Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Jay Hesselberth

Concepts (398)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Saccharomyces cerevisiae
17
2025
552
2.670
Why?
Sequence Analysis, RNA
10
2025
452
2.120
Why?
Saccharomyces cerevisiae Proteins
9
2023
401
1.840
Why?
Single-Cell Analysis
10
2025
324
1.700
Why?
RNA Splicing
4
2019
270
1.470
Why?
DNA Repair
4
2020
231
1.260
Why?
RNA, Messenger
16
2025
2799
1.250
Why?
RNA
7
2023
926
1.200
Why?
RNA, Transfer
3
2025
139
1.180
Why?
Basic-Leucine Zipper Transcription Factors
2
2019
41
1.150
Why?
RNA Stability
5
2025
112
1.020
Why?
Aminoacylation
1
2025
14
0.950
Why?
High-Throughput Nucleotide Sequencing
9
2020
541
0.940
Why?
Repressor Proteins
2
2019
423
0.910
Why?
Unfolded Protein Response
4
2019
59
0.870
Why?
Sequence Analysis, DNA
5
2020
828
0.850
Why?
Introns
5
2017
256
0.700
Why?
RNA Ligase (ATP)
3
2017
6
0.700
Why?
Gene Expression Regulation, Fungal
3
2019
72
0.680
Why?
Endoribonucleases
3
2015
78
0.660
Why?
Phosphorylation
1
2023
1760
0.580
Why?
RNA Cleavage
2
2015
10
0.580
Why?
DNA
3
2021
1448
0.560
Why?
Phosphotransferases (Alcohol Group Acceptor)
1
2017
45
0.560
Why?
Protein Interaction Mapping
3
2010
106
0.550
Why?
Cell Cycle Proteins
2
2017
614
0.520
Why?
RNA Precursors
4
2014
154
0.510
Why?
Gene Expression
3
2020
1487
0.500
Why?
Base Sequence
11
2015
2180
0.470
Why?
Transcriptome
4
2022
969
0.470
Why?
RNA Nucleotidyltransferases
2
2014
21
0.460
Why?
Pyrimidine Dimers
1
2014
6
0.440
Why?
DNA Repair Enzymes
1
2014
28
0.440
Why?
RNA, Catalytic
5
2004
188
0.430
Why?
MicroRNAs
4
2016
678
0.360
Why?
Alternative Splicing
1
2013
226
0.350
Why?
RNA, Long Noncoding
1
2013
172
0.350
Why?
Lymph Nodes
3
2024
493
0.330
Why?
Saccharomyces
1
2010
7
0.330
Why?
Chimera
1
2010
60
0.330
Why?
Molecular Sequence Data
12
2015
2925
0.320
Why?
B-Lymphocytes
2
2025
849
0.310
Why?
Peptides
2
2025
980
0.310
Why?
DNA Footprinting
1
2009
33
0.310
Why?
Spliceosomes
3
2014
48
0.300
Why?
Nucleosomes
1
2010
155
0.280
Why?
CD8-Positive T-Lymphocytes
2
2025
912
0.280
Why?
Biosensing Techniques
4
2006
134
0.280
Why?
Binding Sites
6
2018
1317
0.270
Why?
Uracil
2
2018
31
0.270
Why?
DNA Replication
3
2017
239
0.270
Why?
Software
4
2021
665
0.270
Why?
Models, Genetic
4
2010
589
0.250
Why?
Oligonucleotides
3
2004
147
0.240
Why?
Protein Array Analysis
1
2006
56
0.240
Why?
Hibernation
2
2018
75
0.240
Why?
Ligases
2
2003
32
0.240
Why?
Polyadenylation
2
2017
42
0.240
Why?
Computational Biology
4
2021
649
0.240
Why?
Chikungunya Fever
2
2024
79
0.240
Why?
Immunologic Memory
2
2025
358
0.240
Why?
Promoter Regions, Genetic
1
2010
1237
0.240
Why?
