Glycolysis
"Glycolysis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.
Descriptor ID |
D006019
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MeSH Number(s) |
G02.111.158.750 G03.191.750 G03.295.436 G03.493.360
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Concept/Terms |
Embden-Meyerhof Pathway- Embden-Meyerhof Pathway
- Embden Meyerhof Pathway
- Embden-Meyerhof Pathways
- Pathway, Embden-Meyerhof
- Pathways, Embden-Meyerhof
- Embden-Meyerhof-Parnas Pathway
- Embden Meyerhof Parnas Pathway
- Pathway, Embden-Meyerhof-Parnas
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Below are MeSH descriptors whose meaning is more general than "Glycolysis".
Below are MeSH descriptors whose meaning is more specific than "Glycolysis".
This graph shows the total number of publications written about "Glycolysis" by people in this website by year, and whether "Glycolysis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 2000 | 0 | 1 | 1 | 2003 | 0 | 2 | 2 | 2004 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2006 | 1 | 1 | 2 | 2007 | 2 | 1 | 3 | 2008 | 0 | 1 | 1 | 2009 | 0 | 2 | 2 | 2010 | 0 | 5 | 5 | 2011 | 2 | 3 | 5 | 2012 | 1 | 4 | 5 | 2013 | 0 | 5 | 5 | 2014 | 2 | 1 | 3 | 2015 | 3 | 4 | 7 | 2016 | 3 | 8 | 11 | 2017 | 1 | 9 | 10 | 2018 | 3 | 9 | 12 | 2019 | 1 | 4 | 5 | 2020 | 2 | 6 | 8 | 2021 | 2 | 18 | 20 | 2022 | 0 | 4 | 4 | 2023 | 0 | 6 | 6 | 2024 | 5 | 6 | 11 | 2025 | 2 | 3 | 5 |
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Below are the most recent publications written about "Glycolysis" by people in Profiles.
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Rai M, Li H, Policastro RA, Pepin R, Zentner GE, Nemkov T, D'Alessandro A, Tennessen JM. Glycolytic disruption restricts Drosophila melanogaster larval growth via the cytokine Upd3. PLoS Genet. 2025 May; 21(5):e1011690.
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Prasad RR, Kumar S, Zhang H, Li M, Hu CJ, Riddle S, McKeon BA, Frid MG, Hoetzenecker K, Crnkovic S, Kwapiszewska G, Tuder RM, Stenmark KR. An intracellular complement system drives metabolic and proinflammatory reprogramming of vascular fibroblasts in pulmonary hypertension. JCI Insight. 2025 Feb 13; 10(6).
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Rana NK, Lisk C, Cendali F, Lucero MJ, Grier A, Setua S, Thangaraju K, Khan A, Reisz JA, Dzieciatkowska M, Pak DI, Swindle D, Danaher MX, Khan S, Westover N, Carter M, Hassell K, Nuss R, George G, Buehler PW, D'Alessandro A, Irwin DC. Metabolic and Proteomic Divergence is Present in Spleens and Livers from Berkeley Sickle Cell Anemia and ?-Thalassemia Mice. J Proteome Res. 2025 Mar 07; 24(3):1306-1316.
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Sun X, Yegambaram M, Lu Q, Garcia Flores AE, Pokharel MD, Soto J, Aggarwal S, Wang T, Fineman JR, Black SM. Mitochondrial fission produces a Warburg effect via the oxidative inhibition of prolyl hydroxylase domain-2. Redox Biol. 2025 Apr; 81:103529.
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Heidarian Y, Fasteen TD, Mungcal L, Buddika K, Mahmoudzadeh NH, Nemkov T, D'Alessandro A, Tennessen JM. Hypoxia-inducible factor 1a is required to establish the larval glycolytic program in Drosophila melanogaster. Mol Metab. 2025 Mar; 93:102106.
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Mills TS, Kain B, Burchill MA, Danis E, Lucas ED, Culp-Hill R, Cowan CM, Schleicher WE, Patel SB, Tran BT, Cao R, Goodspeed A, Ferrara S, Bevers S, Jir?n Tamburini BA, Roede JR, D'Alessandro A, King KY, Pietras EM. A distinct metabolic and epigenetic state drives trained immunity in HSC-derived macrophages from autoimmune mice. Cell Stem Cell. 2024 Nov 07; 31(11):1630-1649.e8.
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Ryan S, Crowe L, Almeida Cruz SN, Galbraith MD, O'Brien C, Hammer JA, Bergin R, Kellett SK, Markey GE, Benson TM, Fagan O, Espinosa JM, Conlon N, Donohoe CL, McKiernan S, Hogan AE, McNamee EN, Furuta GT, Menard-Katcher C, Masterson JC. Metabolic dysfunction mediated by HIF-1a contributes to epithelial differentiation defects in eosinophilic esophagitis. J Allergy Clin Immunol. 2024 Dec; 154(6):1472-1488.
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Liu W, Cao H, Wang J, Elmusrati A, Han B, Chen W, Zhou P, Li X, Keysar S, Jimeno A, Wang CY. Histone-methyltransferase KMT2D deficiency impairs the Fanconi anemia/BRCA pathway upon glycolytic inhibition in squamous cell carcinoma. Nat Commun. 2024 Aug 08; 15(1):6755.
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D'Alessandro A, Le K, Lundt M, Li Q, Dunkelberger EB, Cellmer T, Worth AJ, Patil S, Huston C, Grier A, Dzieciatkowska M, Stephenson D, Eaton WA, Thein SL. Functional and multi-omics signatures of mitapivat efficacy upon activation of pyruvate kinase in red blood cells from patients with sickle cell disease. Haematologica. 2024 08 01; 109(8):2639-2652.
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Nemkov T, Stephenson D, Earley EJ, Keele GR, Hay A, Key A, Haiman ZB, Erickson C, Dzieciatkowska M, Reisz JA, Moore A, Stone M, Deng X, Kleinman S, Spitalnik SL, Hod EA, Hudson KE, Hansen KC, Palsson BO, Churchill GA, Roubinian N, Norris PJ, Busch MP, Zimring JC, Page GP, D'Alessandro A. Biological and genetic determinants of glycolysis: Phosphofructokinase isoforms boost energy status of stored red blood cells and transfusion outcomes. Cell Metab. 2024 Sep 03; 36(9):1979-1997.e13.
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