 Platelet Activation
"Platelet Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
| Descriptor ID |
D015539
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| MeSH Number(s) |
G09.188.390.600
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| Concept/Terms |
Platelet Activation- Platelet Activation
- Activation, Platelet
- Activations, Platelet
- Platelet Activations
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Below are MeSH descriptors whose meaning is more general than "Platelet Activation".
Below are MeSH descriptors whose meaning is more specific than "Platelet Activation".
This graph shows the total number of publications written about "Platelet Activation" by people in this website by year, and whether "Platelet Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 1 | 2 | 3 | | 1998 | 0 | 2 | 2 | | 1999 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 1 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 3 | 4 | 7 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 2 | 2 | 4 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 2 | 3 | | 2018 | 1 | 2 | 3 | | 2019 | 0 | 1 | 1 | | 2020 | 3 | 0 | 3 | | 2021 | 1 | 0 | 1 | | 2022 | 0 | 2 | 2 | | 2023 | 1 | 2 | 3 | | 2024 | 1 | 3 | 4 | | 2025 | 0 | 3 | 3 | | 2026 | 1 | 2 | 3 |
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Below are the most recent publications written about "Platelet Activation" by people in Profiles.
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Posey JN, Jordan M, Olsen-Dufour A, Nguyen TN, Farrell C, Lewis CV, Archambault JL, Sul C, Colon-Hidalgo D, Nozik ES, Espinosa JM, Sullivan KD, Delaney C. Interferon receptor gene dosage differentially regulates hypoxia-induced platelet activation and pulmonary hypertension in down syndrome. Front Immunol. 2026; 17:1832057.
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Montgomery D, Barrientos ES, Grdadolnik JM, Hendrickson K, Fogelson AL, Neeves KB, Leiderman K. A three-dimensional shear dependent continuum model of platelet aggregation under flow. PLoS Comput Biol. 2026 May; 22(5):e1014241.
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Kanack AJ, Splinter NP, Mauch EE, Tefera L, Gil MR, Jasra S, Goodwin A, Smock KJ, Ahmad H, Ashrani A, Robinson NL, Casanegra AI, Jones CG, Pechauer SM, Yttre E, Aster RH, Kohlhagen MC, Leger RR, Johns G, Murray DL, Zhou L, Wang D, Wen R, Chen D, Pruthi RK, Padmanabhan A. Pathogenic PF4/Polyanion ELISA-Negative Antibodies in HIT. Am J Hematol. 2026 Aug; 101(8):1790-1798.
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Sul C, Lewis CV, Posey J, Jordan M, Colon Hidalgo D, Porfilio T, Elajaili H, McCormack G, Burciaga S, Delaney C, Nozik ES. Increased Circulating Extracellular Superoxide Dismutase Attenuates Platelet-Neutrophil Interactions. Am J Respir Cell Mol Biol. 2025 06; 72(6):653-662.
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Posey JN, Jordan M, Lewis CV, Sul C, Dobrinskikh E, Swindle D, Denorme F, Irwin D, Di Paola J, Stenmark K, Nozik ES, Delaney C. Nbeal2 knockout mice are not protected against hypoxia-induced pulmonary vascular remodeling and pulmonary hypertension. Blood Adv. 2025 Apr 08; 9(7):1571-1584.
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Siska S, Sake C, Neeves KB, Boyle N. Preparation of Washed Human Platelets for Quantitative Metabolic Flux Studies. J Vis Exp. 2025 01 10; (215).
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Kelly K, Kanias T, Leite C, Stanley C, Dumont LJ. Platelet storage in small bags as a model of platelet function in full-sized containers. Transfusion. 2025 Jan; 65(1):185-193.
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Pirabe A, Schrottmaier WC, Mehic D, Hackl H, Frühwirth S, Schmuckenschlager A, Beck S, Gebhart J, Gleixner K, Sperr W, Assinger A. Impaired hemostatic and immune functions of platelets after acute thrombocytopenia. J Thromb Haemost. 2025 Mar; 23(3):1052-1065.
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Mickael C, Jordan M, Posey JN, Tuder RM, Nozik ES, Thurman JM, Stenmark KR, Graham BB, Delaney CA. Activation of platelets and the complement system in mice with Schistosoma-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2024 11 01; 327(5):L661-L668.
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Gallagher LT, LaCroix I, Fields AT, Mitra S, Argabright A, D'Alessandro A, Erickson C, Nunez-Garcia B, Herrera-Rodriguez K, Chou YC, Stocker BW, Ramser BJ, Thielen O, Hallas W, Silliman CC, Kornblith LZ, Cohen MJ. Platelet releasates mitigate the endotheliopathy of trauma. J Trauma Acute Care Surg. 2024 11 01; 97(5):738-746.
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