Blotting, Northern
1
2025
201
0.240
Why?
Nonsense Mediated mRNA Decay
1
2025
16
0.230
Why?
Codon, Nonsense
1
2025
43
0.230
Why?
Amino Acid Sequence
4
2025
2159
0.230
Why?
Genome, Fungal
3
2017
41
0.230
Why?
Cell Differentiation
4
2023
1999
0.220
Why?
Nucleotides
1
2025
126
0.220
Why?
Exons
2
2017
353
0.220
Why?
Endothelial Cells
5
2024
786
0.220
Why?
Transcription Factors
3
2023
1709
0.210
Why?
Protein Binding
7
2020
2232
0.210
Why?
RNA, Small Nuclear
3
2014
37
0.210
Why?
Gene Library
3
2019
119
0.210
Why?
Mutation
7
2020
3994
0.200
Why?
Genetic Techniques
3
2015
67
0.200
Why?
Gene Expression Profiling
6
2021
1755
0.200
Why?
Yeasts
2
2018
53
0.200
Why?
Signal Transduction
5
2020
5068
0.200
Why?
RNA, Viral
3
2021
688
0.200
Why?
Chikungunya virus
1
2024
80
0.190
Why?
Viral Proteins
1
2025
361
0.190
Why?
Animals
20
2025
37151
0.190
Why?
Stress, Physiological
1
2025
452
0.180
Why?
Escherichia coli
2
2018
826
0.180
Why?
Gain of Function Mutation
1
2021
35
0.180
Why?
Haploinsufficiency
1
2021
56
0.180
Why?
Mice
11
2025
17769
0.180
Why?
Alphavirus Infections
1
2021
45
0.180
Why?
Replication Origin
2
2017
21
0.170
Why?
Immunoprecipitation
3
2016
152
0.170
Why?
Lymphocyte Activation
1
2025
1146
0.170
Why?
Gene Editing
1
2021
84
0.170
Why?
Murine hepatitis virus
1
2020
16
0.170
Why?
Viremia
1
2021
152
0.170
Why?
RNA, Small Cytoplasmic
1
2020
7
0.170
Why?
Mice, Inbred C57BL
8
2025
5769
0.170
Why?
Ricin
1
2000
8
0.160
Why?
Receptors, Immunologic
1
2021
215
0.160
Why?
Sensitivity and Specificity
4
2016
1946
0.160
Why?
Viral Nonstructural Proteins
1
2020
67
0.160
Why?
Sequence Alignment
2
2014
360
0.160
Why?
Cerebellar Neoplasms
1
2022
153
0.160
Why?
rac GTP-Binding Proteins
1
2020
36
0.160
Why?
Machine Learning
1
2025
516
0.160
Why?
Mouse Embryonic Stem Cells
1
2020
30
0.160
Why?
Neoplastic Cells, Circulating
1
2020
79
0.160
Why?
Cluster Analysis
2
2019
515
0.160
Why?
Medulloblastoma
1
2022
193
0.160
Why?
Extracellular Fluid
1
2019
31
0.160
Why?
rho GTP-Binding Proteins
1
2020
60
0.150
Why?
Genetic Therapy
1
2021
310
0.150
Why?
Cell Line
4
2020
2865
0.150
Why?
Integrins
1
2020
95
0.150
Why?
Antigens
1
2021
356
0.150
Why?
Myeloid-Lymphoid Leukemia Protein
1
2020
70
0.150
Why?
DNA, Single-Stranded
1
2000
120
0.150
Why?
Hematopoiesis
1
2020
193
0.150
Why?
DNA, Complementary
1
2019
275
0.150
Why?
RNA Editing
1
2018
24
0.150
Why?
Exoribonucleases
1
2019
48
0.140
Why?
Thymocytes
1
2018
35
0.140
Why?
Ependymoma
1
2020
163
0.140
Why?
Tunicamycin
1
2017
13
0.140
Why?
