 CD8-Positive T-Lymphocytes
"CD8-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes.
| Descriptor ID |
D018414
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| MeSH Number(s) |
A11.118.637.555.567.569.220 A15.145.229.637.555.567.569.220 A15.382.490.555.567.569.220
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| Concept/Terms |
CD8-Positive T-Lymphocytes- CD8-Positive T-Lymphocytes
- CD8 Positive T Lymphocytes
- CD8-Positive T-Lymphocyte
- T-Lymphocyte, CD8-Positive
- T-Lymphocytes, CD8-Positive
- T8 Lymphocytes
- Lymphocyte, T8
- Lymphocytes, T8
- T8 Lymphocyte
- T8 Cells
- Cell, T8
- Cells, T8
- T8 Cell
- CD8-Positive Lymphocytes
- CD8 Positive Lymphocytes
- CD8-Positive Lymphocyte
- Lymphocyte, CD8-Positive
- Lymphocytes, CD8-Positive
Suppressor T-Lymphocytes, CD8-Positive- Suppressor T-Lymphocytes, CD8-Positive
- CD8-Positive Suppressor T-Lymphocyte
- CD8-Positive Suppressor T-Lymphocytes
- Suppressor T Lymphocytes, CD8 Positive
- Suppressor T-Lymphocyte, CD8-Positive
- T-Lymphocyte, CD8-Positive Suppressor
- T-Lymphocytes, CD8-Positive Suppressor
- Suppressor T-Cells, CD8-Positive
- CD8-Positive Suppressor T-Cell
- CD8-Positive Suppressor T-Cells
- Suppressor T Cells, CD8 Positive
- Suppressor T-Cell, CD8-Positive
- T-Cell, CD8-Positive Suppressor
- T-Cells, CD8-Positive Suppressor
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Below are MeSH descriptors whose meaning is more general than "CD8-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD8-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD8-Positive T-Lymphocytes" by people in this website by year, and whether "CD8-Positive T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 | | 1996 | 2 | 3 | 5 | | 1997 | 3 | 1 | 4 | | 1998 | 3 | 2 | 5 | | 1999 | 3 | 3 | 6 | | 2000 | 4 | 1 | 5 | | 2001 | 5 | 4 | 9 | | 2002 | 9 | 4 | 13 | | 2003 | 7 | 2 | 9 | | 2004 | 5 | 6 | 11 | | 2005 | 10 | 6 | 16 | | 2006 | 10 | 11 | 21 | | 2007 | 13 | 9 | 22 | | 2008 | 10 | 10 | 20 | | 2009 | 9 | 6 | 15 | | 2010 | 13 | 2 | 15 | | 2011 | 8 | 6 | 14 | | 2012 | 11 | 5 | 16 | | 2013 | 16 | 8 | 24 | | 2014 | 17 | 11 | 28 | | 2015 | 12 | 7 | 19 | | 2016 | 19 | 16 | 35 | | 2017 | 15 | 5 | 20 | | 2018 | 15 | 15 | 30 | | 2019 | 17 | 14 | 31 | | 2020 | 17 | 10 | 27 | | 2021 | 16 | 17 | 33 | | 2022 | 6 | 14 | 20 | | 2023 | 10 | 17 | 27 | | 2024 | 20 | 13 | 33 | | 2025 | 14 | 8 | 22 |
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Below are the most recent publications written about "CD8-Positive T-Lymphocytes" by people in Profiles.
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Albert GK, Cao P, Davila E. Leveraging innate immune signals in CD8+ T cells to boost antitumor immunity. Front Immunol. 2025; 16:1617773.
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Kang T, Usherwood YK, Reisz JA, Kamerkar SC, Culp-Hill R, Wilkins OM, Verissimo AF, Kolling FW, Hung AM, Musial SC, Rosato PC, D'Alessandro A, Higgs HN, Usherwood EJ. Targeting pyruvate metabolism generates distinct CD8+ T cell responses to gammaherpesvirus and B lymphoma. JCI Insight. 2025 Aug 22; 10(16).
