Polymorphism, Single Nucleotide
"Polymorphism, Single Nucleotide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.
| Descriptor ID |
D020641
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| MeSH Number(s) |
G05.365.795.598
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| Concept/Terms |
Polymorphism, Single Nucleotide- Polymorphism, Single Nucleotide
- Nucleotide Polymorphism, Single
- Nucleotide Polymorphisms, Single
- Polymorphisms, Single Nucleotide
- Single Nucleotide Polymorphisms
- SNPs
- Single Nucleotide Polymorphism
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Below are MeSH descriptors whose meaning is more general than "Polymorphism, Single Nucleotide".
Below are MeSH descriptors whose meaning is more specific than "Polymorphism, Single Nucleotide".
This graph shows the total number of publications written about "Polymorphism, Single Nucleotide" by people in this website by year, and whether "Polymorphism, Single Nucleotide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2001 | 6 | 6 | 12 | | 2002 | 2 | 4 | 6 | | 2003 | 2 | 3 | 5 | | 2004 | 9 | 5 | 14 | | 2005 | 10 | 15 | 25 | | 2006 | 17 | 19 | 36 | | 2007 | 18 | 28 | 46 | | 2008 | 38 | 32 | 70 | | 2009 | 31 | 42 | 73 | | 2010 | 30 | 57 | 87 | | 2011 | 41 | 44 | 85 | | 2012 | 25 | 68 | 93 | | 2013 | 38 | 62 | 100 | | 2014 | 39 | 67 | 106 | | 2015 | 24 | 59 | 83 | | 2016 | 26 | 63 | 89 | | 2017 | 23 | 78 | 101 | | 2018 | 26 | 50 | 76 | | 2019 | 17 | 61 | 78 | | 2020 | 18 | 40 | 58 | | 2021 | 16 | 51 | 67 | | 2022 | 9 | 41 | 50 | | 2023 | 5 | 24 | 29 | | 2024 | 15 | 35 | 50 | | 2025 | 4 | 50 | 54 | | 2026 | 2 | 4 | 6 |
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Below are the most recent publications written about "Polymorphism, Single Nucleotide" by people in Profiles.
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Aydemir O, Bailey JA, Agardh D, Lernmark Å, Noble JA, Andersson Svärd A, Blankenhorn EP, Parikh HM, Ziegler AG, Toppari J, Akolkar B, Hagopian WA, Rewers MJ, Mordes JP. Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B. Elife. 2026 Feb 02; 12.
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You L, Parikh HM, Triolo TM, Ferrat LA, Templeman EL, Oram RA, Gottlieb PA, Rich SS, Onengut-Gumuscu S, Steck AK, Krischer J, Redondo MJ. Genetic Predictors of Response to Oral Insulin for Type 1 Diabetes Prevention. Diabetes Care. 2026 Feb 01; 49(2):344-351.
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Shetty NS, Pampana A, Gaonkar M, Nayak A, Bal HS, Patel N, Vekariya N, Smith JG, Morrison AC, Yu B, Psaty BM, Boerwinkle E, Floyd JS, Rotter JI, Taylor KD, Lange LA, Irvin MR, Cushman M, Rich SS, Vasan RS, Wang TJ, Guo X, Li P, Arora G, Arora P. Genetic Architecture of N-Terminal Pro-B-Type Natriuretic Peptide in a Multiancestry Study Population. Circ Genom Precis Med. 2026 Feb; 19(1):e005130.
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Nicholas JC, Katz DH, Tahir UA, Debban CL, Aguet F, Blackwell T, Bowler RP, Broadaway KA, Chen J, Clish CB, Coresh J, Cornell E, Cruz DE, Deo R, Doyle MF, Durda P, Ekunwe L, Floyd JS, Gill D, Guo X, Hoogeveen RC, Johnson C, Lange LA, Li Y, Manning A, Meigs JB, Mi MY, Mychaleckyj JC, Olson NC, Pratte KA, Psaty BM, Reiner AP, Ruan P, Sevilla-Gonzalez M, Shah AM, Sun Q, Tracy RP, Wen J, Wood AC, Wilson JG, Young KL, Yu B, Rooney MR, Manichaikul A, Dubin R, Mohlke KL, Rich SS, Rotter JI, Ganz P, Gerszten RE, Taylor KD, Raffield LM. Cross-ancestry comparison of aptamer and antibody protein measures. Nat Commun. 2026 Jan 22; 17(1):1054.