Bleomycin
1
2019
248
0.140
Why?
Alveolar Epithelial Cells
1
2019
114
0.140
Why?
Chromatids
1
2017
9
0.140
Why?
Lymphocytes
1
2020
392
0.140
Why?
Histone-Lysine N-Methyltransferase
1
2020
134
0.140
Why?
Substrate Specificity
2
2017
385
0.140
Why?
Cells, Cultured
7
2021
4160
0.140
Why?
Natural Killer T-Cells
1
2018
67
0.140
Why?
Azacitidine
1
2018
140
0.140
Why?
Precision Medicine
1
2021
420
0.130
Why?
Epilepsy
1
2021
335
0.130
Why?
Meiosis
1
2017
84
0.130
Why?
Autoantibodies
1
2025
1454
0.130
Why?
Superoxide Dismutase
1
2019
352
0.130
Why?
Hepatitis C, Chronic
1
2019
165
0.130
Why?
Regeneration
1
2019
198
0.130
Why?
Ligands
4
2006
666
0.130
Why?
RNA-Binding Proteins
2
2016
427
0.130
Why?
Mutagenesis
1
2017
182
0.130
Why?
Bridged Bicyclo Compounds, Heterocyclic
1
2018
229
0.130
Why?
Oligonucleotide Array Sequence Analysis
3
2007
758
0.130
Why?
DNA, Mitochondrial
2
2015
208
0.130
Why?
Humans
28
2025
138102
0.130
Why?
Mammals
1
2018
287
0.130
Why?
Recombination, Genetic
1
2017
208
0.130
Why?
Virus Integration
1
2016
69
0.120
Why?
Host-Pathogen Interactions
2
2021
376
0.120
Why?
Macrophages, Alveolar
1
2019
396
0.120
Why?
Membrane Glycoproteins
1
2019
501
0.120
Why?
Transforming Growth Factor beta
1
2019
487
0.120
Why?
Lung Injury
1
2019
218
0.120
Why?
Macrophages
3
2021
1544
0.120
Why?
Leukocytes, Mononuclear
1
2019
568
0.120
Why?
Phenotype
3
2020
3158
0.120
Why?
RNA, Fungal
2
2014
73
0.120
Why?
Nucleic Acid Conformation
3
2013
722
0.120
Why?
T-Lymphocyte Subsets
1
2018
419
0.120
Why?
Gene Expression Regulation
2
2018
2586
0.120
Why?
Non-alcoholic Fatty Liver Disease
1
2019
279
0.120
Why?
Carcinogenesis
1
2017
216
0.120
Why?
Artifacts
1
2016
129
0.120
Why?
Extracellular Matrix
1
2019
535
0.120
Why?
Temperature
1
2018
673
0.120
Why?
Amino Acyl-tRNA Synthetases
1
2015
30
0.120
Why?
Mitochondrial Proteins
1
2017
258
0.120
Why?
3-Hydroxyacyl CoA Dehydrogenases
1
2015
9
0.110
Why?
Acetyl-CoA C-Acetyltransferase
1
2015
9
0.110
Why?
DNA Damage
1
2018
422
0.110
Why?
Ribonucleotides
1
2015
26
0.110
Why?
Ultraviolet Rays
1
2018
397
0.110
Why?
Lipid Metabolism, Inborn Errors
1
2015
18
0.110
Why?
Brain
2
2018
2725
0.110
Why?
Sulfonamides
1
2018
510
0.110
Why?
Thermogenesis
1
2015
44
0.110
Why?
Cytoskeletal Proteins
1
2015
156
0.110
Why?
Genomics
1
2020
807
0.110
Why?
Catalysis
2
2014
317
0.110
Why?
Adipose Tissue, Brown
1
2015
55
0.110
Why?
Protein Biosynthesis
3
2002
433
0.110
Why?
Neoplastic Stem Cells
1
2018
399
0.110
Why?
DNA, Viral
1
2016
369
0.110
Why?
