Alzheimer Disease
"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Descriptor ID |
D000544
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| MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.615.400.100
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| Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Alzheimer's Disease
- Dementia, Senile
- Senile Dementia
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Alzheimer-Type Dementia (ATD)
- Alzheimer Type Dementia (ATD)
- Dementia, Alzheimer-Type (ATD)
- Alzheimer Type Senile Dementia
- Primary Senile Degenerative Dementia
- Dementia, Primary Senile Degenerative
- Alzheimer Sclerosis
- Sclerosis, Alzheimer
- Alzheimer Syndrome
- Alzheimer Dementia
- Alzheimer Dementias
- Dementia, Alzheimer
- Dementias, Alzheimer
- Senile Dementia, Alzheimer Type
Familial Alzheimer Disease (FAD)- Familial Alzheimer Disease (FAD)
- Alzheimer Disease, Familial (FAD)
- Alzheimer Diseases, Familial (FAD)
- Familial Alzheimer Diseases (FAD)
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Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1995 | 1 | 0 | 1 | | 1996 | 3 | 0 | 3 | | 1997 | 3 | 1 | 4 | | 1998 | 8 | 0 | 8 | | 1999 | 2 | 1 | 3 | | 2000 | 6 | 2 | 8 | | 2001 | 4 | 2 | 6 | | 2002 | 4 | 1 | 5 | | 2003 | 8 | 0 | 8 | | 2004 | 5 | 1 | 6 | | 2005 | 12 | 4 | 16 | | 2006 | 7 | 4 | 11 | | 2007 | 18 | 4 | 22 | | 2008 | 12 | 2 | 14 | | 2009 | 9 | 2 | 11 | | 2010 | 17 | 3 | 20 | | 2011 | 11 | 3 | 14 | | 2012 | 14 | 6 | 20 | | 2013 | 7 | 2 | 9 | | 2014 | 9 | 2 | 11 | | 2015 | 16 | 3 | 19 | | 2016 | 14 | 5 | 19 | | 2017 | 11 | 3 | 14 | | 2018 | 8 | 3 | 11 | | 2019 | 12 | 5 | 17 | | 2020 | 20 | 4 | 24 | | 2021 | 20 | 6 | 26 | | 2022 | 39 | 0 | 39 | | 2023 | 31 | 1 | 32 | | 2024 | 16 | 5 | 21 | | 2025 | 16 | 5 | 21 |
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Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
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Walsemann KM, Jackson HM, Boardman JD, Herd P. APOE genotype and cognitive decline: educational context as a moderator of genetic risk. J Gerontol B Psychol Sci Soc Sci. 2025 Jul 25; 80(8).
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Goins RT, Shi Y, Corrada MM, Manson SM, O'Connell J, Jiang L. Longitudinal associations of depression and diabetes with Alzheimer's disease and related dementias risk among American Indian and Alaska Native peoples. J Gerontol A Biol Sci Med Sci. 2025 Jul 24; 80(8).
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Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, da Fonseca EL, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Ikeuchi T, Iqbal T, Pathak O, Valladares O, Reyes-Dumeyer D, Kuzma AB, Abner E, Adams LD, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Auerbach S, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Friedland RP, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Go RCP, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kikuchi M, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, Obisesan T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Petrovitch H, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sabbagh M, Sadovnick AD, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, George-Hyslop PS, Starks TD, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsolaki M, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Miyashita A, Byrd GS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj AC. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease. Genome Biol. 2025 Jul 17; 26(1):210.
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Carlisle TC, Bateman JR, Yang Y, Lachner C, Stockbridge MD, Flashman LA, Chemali Z, Alzbeidi N, Pressman PS, Osibajo AM, Bobrin BD, Martinez-Menendez CJ, Teixeira AL, Daffner KR. Antiamyloid Monoclonal Antibodies in Alzheimer's Disease, Part 2: Challenges in Dementia Care Delivery System Logistics. J Neuropsychiatry Clin Neurosci. 2025; 37(4):378-384.
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Wang H, Dombroski BA, Cheng PL, Tucci A, Si YQ, Farrell JJ, Tzeng JY, Leung YY, Malamon JS, Wang LS, Vardarajan BN, Farrer LA, Schellenberg GD, Lee WP. Structural variation detection and association analysis of whole-genome-sequence data from 16,543 Alzheimer's disease sequencing project subjects. Alzheimers Dement. 2025 Jun; 21(6):e70277.
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Shoaibi A, Ostropolets A, Weaver J, Rao GA, Golozar A, Swerdel J, Huser V, Adam A, Alshammari T, Anikpezie N, Baumgartner WA, Brand M, Fan R, Kanter AS, Kern D, Melisa S, Minty E, Mo J, Oluwalade B, Schilling LM, Spence H, Stocking JC, Zhang L, Ryan P. Variation in Phenotype Definitions in Observational Clinical Research: A Review of Three Conditions. AMIA Annu Symp Proc. 2024; 2024:1021-1029.
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Hebert LE, Kulbacki-Fabisiak C, Muller C, Boyd A, O'Leary M, Poole E, Ramos M, Barker D, Sinclair K, Manson SM, Buchwald D. Addressing the knowledge and recruitment gap in Alzheimer's disease and precision medicine research among Native people: an innovative randomized controlled trial. Ethn Health. 2025 May; 30(4):471-490.
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Wyman-Chick KA, Ferman TJ, Armstrong MJ, Chrenka EAB, Chiu SY, Patel B, Barrett MJ, Bayram E. Sex differences in prodromal dementia with Lewy bodies using the National Alzheimer's Coordinating Center data. Alzheimers Dement. 2025 May; 21(5):e70275.
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Bettcher BM, de Oliveira FF, Willette AA, Michalowska MM, Machado LS, Rajbanshi B, Borelli WV, Tansey MG, Rocha A, Suryadevara V, Hu WT. Analysis and interpretation of inflammatory fluid markers in Alzheimer's disease: a roadmap for standardization. J Neuroinflammation. 2025 Apr 15; 22(1):105.
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Lietzke EE, Saeb D, Aldrich EC, Bruce KD, Sprenger KG. Synergistic reduction in interfacial flexibility of TREM2R47H and ApoE4 may underlie AD pathology. Alzheimers Dement. 2025 Apr; 21(4):e70120.
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