 Guanylate Cyclase
"Guanylate Cyclase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2.
| Descriptor ID |
D006162
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| MeSH Number(s) |
D08.811.520.650.600 D12.644.360.350 D12.776.476.350
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| Concept/Terms |
Guanylate Cyclase- Guanylate Cyclase
- Cyclase, Guanylate
- Guanyl Cyclase
- Cyclase, Guanyl
- Guanylyl Cyclase
- Cyclase, Guanylyl
- Inosinate Cyclase
- Cyclase, Inosinate
- Deoxyguanylate Cyclase
- Cyclase, Deoxyguanylate
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Below are MeSH descriptors whose meaning is more general than "Guanylate Cyclase".
Below are MeSH descriptors whose meaning is more specific than "Guanylate Cyclase".
This graph shows the total number of publications written about "Guanylate Cyclase" by people in this website by year, and whether "Guanylate Cyclase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 1 | 1 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 0 | 3 | 3 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanylate Cyclase" by people in Profiles.
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Giesinger RE, Stanford AH, Thomas B, Abman SH, McNamara PJ. Safety and Feasibility of Riociguat Therapy for the Treatment of Chronic Pulmonary Arterial Hypertension in Infancy. J Pediatr. 2023 04; 255:224-229.e1.
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Ma CA, Stinson JR, Zhang Y, Abbott JK, Weinreich MA, Hauk PJ, Reynolds PR, Lyons JJ, Nelson CG, Ruffo E, Dorjbal B, Glauzy S, Yamakawa N, Arjunaraja S, Voss K, Stoddard J, Niemela J, Zhang Y, Rosenzweig SD, McElwee JJ, DiMaggio T, Matthews HF, Jones N, Stone KD, Palma A, Oleastro M, Prieto E, Bernasconi AR, Dubra G, Danielian S, Zaiat J, Marti MA, Kim B, Cooper MA, Romberg N, Meffre E, Gelfand EW, Snow AL, Milner JD. Germline hypomorphic CARD11 mutations in severe atopic disease. Nat Genet. 2017 Aug; 49(8):1192-1201.
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Fussner LA, Krowka MJ. Current Approach to the Diagnosis and Management of Portopulmonary Hypertension. Curr Gastroenterol Rep. 2016 Jun; 18(6):29.
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Almhanna K, Kalebic T, Cruz C, Faris JE, Ryan DP, Jung J, Wyant T, Fasanmade AA, Messersmith W, Rodon J. Phase I Study of the Investigational Anti-Guanylyl Cyclase Antibody-Drug Conjugate TAK-264 (MLN0264) in Adult Patients with Advanced Gastrointestinal Malignancies. Clin Cancer Res. 2016 Oct 15; 22(20):5049-5057.
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Minarchick VC, Stapleton PA, Fix NR, Leonard SS, Sabolsky EM, Nurkiewicz TR. Intravenous and gastric cerium dioxide nanoparticle exposure disrupts microvascular smooth muscle signaling. Toxicol Sci. 2015 Mar; 144(1):77-89.
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Nozik-Grayck E, Woods C, Taylor JM, Benninger RK, Johnson RD, Villegas LR, Stenmark KR, Harrison DG, Majka SM, Irwin D, Farrow KN. Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2014 Dec 01; 307(11):L868-76.
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Brahmajothi MV, Tinch BT, Wempe MF, Endou H, Auten RL. Hyperoxia inhibits nitric oxide treatment effects in alveolar epithelial cells via effects on L-type amino acid transporter-1. Antioxid Redox Signal. 2014 Nov 01; 21(13):1823-36.
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Oliver JL, Kavoussi PK, Smith RP, Woodson RI, Corbett ST, Costabile RA, Palmer LA, Lysiak JJ. The role of regulatory proteins and S-nitrosylation of endothelial nitric oxide synthase in the human clitoris: implications for female sexual function. J Sex Med. 2014 Aug; 11(8):1927-35.
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Eytan O, Qiaoli L, Nousbeck J, van Steensel MA, Burger B, Hohl D, Ta?eb A, Prey S, Bachmann D, Avitan-Hersh E, Jin Chung H, Shemer A, Trau H, Bergman R, Fuchs-Telem D, Warshauer E, Israeli S, Itin PH, Sarig O, Uitto J, Sprecher E. Increased epidermal expression and absence of mutations in CARD14 in a series of patients with sporadic pityriasis rubra pilaris. Br J Dermatol. 2014 May; 170(5):1196-8.
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Purohit R, Fritz BG, The J, Issaian A, Weichsel A, David CL, Campbell E, Hausrath AC, Rassouli-Taylor L, Garcin ED, Gage MJ, Montfort WR. YC-1 binding to the ? subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the a subunit. Biochemistry. 2014 Jan 14; 53(1):101-14.
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