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Nagaoka K, Nakanishi H, Tanaka H, Anindita J, Kawamura T, Tanaka T, Yamashita T, Kuroda A, Nomura S, Akita H, Itaka K, Kodama T, Kakimi K. Neoantigen mRNA vaccines induce progenitor-exhausted T cells that support anti-PD-1 therapy in gastric cancer with peritoneal metastasis. Gastric Cancer. 2025 Sep; 28(5):825-836.
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Chia SB, Johnson BJ, Hu J, Valença-Pereira F, Chadeau-Hyam M, Guntoro F, Montgomery H, Boorgula MP, Sreekanth V, Goodspeed A, Davenport B, De Dominici M, Zaberezhnyy V, Schleicher WE, Gao D, Cadar AN, Petriz-Otaño L, Papanicolaou M, Beheshti A, Baylin SB, Guarnieri JW, Wallace DC, Costello JC, Bartley JM, Morrison TE, Vermeulen R, Aguirre-Ghiso JA, Rincon M, DeGregori J. Respiratory viral infections awaken metastatic breast cancer cells in lungs. Nature. 2025 Sep; 645(8080):496-506.
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Devi KSP, Wang E, Jaiswal A, Konieczny P, Kim TG, Nirschl CJ, Verma A, Liu Y, Milczanowski J, Christo SN, Gandolfo LC, Haitz K, Vardam TD, Wu P, King SL, Tse SW, Pradhan K, Jiang X, Tian T, Fuhlbrigge RC, Schmults CD, Clark RA, Kupper TS, Freeman GJ, Mackay LK, Naik S, Newell EW, Elemento O, Suarez-Farinas M, Anandasabapathy N. PD-1 is requisite for skin TRM cell formation and specification by TGFß. Nat Immunol. 2025 Aug; 26(8):1339-1351.
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Lim L, Jonsson AH. CD8+?T Cells You Should Know about in Autoimmunity: Current Paradigms of T Cell Pathogenesis in Autoimmune Disease. Curr Allergy Asthma Rep. 2025 Jul 26; 25(1):31.
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van der Heide V, Laghlali G, Davenport B, Cubitt B, Roudko V, Choo D, Jhun K, Humblin E, Vaidya A, Angeliadis K, Dawson T, Furtado G, Kamphorst AO, Schotsaert M, Ahmed R, de la Torre JC, Homann D. Prolonged but finite antigen presentation promotes reversible defects of "helpless" memory CD8+ T cells. Immunity. 2025 Jul 08; 58(7):1742-1761.e14.
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Cabrera-Martinez B, Garcia-Perez JE, Baxter RM, Lui VG, Ghosh T, Eken A, Kostka-Newman Z, Garcia JRM, Rahkola J, Gessner RL, Dutmer CM, Klarquist J, Pietras EM, Ghosh D, Johnson SA, Kedl RM, Hsieh EWY. A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rß deficiency. Cell Rep. 2025 Jul 22; 44(7):115902.
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Horisberger A, Griffith A, Keegan J, Arazi A, Pulford J, Murzin E, Howard K, Hancock B, Fava A, Sasaki T, Ghosh T, Inamo J, Beuschel R, Cao Y, Preisinger K, Gutierrez-Arcelus M, Eisenhaure TM, Guthridge J, Hoover PJ, Dall'Era M, Wofsy D, Kamen DL, Kalunian KC, Furie R, Belmont M, Izmirly P, Clancy R, Hildeman D, Woodle ES, Apruzzese W, McMahon MA, Grossman J, Barnas JL, Payan-Schober F, Ishimori M, Weisman M, Kretzler M, Berthier CC, Hodgin JB, Demeke DS, Putterman C, Brenner MB, Anolik JH, Raychaudhuri S, Hacohen N, James JA, Davidson A, Petri MA, Buyon JP, Diamond B, Zhang F, Lederer JA, Rao DA. Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis. J Clin Invest. 2025 Aug 15; 135(16).
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Lanzar ZR, Aldridge DL, Jayaraman B, Haskins B, Howard CA, Arana K, Bunkofske ME, Mulka K, Pardy RD, Byerly J, Striepen B, Lupardus P, Hunter CA. De-coupling immune parameters and toxicity associated with IL-12 agonism. Cell Rep. 2025 Jun 24; 44(6):115840.
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