 Proto-Oncogene Proteins c-jun
"Proto-Oncogene Proteins c-jun" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cellular DNA-binding proteins encoded by the c-jun genes (GENES, JUN). They are involved in growth-related transcriptional control. There appear to be three distinct functions: dimerization (with c-fos), DNA-binding, and transcriptional activation. Oncogenic transformation can take place by constitutive expression of c-jun.
| Descriptor ID |
D016755
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| MeSH Number(s) |
D12.776.260.108.820 D12.776.624.664.700.182 D12.776.660.763 D12.776.930.127.820
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| Concept/Terms |
Proto-Oncogene Proteins c-jun- Proto-Oncogene Proteins c-jun
- Proto Oncogene Proteins c jun
- c-jun Proteins
- c jun Proteins
- fos-Associated Protein p39
- fos Associated Protein p39
- jun Proto-Oncogene Product p39
- jun Proto Oncogene Product p39
- jun Proto-Oncogene Proteins
- jun Proto Oncogene Proteins
- p39 c-jun
- p39 c jun
- p39(c-jun)
- Proto-Oncogene Products c-jun
- Proto Oncogene Products c jun
- c-fos-Associated Protein p39
- c fos Associated Protein p39
- Proto-Oncogene Proteins jun
- Proto Oncogene Proteins jun
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-jun".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-jun".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-jun" by people in this website by year, and whether "Proto-Oncogene Proteins c-jun" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 1 | 3 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 2 | 2 | 4 | | 2005 | 2 | 1 | 3 | | 2006 | 0 | 2 | 2 | | 2008 | 2 | 1 | 3 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 2 | 3 | | 2011 | 0 | 1 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-jun" by people in Profiles.
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Grayck MR, McCarthy WC, Solar M, Balasubramaniyan N, Zheng L, Orlicky DJ, Wright CJ. Implications of neonatal absence of innate immune mediated NF?B/AP1 signaling in the murine liver. Pediatr Res. 2024 Jun; 95(7):1791-1802.
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Cheng TC, Philip JL, Tabima DM, Kumari S, Yakubov B, Frump AL, Hacker TA, Bellofiore A, Li R, Sun X, Goss KN, Lahm T, Chesler NC. Estrogen receptor-a prevents right ventricular diastolic dysfunction and fibrosis in female rats. Am J Physiol Heart Circ Physiol. 2020 12 01; 319(6):H1459-H1473.
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Kessler BE, Mishall KM, Kellett MD, Clark EG, Pugazhenthi U, Pozdeyev N, Kim J, Tan AC, Schweppe RE. Resistance to Src inhibition alters the BRAF-mutant tumor secretome to promote an invasive phenotype and therapeutic escape through a FAK>p130Cas>c-Jun signaling axis. Oncogene. 2019 04; 38(14):2565-2579.
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Fechtner S, Singh A, Chourasia M, Ahmed S. Molecular insights into the differences in anti-inflammatory activities of green tea catechins on IL-1? signaling in rheumatoid arthritis synovial fibroblasts. Toxicol Appl Pharmacol. 2017 08 15; 329:112-120.
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Pratt EP, Owens JL, Hockerman GH, Hu CD. Bimolecular Fluorescence Complementation (BiFC) Analysis of Protein-Protein Interactions and Assessment of Subcellular Localization in Live Cells. Methods Mol Biol. 2016; 1474:153-70.
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Walters RD, McSwiggen DT, Goodrich JA, Kugel JF. Selection and characterization of a DNA aptamer that can discriminate between cJun/cJun and cJun/cFos. PLoS One. 2014; 9(6):e101015.
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Zhang H, Yu C, Dai J, Keller JM, Hua A, Sottnik JL, Shelley G, Hall CL, Park SI, Yao Z, Zhang J, McCauley LK, Keller ET. Parathyroid hormone-related protein inhibits DKK1 expression through c-Jun-mediated inhibition of ?-catenin activation of the DKK1 promoter in prostate cancer. Oncogene. 2014 May 08; 33(19):2464-77.
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Walters RD, Drullinger LF, Kugel JF, Goodrich JA. NFATc2 recruits cJun homodimers to an NFAT site to synergistically activate interleukin-2 transcription. Mol Immunol. 2013 Nov; 56(1-2):48-56.
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Patel N, Klassert TE, Greco SJ, Patel SA, Munoz JL, Reddy BY, Bryan M, Campbell N, Kokorina N, Sabaawy HE, Rameshwar P. Developmental regulation of TAC1 in peptidergic-induced human mesenchymal stem cells: implication for spinal cord injury in zebrafish. Stem Cells Dev. 2012 Jan 20; 21(2):308-20.
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Ranji A, Shkriabai N, Kvaratskhelia M, Musier-Forsyth K, Boris-Lawrie K. Features of double-stranded RNA-binding domains of RNA helicase A are necessary for selective recognition and translation of complex mRNAs. J Biol Chem. 2011 Feb 18; 286(7):5328-37.
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