 Epilepsy
"Epilepsy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Descriptor ID |
D004827
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| MeSH Number(s) |
C10.228.140.490
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| Concept/Terms |
Epilepsy- Epilepsy
- Epilepsies
- Seizure Disorder
- Seizure Disorders
Epilepsy, Cryptogenic- Epilepsy, Cryptogenic
- Cryptogenic Epilepsies
- Cryptogenic Epilepsy
- Epilepsies, Cryptogenic
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Below are MeSH descriptors whose meaning is more general than "Epilepsy".
Below are MeSH descriptors whose meaning is more specific than "Epilepsy".
This graph shows the total number of publications written about "Epilepsy" by people in this website by year, and whether "Epilepsy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 2 | 0 | 2 | | 1999 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 2 | 1 | 3 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 2 | 3 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 1 | 2 | | 2007 | 1 | 1 | 2 | | 2008 | 4 | 2 | 6 | | 2009 | 3 | 1 | 4 | | 2010 | 4 | 1 | 5 | | 2011 | 6 | 0 | 6 | | 2012 | 7 | 1 | 8 | | 2013 | 1 | 2 | 3 | | 2014 | 8 | 1 | 9 | | 2015 | 7 | 2 | 9 | | 2016 | 7 | 3 | 10 | | 2017 | 12 | 1 | 13 | | 2018 | 12 | 2 | 14 | | 2019 | 15 | 4 | 19 | | 2020 | 15 | 1 | 16 | | 2021 | 18 | 2 | 20 | | 2022 | 17 | 2 | 19 | | 2023 | 25 | 0 | 25 | | 2024 | 14 | 6 | 20 | | 2025 | 5 | 2 | 7 |
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Below are the most recent publications written about "Epilepsy" by people in Profiles.
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Teoh J, Simko J, Camp CR, Liu CJ, Wang W, Williams DJ, Ma L, Soundararajan D, Martin C, Taylor NK, François E, Petri S, Kanber A, Ravichandra A, Pero ME, Bartolini F, Swayne TC, Lutz CM, Zuberi A, Rubinstein M, Hausman-Kedem M, Yuan H, Gelinas JN, Sands TT, Harper SQ, Traynelis SF, Makinson CD, Frankel WN. Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy. Brain. 2025 Nov 04; 148(11):3973-3988.
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Rhodes C, Rees B, Dubbs H, Lesser M, Morgan L, Benke TA, Percy A, Neul JL, Marsh ED. Natural history of epilepsy in FOXG1 Syndrome. Epilepsy Res. 2025 Dec; 218:107644.
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Gibson EA, Restrepo D. Highly sensitive TEMPO imaging illuminates the cellular basis of oscillations in the local field potential. Neuron. 2025 Aug 06; 113(15):2380-2381.
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Cuillerier A, Goodman A, Lawrence C, Villeneuve-Cloutier N, Armour CM, Bhola PT, Bourque DK, Carter MT, Lazier J, Sawyer SL, Saleh M, Prasad C, Siu VM, Boycott KM, Hartley T, Dyment DA, Balci TB. Diagnostic Utility of Exome Data Reanalysis After In Silico Multi-Gene Panels or Clinical Exome Testing for Patients With Epilepsy and Developmental Delay/Intellectual Disability: A Retrospective Cohort Study. Clin Genet. 2026 Jan; 109(1):40-49.
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Kushner JK, Hoffman PB, Brzezinski CR, Svalina MN, O'Neill BR, Hankinson TC, Wilkinson CC, Handler MH, Baca SM, Huntsman MM, Alexander AL. Characterizing the Diversity of Layer 2/3 Human Neocortical Neurons in Pediatric Epilepsy. eNeuro. 2025 May; 12(5).
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Elder C, Pellinen J, Terman SW. The Epilepsy Drug Pipeline: Update on Near-to-Market Therapies. Semin Neurol. 2025 Apr; 45(2):287-297.
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Satzer D, Kaye LC, Ojemann SG, Kramer DR, Thompson JA. Aperiodic activity as a biomarker of seizures and neuromodulation. Brain Stimul. 2025 May-Jun; 18(3):738-744.
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Abreo TJ, Thompson EC, Madabushi A, Park KL, Soh H, Varghese N, Vanoye CG, Springer K, Johnson J, Sims S, Ji Z, Chavez AG, Jankovic MJ, Habte B, Zuberi AR, Lutz CM, Wang Z, Krishnan V, Dudler L, Einsele-Scholz S, Noebels JL, George AL, Maheshwari A, Tzingounis A, Cooper EC. Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy. Elife. 2025 Jan 06; 13.
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Zhou Y, Kobau R, Pastula DM, Greenlund KJ. Comorbidity Among Adults With Epilepsy - United States, 2021-2022. Prev Chronic Dis. 2024 Dec 19; 21:E100.
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Pauly K, Woontner M, Abdenur JE, Chaudhari BP, Gosselin R, Kripps KA, Thomas JA, Wempe MF, Gospe SM, Coughlin CR. Feasibility of newborn screening for pyridoxine-dependent epilepsy. Mol Genet Metab. 2025 Jan; 144(1):109002.
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