Alzheimer Disease
"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Descriptor ID |
D000544
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| MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.615.400.100
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| Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Alzheimer's Disease
- Dementia, Senile
- Senile Dementia
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Alzheimer-Type Dementia (ATD)
- Alzheimer Type Dementia (ATD)
- Dementia, Alzheimer-Type (ATD)
- Alzheimer Type Senile Dementia
- Primary Senile Degenerative Dementia
- Dementia, Primary Senile Degenerative
- Alzheimer Sclerosis
- Sclerosis, Alzheimer
- Alzheimer Syndrome
- Alzheimer Dementia
- Alzheimer Dementias
- Dementia, Alzheimer
- Dementias, Alzheimer
- Senile Dementia, Alzheimer Type
Familial Alzheimer Disease (FAD)- Familial Alzheimer Disease (FAD)
- Alzheimer Disease, Familial (FAD)
- Alzheimer Diseases, Familial (FAD)
- Familial Alzheimer Diseases (FAD)
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Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 0 | 3 | | 1997 | 4 | 1 | 5 | | 1998 | 8 | 0 | 8 | | 1999 | 2 | 1 | 3 | | 2000 | 6 | 2 | 8 | | 2001 | 4 | 2 | 6 | | 2002 | 4 | 1 | 5 | | 2003 | 8 | 0 | 8 | | 2004 | 5 | 1 | 6 | | 2005 | 12 | 4 | 16 | | 2006 | 7 | 4 | 11 | | 2007 | 19 | 4 | 23 | | 2008 | 12 | 2 | 14 | | 2009 | 10 | 2 | 12 | | 2010 | 18 | 3 | 21 | | 2011 | 11 | 3 | 14 | | 2012 | 14 | 7 | 21 | | 2013 | 7 | 3 | 10 | | 2014 | 10 | 2 | 12 | | 2015 | 17 | 3 | 20 | | 2016 | 15 | 5 | 20 | | 2017 | 13 | 3 | 16 | | 2018 | 7 | 3 | 10 | | 2019 | 12 | 5 | 17 | | 2020 | 19 | 4 | 23 | | 2021 | 21 | 7 | 28 | | 2022 | 39 | 0 | 39 | | 2023 | 32 | 1 | 33 | | 2024 | 14 | 5 | 19 | | 2025 | 23 | 6 | 29 | | 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
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Kantarci K, Kara F, Tosakulwong N, Fought AJ, Schwarz CG, Senjem ML, Kendall-Thomas J, Min P, Lowe VJ, Jack CR, Kapoor E, Fields JA, Bailey KR, James TT, Faubion L, Lobo RA, Manson JE, Pal L, Hammers DB, Brinton EA, Malek-Ahmadi M, Cedars MI, Naftolin FN, Santoro N, Miller VM, Harman SM, Dowling NM, Gleason CE. Long-term amyloid PET and MRI outcomes in a menopausal hormone therapy trial. Alzheimers Dement. 2026 Feb; 22(2):e71067.
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Sillau SH, Coughlan C, Ahmed MM, Nair K, Araya P, Galbraith MD, Ritchie A, Ching-Jung Wang A, Elos MT, Bettcher BM, Espinosa JM, Chial HJ, Epperson N, Boyd TD, Potter H. Blood measure of neuronal death is exponentially higher with age, especially in females, and halted in Alzheimer's disease by GM-CSF treatment. Cell Rep Med. 2026 Jan 20; 7(1):102525.
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Tsai A, Gunn-Sandell LB, Wyman-Chick KA, Wang Y, Bayram E. Sex differences for symptoms prior to dementia onset in people with Lewy body pathology compared to pure Alzheimer's disease pathology. J Alzheimers Dis. 2026 Feb; 109(3):1188-1199.
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Choi DJ, Murali S, Kwon W, Woo J, Song EC, Ko Y, Sardar D, Lozzi B, Cheng YT, Williamson MR, Huang TW, Sanchez K, Jankowsky J, Deneen B. Astrocytic Sox9 overexpression in Alzheimer's disease mouse models promotes Aß plaque phagocytosis and preserves cognitive function. Nat Neurosci. 2026 Jan; 29(1):88-99.
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Gavett BE, Mungas D, Fletcher E, Robles I, Widaman K, Fan A, DeCarli C, Whitmer RA, Tomaszewski Farias S. Domain-specific changes in everyday cognition: Associations with diagnosis change and gray matter volume change. Neuropsychology. 2026 Jan; 40(1):3-16.
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Lanskey JH, Jafarian A, Hughes LE, Karadag M, Kocagoncu E, Rouse MA, Adams NE, Naessens M, Raymont V, Woolrich M, Singh KD, Henson RN, Rowe JB. Alzheimer's disease and memantine effects on NMDA-receptor blockade: non-invasive in vivo insights from magnetoencephalography. Mol Psychiatry. 2026 Mar; 31(3):1587-1596.
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Sprenger KG, Lietzke EE, Melchior JT, Bruce KD. Lipid and lipoprotein metabolism in microglia: Alzheimer's disease mechanisms and interventions. J Lipid Res. 2025 Oct; 66(10):100872.
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Cavalier AN, Smith ME, McWilliams GT, McEntee CM, Bettcher BM, Coughlan C, LaRocca TJ. Epigenetic dysregulation of transposable elements in cognitive impairment and Alzheimer's disease. Geroscience. 2025 Dec; 47(6):6731-6748.
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Walsemann KM, Jackson HM, Boardman JD, Herd P. APOE genotype and cognitive decline: educational context as a moderator of genetic risk. J Gerontol B Psychol Sci Soc Sci. 2025 Jul 25; 80(8).
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Goins RT, Shi Y, Corrada MM, Manson SM, O'Connell J, Jiang L. Longitudinal associations of depression and diabetes with Alzheimer's disease and related dementias risk among American Indian and Alaska Native peoples. J Gerontol A Biol Sci Med Sci. 2025 Jul 24; 80(8).
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