Complement System Proteins
"Complement System Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serum glycoproteins participating in the host defense mechanism of COMPLEMENT ACTIVATION that creates the COMPLEMENT MEMBRANE ATTACK COMPLEX. Included are glycoproteins in the various pathways of complement activation (CLASSICAL COMPLEMENT PATHWAY; ALTERNATIVE COMPLEMENT PATHWAY; and LECTIN COMPLEMENT PATHWAY).
Descriptor ID |
D003165
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MeSH Number(s) |
D12.776.124.486.274
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Concept/Terms |
Complement System Proteins- Complement System Proteins
- Proteins, Complement System
- Complement Protein
- Protein, Complement
- Complement Proteins
- Proteins, Complement
- Complement
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Below are MeSH descriptors whose meaning is more general than "Complement System Proteins".
Below are MeSH descriptors whose meaning is more specific than "Complement System Proteins".
This graph shows the total number of publications written about "Complement System Proteins" by people in this website by year, and whether "Complement System Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 | 1995 | 1 | 0 | 1 | 1996 | 1 | 0 | 1 | 1997 | 1 | 1 | 2 | 1998 | 2 | 0 | 2 | 1999 | 2 | 0 | 2 | 2000 | 1 | 0 | 1 | 2002 | 1 | 0 | 1 | 2004 | 2 | 2 | 4 | 2005 | 1 | 0 | 1 | 2006 | 2 | 2 | 4 | 2007 | 2 | 1 | 3 | 2008 | 3 | 0 | 3 | 2009 | 2 | 1 | 3 | 2010 | 2 | 1 | 3 | 2011 | 3 | 1 | 4 | 2012 | 0 | 5 | 5 | 2013 | 6 | 2 | 8 | 2014 | 4 | 1 | 5 | 2015 | 1 | 0 | 1 | 2016 | 8 | 1 | 9 | 2017 | 4 | 4 | 8 | 2018 | 8 | 2 | 10 | 2019 | 8 | 4 | 12 | 2020 | 6 | 5 | 11 | 2021 | 8 | 3 | 11 | 2022 | 4 | 6 | 10 | 2023 | 4 | 8 | 12 |
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Below are the most recent publications written about "Complement System Proteins" by people in Profiles.
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Li Y, Moein Moghimi S, Simberg D. Complement-dependent uptake of nanoparticles by blood phagocytes: brief overview and perspective. Curr Opin Biotechnol. 2024 02; 85:103044.
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Haroon HB, Dhillon E, Farhangrazi ZS, Trohopoulos PN, Simberg D, Moghimi SM. Activation of the complement system by nanoparticles and strategies for complement inhibition. Eur J Pharm Biopharm. 2023 Dec; 193:227-240.
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Petr V, Thurman JM. The role of complement in kidney disease. Nat Rev Nephrol. 2023 12; 19(12):771-787.
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Scheinman RI, Banda NK. Does complement play a role in pathogenic ACPA? Arthritis Rheumatol. 2023 11; 75(11):2062-2063.
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Zhang H, Gerasimovskaya E, McCarthy MK, May NA, Prasad RR, Riddle S, McKeon BA, Kumar S, Li M, Hu CJ, Frid MG, Morrison TE, Stenmark KR. Local Complement Contributes to Pathogenic Activation of Lung Endothelial Cells in SARS-CoV-2 Infection. Am J Respir Cell Mol Biol. 2023 08; 69(2):210-219.
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Holers VM. Complement therapeutics are coming of age in rheumatology. Nat Rev Rheumatol. 2023 08; 19(8):470-485.
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Yandamuri SS, Filipek B, Obaid AH, Lele N, Thurman JM, Makhani N, Nowak RJ, Guo Y, Lucchinetti CF, Flanagan EP, Longbrake EE, O'Connor KC. MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicity. JCI Insight. 2023 06 08; 8(11).
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Zhou W, Graner M, Paucek P, Beseler C, Boisen M, Bubak A, Asturias F, George W, Graner A, Ormond D, Vollmer T, Alvarez E, Yu X. Multiple sclerosis plasma IgG aggregates induce complement-dependent neuronal apoptosis. Cell Death Dis. 2023 04 08; 14(4):254.
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Moghimi SM, Haroon HB, Yaghmur A, Hunter AC, Papini E, Farhangrazi ZS, Simberg D, Trohopoulos PN. Perspectives on complement and phagocytic cell responses to nanoparticles: From fundamentals to adverse reactions. J Control Release. 2023 04; 356:115-129.
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Giang J, van Doorn MBA, Diercks GFH, de Cordoba SR, van den Bosch TPP, Schreurs MWJ, Poppelaars F, Damman J. Successful pharmacological intervention at different levels of the complement system in an in vitro complement fixation model for bullous pemphigoid. Exp Dermatol. 2023 05; 32(5):632-640.
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