 Toll-Like Receptors
"Toll-Like Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
| Descriptor ID |
D051193
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| MeSH Number(s) |
D12.776.543.750.705.910.500
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| Concept/Terms |
Toll-Like Receptors- Toll-Like Receptors
- Toll Like Receptors
- Toll-Like Receptor
- Receptor, Toll-Like
- Toll Like Receptor
- Receptors, Toll-Like
- Receptors, Toll Like
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Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptors".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptors".
This graph shows the total number of publications written about "Toll-Like Receptors" by people in this website by year, and whether "Toll-Like Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2000 | 0 | 3 | 3 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 8 | 8 | | 2003 | 0 | 4 | 4 | | 2004 | 0 | 13 | 13 | | 2005 | 1 | 7 | 8 | | 2006 | 1 | 3 | 4 | | 2007 | 3 | 3 | 6 | | 2008 | 5 | 2 | 7 | | 2009 | 2 | 4 | 6 | | 2010 | 5 | 2 | 7 | | 2011 | 4 | 6 | 10 | | 2012 | 2 | 2 | 4 | | 2013 | 2 | 5 | 7 | | 2014 | 2 | 4 | 6 | | 2015 | 2 | 3 | 5 | | 2016 | 1 | 2 | 3 | | 2017 | 2 | 4 | 6 | | 2018 | 1 | 3 | 4 | | 2019 | 1 | 0 | 1 | | 2020 | 2 | 4 | 6 | | 2021 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Toll-Like Receptors" by people in Profiles.
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Glaser K, Kern D, Speer CP, Schlegel N, Schwab M, Thome UH, H?rtel C, Wright CJ. Imbalanced Inflammatory Responses in Preterm and Term Cord Blood Monocytes and Expansion of the CD14+CD16+ Subset upon Toll-like Receptor Stimulation. Int J Mol Sci. 2023 Mar 03; 24(5).
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Lennard Richard ML, Wirth JR, Khatiwada A, Chung D, Gilkeson GS, Cunningham MA. Conditional knockout of oestrogen receptor alpha in CD11c+ cells impacts female survival and inflammatory cytokine profile in murine lupus. Immunology. 2022 11; 167(3):354-367.
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Pardeshi NN, Ahmadi M, Sierzputowska I, Fogg M, Baker M, Carpenter JF. Subvisible Particles in Solutions of Remicade in Intravenous Saline Activate Immune System Pathways in In Vitro Human Cell Systems. J Pharm Sci. 2021 08; 110(8):2894-2903.
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Pezzanite LM, Chow L, Johnson V, Griffenhagen GM, Goodrich L, Dow S. Toll-like receptor activation of equine mesenchymal stromal cells to enhance antibacterial activity and immunomodulatory cytokine secretion. Vet Surg. 2021 May; 50(4):858-871.
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Okamato Y, Ghosh T, Okamoto T, Schuyler RP, Seifert J, Charry LL, Visser A, Feser M, Fleischer C, Pedrick C, August J, Moss L, Bemis EA, Norris JM, Kuhn KA, Demoruelle MK, Deane KD, Ghosh D, Holers VM, Hsieh EWY. Subjects at-risk for future development of rheumatoid arthritis demonstrate a PAD4-and TLR-dependent enhanced histone H3 citrullination and proinflammatory cytokine production in CD14hi monocytes. J Autoimmun. 2021 02; 117:102581.
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Tuttle KD, Waugh KA, Araya P, Minter R, Orlicky DJ, Ludwig M, Andrysik Z, Burchill MA, Tamburini BAJ, Sempeck C, Smith K, Granrath R, Tracy D, Baxter J, Espinosa JM, Sullivan KD. JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome. Cell Rep. 2020 11 17; 33(7):108407.
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Marinaik CB, Kingstad-Bakke B, Lee W, Hatta M, Sonsalla M, Larsen A, Neldner B, Gasper DJ, Kedl RM, Kawaoka Y, Suresh M. Programming Multifaceted Pulmonary T Cell Immunity by Combination Adjuvants. Cell Rep Med. 2020 09 22; 1(6):100095.
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Agazio A, Cimons J, Shotts KM, Guo K, Santiago ML, Pelanda R, Torres RM. Histone H2A-Reactive B Cells Are Functionally Anergic in Healthy Mice With Potential to Provide Humoral Protection Against HIV-1. Front Immunol. 2020; 11:1565.
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Soman SP, Singh SK, Kumari P, Choudhury S, Singh A, Kanwal S, Khushboo R, Garg SK. Quantification of immuno-regulatory cytokine and toll-like receptors gene expression in dogs with generalized demodicosis. Vet Parasitol. 2020 Apr; 280:109063.
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Hinks TSC, van Wilgenburg B, Wang H, Loh L, Koutsakos M, Kedzierska K, Corbett AJ, Chen Z. Study of MAIT Cell Activation in Viral Infections In Vivo. Methods Mol Biol. 2020; 2098:261-281.
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