 S Phase
"S Phase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phase of the CELL CYCLE following G1 and preceding G2 when the entire DNA content of the nucleus is replicated. It is achieved by bidirectional replication at multiple sites along each chromosome.
| Descriptor ID |
D016196
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| MeSH Number(s) |
G02.111.225.880 G04.144.500.800 G05.226.880
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| Concept/Terms |
S Phase- S Phase
- Phase, S
- Phases, S
- S Phases
- S Period
- Period, S
- Periods, S
- S Periods
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Below are MeSH descriptors whose meaning is more general than "S Phase".
Below are MeSH descriptors whose meaning is more specific than "S Phase".
This graph shows the total number of publications written about "S Phase" by people in this website by year, and whether "S Phase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 3 | 4 | | 1997 | 0 | 2 | 2 | | 1998 | 1 | 3 | 4 | | 1999 | 1 | 2 | 3 | | 2000 | 1 | 1 | 2 | | 2001 | 0 | 2 | 2 | | 2002 | 1 | 3 | 4 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 3 | 3 | | 2005 | 1 | 3 | 4 | | 2006 | 1 | 2 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 3 | 5 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 6 | 6 | | 2011 | 0 | 6 | 6 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 2 | 2 | | 2014 | 0 | 2 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 2 | 1 | 3 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 2 | 2 | | 2024 | 2 | 0 | 2 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "S Phase" by people in Profiles.
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Wu G, Taylor E, Youmans DT, Arnoult N, Cech TR. Rapid dynamics allow the low-abundance RTEL1 helicase to promote telomere replication. Nucleic Acids Res. 2025 Feb 27; 53(5).
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Dreyer J, Ricci G, van den Berg J, Bhardwaj V, Funk J, Armstrong C, van Batenburg V, Sine C, VanInsberghe MA, Tjeerdsma RB, Marsman R, Mandemaker IK, di Sanzo S, Costantini J, Manzo SG, Biran A, Burny C, van Vugt MATM, Völker-Albert M, Groth A, Spencer SL, van Oudenaarden A, Mattiroli F. Acute multi-level response to defective de novo chromatin assembly in S-phase. Mol Cell. 2024 Dec 19; 84(24):4711-4728.e10.
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Holtzen SE, Navid E, Kainov JD, Palmer AE. Transient Zn2+ deficiency induces replication stress and compromises daughter cell proliferation. Proc Natl Acad Sci U S A. 2024 May 07; 121(19):e2321216121.
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Knudsen ES, Witkiewicz AK, Rubin SM. Cancer takes many paths through G1/S. Trends Cell Biol. 2024 08; 34(8):636-645.
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Armstrong C, Passanisi VJ, Ashraf HM, Spencer SL. Cyclin E/CDK2 and feedback from soluble histone protein regulate the S phase burst of histone biosynthesis. Cell Rep. 2023 07 25; 42(7):112768.
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Whetstine JR, Van Rechem C. Protocol to isolate cells in four stages of S phase for high-resolution replication-timing sequencing. STAR Protoc. 2022 03 18; 3(1):101209.
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Van Rechem C, Ji F, Chakraborty D, Black JC, Sadreyev RI, Whetstine JR. Collective regulation of chromatin modifications predicts replication timing during cell cycle. Cell Rep. 2021 10 05; 37(1):109799.
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Ganapathi Sankaran D, Stemm-Wolf AJ, Pearson CG. CEP135 isoform dysregulation promotes centrosome amplification in breast cancer cells. Mol Biol Cell. 2019 05 01; 30(10):1230-1244.
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Wu X, An X, Zhang C, Huang M. Clb6-Cdc28 Promotes Ribonucleotide Reductase Subcellular Redistribution during S Phase. Mol Cell Biol. 2018 03 15; 38(6).
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Rossbach D, Bryan DS, Hesselberth JR, Sclafani R. Localization of Cdc7 Protein Kinase During DNA Replication in Saccharomyces cerevisiae. G3 (Bethesda). 2017 11 06; 7(11):3757-3774.
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