 Mice, SCID
"Mice, SCID" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.
| Descriptor ID |
D016513
|
| MeSH Number(s) |
B01.050.150.900.649.313.992.635.505.500.550.780
|
| Concept/Terms |
Mice, SCID- Mice, SCID
- Severe Combined Immunodeficient Mice
- SCID Mice
- Immunodeficient Mice, Severe Combined
- Mouse, SCID
- SCID Mouse
Mouse, SCID-hu- Mouse, SCID-hu
- Mouse, SCID hu
- SCID-hu Mouse
- SCID-hu Mice
- Mice, SCID-hu
- SCID hu Mice
|
Below are MeSH descriptors whose meaning is more general than "Mice, SCID".
Below are MeSH descriptors whose meaning is more specific than "Mice, SCID".
This graph shows the total number of publications written about "Mice, SCID" by people in this website by year, and whether "Mice, SCID" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 4 | 4 | | 1996 | 0 | 3 | 3 | | 1998 | 0 | 2 | 2 | | 2000 | 0 | 7 | 7 | | 2001 | 0 | 3 | 3 | | 2002 | 0 | 9 | 9 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 7 | 7 | | 2005 | 0 | 16 | 16 | | 2006 | 0 | 7 | 7 | | 2007 | 0 | 9 | 9 | | 2008 | 0 | 11 | 11 | | 2009 | 0 | 10 | 10 | | 2010 | 0 | 11 | 11 | | 2011 | 0 | 5 | 5 | | 2012 | 0 | 12 | 12 | | 2013 | 0 | 12 | 12 | | 2014 | 0 | 8 | 8 | | 2015 | 0 | 11 | 11 | | 2016 | 0 | 10 | 10 | | 2017 | 0 | 11 | 11 | | 2018 | 0 | 14 | 14 | | 2019 | 0 | 9 | 9 | | 2020 | 0 | 11 | 11 | | 2021 | 0 | 8 | 8 | | 2022 | 0 | 5 | 5 | | 2023 | 0 | 1 | 1 | | 2024 | 0 | 5 | 5 | | 2025 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Mice, SCID" by people in Profiles.
-
Ma J, Wang Z, Mintzlaff D, Zhang H, Ramakrishna R, Davila E, Witkowski MT, Lucia MS, Schwartz MS, Pomfret EA, Mathes DW, Wang Z. Bivalent CD47 immunotoxin for targeted therapy of T-cell acute lymphoblastic leukemia. Blood. 2025 Jan 30; 145(5):508-519.
-
Hamilton AK, Radaoui AB, Tsang M, Martinez D, Conkrite KL, Patel K, Sidoli S, Delaidelli A, Modi A, Rokita JL, Lane MV, Hartnett N, Lopez RD, Zhang B, Zhong C, Ennis B, Miller DP, Brown MA, Rathi KS, Raman P, Pogoriler J, Bhatti T, Pawel B, Glisovic-Aplenc T, Teicher B, Erickson SW, Earley EJ, Bosse KR, Sorensen PH, Krytska K, Mosse YP, Havenith KE, Zammarchi F, van Berkel PH, Smith MA, Garcia BA, Maris JM, Diskin SJ. A proteogenomic surfaceome study identifies DLK1 as an immunotherapeutic target in neuroblastoma. Cancer Cell. 2024 Nov 11; 42(11):1970-1982.e7.
-
White TD, Almutairi A, Gai-Tusing Y, Stephenson DJ, Stephenson BD, Chalfant CE, Lei X, Lu B, Hammock BD, DiLorenzo TP, Ramanadham S. Differential lipid signaling from CD4+ and CD8+ T cells contributes to type 1 diabetes development. Front Immunol. 2024; 15:1444639.
-
Whiteley AE, Ma D, Wang L, Yu SY, Yin C, Price TT, Simon BG, Xu KR, Marsh KA, Brockman ML, Prioleau TM, Zhou KI, Cui X, Fecci PE, Jeck WR, McCall CM, Neff JL, Sipkins DA. Breast cancer exploits neural signaling pathways for bone-to-meninges metastasis. Science. 2024 06 21; 384(6702):eadh5548.
-
Wang Z, Ramakrishna R, Wang Y, Qiu Y, Ma J, Mintzlaff D, Zhang H, Li B, Hammell B, Lucia MS, Pomfret E, Su AA, Washington KM, Mathes DW, Wang Z. Toxicology, pharmacokinetics, and immunogenicity studies of CCR4-IL2 bispecific immunotoxin in rats and minipigs. Eur J Pharmacol. 2024 Apr 05; 968:176408.
-
Randall J, Evans K, Watts B, Kosasih HJ, Smith CM, Earley EJ, Erickson SW, Jocoy EL, Bult CJ, Teicher BA, de Bock CE, Smith MA, Lock RB. In vivo activity of the second-generation proteasome inhibitor ixazomib against pediatric T-cell acute lymphoblastic leukemia xenografts. Exp Hematol. 2024 Apr; 132:104176.
-
Pires EM, Pugazhenthi U, Fink MK, Habenicht LM, Fong DL, Leszczynski JK, Schurr MJ, Manuel CA. Antibiotic Treatment of Corynebacterium bovis-associated Clinical Disease in NSG Mice. Comp Med. 2023 Dec 01; 73(6):461-465.
-
Manuel CA, Pearson EC, Pugazhenthi U, Fink MK, Habenicht LM, Fong DL, Leszczynski JK, Schurr MJ. A Clinical Scoring Systems for the Evaluation of Corynebacterium bovis -associated Disease in NSG Mice. Comp Med. 2022 12 01; 72(6):386-393.
-
Kim YK, Walters JA, Moss ND, Wells KL, Sheridan R, Miranda JG, Benninger RKP, Pyle LL, O'Brien RM, Sussel L, Davidson HW. Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration. Mol Metab. 2022 12; 66:101632.
-
Sureshchandra S, Chan CN, Robino JJ, Parmelee LK, Nash MJ, Wesolowski SR, Pietras EM, Friedman JE, Takahashi D, Shen W, Jiang X, Hennebold JD, Goldman D, Packwood W, Lindner JR, Roberts CT, Burwitz BJ, Messaoudi I, Varlamov O. Maternal Western-style diet remodels the transcriptional landscape of fetal hematopoietic stem and progenitor cells in rhesus macaques. Stem Cell Reports. 2022 12 13; 17(12):2595-2609.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|