 Alzheimer Disease
"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Descriptor ID |
D000544
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| MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.615.400.100
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| Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Alzheimer's Disease
- Dementia, Senile
- Senile Dementia
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Alzheimer-Type Dementia (ATD)
- Alzheimer Type Dementia (ATD)
- Dementia, Alzheimer-Type (ATD)
- Alzheimer Type Senile Dementia
- Primary Senile Degenerative Dementia
- Dementia, Primary Senile Degenerative
- Alzheimer Sclerosis
- Sclerosis, Alzheimer
- Alzheimer Syndrome
- Alzheimer Dementia
- Alzheimer Dementias
- Dementia, Alzheimer
- Dementias, Alzheimer
- Senile Dementia, Alzheimer Type
Familial Alzheimer Disease (FAD)- Familial Alzheimer Disease (FAD)
- Alzheimer Disease, Familial (FAD)
- Alzheimer Diseases, Familial (FAD)
- Familial Alzheimer Diseases (FAD)
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Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 | | 1995 | 1 | 0 | 1 | | 1996 | 2 | 0 | 2 | | 1997 | 3 | 0 | 3 | | 1998 | 7 | 0 | 7 | | 1999 | 3 | 1 | 4 | | 2000 | 5 | 2 | 7 | | 2001 | 4 | 1 | 5 | | 2002 | 3 | 1 | 4 | | 2003 | 8 | 0 | 8 | | 2004 | 5 | 1 | 6 | | 2005 | 13 | 4 | 17 | | 2006 | 7 | 4 | 11 | | 2007 | 16 | 4 | 20 | | 2008 | 12 | 2 | 14 | | 2009 | 9 | 2 | 11 | | 2010 | 15 | 3 | 18 | | 2011 | 10 | 3 | 13 | | 2012 | 12 | 6 | 18 | | 2013 | 5 | 2 | 7 | | 2014 | 10 | 1 | 11 | | 2015 | 13 | 3 | 16 | | 2016 | 13 | 5 | 18 | | 2017 | 9 | 5 | 14 | | 2018 | 5 | 4 | 9 | | 2019 | 11 | 5 | 16 | | 2020 | 18 | 4 | 22 | | 2021 | 18 | 5 | 23 | | 2022 | 29 | 0 | 29 | | 2023 | 23 | 1 | 24 | | 2024 | 4 | 0 | 4 |
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Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
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Chapleau M, La Joie R, Yong K, Agosta F, Allen IE, Apostolova L, Best J, Boon BDC, Crutch S, Filippi M, Fumagalli GG, Galimberti D, Graff-Radford J, Grinberg LT, Irwin DJ, Josephs KA, Mendez MF, Mendez PC, Migliaccio R, Miller ZA, Montembeault M, Murray ME, Nemes S, Pelak V, Perani D, Phillips J, Pijnenburg Y, Rogalski E, Schott JM, Seeley W, Sullivan AC, Spina S, Tanner J, Walker J, Whitwell JL, Wolk DA, Ossenkoppele R, Rabinovici GD. Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis. Lancet Neurol. 2024 02; 23(2):168-177.
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Aldecoa I, Barroeta I, Carroll SL, Fortea J, Gilmore A, Ginsberg SD, Guzman SJ, Hamlett ED, Head E, Perez SE, Potter H, Molina-Porcel L, Raha-Chowdhury R, Wisniewski T, Yong WH, Zaman S, Ghosh S, Mufson EJ, Granholm AC. Down Syndrome Biobank Consortium: A perspective. Alzheimers Dement. 2024 03; 20(3):2262-2272.
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Pelak VS, Krishnan V, Serva S, Pressman P, Mahmood A, Noteboom L, Bettcher BM, Sillau SH, Callen AL, Thaker AA. Lobar Microbleeds in the Posterior Cortical Atrophy Syndrome: A Comparison to Typical Alzheimer's Disease. Curr Neurol Neurosci Rep. 2024 02; 24(2):27-33.
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Cleland NRW, Potter GJ, Buck C, Quang D, Oldham D, Neal M, Saviola A, Niemeyer CS, Dobrinskikh E, Bruce KD. Altered metabolism and DAM-signatures in female brains and microglia with aging. Brain Res. 2024 Apr 15; 1829:148772.
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Philippou E, Hirsch MA, Heyn PC, van Wegen EEH, Darwish H. Vitamin D and Brain Health in Alzheimer and Parkinson Disease. Arch Phys Med Rehabil. 2024 04; 105(4):809-812.
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Foley KE, Winder Z, Sudduth TL, Martin BJ, Nelson PT, Jicha GA, Harp JP, Weekman EM, Wilcock DM. Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK-ADRC cohort. Alzheimers Dement. 2024 02; 20(2):1374-1386.
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Huang Q, Ying J, Yu W, Dong Y, Xiong H, Zhang Y, Liu J, Wang X, Hua F. P2X7 Receptor: an Emerging Target in Alzheimer's Disease. Mol Neurobiol. 2024 May; 61(5):2866-2880.
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Sallaberry CA, Voss BJ, Stone WB, Estrada F, Bhatia A, Soto JD, Griffin CW, Vander Zanden CM. Curcumin Reduces Amyloid Beta Oligomer Interactions with Anionic Membranes. ACS Chem Neurosci. 2023 11 15; 14(22):4026-4038.
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Powell WC, Jing R, Walczak MA. Chemical Synthesis of Microtubule-Associated Protein Tau. J Am Chem Soc. 2023 10 04; 145(39):21514-21526.
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Lynch MT, Taub MA, Farfel JM, Yang J, Abadir P, De Jager PL, Grodstein F, Bennett DA, Mathias RA. Evaluating genomic signatures of aging in brain tissue as it relates to Alzheimer's disease. Sci Rep. 2023 09 07; 13(1):14747.
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