Polymorphism, Single Nucleotide
"Polymorphism, Single Nucleotide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.
| Descriptor ID |
D020641
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| MeSH Number(s) |
G05.365.795.598
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| Concept/Terms |
Polymorphism, Single Nucleotide- Polymorphism, Single Nucleotide
- Nucleotide Polymorphism, Single
- Nucleotide Polymorphisms, Single
- Polymorphisms, Single Nucleotide
- Single Nucleotide Polymorphisms
- SNPs
- Single Nucleotide Polymorphism
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Below are MeSH descriptors whose meaning is more general than "Polymorphism, Single Nucleotide".
Below are MeSH descriptors whose meaning is more specific than "Polymorphism, Single Nucleotide".
This graph shows the total number of publications written about "Polymorphism, Single Nucleotide" by people in this website by year, and whether "Polymorphism, Single Nucleotide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2001 | 6 | 6 | 12 | | 2002 | 2 | 4 | 6 | | 2003 | 2 | 3 | 5 | | 2004 | 9 | 5 | 14 | | 2005 | 10 | 15 | 25 | | 2006 | 17 | 19 | 36 | | 2007 | 17 | 28 | 45 | | 2008 | 39 | 33 | 72 | | 2009 | 30 | 44 | 74 | | 2010 | 33 | 57 | 90 | | 2011 | 42 | 46 | 88 | | 2012 | 27 | 72 | 99 | | 2013 | 38 | 64 | 102 | | 2014 | 40 | 70 | 110 | | 2015 | 26 | 62 | 88 | | 2016 | 28 | 64 | 92 | | 2017 | 24 | 76 | 100 | | 2018 | 29 | 52 | 81 | | 2019 | 17 | 64 | 81 | | 2020 | 18 | 42 | 60 | | 2021 | 16 | 50 | 66 | | 2022 | 9 | 41 | 50 | | 2023 | 5 | 24 | 29 | | 2024 | 15 | 35 | 50 | | 2025 | 3 | 44 | 47 |
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Below are the most recent publications written about "Polymorphism, Single Nucleotide" by people in Profiles.
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Raghavan S, Litkowski E, Jensen A, Charest B, Wang Z, Hui Q, Chen HC, Rhee MK, Leong A, Meigs JB, Lange L, Lange E, Reaven P, Hung A, Zhou J, Sun YV, Phillips LS. Genome-Wide Association Study of Hypoglycemia in Adults With Diabetes in the Million Veteran Program. Diabetes. 2025 Dec 01; 74(12):2432-2443.
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Gonçalves SM, Leite L, de Vasconcelos P, Pereira I, Dewi IMW, Mercier T, Aerts R, Ligeiro D, Mendes F, Freitas F, Condeço J, Vieira J, Espada E, Lagrou K, Maertens JA, Gresnigt MS, Dinarello CA, Lacerda JF, Pinho Vaz C, Cunha C, Carvalho A, van de Veerdonk FL. A Functional Polymorphism in IL-36ß Modulates Macrophage Antifungal Effector Functions and Increases Susceptibility to Invasive Pulmonary Aspergillosis. J Infect Dis. 2025 Nov 14; 232(5):1208-1219.
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Romero Villela PN, Kelly KM, Balbona JV, Ehringer MA, Keller MC. Maternal Smoking During Pregnancy Interacts With Genetic Factors to Increase Risk for Low Birth Weight but Not Harmful Offspring Smoking Behaviors in Europeans. Nicotine Tob Res. 2025 Sep 23; 27(10):1795-1804.
