 Hematopoietic Stem Cells
"Hematopoietic Stem Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Progenitor cells from which all blood cells derived. They are found primarily in the bone marrow and also in small numbers in the peripheral blood.
| Descriptor ID |
D006412
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| MeSH Number(s) |
A11.148.378 A11.872.378 A15.378.316.378
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| Concept/Terms |
Hematopoietic Stem Cells- Hematopoietic Stem Cells
- Progenitor Cells, Hematopoietic
- Hematopoietic Progenitor Cells
- Cell, Hematopoietic Progenitor
- Cells, Hematopoietic Progenitor
- Hematopoietic Progenitor Cell
- Progenitor Cell, Hematopoietic
- Stem Cells, Hematopoietic
- Cell, Hematopoietic Stem
- Cells, Hematopoietic Stem
- Hematopoietic Stem Cell
- Stem Cell, Hematopoietic
Colony-Forming Units, Hematopoietic- Colony-Forming Units, Hematopoietic
- Colony Forming Units, Hematopoietic
- Colony-Forming Unit, Hematopoietic
- Hematopoietic Colony-Forming Unit
- Hematopoietic Colony-Forming Units
- Unit, Hematopoietic Colony-Forming
- Units, Hematopoietic Colony-Forming
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Below are MeSH descriptors whose meaning is more general than "Hematopoietic Stem Cells".
Below are MeSH descriptors whose meaning is more specific than "Hematopoietic Stem Cells".
This graph shows the total number of publications written about "Hematopoietic Stem Cells" by people in this website by year, and whether "Hematopoietic Stem Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 1 | 6 | | 1996 | 7 | 1 | 8 | | 1997 | 3 | 2 | 5 | | 1998 | 2 | 1 | 3 | | 1999 | 3 | 3 | 6 | | 2000 | 3 | 0 | 3 | | 2001 | 6 | 2 | 8 | | 2002 | 5 | 4 | 9 | | 2003 | 5 | 2 | 7 | | 2004 | 6 | 3 | 9 | | 2005 | 3 | 4 | 7 | | 2006 | 4 | 3 | 7 | | 2007 | 6 | 2 | 8 | | 2008 | 3 | 2 | 5 | | 2009 | 8 | 2 | 10 | | 2010 | 5 | 1 | 6 | | 2011 | 13 | 9 | 22 | | 2012 | 4 | 1 | 5 | | 2013 | 11 | 4 | 15 | | 2014 | 12 | 3 | 15 | | 2015 | 4 | 4 | 8 | | 2016 | 6 | 5 | 11 | | 2017 | 3 | 5 | 8 | | 2018 | 7 | 3 | 10 | | 2019 | 8 | 2 | 10 | | 2020 | 7 | 6 | 13 | | 2021 | 11 | 5 | 16 | | 2022 | 3 | 4 | 7 | | 2023 | 6 | 2 | 8 | | 2024 | 5 | 5 | 10 | | 2025 | 10 | 3 | 13 |
To return to the timeline, click here.
Below are the most recent publications written about "Hematopoietic Stem Cells" by people in Profiles.
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Crowley SJ, Yang W, White LS, Wu J, Li Y, Schmidt H, Choi K, Magee JA, Bednarski JJ. BCLAF1 restrains stress responses in hematopoietic stem cells to support expansion and repopulation. Blood Adv. 2025 Aug 12; 9(15):4043-4057.
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Libby AE, Sullivan TM, Maltzahn JK, Jackman MR, Gavin KM, MacLean PS, Kohrt WM, Majka SM, Klemm DJ. Hematopoietic stem cell-derived adipocytes suppress leptin production, and attenuate ovariectomy-induced inhibition of physical activity and insulin sensitivity in female mice. Adipocyte. 2025 Dec; 14(1):2536813.
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Cowan CM, Pietras EM. From symbiote to bad neighbor: The intestinal microbiome as a driver of CHIP. Cell Stem Cell. 2025 Jul 03; 32(7):1036-1037.
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Kirmani S, Huan T, Van Amburg JC, Joehanes R, Uddin MM, Nguyen NQH, Yu B, Brody JA, Fornage M, Bressler J, Sotoodehnia N, Ong DA, Puddu F, Floyd JS, Ballantyne CM, Psaty BM, Raffield LM, Natarajan P, Conneely KN, Weinstock JS, Carson AP, Lange LA, Ferrier K, Heard-Costa NL, Murabito J, Bick AG, Levy D. Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation. Nat Commun. 2025 May 20; 16(1):4678.
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Hosseini M, Voisin V, Chegini A, Varesi A, Cathelin S, Ayyathan DM, Liu ACH, Yang Y, Wang V, Maher A, Grignano E, Reisz JA, D'Alessandro A, Young K, Wu Y, Fiumara M, Ferrari S, Naldini L, Gaiti F, Pai S, Egan G, Schimmer AD, Bader GD, Dick JE, Xie SZ, Trowbridge JJ, Chan SM. Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs. Nature. 2025 Jun; 642(8067):421-430.
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Young KA, Hosseini M, Mistry JJ, Morganti C, Mills TS, Cai X, James BT, Nye GJ, Fournier NR, Voisin V, Chegini A, Schimmer AD, Bader GD, Egan G, Mansour MR, Challen GA, Pietras EM, Fisher-Wellman KH, Ito K, Chan SM, Trowbridge JJ. Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis. Nat Commun. 2025 Apr 16; 16(1):3306.
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Nesbitt NM, Araldi GL, Pennacchia L, Marchenko N, Assar Z, Muzzarelli KM, Thekke Veedu RR, Medel-Lacruz B, Lee E, Eisenmesser EZ, Kreitler DF, Bahou WF. Small molecule BLVRB redox inhibitor promotes megakaryocytopoiesis and stress thrombopoiesis in vivo. Nat Commun. 2025 Apr 11; 16(1):3480.
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Darmusey L, Bagley AJ, Nguyen TT, Carlson HL, Blaylock H, Shrestha SB, Pang A, Tauchmann S, Taylor SC, Foley AC, Niño KE, Pietras EM, Braun TP, Maxson JE. Dual ASXL1 and CSF3R mutations drive myeloid-biased stem cell expansion and enhance neutrophil differentiation. Blood Adv. 2025 Apr 08; 9(7):1593-1607.
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Molteni R, Fiumara M, Campochiaro C, Alfieri R, Pacini G, Licari E, Tomelleri A, Diral E, Varesi A, Weber A, Quaranta P, Albano L, Gaddoni C, Basso-Ricci L, Stefanoni D, Alessandrini L, Degl'Innocenti S, Sanvito F, Bergonzi GM, Annoni A, Panigada M, Cantoni E, Canarutto D, Xie SZ, D'Alessandro A, Di Micco R, Aiuti A, Ciceri F, De Luca G, Dagna L, Matucci-Cerinic M, Merelli I, Cenci S, Scala S, Cavalli G, Naldini L, Ferrari S. Mechanisms of hematopoietic clonal dominance in VEXAS syndrome. Nat Med. 2025 Jun; 31(6):1911-1924.
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Feist WN, Luna SE, Ben-Efraim K, Filsinger Interrante MV, Amorin A, Johnston NM, Bruun TUJ, Utz A, Ghanim HY, Lesch BJ, McLaughlin TM, Dudek AM, Porteus MH. Multilayered HIV-1 resistance in HSPCs through CCR5 Knockout and B cell secretion of HIV-inhibiting antibodies. Nat Commun. 2025 Apr 01; 16(1):3103.
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