Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Jay Hesselberth

Concepts (398)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Saccharomyces cerevisiae
17
2025
557
2.690
Why?
Sequence Analysis, RNA
10
2025
452
2.140
Why?
Saccharomyces cerevisiae Proteins
9
2023
405
1.850
Why?
Single-Cell Analysis
10
2025
313
1.730
Why?
RNA Splicing
4
2019
269
1.490
Why?
DNA Repair
4
2020
231
1.280
Why?
RNA, Messenger
16
2025
2833
1.260
Why?
RNA
7
2023
921
1.210
Why?
RNA, Transfer
3
2025
138
1.200
Why?
Basic-Leucine Zipper Transcription Factors
2
2019
41
1.170
Why?
RNA Stability
5
2025
117
1.030
Why?
Aminoacylation
1
2025
14
0.960
Why?
High-Throughput Nucleotide Sequencing
9
2020
539
0.950
Why?
Repressor Proteins
2
2019
427
0.910
Why?
Unfolded Protein Response
4
2019
59
0.890
Why?
Sequence Analysis, DNA
5
2020
812
0.860
Why?
Introns
5
2017
258
0.710
Why?
RNA Ligase (ATP)
3
2017
6
0.710
Why?
Gene Expression Regulation, Fungal
3
2019
72
0.690
Why?
Endoribonucleases
3
2015
81
0.660
Why?
RNA Cleavage
2
2015
10
0.580
Why?
Phosphorylation
1
2023
1759
0.580
Why?
Phosphotransferases (Alcohol Group Acceptor)
1
2017
45
0.560
Why?
DNA
3
2021
1459
0.560
Why?
Protein Interaction Mapping
3
2010
109
0.550
Why?
Cell Cycle Proteins
2
2017
617
0.520
Why?
RNA Precursors
4
2014
154
0.520
Why?
Gene Expression
3
2020
1502
0.500
Why?
Base Sequence
11
2015
2181
0.480
Why?
Transcriptome
4
2022
971
0.470
Why?
RNA Nucleotidyltransferases
2
2014
21
0.460
Why?
Pyrimidine Dimers
1
2014
6
0.450
Why?
DNA Repair Enzymes
1
2014
28
0.440
Why?
RNA, Catalytic
5
2004
187
0.430
Why?
MicroRNAs
4
2016
692
0.360
Why?
Alternative Splicing
1
2013
229
0.360
Why?
RNA, Long Noncoding
1
2013
181
0.350
Why?
Lymph Nodes
3
2024
491
0.340
Why?
Saccharomyces
1
2010
8
0.340
Why?
Chimera
1
2010
58
0.330
Why?
Molecular Sequence Data
12
2015
2900
0.320
Why?
B-Lymphocytes
2
2025
847
0.310
Why?
DNA Footprinting
1
2009
33
0.310
Why?
Peptides
2
2025
985
0.310
Why?
Spliceosomes
3
2014
48
0.310
Why?
Nucleosomes
1
2010
155
0.290
Why?
CD8-Positive T-Lymphocytes
2
2025
900
0.280
Why?
Biosensing Techniques
4
2006
129
0.280
Why?
Binding Sites
6
2018
1303
0.270
Why?
Uracil
2
2018
31
0.270
Why?
DNA Replication
3
2017
238
0.270
Why?
Software
4
2021
665
0.270
Why?
Models, Genetic
4
2010
600
0.250
Why?
Oligonucleotides
3
2004
148
0.250
Why?
Protein Array Analysis
1
2006
57
0.250
Why?
Hibernation
2
2018
75
0.250
Why?
Ligases
2
2003
32
0.250
Why?
Polyadenylation
2
2017
42
0.240
Why?
Computational Biology
4
2021
644
0.240
Why?
Chikungunya Fever
2
2024
79
0.240
Why?
Immunologic Memory
2
2025
353
0.240
Why?
Blotting, Northern
1
2025
201
0.240
Why?
Promoter Regions, Genetic
1
2010
1250
0.240
Why?
Nonsense Mediated mRNA Decay
1
2025
16
0.230
Why?
Codon, Nonsense
1
2025
44
0.230
Why?
Genome, Fungal
3
2017
40
0.230
Why?