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van der Laan CM, Ip HF, Schipper M, Hottenga JJ, St Pourcain B, Zayats T, Pool R, Krapohl EML, Brikell I, Soler Artigas M, Cabana-Domínguez J, Llonga N, Nolte IM, Bolhuis K, Palviainen T, Zafarmand H, Gordon S, Aliev F, Burt SA, Wang CA, Saunders G, Karhunen V, Adkins DE, Border R, Peterson RE, Prinz JA, Thiering E, Vilor-Tejedor N, Ahluwalia TS, Allegrini A, Rimfeld K, Chen Q, Lu Y, Martin J, Bosch R, Ramos-Quiroga JA, Neumann A, Ensink J, Grasby KL, Morosoli JJ, Tong X, Marrington S, Scott JG, Shabalin AA, Corley R, Evans LM, Sugden K, Alemany S, Sass L, Vinding R, Ehli EA, Hagenbeek FA, Derks EM, Larsson H, Snieder H, Cecil C, Whipp AM, Korhonen T, Vuoksimaa E, Rose RJ, Uitterlinden AG, Haavik J, Harris JR, Helgeland Ø, Johansson S, Knudsen GPS, Njolstad PR, Lu Q, Rodriguez A, Henders AK, Mamun A, Najman JM, Brown S, Hopfer C, Krauter K, Reynolds CA, Smolen A, Stallings M, Wadsworth S, Wall TL, Eaves L, Silberg JL, Miller A, Havdahl A, Llop S, Lopez-Espinosa MJ, Bønnelykke K, Sunyer J, Arseneault L, Standl M, Heinrich J, Boden J, Pearson J, Horwood J, Kennedy M, Poulton R, Maes HH, Hewitt J, Copeland WE, Middeldorp CM, Williams GM, Wray N, Järvelin MR, McGue M, Iacono W, Caspi A, Moffitt TE, Whitehouse AJO, Pennell CE, Klump KL, Jiang C, Dick DM, Reichborn-Kjennerud T, Martin NG, Medland SE, Vrijkotte T, Kaprio J, Tiemeier H, Davey Smith G, Hartman CA, Oldehinkel AJ, Casas M, Ribasés M, Lichtenstein P, Lundström S, Plomin R, Bartels M, Nivard MG, Boomsma DI. Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes. Nat Genet. 2025 Oct; 57(10):2427-2435.
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Krishnan M, Anwar MY, Justice AE, Chittoor G, Chen HH, Roshani R, Scartozzi A, Dickerson RR, Smit RAJ, Preuss MH, Chami N, Hadad BS, Parra EJ, Cruz M, Hui Q, Wilson PWF, Sun YV, Zhang X, Linchangco GV, Kardia SLR, Faul JD, Weir DR, Bielak LF, Highland HM, Young KL, Qi B, Wang Y, Fornage M, Haiman C, Cheng I, Peters U, Kooperberg C, Buyske S, McCormick JB, Fisher-Hoch SP, Lona-Durazo F, Peralta J, Gomez-Zamudio J, Rich SS, Ferrier KR, Lange EM, Gignoux CR, Kenny EE, Wojcik GL, Cho K, Gaziano MJ, Djousse L, Liu S, Vaidya D, de Mutsert R, Josyula NS, Bauer CR, Zhao W, Walker RW, Smith JA, Lange LA, Meyer MC, Liu CT, Yanek LR, Lee M, Raffield LM, Loos RJF, Gordon-Larsen P, Below JE, North KE, Graff M. Genome-wide association study provides novel insight into the genetic architecture of severe obesity. PLoS Genet. 2025 Sep; 21(9):e1011842.
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Selvaraj MS, Li X, Li Z, Van Buren E, Haidermota S, Postupaka D, Hornsby W, Bis JC, Brody JA, Cade BE, Chung RH, Curran JE, Damrauer SM, de Las Fuentes L, de Vries PS, Duggirala R, Freedman BI, Graff M, Guo X, Hidalgo BA, Hou L, Irvin R, Judy R, Kalyani RR, Kelly TN, Konigsberg IR, Kral BG, Kwee LC, Levy D, Li C, Manichaikul AW, Martin LW, Montasser ME, Morrison AC, Naseri T, North KE, O'Connell JR, Palmer ND, Peyser PA, Reiner AP, Shah SH, Smit RAJ, Smith JA, Taylor KD, Tiwari H, Tsai MY, Viali S, Wang Z, Wang Y, Zhao W, Arnett DK, Blangero J, Boerwinkle E, Bowden DW, Carlson JC, Chen YI, Ellinor PT, Fornage M, He J, Heard-Costa N, Kaplan RC, Kardia SLR, Kooperberg C, Kraus WE, Lange LA, Loos RJF, Mitchell BD, Psaty BM, Rader DJ, Redline S, Rich SS, Yanek LR, Gibbs R, Gabriel S, Viaud-Martinez KA, Dutcher SK, Germer S, Kim R, Rotter JI, Lin X, Peloso GM, Natarajan P. Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals. Genome Biol. 2025 Sep 09; 26(1):273.
