 CD8-Positive T-Lymphocytes
"CD8-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes.
| Descriptor ID |
D018414
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| MeSH Number(s) |
A11.118.637.555.567.569.220 A15.145.229.637.555.567.569.220 A15.382.490.555.567.569.220
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| Concept/Terms |
CD8-Positive T-Lymphocytes- CD8-Positive T-Lymphocytes
- CD8 Positive T Lymphocytes
- CD8-Positive T-Lymphocyte
- T-Lymphocyte, CD8-Positive
- T-Lymphocytes, CD8-Positive
- T8 Lymphocytes
- Lymphocyte, T8
- Lymphocytes, T8
- T8 Lymphocyte
- T8 Cells
- Cell, T8
- Cells, T8
- T8 Cell
- CD8-Positive Lymphocytes
- CD8 Positive Lymphocytes
- CD8-Positive Lymphocyte
- Lymphocyte, CD8-Positive
- Lymphocytes, CD8-Positive
Suppressor T-Lymphocytes, CD8-Positive- Suppressor T-Lymphocytes, CD8-Positive
- CD8-Positive Suppressor T-Lymphocyte
- CD8-Positive Suppressor T-Lymphocytes
- Suppressor T Lymphocytes, CD8 Positive
- Suppressor T-Lymphocyte, CD8-Positive
- T-Lymphocyte, CD8-Positive Suppressor
- T-Lymphocytes, CD8-Positive Suppressor
- Suppressor T-Cells, CD8-Positive
- CD8-Positive Suppressor T-Cell
- CD8-Positive Suppressor T-Cells
- Suppressor T Cells, CD8 Positive
- Suppressor T-Cell, CD8-Positive
- T-Cell, CD8-Positive Suppressor
- T-Cells, CD8-Positive Suppressor
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Below are MeSH descriptors whose meaning is more general than "CD8-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD8-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD8-Positive T-Lymphocytes" by people in this website by year, and whether "CD8-Positive T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 2 | 3 | 5 | | 1997 | 3 | 1 | 4 | | 1998 | 3 | 2 | 5 | | 1999 | 3 | 3 | 6 | | 2000 | 4 | 1 | 5 | | 2001 | 5 | 4 | 9 | | 2002 | 9 | 4 | 13 | | 2003 | 4 | 2 | 6 | | 2004 | 5 | 7 | 12 | | 2005 | 9 | 6 | 15 | | 2006 | 8 | 10 | 18 | | 2007 | 11 | 9 | 20 | | 2008 | 11 | 10 | 21 | | 2009 | 9 | 6 | 15 | | 2010 | 10 | 2 | 12 | | 2011 | 7 | 6 | 13 | | 2012 | 11 | 5 | 16 | | 2013 | 16 | 8 | 24 | | 2014 | 16 | 11 | 27 | | 2015 | 13 | 7 | 20 | | 2016 | 19 | 16 | 35 | | 2017 | 15 | 7 | 22 | | 2018 | 15 | 16 | 31 | | 2019 | 17 | 14 | 31 | | 2020 | 17 | 11 | 28 | | 2021 | 15 | 17 | 32 | | 2022 | 5 | 15 | 20 | | 2023 | 10 | 17 | 27 | | 2024 | 16 | 14 | 30 | | 2025 | 20 | 11 | 31 | | 2026 | 8 | 2 | 10 |
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Below are the most recent publications written about "CD8-Positive T-Lymphocytes" by people in Profiles.
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Kendirli PK, Erdem S, Kisaarslan AP, Gök V, Kayhan E, Özcan A, Dogan ME, Klein C, Ünal E, Eken A. A novel ELF4 gene variant disrupts T and NK cell function in a patient with immune thrombocytopenia (ITP). Inflamm Res. 2026 May 19; 75(1).
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Berger JN, Rosales A, Heiden D, Merrick C, Monogue B, Beckham JD, Berg L. Myeloid cell IL-15 production in the brain supports bystander CD8+ T cell neuropathic immune responses following virus infection. J Immunol. 2026 May 14; 215(5).
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Bermack C, Singh S, Pei G, Patel SP, Wang L, Yee C. First-in-human use of recombinant IL-7 to potentiate antigen-specific T cell therapy: a single patient case study. J Immunother Cancer. 2026 Apr 30; 14(4).
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Buckley DJ, Zahedi S, Canizales A, Cuellar NE, Bogale K, Smith KA, Terrebonne KJ, Sharma S, Joseph B, Greaney JL, Trott DW. CD8+ T cells contribute to arterial aging in mice. J Immunol. 2026 Apr 15; 215(4).
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DiLisio JE, Beard KS, Neef T, Miller SD, Wenzlau JM, Nakayama M, D'Antonio MA, Jamison BL, Nicholson KS, Baker RL, Brunetti TM, Gapin L, Haskins K. Antigen-specific immunotherapy with a CD4+ T cell neoepitope restrains CD8+ T cell differentiation in murine pancreatic islet grafts. Nat Commun. 2026 Mar 24; 17(1).
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Hoyt-Miggelbrink AM, Waibl Polania J, Wachsmuth L, Lorrey S, Mohan A, Hardigan A, Blandford E, Lerner E, Wilkinson D, Hotchkiss KM, Cook S, Hemmers S, Patel A, Ayasoufi K, Fecci P. Upregulation of TNFR2 Precedes TOX Expression by Exhausted T cells and Restricts Antitumor and Antiviral Immunity. Clin Cancer Res. 2026 Feb 17; 32(4):782-800.
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Mann BT, Sanz M, Chitrakar A, Langlands K, Siegel M, Soriano-Sarabia N. Ex vivo-expanded allogeneic Vd2 T cells specifically reduce reservoirs of HIV-1 following latency reversal. JCI Insight. 2026 Mar 23; 11(6).
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Kantheti U, Shirley JL, Fry LG, Qvale AM, Olivas-Corral JG, Vankamamidi SE, Tamburini BAJ. PD-L1 cell-intrinsic signals limit immune activation during cutaneous vaccinia virus infection. J Immunol. 2026 Feb 09; 215(2).
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Lenkala D, Kohler J, McCarthy B, Nelson M, Bakker NAM, de Boer R, Jackson EK, Sheen JHF, Hannes S, Esaulova E, Stewart K, Gottstein C, Attanasio J, Brown FD, Hymson S, Meda S, van Zon M, Scheij S, Voogd R, Raud B, Xu Z, Borgers JSW, Rohaan MW, Balogh KN, Poran A, Rooney M, Dong JZ, Srouji JR, Juneja VR, Arieta CM, Nijenhuis CM, Nuijen B, DeMario M, Manson K, Schumacher TNM, Gaynor RB, Haanen JB, van den Berg JH, van Buuren MM. NEO-STIM advances personalized neoantigen-specific adoptive T cell therapy. Nat Commun. 2026 Feb 05; 17(1).
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Yamauchi T, Luo Y, Menon DR, Couts K, Khan S, Goel A, Dinarello CA, Zhai Z, Fujita M. Human Alpha-1 Antitrypsin Suppresses Melanoma Growth by Promoting Tumor Differentiation and CD8+ T-Cell-Mediated Immunity. Biomolecules. 2026 Jan 12; 16(1).
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