Amino Acid Sequence
4
2025
2139
0.230
Why?
Cell Differentiation
4
2023
1991
0.230
Why?
Nucleotides
1
2025
125
0.230
Why?
Exons
2
2017
355
0.220
Why?
Endothelial Cells
5
2024
785
0.220
Why?
Transcription Factors
3
2023
1719
0.210
Why?
Protein Binding
7
2020
2224
0.210
Why?
RNA, Small Nuclear
3
2014
37
0.210
Why?
Gene Library
3
2019
118
0.210
Why?
Mutation
7
2020
3958
0.210
Why?
Genetic Techniques
3
2015
64
0.200
Why?
Gene Expression Profiling
6
2021
1774
0.200
Why?
RNA, Viral
3
2021
656
0.200
Why?
Yeasts
2
2018
53
0.200
Why?
Signal Transduction
5
2020
5079
0.200
Why?
Viral Proteins
1
2025
342
0.200
Why?
Chikungunya virus
1
2024
80
0.200
Why?
Animals
20
2025
36940
0.190
Why?
Stress, Physiological
1
2025
443
0.190
Why?
Escherichia coli
2
2018
815
0.190
Why?
Gain of Function Mutation
1
2021
36
0.180
Why?
Haploinsufficiency
1
2021
56
0.180
Why?
Mice
11
2025
17787
0.180
Why?
Alphavirus Infections
1
2021
44
0.180
Why?
Replication Origin
2
2017
19
0.180
Why?
Immunoprecipitation
3
2016
155
0.180
Why?
Lymphocyte Activation
1
2025
1142
0.170
Why?
Gene Editing
1
2021
80
0.170
Why?
Murine hepatitis virus
1
2020
16
0.170
Why?
Viremia
1
2021
138
0.170
Why?
RNA, Small Cytoplasmic
1
2020
7
0.170
Why?
Mice, Inbred C57BL
8
2025
5757
0.170
Why?
Ricin
1
2000
8
0.170
Why?
Receptors, Immunologic
1
2021
216
0.170
Why?
Sensitivity and Specificity
4
2016
1946
0.160
Why?
Sequence Alignment
2
2014
343
0.160
Why?
Machine Learning
1
2025
493
0.160
Why?
Viral Nonstructural Proteins
1
2020
65
0.160
Why?
rac GTP-Binding Proteins
1
2020
32
0.160
Why?
Cerebellar Neoplasms
1
2022
152
0.160
Why?
Mouse Embryonic Stem Cells
1
2020
30
0.160
Why?
Cluster Analysis
2
2019
499
0.160
Why?
Neoplastic Cells, Circulating
1
2020
80
0.160
Why?
Medulloblastoma
1
2022
193
0.160
Why?
Extracellular Fluid
1
2019
31
0.160
Why?
Genetic Therapy
1
2021
297
0.160
Why?
rho GTP-Binding Proteins
1
2020
60
0.160
Why?
Cell Line
4
2020
2847
0.160
Why?
Integrins
1
2020
95
0.160
Why?
Antigens
1
2021
357
0.150
Why?
Myeloid-Lymphoid Leukemia Protein
1
2020
70
0.150
Why?
DNA, Single-Stranded
1
2000
118
0.150
Why?
DNA, Complementary
1
2019
272
0.150
Why?
Hematopoiesis
1
2020
192
0.150
Why?
RNA Editing
1
2018
24
0.150
Why?
Exoribonucleases
1
2019
49
0.150
Why?
Thymocytes
1
2018
36
0.150
Why?
Ependymoma
1
2020
165
0.150
Why?
Tunicamycin
1
2017
12
0.140
Why?
Bleomycin
1
2019
248
0.140
Why?
Alveolar Epithelial Cells
1
2019
114
0.140
Why?
Chromatids
1
2017
9
0.140
Why?
Substrate Specificity
2
2017
372
0.140
Why?
Lymphocytes
1
2020
397
0.140
Why?
Histone-Lysine N-Methyltransferase
1
2020
136
0.140
Why?
Cells, Cultured
7
2021
4193
0.140
Why?
Natural Killer T-Cells
1
2018
67
0.140
Why?
Azacitidine
1
2018
140
0.140
Why?
