright A, D'Alessandro A, Svendsen AF, von Lindern M, van den Akker E. Differentiating erythroblasts adapt to mechanical stimulation by upregulation of cholesterol biosynthesis via S1P/SREBP-induced HMGCR expression. Sci Rep. 2024 12 04; 14(1):30157.
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Nuotio J, Laitinen TT, Magnussen CG, Sinaiko AR, Bazzano LA, Daniels SR, Jacobs DR, Kartiosuo N, Koskinen J, Burgner DP, K?h?nen M, Raitakari OT, Steinberger J, Urbina EM, Venn AJ, Viikari JSA, Woo JG, Dwyer T, Juonala M. Predictors in Youth of Adult Cardiovascular Events. Pediatrics. 2024 Nov 01; 154(5).
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Ionescu RB, Nicaise AM, Reisz JA, Williams EC, Prasad P, Willis CM, Sim?es-Abade MBC, Sbarro L, Dzieciatkowska M, Stephenson D, Suarez Cubero M, Rizzi S, Pirvan L, Peruzzotti-Jametti L, Fossati V, Edenhofer F, Leonardi T, Frezza C, Mohorianu I, D'Alessandro A, Pluchino S. Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis. Cell Stem Cell. 2024 Nov 07; 31(11):1574-1590.e11.
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Profaci CP, Harvey SS, Bajc K, Zhang TZ, Jeffrey DA, Zhang AZ, Nemec KM, Davtyan H, O'Brien CA, McKinsey GL, Longworth A, McMullen TP, Capocchi JK, Gonzalez JG, Lawson DA, Arnold TD, Davalos D, Blurton-Jones M, Dabertrand F, Bennett FC, Daneman R. Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism. Neuron. 2024 Sep 04; 112(17):2910-2921.e7.
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Wu F, Jacobs DR, Daniels SR, K?h?nen M, Woo JG, Sinaiko AR, Viikari JSA, Bazzano LA, Steinberger J, Urbina EM, Venn AJ, Raitakari OT, Dwyer T, Juonala M, Magnussen CG. Non-High-Density Lipoprotein Cholesterol Levels From Childhood to Adulthood and Cardiovascular Disease Events. JAMA. 2024 06 04; 331(21):1834-1844.
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