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Connection

Joaquin Espinosa to Animals

This is a "connection" page, showing publications Joaquin Espinosa has written about Animals.

 
Connection Strength
 
 
 
0.516
 
  1. Andrysik Z, Espinosa JM. Harnessing p53 for targeted cancer therapy: new advances and future directions. Transcription. 2025 02; 16(1):3-46.
    View in: PubMed
    Score: 0.046
  2. Donovan MG, Rachubinski AL, Smith KP, Araya P, Waugh KA, Enriquez-Estrada B, Britton EC, Lyford HR, Granrath RE, Schade KA, Kinning KT, Paul Eduthan N, Sullivan KD, Galbraith MD, Espinosa JM. Multimodal analysis of dysregulated heme metabolism, hypoxic signaling, and stress erythropoiesis in Down syndrome. Cell Rep. 2024 08 27; 43(8):114599.
    View in: PubMed
    Score: 0.044
  3. Waugh KA, Minter R, Baxter J, Chi C, Galbraith MD, Tuttle KD, Eduthan NP, Kinning KT, Andrysik Z, Araya P, Dougherty H, Dunn LN, Ludwig M, Schade KA, Tracy D, Smith KP, Granrath RE, Busquet N, Khanal S, Anderson RD, Cox LL, Estrada BE, Rachubinski AL, Lyford HR, Britton EC, Fantauzzo KA, Orlicky DJ, Matsuda JL, Song K, Cox TC, Sullivan KD, Espinosa JM. Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model. Nat Genet. 2023 06; 55(6):1034-1047.
    View in: PubMed
    Score: 0.041
  4. Tatavosian R, Donovan MG, Galbraith MD, Duc HN, Szwarc MM, Joshi MU, Frieman A, Bilousova G, Cao Y, Smith KP, Song K, Rachubinski AL, Andrysik Z, Espinosa JM. Cell differentiation modifies the p53 transcriptional program through a combination of gene silencing and constitutive transactivation. Cell Death Differ. 2023 04; 30(4):952-965.
    View in: PubMed
    Score: 0.040
  5. Andrysik Z, Sullivan KD, Kieft JS, Espinosa JM. PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response. Nat Commun. 2022 12 01; 13(1):7400.
    View in: PubMed
    Score: 0.039
  6. Galbraith MD, Andrysik Z, Sullivan KD, Espinosa JM. Global Analyses to Identify Direct Transcriptional Targets of p53. Methods Mol Biol. 2021; 2267:19-56.
    View in: PubMed
    Score: 0.034
  7. Powers RK, Culp-Hill R, Ludwig MP, Smith KP, Waugh KA, Minter R, Tuttle KD, Lewis HC, Rachubinski AL, Granrath RE, Carmona-Iragui M, Wilkerson RB, Kahn DE, Joshi M, Lleó A, Blesa R, Fortea J, D'Alessandro A, Costello JC, Sullivan KD, Espinosa JM. Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors. Nat Commun. 2019 10 18; 10(1):4766.
    View in: PubMed
    Score: 0.032
  8. Espinosa JM. Transcriptional CDKs in the spotlight. Transcription. 2019 04; 10(2):45-46.
    View in: PubMed
    Score: 0.030
  9. Sullivan KD, Galbraith MD, Andrysik Z, Espinosa JM. Mechanisms of transcriptional regulation by p53. Cell Death Differ. 2018 01; 25(1):133-143.
    View in: PubMed
    Score: 0.028
  10. Freeman JA, Espinosa JM. The impact of post-transcriptional regulation in the p53 network. Brief Funct Genomics. 2013 Jan; 12(1):46-57.
    View in: PubMed
    Score: 0.020
  11. Espinosa JM. Mechanisms of regulatory diversity within the p53 transcriptional network. Oncogene. 2008 Jul 03; 27(29):4013-23.
    View in: PubMed
    Score: 0.014
  12. Posey JN, Jordan M, Olsen-Dufour A, Nguyen TN, Farrell C, Lewis CV, Archambault JL, Sul C, Colon-Hidalgo D, Nozik ES, Espinosa JM, Sullivan KD, Delaney C. Interferon receptor gene dosage differentially regulates hypoxia-induced platelet activation and pulmonary hypertension in down syndrome. Front Immunol. 2026; 17:1832057.
    View in: PubMed
    Score: 0.012
  13. Lubkin A, Lujan RA, Pontejo SM, Oikonomou V, Fellows AM, Dos Santos Dias L, Snarr BD, MacAlpine J, Sullivan KD, Espinosa JM, Hickman H, Lionakis MS. The Dp16 Down syndrome mouse model does not exhibit oral interferon-gammopathy or susceptibility to oral candidiasis. mBio. 2026 03 11; 17(3):e0387325.
    View in: PubMed
    Score: 0.012
  14. Dunn LN, Niemeyer BF, Eduthan NP, Schade KA, Waugh KA, Brown C, Rachubinski AL, Timkovich AE, Orlicky DJ, Galbraith MD, Espinosa JM, Sullivan KD. Altered hepatic metabolism in Down syndrome. Cell Rep. 2026 Jan 27; 45(1):116835.
    View in: PubMed
    Score: 0.012
  15. Sillau SH, Coughlan C, Ahmed MM, Nair K, Araya P, Galbraith MD, Ritchie A, Ching-Jung Wang A, Elos MT, Bettcher BM, Espinosa JM, Chial HJ, Epperson N, Boyd TD, Potter H. Blood measure of neuronal death is exponentially higher with age, especially in females, and halted in Alzheimer's disease by GM-CSF treatment. Cell Rep Med. 2026 Jan 20; 7(1):102525.
    View in: PubMed