Precision Medicine
1
2021
429
0.140
Why?
Epilepsy
1
2021
333
0.140
Why?
Meiosis
1
2017
82
0.140
Why?
Superoxide Dismutase
1
2019
346
0.130
Why?
Autoantibodies
1
2025
1496
0.130
Why?
Hepatitis C, Chronic
1
2019
164
0.130
Why?
Regeneration
1
2019
197
0.130
Why?
Ligands
4
2006
664
0.130
Why?
RNA-Binding Proteins
2
2016
422
0.130
Why?
Mutagenesis
1
2017
179
0.130
Why?
Bridged Bicyclo Compounds, Heterocyclic
1
2018
227
0.130
Why?
Oligonucleotide Array Sequence Analysis
3
2007
767
0.130
Why?
DNA, Mitochondrial
2
2015
200
0.130
Why?
Humans
28
2025
137585
0.130
Why?
Mammals
1
2018
283
0.130
Why?
Recombination, Genetic
1
2017
204
0.130
Why?
Host-Pathogen Interactions
2
2021
364
0.130
Why?
Macrophages, Alveolar
1
2019
391
0.130
Why?
Virus Integration
1
2016
71
0.130
Why?
Membrane Glycoproteins
1
2019
500
0.130
Why?
Transforming Growth Factor beta
1
2019
480
0.130
Why?
Lung Injury
1
2019
219
0.120
Why?
Leukocytes, Mononuclear
1
2019
558
0.120
Why?
Macrophages
3
2021
1547
0.120
Why?
RNA, Fungal
2
2014
72
0.120
Why?
Phenotype
3
2020
3196
0.120
Why?
T-Lymphocyte Subsets
1
2018
417
0.120
Why?
Nucleic Acid Conformation
3
2013
728
0.120
Why?
Non-alcoholic Fatty Liver Disease
1
2019
279
0.120
Why?
Carcinogenesis
1
2017
217
0.120
Why?
Gene Expression Regulation
2
2018
2607
0.120
Why?
Artifacts
1
2016
129
0.120
Why?
Extracellular Matrix
1
2019
528
0.120
Why?
Amino Acyl-tRNA Synthetases
1
2015
30
0.120
Why?
Temperature
1
2018
679
0.120
Why?
Mitochondrial Proteins
1
2017
257
0.120
Why?
3-Hydroxyacyl CoA Dehydrogenases
1
2015
9
0.120
Why?
Acetyl-CoA C-Acetyltransferase
1
2015
9
0.120
Why?
DNA Damage
1
2018
420
0.120
Why?
Ribonucleotides
1
2015
26
0.120
Why?
Ultraviolet Rays
1
2018
396
0.120
Why?
Lipid Metabolism, Inborn Errors
1
2015
19
0.110
Why?
Brain
2
2018
2668
0.110
Why?
Sulfonamides
1
2018
513
0.110
Why?
Thermogenesis
1
2015
44
0.110
Why?
Genomics
1
2020
795
0.110
Why?
Cytoskeletal Proteins
1
2015
158
0.110
Why?
Catalysis
2
2014
307
0.110
Why?
Adipose Tissue, Brown
1
2015
53
0.110
Why?
Protein Biosynthesis
3
2002
433
0.110
Why?
Neoplastic Stem Cells
1
2018
399
0.110
Why?
DNA, Viral
1
2016
364
0.110
Why?
Ribonuclease, Pancreatic
1
2014
12
0.110
Why?
Receptors, Antigen, T-Cell
1
2018
718
0.110
Why?
Influenza A virus
1
2014
107
0.110
Why?
RNA, Small Nucleolar
1
2013
9
0.100
Why?
Apoptosis
2
2019
2553
0.100
Why?
Breast Neoplasms
2
2017
2253
0.100
Why?
Drosophila Proteins
1
2015
204
0.100
Why?
Drosophila melanogaster
1
2015
233
0.100
Why?
Ribonucleoprotein, U5 Small Nuclear
1
2013
11
0.100
Why?
Escherichia coli Proteins
1
2015
200
0.100
Why?
Nucleic Acids
2
2006
71
0.100
Why?
Ribonucleoprotein, U4-U6 Small Nuclear
1
2013
11
0.100
Why?
