Centrosome
"Centrosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The cell center, consisting of a pair of CENTRIOLES surrounded by a cloud of amorphous material called the pericentriolar region. During interphase, the centrosome nucleates microtubule outgrowth. The centrosome duplicates and, during mitosis, separates to form the two poles of the mitotic spindle (MITOTIC SPINDLE APPARATUS).
Descriptor ID |
D018385
|
MeSH Number(s) |
A11.284.430.214.190.750.585.160 A11.284.430.214.190.750.820.500.500
|
Concept/Terms |
Pericentriolar Region- Pericentriolar Region
- Pericentriolar Regions
- Region, Pericentriolar
- Regions, Pericentriolar
|
Below are MeSH descriptors whose meaning is more general than "Centrosome".
Below are MeSH descriptors whose meaning is more specific than "Centrosome".
This graph shows the total number of publications written about "Centrosome" by people in this website by year, and whether "Centrosome" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
---|
1995 | 1 | 0 | 1 | 1996 | 1 | 0 | 1 | 1998 | 2 | 1 | 3 | 2002 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 | 2004 | 0 | 3 | 3 | 2005 | 0 | 1 | 1 | 2006 | 1 | 0 | 1 | 2007 | 1 | 3 | 4 | 2008 | 2 | 1 | 3 | 2009 | 0 | 2 | 2 | 2010 | 1 | 0 | 1 | 2011 | 2 | 0 | 2 | 2012 | 0 | 2 | 2 | 2013 | 0 | 1 | 1 | 2014 | 1 | 1 | 2 | 2015 | 0 | 1 | 1 | 2016 | 0 | 4 | 4 | 2018 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 | 2020 | 1 | 1 | 2 | 2021 | 0 | 3 | 3 | 2022 | 0 | 1 | 1 | 2023 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Centrosome" by people in Profiles.
-
Chun YW, Miyamoto M, Williams CH, Neitzel LR, Silver-Isenstadt M, Cadar AG, Fuller DT, Fong DC, Liu H, Lease R, Kim S, Katagiri M, Durbin MD, Wang KC, Feaster TK, Sheng CC, Neely MD, Sreenivasan U, Cortes-Gutierrez M, Finn AV, Schot R, Mancini GMS, Ament SA, Ess KC, Bowman AB, Han Z, Bichell DP, Su YR, Hong CC. Impaired Reorganization of Centrosome Structure Underlies Human Infantile Dilated Cardiomyopathy. Circulation. 2023 04 25; 147(17):1291-1303.
-
Jewett CE, McCurdy BL, O'Toole ET, Stemm-Wolf AJ, Given KS, Lin CH, Olsen V, Martin W, Reinholdt L, Espinosa JM, Sullivan KD, Macklin WB, Prekeris R, Pearson CG. Trisomy 21 induces pericentrosomal crowding delaying primary ciliogenesis and mouse cerebellar development. Elife. 2023 01 19; 12.
-
McCurdy BL, Jewett CE, Stemm-Wolf AJ, Duc HN, Joshi M, Espinosa JM, Prekeris R, Pearson CG. Trisomy 21 increases microtubules and disrupts centriolar satellite localization. Mol Biol Cell. 2022 07 01; 33(8).
-
Stemm-Wolf AJ, O'Toole ET, Sheridan RM, Morgan JT, Pearson CG. The SON RNA splicing factor is required for intracellular trafficking structures that promote centriole assembly and ciliogenesis. Mol Biol Cell. 2021 10 01; 32(20):ar4.
-
Jewett CE, Pearson CG. Cancer biology: Messages in extracellular vesicles depend on centrosome number. Curr Biol. 2021 04 12; 31(7):R337-R340.
-
Jewett CE, Soh AWJ, Lin CH, Lu Q, Lencer E, Westlake CJ, Pearson CG, Prekeris R. RAB19 Directs Cortical Remodeling and Membrane Growth for Primary Ciliogenesis. Dev Cell. 2021 02 08; 56(3):325-340.e8.
-
Sankaran DG, Stemm-Wolf AJ, McCurdy BL, Hariharan B, Pearson CG. A semi-automated machine learning-aided approach to quantitative analysis of centrosomes and microtubule organization. J Cell Sci. 2020 07 30; 133(14).
-
Turn RE, East MP, Prekeris R, Kahn RA. The ARF GAP ELMOD2 acts with different GTPases to regulate centrosomal microtubule nucleation and cytokinesis. Mol Biol Cell. 2020 08 15; 31(18):2070-2091.
-
Ganapathi Sankaran D, Stemm-Wolf AJ, Pearson CG. CEP135 isoform dysregulation promotes centrosome amplification in breast cancer cells. Mol Biol Cell. 2019 05 01; 30(10):1230-1244.
-
Galati DF, Sullivan KD, Pham AT, Espinosa JM, Pearson CG. Trisomy 21 Represses Cilia Formation and Function. Dev Cell. 2018 09 10; 46(5):641-650.e6.
|
People People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|