 Platelet Activation
"Platelet Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
| Descriptor ID |
D015539
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| MeSH Number(s) |
G09.188.390.600
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| Concept/Terms |
Platelet Activation- Platelet Activation
- Activation, Platelet
- Activations, Platelet
- Platelet Activations
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Below are MeSH descriptors whose meaning is more general than "Platelet Activation".
Below are MeSH descriptors whose meaning is more specific than "Platelet Activation".
This graph shows the total number of publications written about "Platelet Activation" by people in this website by year, and whether "Platelet Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 1 | 2 | | 1998 | 0 | 2 | 2 | | 1999 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 1 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 3 | 4 | 7 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 2 | 3 | 5 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 2 | 3 | | 2018 | 1 | 2 | 3 | | 2019 | 0 | 1 | 1 | | 2020 | 3 | 0 | 3 | | 2021 | 1 | 1 | 2 | | 2022 | 0 | 2 | 2 | | 2023 | 1 | 1 | 2 | | 2024 | 1 | 3 | 4 | | 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Platelet Activation" by people in Profiles.
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Posey JN, Jordan M, Lewis CV, Sul C, Dobrinskikh E, Swindle D, Denorme F, Irwin D, Di Paola J, Stenmark K, Nozik ES, Delaney C. Nbeal2 knockout mice are not protected against hypoxia-induced pulmonary vascular remodeling and pulmonary hypertension. Blood Adv. 2025 Apr 08; 9(7):1571-1584.
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Siska S, Sake C, Neeves KB, Boyle N. Preparation of Washed Human Platelets for Quantitative Metabolic Flux Studies. J Vis Exp. 2025 Jan 10; (215).
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Kelly K, Kanias T, Leite C, Stanley C, Dumont LJ. Platelet storage in small bags as a model of platelet function in full-sized containers. Transfusion. 2025 Jan; 65(1):185-193.
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Pirabe A, Schrottmaier WC, Mehic D, Hackl H, Fr?hwirth S, Schmuckenschlager A, Beck S, Gebhart J, Gleixner K, Sperr W, Assinger A. Impaired hemostatic and immune functions of platelets after acute thrombocytopenia. J Thromb Haemost. 2025 Mar; 23(3):1052-1065.
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Mickael C, Jordan M, Posey JN, Tuder RM, Nozik ES, Thurman JM, Stenmark KR, Graham BB, Delaney CA. Activation of platelets and the complement system in mice with Schistosoma-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2024 Nov 01; 327(5):L661-L668.
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Gallagher LT, LaCroix I, Fields AT, Mitra S, Argabright A, D'Alessandro A, Erickson C, Nunez-Garcia B, Herrera-Rodriguez K, Chou YC, Stocker BW, Ramser BJ, Thielen O, Hallas W, Silliman CC, Kornblith LZ, Cohen MJ. Platelet releasates mitigate the endotheliopathy of trauma. J Trauma Acute Care Surg. 2024 Nov 01; 97(5):738-746.
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Michailidou D, Grayson PC, Hermanson P, Chapa JAG, Cuthbertson D, Khalidi NA, Koening CL, Langford CA, McAlear CA, Moreland LW, Pagnoux C, Seo P, Sreih AG, Warrington KJ, Monach PA, Merkel PA, Lood C. Mitochondrial-mediated inflammation and platelet activation in giant cell arteritis. Clin Immunol. 2023 10; 255:109746.
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Nieman MT, Neeves KB. Flipping the script: defining the reversibility of platelet activation. J Thromb Haemost. 2023 05; 21(5):1102-1103.
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Jones WL, Ramos CR, Banerjee A, Moore EE, Hansen KC, Coleman JR, Kelher M, Neeves KB, Silliman CC, Di Paola J, Branchford B. Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength. Platelets. 2022 Nov 17; 33(8):1119-1131.
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Tarandovskiy ID, Buehler PW, Karnaukhova E. C1-inhibitor influence on platelet activation by thrombin receptors agonists. Clin Appl Thromb Hemost. 2022 Jan-Dec; 28:10760296221120422.
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