Liver
2
2019
1943
0.100
Why?
Eukaryota
1
2013
57
0.100
Why?
Energy Metabolism
2
2018
922
0.100
Why?
Bone Marrow Cells
1
2014
316
0.100
Why?
Receptors, Cytoplasmic and Nuclear
1
2014
220
0.100
Why?
Caenorhabditis elegans Proteins
1
2014
199
0.090
Why?
Mitochondria
2
2017
948
0.090
Why?
Leukemia, Myeloid, Acute
1
2018
630
0.090
Why?
Genome, Human
1
2014
425
0.090
Why?
Nerve Tissue Proteins
1
2015
596
0.090
Why?
Evolution, Molecular
2
2018
493
0.090
Why?
Adipose Tissue
1
2015
635
0.090
Why?
Mice, Transgenic
3
2021
2167
0.090
Why?
Protein Footprinting
1
2010
11
0.080
Why?
AT Rich Sequence
1
2010
4
0.080
Why?
HIV-1
1
2016
864
0.080
Why?
DNA-Binding Proteins
1
2017
1502
0.080
Why?
Transcription, Genetic
2
2015
1457
0.080
Why?
Protein Structure, Tertiary
3
2006
861
0.080
Why?
DNA Methylation
1
2014
643
0.080
Why?
Inflammation
1
2019
2837
0.070
Why?
Diabetes Mellitus, Type 1
1
2025
3715
0.070
Why?
Nucleotide Motifs
2
2020
35
0.070
Why?
DNA Primers
2
2016
515
0.070
Why?
Amino Acids
1
2010
497
0.060
Why?
Neurons
1
2015
1590
0.060
Why?
Two-Hybrid System Techniques
1
2005
59
0.060
Why?
Plasmodium falciparum
1
2005
30
0.060
Why?
Malaria, Falciparum
1
2005
27
0.060
Why?
Amino Acid Motifs
1
2006
225
0.060
Why?
Peptide Chain Termination, Translational
1
2025
9
0.060
Why?
Codon, Terminator
1
2025
25
0.060
Why?
Sciuridae
2
2018
147
0.060
Why?
Protozoan Proteins
1
2005
82
0.060
Why?
Forkhead Box Protein O1
1
2025
33
0.060
Why?
Toll-Like Receptors
1
2006
185
0.060
Why?
Metabolomics
1
2010
678
0.060
Why?
Algorithms
2
2010
1704
0.060
Why?
Receptors, Antigen, B-Cell
1
2025
130
0.060
Why?
Models, Biological
2
2015
1783
0.050
Why?
Mutation, Missense
1
2006
341
0.050
Why?
Databases, Nucleic Acid
1
2004
34
0.050
Why?
Reverse Transcription
2
2016
20
0.050
Why?
Gene Expression Regulation, Neoplastic
2
2022
1396
0.050
Why?
Genetic Engineering
1
2004
93
0.050
Why?
Thiamine Pyrophosphate
1
2002
3
0.050
Why?
Adaptor Proteins, Signal Transducing
1
2006
430
0.050
Why?
Cobamides
1
2002
20
0.050
Why?
Feedback, Physiological
1
2002
77
0.050
Why?
Listeria monocytogenes
1
2023
126
0.050
Why?
Phylogeny
1
2006
904
0.050
Why?
Biological Evolution
1
2006
474
0.050
Why?
Alphavirus
1
2021
21
0.050
Why?
Kupffer Cells
1
2021
50
0.050
Why?
Immunization
1
2024
411
0.040
Why?
Phosphorothioate Oligonucleotides
1
2021
11
0.040
Why?
Caveolae
1
2021
18
0.040
Why?
Peptide Fragments
2
2021
706
0.040
Why?
Oligonucleotides, Antisense
1
2021
112
0.040
Why?
Mice, Mutant Strains
1
2021
298
0.040
Why?
Metadata
1
2021
14
0.040
Why?
Ovalbumin
1
2021
183
0.040
Why?
Female
7
2025
73304
0.040
Why?
Hedgehog Proteins
1
2022
195
0.040
Why?
Tissue Distribution
1
2021
332
0.040
Why?
Epithelial Cells
2
2014
1096
0.040
Why?