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Haller PM, Melloni GEM, Berg DD, Kamanu FK, Lai YP, Antman EM, Bhatt DL, Bonaca MP, Cannon CP, Giugliano RP, O'Donoghue ML, Scirica BM, Wiviott SD, Chasman D, Everett BM, Braunwald E, Morrow DA, Ridker PM, Ellinor PT, Sabatine MS, Ruff CT, Marston NA. A Polygenic Risk Score to Predict Incident Heart Failure Across the Spectrum of Cardiovascular Risk. J Am Coll Cardiol. 2025 Sep 23; 86(12):860-873.
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Johnson EC, Lai D, Balbona JV, Miller AP, Hatoum AS, Deak JD, Jennings M, Baranger DAA, Galimberti M, Sanichwankul K, Thorgeirsson T, Colbert SMC, Adhikari K, Docherty AR, Degenhardt L, Edwards T, Fox L, Giannelis A, Jeffries PW, Korhonen T, Morrison CL, Nunez YZ, Palviainen T, Su MH, Romero Villela PN, Wetherill L, Willoughby EA, Zellers SM, Bierut LJ, Buchwald J, Copeland WE, Corley RP, Friedman NP, Foroud TM, Gillespie NA, Gizer IR, Heath AC, Hickie IB, Kaprio J, Keller MC, Lee JJ, Lind P, Madden PA, Maes HHM, Martin NG, McGue M, Medland SE, Nelson EC, Pearson J, Porjesz B, Stallings MC, Vrieze S, Wilhelmson KC, Kranzler HR, Walters RK, Polimanti R, Malison R, Zhou H, Stefansson K, Sanchez-Roige S, Potenza M, Mutirangura A, Shotelersuk V, Kalayasiri R, Edenberg HJ, Gelernter J, Agrawal A. Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. Psychol Med. 2025 Aug 20; 55:e234.
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Zane LK, Yee LM, Chang TC, Sklar J, Yang G, Wen JD, Li P, Harrington R, Sims DJ, Harper K, Trent JM, LoBello JR, Szelinger S, Benson K, Zeng J, Poorman K, Xu D, Frampton GM, Pavlick DC, Miller VA, Tandon B, Swat W, Weiss L, Funari VA, Conroy JM, Prescott JL, Chandra PK, Ma C, Champion KJ, Baschkopf GX, Fesko YA, Freitas TAK, Tomlins SA, Hovelson DH, White K, Sorrells S, Tell R, Beaubier N, King D, Li L, Kelly K, Uvalic J, Meyers B, Kolhe R, Lindeman NI, Baltay M, Sholl LM, Lopategui J, Vail E, Zhang W, Telatar M, Afkhami M, Hsiao SJ, Mansukhani MM, Adams E, Jiang L, Aldape KD, Raffeld M, Xi L, Stehr H, Segal JP, Aisner DL, Davies KD, Brown NA, Livingston RJ, Konnick EQ, Song W, Solomon JP, Walther Z, McShane LM, Harris LN, Chen AP, Tsongalis GJ, Hamilton SR, Flaherty KT, O'Dwyer PJ, Conley BA, Patton DR, Iafrate AJ, Williams PM, Tricoli JV, Karlovich C. A Concordance Study among 26 NGS Laboratories Participating in the NCI Molecular Analysis for Therapy Choice Clinical Trial. Clin Cancer Res. 2025 Aug 14; 31(16):3512-3525.
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Arehart CH, Lin M, Gibson RA, Raghavan S, Gignoux CR, Stanislawski MA, Grotzinger AD, Evans LM. Modeling the genomic architecture of adiposity and anthropometrics across the lifespan. Nat Commun. 2025 Aug 13; 16(1):7494.
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