 Neurofilament Proteins
"Neurofilament Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Type III intermediate filament proteins that assemble into neurofilaments, the major cytoskeletal element in nerve axons and dendrites. They consist of three distinct polypeptides, the neurofilament triplet. Types I, II, and IV intermediate filament proteins form other cytoskeletal elements such as keratins and lamins. It appears that the metabolism of neurofilaments is disturbed in Alzheimer's disease, as indicated by the presence of neurofilament epitopes in the neurofibrillary tangles, as well as by the severe reduction of the expression of the gene for the light neurofilament subunit of the neurofilament triplet in brains of Alzheimer's patients. (Can J Neurol Sci 1990 Aug;17(3):302)
| Descriptor ID |
D016900
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| MeSH Number(s) |
D05.750.078.593.630 D12.776.220.475.630 D12.776.631.630
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Neurofilament Proteins".
Below are MeSH descriptors whose meaning is more specific than "Neurofilament Proteins".
This graph shows the total number of publications written about "Neurofilament Proteins" by people in this website by year, and whether "Neurofilament Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 1 | 1 | 2 | | 2003 | 2 | 1 | 3 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 2 | 0 | 2 | | 2011 | 1 | 0 | 1 | | 2013 | 2 | 1 | 3 | | 2014 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 4 | 0 | 4 | | 2025 | 1 | 8 | 9 | | 2026 | 1 | 3 | 4 |
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Below are the most recent publications written about "Neurofilament Proteins" by people in Profiles.
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Pauley ME, Coughlan C, Dong F, Bucca B, Tanner B, Chartier-Logan C, Shapiro ALB, Snell-Bergeon JK. Type 1 diabetes is associated with higher plasma levels of biomarkers of neurodegeneration and neuroinflammation. Front Immunol. 2026; 17:1860993.
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Ridgeway K, Dastgheyb RM, Easter RE, Shorer EF, Anok A, Tomusange S, Mannarino J, Saylor D, Gisslen M, Zetterberg H, Nakasujja N, Nakigozi G, Paul R, Rubin LH. Cognitive and sensorimotor impairments in virally suppressed people with and without HIV in Uganda: Associations with neurofilament light chain as a biomarker of neuronal injury. J Neurovirol. 2026 Jun 22; 32(4).
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Meletti S, Hanin A, Giovannini G, Bedin R, Burani M, Taruffi L, Orlandi N, Urbano T, D'Achille F, Malerba M, Basha MM, Eschbach K, Foreman B, Farias-Moeller R, Gaspard N, Gerard EE, Gofton T, Gopaul MT, Haider HA, Hantus ST, Herman S, Kang P, Day GS, Kandula P, Steriade C, Struck AF, Taraschenko O, Wainwright M, Yoo JY, Zhou DJ, Lattanzi S, Navarro V, Hirsch LJ. Acute Brain Injury in New-Onset Refractory Status Epilepticus and Etiology-Defined Status Epilepticus. JAMA Neurol. 2026 Jun 01; 83(6):563-572.
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Hanin A, Marois C, Guillemaud M, Chavez M, Cosme L, Hayatou Z, Besnard A, Goudard G, Masson V, Cousyn L, Cheval M, Denis JA, Alkouri R, Lamari F, Bisulli F, Eschbach K, Farias-Moeller R, Gaspard N, Gerard EE, Giovannini G, Gofton T, Gopaul MT, Kellogg M, Meletti S, Muccioli L, Pasini E, Taraschenko O, Torcida N, Wainwright MS, Yoo JY, Wong N, Bonnefont-Rousselot D, Demeret S, Hirsch LJ, Navarro V. Exploring pathways leading to drug-resistant epilepsy for patients with cryptogenic new onset refractory status epilepticus. Epilepsia. 2026 May; 67(5):2326-2346.
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Sillau SH, Coughlan C, Ahmed MM, Nair K, Araya P, Galbraith MD, Ritchie A, Ching-Jung Wang A, Elos MT, Bettcher BM, Espinosa JM, Chial HJ, Epperson N, Boyd TD, Potter H. Blood measure of neuronal death is exponentially higher with age, especially in females, and halted in Alzheimer's disease by GM-CSF treatment. Cell Rep Med. 2026 Jan 20; 7(1):102525.
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Hoisington AJ, Stamper CE, Sullan M, Brenner LA, Burnham EL, Najarro KM, Idrovo JP, Wiktor AJ, Vogler T, Halevi A, McMahan RH, Kovacs EJ. Measurement of Central Nervous System-Related Biomarkers in Plasma of Burn Patients. Shock. 2026 Aug 01; 66(2):462-468.
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Krivickas B, Scirocco E, Giacomelli E, Sharma S, Benson M, Keegan M, Kulesa-Kelley J, Chibnik LB, Casagrande G, Heyd L, Chase M, Drake K, Mohapatra S, Hagar JL, Hasenoehrl MG, Dagostino D, Sherman AV, Leite A, Yu H, Rosenthal J, Miller T, McCaffrey A, Gwathmey K, Locatelli E, Bayat E, Heitzman D, Young E, Goyal NA, Whitesell J, Felice K, Ilieva H, Swenson A, Walk D, Alameda G, Foster L, McIlduff CE, Walsh A, Zilliox L, Ajroud-Driss S, Bodkin C, Katz J, Ladha S, Rivner M, Rosow L, Twydell P, Wasiewski W, Babu S, Berry JD, Paganoni S. Multicenter Expanded Access Protocol for Research Through Access to Trehalose in People With Amyotrophic Lateral Sclerosis. Muscle Nerve. 2025 Nov; 72(5):1108-1116.
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Vugmeyster L, Frazier B, Fu R, Ostrovsky D. Multi-mode water dynamics in hydration shells of villin headpiece subdomain protein in the solid state using deuterium and oxygen-17 NMR spectroscopy. J Chem Phys. 2025 Jul 14; 163(2).
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Garcia-Cordero I, Vargas-Gonzalez JC, Hadian M, Bayram E, Rodriguez-Porcel F, Couto B, Iyer J, Golbe LI, Stephen CD, Pantelyat A, Dale ML, McFarland N, Xie T, Swan M, Kang K, Gunzler D, Wills AM, Boxer A, Litvan I, Lang A, Tartaglia MC. Language impairment is associated with faster progression in progressive supranuclear palsy-Richardson syndrome. Alzheimers Dement. 2025 07; 21(7):e70485.
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Janas AM, Miller KR, Ceschin R, Mourani PM, Ruzas CM, Bennett TD, Fink EL, Maddux AB. Early Blood Biomarkers and MRI Injury After Cardiac Arrest: Secondary Analysis of the 2017-2020 Personalized Outcomes After Child Cardiac Arrest Study. Pediatr Crit Care Med. 2025 Jul 01; 26(7):e915-e923.
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