 Tumor Protein p73
"Tumor Protein p73" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homolog of p53 TUMOR SUPPRESSOR PROTEIN that encodes full-length trans-activating and N-terminally-truncated (DeltaN) isoforms. Detection of splice variants and isoforms in the nervous system (human TELENCEPHALON, CHOROID PLEXUS; CEREBROSPINAL FLUID), embryonic tissue, human BREAST CANCER; OVARIAN CANCER, suggest roles in cellular differentiation.
| Descriptor ID |
D000072160
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| MeSH Number(s) |
D12.776.260.885 D12.776.624.776.820 D12.776.660.912 D12.776.930.969
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| Concept/Terms |
Tumor Protein p73- Tumor Protein p73
- Protein p73, Tumor
- p73, Tumor Protein
- Protein p73
- p73, Protein
- p73 Protein
- Protein, p73
- Tumor Suppressor Protein p73
- Tap73 Protein, Human
- Human Tap73 Protein
- Protein, Human Tap73
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Below are MeSH descriptors whose meaning is more general than "Tumor Protein p73".
Below are MeSH descriptors whose meaning is more specific than "Tumor Protein p73".
This graph shows the total number of publications written about "Tumor Protein p73" by people in this website by year, and whether "Tumor Protein p73" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tumor Protein p73" by people in Profiles.
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Sinha N, Panda PK, Naik PP, Das DN, Mukhopadhyay S, Maiti TK, Shanmugam MK, Chinnathambi A, Zayed ME, Alharbi SA, Sethi G, Agarwal R, Bhutia SK. Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma. Mol Carcinog. 2017 Nov; 56(11):2400-2413.
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Tentler JJ, Ionkina AA, Tan AC, Newton TP, Pitts TM, Glogowska MJ, Kabos P, Sartorius CA, Sullivan KD, Espinosa JM, Eckhardt SG, Diamond JR. p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer. Mol Cancer Ther. 2015 May; 14(5):1117-29.
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D'Alessandro A, Marrocco C, Rinalducci S, Peschiaroli A, Timperio AM, Bongiorno-Borbone L, Finazzi Agr? A, Melino G, Zolla L. Analysis of TAp73-dependent signaling via omics technologies. J Proteome Res. 2013 Sep 06; 12(9):4207-20.
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Gallant-Behm CL, Espinosa JM. ?Np63a utilizes multiple mechanisms to repress transcription in squamous cell carcinoma cells. Cell Cycle. 2013 Feb 01; 12(3):409-16.
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Brandt T, Kaar JL, Fersht AR, Veprintsev DB. Stability of p53 homologs. PLoS One. 2012; 7(10):e47889.
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Ozono E, Komori H, Iwanaga R, Tanaka T, Sakae T, Kitamura H, Yamaoka S, Ohtani K. Tumor suppressor TAp73 gene specifically responds to deregulated E2F activity in human normal fibroblasts. Genes Cells. 2012 Aug; 17(8):660-72.
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Siegenthaler JA, Miller MW. Generation of Cajal-Retzius neurons in mouse forebrain is regulated by transforming growth factor beta-Fox signaling pathways. Dev Biol. 2008 Jan 01; 313(1):35-46.
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Shapiro GS, Van Peursem C, Ornelles DA, Schaack J, DeGregori J. Recombinant adenoviral vectors can induce expression of p73 via the E4-orf6/7 protein. J Virol. 2006 Jun; 80(11):5349-60.
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Lang GA, Iwakuma T, Suh YA, Liu G, Rao VA, Parant JM, Valentin-Vega YA, Terzian T, Caldwell LC, Strong LC, El-Naggar AK, Lozano G. Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. Cell. 2004 Dec 17; 119(6):861-72.
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Chau BN, Chen TT, Wan YY, DeGregori J, Wang JY. Tumor necrosis factor alpha-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation. Mol Cell Biol. 2004 May; 24(10):4438-47.
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