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Steck AK, Parikh HM, Triolo TM, Ferrat L, You L, Gottlieb PA, Oram RA, Onengut-Gumuscu S, Krischer JP, Rich SS, Redondo MJ. Genetic Risk and Transition Through Preclinical Stages of Type 1 Diabetes. J Clin Endocrinol Metab. 2026 Jan 21; 111(2):e493-e499.
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Vollenbrock CE, Roshandel D, Lee KE, Klein BE, Mul D, van der Klauw MM, Tack CJ, Rewers M, Snell-Bergeon JK, Costacou T, Miller RG, Caramori ML, Mauer M, Aanstoot HJ, Wolffenbuttel BHR, Paterson AD. Association of genetic variation with age at diagnosis in type 1 diabetes. BMJ Open Diabetes Res Care. 2026 Jan 16; 14(1).
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Small AM, Yang TY, Itoh S, Thériault S, Dufresne L, Kurosawa R, Komuro I, Matsuda K, Vy HMT, Farber-Eger EH, Shaffer LL, Boulier KM, Corey KM, Ramaker ME, Laporte F, Schott JJ, Le Scouarnec S, Singh SA, Sonawane AR, Smith HA, Rafaels N, Ghouse J, Raja AA, Ostrowski SR, Sørensen E, Mikkelsen C, Pedersen OB, Erikstrup C, Ullum H, Sveinbjornsson G, Gudbjartsson DF, Abner E, Lee J, Ganna A, Nowak-Göttl U, Finer S, Schumacher J, Maj C, Al-Kassou B, Nickenig G, Trenkwalder T, Dreßen M, Krane M, Nöthen MM, Moksnes MR, Brumpton BM, Knight S, Knowlton KU, Nadauld L, Debiec R, Musameh MD, Braund PS, Nelson CP, Czuba T, Melander O, Selvaraj MS, Koyama S, Bhukar R, Ruan Y, Ljungberg J, Damrauer SM, Levin MG, Franke A, Berger K, Ruff CT, Melloni GEM, Kamanu FK, Ito K, Do R, Loos RJF, Schunkert H, Wells QS, Shah SH, Le Tourneau T, Messika-Zeitoun D, Gignoux C, Bundgaard H, Larsson SC, Michaëlsson K, Holm H, Helgadottir A, Esko T, van Heel DA, Mathieu P, Samani NJ, Smith JG, Söderberg S, Rader DJ, Marston NA, Sabatine MS, Pasaniuc B, Cho K, Wilson PWF, O'Donnell CJ, Stefansson K, Bossé Y, Aikawa E, Engert JC, Peloso GM, Natarajan P, Thanassoulis G. Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction. Nat Genet. 2026 Jan; 58(1):57-66.
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Raghavan S, Litkowski E, Jensen A, Charest B, Wang Z, Hui Q, Chen HC, Rhee MK, Leong A, Meigs JB, Lange L, Lange E, Reaven P, Hung A, Zhou J, Sun YV, Phillips LS. Genome-Wide Association Study of Hypoglycemia in Adults With Diabetes in the Million Veteran Program. Diabetes. 2025 Dec 01; 74(12):2432-2443.
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Thorpe HHA, Cupertino RB, Pakala SR, Fontanillas P, Jennings MV, Yang J, Meredith JJ, Greenwood T, Bianchi SB, Vilar-Ribó L, Niarchou M, Elson SL, Ideker T, Davis LK, MacKillop J, deWit H, Gustavson DE, Mallard TT, Palmer AA, Sanchez-Roige S. Genome-wide association study of delay discounting identifies 11 loci and reveals transdiagnostic associations across mental and physical health. Mol Psychiatry. 2026 Apr; 31(4):2081-2093.
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Gonçalves SM, Leite L, de Vasconcelos P, Pereira I, Dewi IMW, Mercier T, Aerts R, Ligeiro D, Mendes F, Freitas F, Condeço J, Vieira J, Espada E, Lagrou K, Maertens JA, Gresnigt MS, Dinarello CA, Lacerda JF, Pinho Vaz C, Cunha C, Carvalho A, van de Veerdonk FL. A Functional Polymorphism in IL-36ß Modulates Macrophage Antifungal Effector Functions and Increases Susceptibility to Invasive Pulmonary Aspergillosis. J Infect Dis. 2025 Nov 14; 232(5):1208-1219.
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