Embryoid Bodies
1
2020
8
0.040
Why?
Meta-Analysis as Topic
1
2021
186
0.040
Why?
Reverse Transcriptase Polymerase Chain Reaction
2
2016
976
0.040
Why?
Endocytosis
1
2021
172
0.040
Why?
Colony-Forming Units Assay
1
2020
91
0.040
Why?
Antigen Presentation
1
2021
218
0.040
Why?
Molecular Conformation
1
2000
145
0.040
Why?
Male
6
2025
67762
0.040
Why?
Tricarboxylic Acids
1
2018
10
0.040
Why?
beta-Defensins
1
1998
21
0.040
Why?
Ketoglutaric Acids
1
2018
16
0.040
Why?
Antibodies
1
2001
410
0.040
Why?
Protein Structure, Secondary
1
2000
374
0.040
Why?
Mesoderm
1
2020
144
0.040
Why?
Antibiotics, Antineoplastic
1
2019
127
0.040
Why?
Lipoproteins, LDL
1
2019
116
0.040
Why?
Electron Transport Complex II
1
2018
26
0.040
Why?
Islets of Langerhans
1
2025
803
0.040
Why?
Succinate Dehydrogenase
1
2018
50
0.040
Why?
Early Growth Response Protein 2
1
2018
10
0.040
Why?
Lymphatic Vessels
1
2019
64
0.040
Why?
Torpor
1
2018
14
0.040
Why?
Primary Cell Culture
1
2019
171
0.040
Why?
Cell Adhesion
1
2020
466
0.040
Why?
In Vitro Techniques
1
2000
1092
0.040
Why?
NFATC Transcription Factors
1
2018
95
0.040
Why?
Loss of Function Mutation
1
2017
46
0.030
Why?
Dendritic Cells
1
2021
483
0.030
Why?
Oxidative Phosphorylation
1
2018
193
0.030
Why?
Tumor Microenvironment
1
2022
674
0.030
Why?
G1 Phase
1
2017
71
0.030
Why?
S Phase
1
2017
77
0.030
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
233
0.030
Why?
MCF-7 Cells
1
2017
124
0.030
Why?
3' Untranslated Regions
1
2017
145
0.030
Why?
Fibrosis
1
2019
552
0.030
Why?
Aged, 80 and over
2
2019
7635
0.030
Why?
Hematopoietic Stem Cells
1
2020
406
0.030
Why?
Proteins
1
2002
1009
0.030
Why?
Disease-Free Survival
1
2017
686
0.030
Why?
Crosses, Genetic
1
2015
137
0.030
Why?
Mice, Inbred BALB C
1
2018
1272
0.030
Why?
Lipopolysaccharides
1
2019
886
0.030
Why?
Uracil-DNA Glycosidase
1
2015
1
0.030
Why?
GC Rich Sequence
1
2015
4
0.030
Why?
Gas Chromatography-Mass Spectrometry
1
2015
132
0.030
Why?
Dyskinesias
1
2015
19
0.030
Why?
Cell Respiration
1
2015
103
0.030
Why?
DNA, Fungal
1
2015
80
0.030
Why?
Molecular Sequence Annotation
1
2015
99
0.030
Why?
Electron Transport
1
2015
115
0.030
Why?
Body Size
1
2015
108
0.030
Why?
Hydrolysis
1
2014
177
0.030
Why?
Reactive Oxygen Species
1
2017
622
0.030
Why?
Larva
1
2015
226
0.030
Why?
Serrate-Jagged Proteins
1
2014
27
0.030
Why?
Jagged-1 Protein
1
2014
23
0.030
Why?
Argonaute Proteins
1
2014
27
0.030
Why?
Receptors, Steroid
1
2014
50
0.030
Why?
Wnt-5a Protein
1
2014
23
0.030
Why?
Arousal
1
2015
155
0.030
Why?
RNA Processing, Post-Transcriptional
1
2015
92
0.030
Why?
Matrix Metalloproteinase 2
1
2014
56
0.030
Why?
Body Temperature
1
2015
222
0.030
Why?
Gene Knockdown Techniques
1
2014
327
0.030
Why?
Muscles
1
2015
326
0.030
Why?
