 Epilepsy
"Epilepsy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Descriptor ID |
D004827
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| MeSH Number(s) |
C10.228.140.490
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| Concept/Terms |
Epilepsy- Epilepsy
- Epilepsies
- Seizure Disorder
- Seizure Disorders
Epilepsy, Cryptogenic- Epilepsy, Cryptogenic
- Cryptogenic Epilepsies
- Cryptogenic Epilepsy
- Epilepsies, Cryptogenic
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Below are MeSH descriptors whose meaning is more general than "Epilepsy".
Below are MeSH descriptors whose meaning is more specific than "Epilepsy".
This graph shows the total number of publications written about "Epilepsy" by people in this website by year, and whether "Epilepsy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 2 | 0 | 2 | | 1999 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 2 | 1 | 3 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 1 | 2 | | 2005 | 2 | 0 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 1 | 2 | | 2008 | 5 | 2 | 7 | | 2009 | 3 | 0 | 3 | | 2010 | 5 | 1 | 6 | | 2011 | 5 | 0 | 5 | | 2012 | 8 | 1 | 9 | | 2013 | 2 | 2 | 4 | | 2014 | 7 | 1 | 8 | | 2015 | 7 | 1 | 8 | | 2016 | 7 | 3 | 10 | | 2017 | 13 | 1 | 14 | | 2018 | 13 | 2 | 15 | | 2019 | 15 | 4 | 19 | | 2020 | 14 | 1 | 15 | | 2021 | 17 | 2 | 19 | | 2022 | 16 | 2 | 18 | | 2023 | 23 | 0 | 23 | | 2024 | 14 | 6 | 20 | | 2025 | 3 | 1 | 4 |
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Below are the most recent publications written about "Epilepsy" by people in Profiles.
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Kushner JK, Hoffman PB, Brzezinski CR, Svalina MN, O'Neill BR, Hankinson TC, Wilkinson CC, Handler MH, Baca SM, Huntsman MM, Alexander AL. Characterizing the Diversity of Layer 2/3 Human Neocortical Neurons in Pediatric Epilepsy. eNeuro. 2025 May; 12(5).
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Elder C, Pellinen J, Terman SW. The Epilepsy Drug Pipeline: Update on Near-to-Market Therapies. Semin Neurol. 2025 Apr; 45(2):287-297.
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Satzer D, Kaye LC, Ojemann SG, Kramer DR, Thompson JA. Aperiodic activity as a biomarker of seizures and neuromodulation. Brain Stimul. 2025 May-Jun; 18(3):738-744.
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Abreo TJ, Thompson EC, Madabushi A, Park KL, Soh H, Varghese N, Vanoye CG, Springer K, Johnson J, Sims S, Ji Z, Chavez AG, Jankovic MJ, Habte B, Zuberi AR, Lutz CM, Wang Z, Krishnan V, Dudler L, Einsele-Scholz S, Noebels JL, George AL, Maheshwari A, Tzingounis A, Cooper EC. Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy. Elife. 2025 Jan 06; 13.
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Zhou Y, Kobau R, Pastula DM, Greenlund KJ. Comorbidity Among Adults With Epilepsy - United States, 2021-2022. Prev Chronic Dis. 2024 Dec 19; 21:E100.
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Pauly K, Woontner M, Abdenur JE, Chaudhari BP, Gosselin R, Kripps KA, Thomas JA, Wempe MF, Gospe SM, Coughlin CR. Feasibility of newborn screening for pyridoxine-dependent epilepsy. Mol Genet Metab. 2025 Jan; 144(1):109002.
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Wheless JW, Raskin JS, Fine AL, Knupp KG, Schreiber J, Ostendorf AP, Albert GW, Kossoff EH, Madsen JR, Kotagal P, Numis AL, Gadgil N, Holder DL, Thiele EA, Ibrahim GM. Expert opinion on use of vagus nerve stimulation therapy in the management of pediatric epilepsy: A Delphi consensus study. Seizure. 2024 Dec; 123:97-103.
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Perinelli MG, Abbott M, Balagura G, Riva A, Amadori E, Verrotti A, Demarest S, Striano P. Prevalence of cerebral visual impairment in developmental and Epileptic Encephalopathies: a systematic review protocol. Syst Rev. 2024 Aug 31; 13(1):223.
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Sajatovic M, Beem Jelley P, Schrag K, Varanese P, Needham K, Black J, Adeniyi C, Barigye R, Yala J, Ghearing GR, Glasgow RE, Briggs F. A case study in science-to-service application of epilepsy self-management. Epilepsy Behav. 2024 Oct; 159:109945.
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LaFlamme CW, Rastin C, Sengupta S, Pennington HE, Russ-Hall SJ, Schneider AL, Bonkowski ES, Almanza Fuerte EP, Allan TJ, Zalusky MP, Goffena J, Gibson SB, Nyaga DM, Lieffering N, Hebbar M, Walker EV, Darnell D, Olsen SR, Kolekar P, Djekidel MN, Rosikiewicz W, McConkey H, Kerkhof J, Levy MA, Relator R, Lev D, Lerman-Sagie T, Park KL, Alders M, Cappuccio G, Chatron N, Demain L, Genevieve D, Lesca G, Roscioli T, Sanlaville D, Tedder ML, Gupta S, Jones EA, Weisz-Hubshman M, Ketkar S, Dai H, Worley KC, Rosenfeld JA, Chao HT, Neale G, Carvill GL, Wang Z, Berkovic SF, Sadleir LG, Miller DE, Scheffer IE, Sadikovic B, Mefford HC. Diagnostic utility of DNA methylation analysis in genetically unsolved pediatric epilepsies and CHD2 episignature refinement. Nat Commun. 2024 Aug 06; 15(1):6524.
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