    Score: 0.012
  16. Reeser RS, VeDepo MC, Hewawasam RS, Waugh KA, Schade KA, Abdel-Hafiz M, Peña B, Mestroni L, Sbaizero O, Espinosa JM, Magin CM, Jacot JG. Aberrant tissue mechanics and mechanotransduction during heart development in down syndrome. J Biomech. 2026 Jan; 195:113103.
    View in: PubMed
    Score: 0.012
  17. Espinosa JM, Emerson BM. Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment. Mol Cell. 2001 Jul; 8(1):57-69.
    View in: PubMed
    Score: 0.009
  18. Tuttle KD, Waugh KA, Araya P, Minter R, Orlicky DJ, Ludwig M, Andrysik Z, Burchill MA, Tamburini BAJ, Sempeck C, Smith K, Granrath R, Tracy D, Baxter J, Espinosa JM, Sullivan KD. JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome. Cell Rep. 2020 11 17; 33(7):108407.
    View in: PubMed
    Score: 0.008
  19. Steinparzer I, Sedlyarov V, Rubin JD, Eislmayr K, Galbraith MD, Levandowski CB, Vcelkova T, Sneezum L, Wascher F, Amman F, Kleinova R, Bender H, Andrysik Z, Espinosa JM, Superti-Furga G, Dowell RD, Taatjes DJ, Kovarik P. Transcriptional Responses to IFN-? Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions. Mol Cell. 2019 11 07; 76(3):485-499.e8.
    View in: PubMed
    Score: 0.008
  20. Espinosa J, Martinetto H, Portal D, D'Angelo M, Torres HN, Flawiá MM. Factors from Trypanosoma cruzi interacting with AP-1 sequences. J Eukaryot Microbiol. 1999 Sep-Oct; 46(5):516-21.
    View in: PubMed
    Score: 0.008
  21. Oliphant MUJ, Vincent MY, Galbraith MD, Pandey A, Zaberezhnyy V, Rudra P, Johnson KR, Costello JC, Ghosh D, DeGregori J, Espinosa JM, Ford HL. SIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell Program. Cancer Res. 2019 02 15; 79(4):720-734.
    View in: PubMed
    Score: 0.007
  22. Riera FL, Roldán JE, Espinosa JM, Fernandez JE, Ortiz I, Hinrichs K. Application of embryo biopsy and sex determination via polymerase chain reaction in a commercial equine embryo transfer program in Argentina. Reprod Fertil Dev. 2019 Jan; 31(12):1917-1925.
    View in: PubMed
    Score: 0.007
  23. Fleenor CJ, Arends T, Lei H, Åhsberg J, Okuyama K, Kuruvilla J, Cristobal S, Rabe JL, Pandey A, Danhorn T, Straign D, Espinosa JM, Warming S, Pietras EM, Sigvardsson M, Hagman JR. Zinc Finger Protein 521 Regulates Early Hematopoiesis through Cell-Extrinsic Mechanisms in the Bone Marrow Microenvironment. Mol Cell Biol. 2018 09 01; 38(17).
    View in: PubMed
    Score: 0.007
  24. Galati DF, Sullivan KD, Pham AT, Espinosa JM, Pearson CG. Trisomy 21 Represses Cilia Formation and Function. Dev Cell. 2018 09 10; 46(5):641-650.e6.
    View in: PubMed
    Score: 0.007
  25. Liang K, Volk AG, Haug JS, Marshall SA, Woodfin AR, Bartom ET, Gilmore JM, Florens L, Washburn MP, Sullivan KD, Espinosa JM, Cannova J, Zhang J, Smith ER, Crispino JD, Shilatifard A. Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia. Cell. 2017 Jan 12; 168(1-2):59-72.e13.
    View in: PubMed
    Score: 0.006
  26. Tentler JJ, Ionkina AA, Tan AC, Newton TP, Pitts TM, Glogowska MJ, Kabos P, Sartorius CA, Sullivan KD, Espinosa JM, Eckhardt SG, Diamond JR. p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer. Mol Cancer Ther. 2015 May; 14(5):1117-29.
    View in: PubMed
    Score: 0.006
  27. Galbraith MD, Saxton J, Li L, Shelton SJ, Zhang H, Espinosa JM, Shaw PE. ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1. Nucleic Acids Res. 2013 Dec; 41(22):10241-53.
    View in: PubMed
    Score: 0.005
  28. Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R. The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha. Cell. 2010 Jan 22; 140(2):280-93.
    View in: PubMed
    Score: 0.004
  29. Diaz Añel AM, Rossi MS, Espinosa JM, Güida C, Freitas FA, Kornblihtt AR, Zingales B, Flawia MM, Torres HN. MRNA encoding a putative RNA helicase of the DEAD-box gene family is up-regulated in trypomastigotes of Trypanosoma cruzi. J Eukaryot Microbiol. 2000 Nov-Dec; 47(6):555-60.
    View in: PubMed
    Score: 0.002
  30. Pereira C, Paveto C, Espinosa J, Alonso G, Flawiá MM, Torres HN. Control of Trypanosoma cruzi epimastigote motility through the nitric oxide pathway. J Eukaryot Microbiol. 1997 Mar-Apr; 44(2):155-6.
    View in: PubMed
    Score: 0.002
  31. Paveto C, Pereira C, Espinosa J, Montagna AE, Farber M, Esteva M, Flawiá MM, Torres HN. The nitric oxide transduction pathway in Trypanosoma cruzi. J Biol Chem. 1995 Jul 14; 270(28):16576-9.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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