Stromal Cells
1
2014
112
0.030
Why?
Chromatin
1
2017
519
0.030
Why?
Cellular Microenvironment
1
2014
84
0.030
Why?
Poliovirus
1
2014
85
0.030
Why?
RNA, Ribosomal
1
2014
168
0.030
Why?
Neoplasm Grading
1
2014
307
0.030
Why?
Ribonucleoproteins, Small Nuclear
1
2013
24
0.030
Why?
Wnt Proteins
1
2014
133
0.030
Why?
Chronic Disease
1
2019
1793
0.020
Why?
Child
2
2025
21935
0.020
Why?
Calcium-Binding Proteins
1
2014
218
0.020
Why?
Base Pairing
2
2004
64
0.020
Why?
RNA Interference
1
2014
469
0.020
Why?
Intercellular Signaling Peptides and Proteins
1
2014
382
0.020
Why?
HeLa Cells
1
2014
636
0.020
Why?
Hepacivirus
1
2014
261
0.020
Why?
Gene Regulatory Networks
1
2014
305
0.020
Why?
Virus Replication
1
2014
483
0.020
Why?
Polymorphism, Single Nucleotide
1
2019
2189
0.020
Why?
Down-Regulation
1
2014
657
0.020
Why?
Receptors, Estrogen
1
2014
436
0.020
Why?
Estrogens
1
2014
367
0.020
Why?
Caenorhabditis elegans
1
2014
306
0.020
Why?
Vascular Endothelial Growth Factor A
1
2014
545
0.020
Why?
Proto-Oncogene Proteins
1
2014
648
0.020
Why?
Gene Expression Regulation, Developmental
1
2015
860
0.020
Why?
Transcription Initiation Site
1
2010
43
0.020
Why?
Carrier Proteins
1
2014
771
0.020
Why?
Rats
1
2019
5647
0.020
Why?
Time Factors
1
2021
6828
0.020
Why?
Brain Chemistry
1
2010
117
0.020
Why?
Myocardium
1
2015
1002
0.020
Why?
Adult
2
2025
37929
0.020
Why?
Aged
2
2019
23961
0.020
Why?
Organophosphates
1
2010
134
0.020
Why?
Arabidopsis
1
2010
95
0.020
Why?
Cloning, Molecular
1
2010
534
0.020
Why?
Gene Deletion
1
2010
391
0.020
Why?
Disease Models, Animal
1
2019
4295
0.020
Why?
Biomarkers
1
2020
4149
0.020
Why?
Bayes Theorem
1
2010
405
0.020
Why?
Genome
1
2010
300
0.020
Why?
Membrane Proteins
1
2014
1164
0.020
Why?
Lung
1
2019
4060
0.020
Why?
Cell Line, Tumor
1
2014
3412
0.020
Why?
Chaperonin 60
1
2006
14
0.020
Why?
Severity of Illness Index
1
2014
2828
0.020
Why?
Aptamers, Nucleotide
1
2006
83
0.020
Why?
Adolescent
1
2025
21513
0.010
Why?
Prognosis
1
2014
4030
0.010
Why?
Myeloid Differentiation Factor 88
1
2006
99
0.010
Why?
Genetic Variation
1
2010
991
0.010
Why?
Virulence Factors
1
2005
167
0.010
Why?
Infant, Newborn
1
2015
6079
0.010
Why?
Biotinylation
1
2002
32
0.010
Why?
Ribonucleoprotein, U1 Small Nuclear
1
2002
13
0.010
Why?
Automation
1
2002
95
0.010
Why?
HIV Infections
1
2016
2836
0.010
Why?
Directed Molecular Evolution
1
2001
21
0.010
Why?
Infant
1
2015
9465
0.010
Why?
Defensins
1
1998
4
0.010
Why?
Internet
1
2004
655
0.010
Why?
Reproducibility of Results
1
2007
3284
0.010
Why?
In Situ Hybridization
1
1998
316
0.010
Why?
Respiratory System
1
1998
157
0.010
Why?
Middle Aged
1
2019
33479
0.010
Why?
Models, Molecular
1
2001
1570
0.010
Why?
Interleukin-1
1
1998
965
0.010
Why?
Hesselberth's Networks
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