 Genes, Immediate-Early
"Genes, Immediate-Early" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that show rapid and transient expression in the absence of de novo protein synthesis. The term was originally used exclusively for viral genes where immediate-early referred to transcription immediately following virus integration into the host cell. It is also used to describe cellular genes which are expressed immediately after resting cells are stimulated by extracellular signals such as growth factors and neurotransmitters.
| Descriptor ID |
D017781
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| MeSH Number(s) |
G05.360.340.024.340.330 G05.360.340.024.340.364.875.345 G05.360.340.358.024.875.345 G05.360.340.358.840.500.345
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| Concept/Terms |
Genes, Immediate-Early- Genes, Immediate-Early
- Genes, Immediate Early
- Immediate-Early Genes
- Gene, Immediate-Early
- Immediate Early Genes
- Immediate-Early Gene
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Below are MeSH descriptors whose meaning is more general than "Genes, Immediate-Early".
- Biological Sciences [G]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Genome [G05.360.340]
- Genome Components [G05.360.340.024]
- Genes [G05.360.340.024.340]
- Genes, Immediate-Early [G05.360.340.024.340.330]
- Genes, Microbial [G05.360.340.024.340.364]
- Genes, Viral [G05.360.340.024.340.364.875]
- Genes, Immediate-Early [G05.360.340.024.340.364.875.345]
- Genome, Microbial [G05.360.340.358]
- Genes, Microbial [G05.360.340.358.024]
- Genes, Viral [G05.360.340.358.024.875]
- Genes, Immediate-Early [G05.360.340.358.024.875.345]
- Genome, Viral [G05.360.340.358.840]
- Genes, Viral [G05.360.340.358.840.500]
- Genes, Immediate-Early [G05.360.340.358.840.500.345]
Below are MeSH descriptors whose meaning is more specific than "Genes, Immediate-Early".
This graph shows the total number of publications written about "Genes, Immediate-Early" by people in this website by year, and whether "Genes, Immediate-Early" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 | | 1998 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2004 | 1 | 2 | 3 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Genes, Immediate-Early" by people in Profiles.
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Chastain-Potts SE, Tesic V, Tat QL, Cabrera OH, Quillinan N, Jevtovic-Todorovic V. Sevoflurane Exposure Results in Sex-Specific Transgenerational Upregulation of Target IEGs in the Subiculum. Mol Neurobiol. 2020 Jan; 57(1):11-22.
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Cruz FC, Koya E, Guez-Barber DH, Bossert JM, Lupica CR, Shaham Y, Hope BT. New technologies for examining the role of neuronal ensembles in drug addiction and fear. Nat Rev Neurosci. 2013 Nov; 14(11):743-54.
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Galbraith MD, Saxton J, Li L, Shelton SJ, Zhang H, Espinosa JM, Shaw PE. ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1. Nucleic Acids Res. 2013 Dec; 41(22):10241-53.
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Goodwin TJ, McCarthy M, Osterrieder N, Cohrs RJ, Kaufer BB. Three-dimensional normal human neural progenitor tissue-like assemblies: a model of persistent varicella-zoster virus infection. PLoS Pathog. 2013; 9(8):e1003512.
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Adamik J, Wang KZ, Unlu S, Su AJ, Tannahill GM, Galson DL, O'Neill LA, Auron PE. Distinct mechanisms for induction and tolerance regulate the immediate early genes encoding interleukin 1? and tumor necrosis factor a. PLoS One. 2013; 8(8):e70622.
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Fadel HJ, Saenz DT, Poeschla EM. Construction and testing of orfA +/- FIV reporter viruses. Viruses. 2012 01; 4(1):184-99.
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Guez-Barber D, Fanous S, Golden SA, Schrama R, Koya E, Stern AL, Bossert JM, Harvey BK, Picciotto MR, Hope BT. FACS identifies unique cocaine-induced gene regulation in selectively activated adult striatal neurons. J Neurosci. 2011 Mar 16; 31(11):4251-9.
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Bottjer SW, Alderete TL, Chang D. Conjunction of vocal production and perception regulates expression of the immediate early gene ZENK in a novel cortical region of songbirds. J Neurophysiol. 2010 Apr; 103(4):1833-42.
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Zeier Z, Aguilar JS, Lopez CM, Devi-Rao GB, Watson ZL, Baker HV, Wagner EK, Bloom DC. A limited innate immune response is induced by a replication-defective herpes simplex virus vector following delivery to the murine central nervous system. J Neurovirol. 2009 Sep; 15(5-6):411-24.
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Stern JL, Cao JZ, Xu J, Mocarski ES, Slobedman B. Repression of human cytomegalovirus major immediate early gene expression by the cellular transcription factor CCAAT displacement protein. Virology. 2008 Sep 01; 378(2):214-25.
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