Ribonuclease, Pancreatic
1
2014
12
0.110
Why?
Receptors, Antigen, T-Cell
1
2018
718
0.110
Why?
Influenza A virus
1
2014
111
0.110
Why?
RNA, Small Nucleolar
1
2013
8
0.100
Why?
Apoptosis
2
2019
2555
0.100
Why?
Drosophila Proteins
1
2015
202
0.100
Why?
Breast Neoplasms
2
2017
2274
0.100
Why?
Drosophila melanogaster
1
2015
234
0.100
Why?
Nucleic Acids
2
2006
70
0.100
Why?
Escherichia coli Proteins
1
2015
199
0.100
Why?
Ribonucleoprotein, U4-U6 Small Nuclear
1
2013
9
0.100
Why?
Ribonucleoprotein, U5 Small Nuclear
1
2013
11
0.100
Why?
Liver
2
2019
1874
0.100
Why?
Energy Metabolism
2
2018
923
0.100
Why?
Eukaryota
1
2013
60
0.100
Why?
Bone Marrow Cells
1
2014
323
0.100
Why?
Receptors, Cytoplasmic and Nuclear
1
2014
206
0.100
Why?
Mitochondria
2
2017
951
0.090
Why?
Caenorhabditis elegans Proteins
1
2014
213
0.090
Why?
Leukemia, Myeloid, Acute
1
2018
631
0.090
Why?
Genome, Human
1
2014
419
0.090
Why?
Nerve Tissue Proteins
1
2015
596
0.090
Why?
Evolution, Molecular
2
2018
518
0.090
Why?
Mice, Transgenic
3
2021
2166
0.090
Why?
Adipose Tissue
1
2015
645
0.090
Why?
Protein Footprinting
1
2010
11
0.080
Why?
AT Rich Sequence
1
2010
4
0.080
Why?
HIV-1
1
2016
887
0.080
Why?
DNA-Binding Proteins
1
2017
1477
0.080
Why?
Transcription, Genetic
2
2015
1455
0.080
Why?
Protein Structure, Tertiary
3
2006
864
0.080
Why?
DNA Methylation
1
2014
641
0.080
Why?
Inflammation
1
2019
2847
0.070
Why?
Diabetes Mellitus, Type 1
1
2025
3664
0.070
Why?
Nucleotide Motifs
2
2020
36
0.070
Why?
DNA Primers
2
2016
508
0.070
Why?
Amino Acids
1
2010
499
0.060
Why?
Neurons
1
2015
1593
0.060
Why?
Two-Hybrid System Techniques
1
2005
59
0.060
Why?
Plasmodium falciparum
1
2005
30
0.060
Why?
Malaria, Falciparum
1
2005
27
0.060
Why?
Amino Acid Motifs
1
2006
224
0.060
Why?
Peptide Chain Termination, Translational
1
2025
9
0.060
Why?
Codon, Terminator
1
2025
25
0.060
Why?
Sciuridae
2
2018
147
0.060
Why?
Protozoan Proteins
1
2005
83
0.060
Why?
Forkhead Box Protein O1
1
2025
33
0.060
Why?
Toll-Like Receptors
1
2006
188
0.060
Why?
Metabolomics
1
2010
686
0.060
Why?
Algorithms
2
2010
1711
0.060
Why?
Receptors, Antigen, B-Cell
1
2025
132
0.050
Why?
Models, Biological
2
2015
1784
0.050
Why?
Mutation, Missense
1
2006
340
0.050
Why?
Databases, Nucleic Acid
1
2004
38
0.050
Why?
Reverse Transcription
2
2016
20
0.050
Why?
Gene Expression Regulation, Neoplastic
2
2022
1388
0.050
Why?
Genetic Engineering
1
2004
93
0.050
Why?
Thiamine Pyrophosphate
1
2002
3
0.050
Why?
Adaptor Proteins, Signal Transducing
1
2006
430
0.050
Why?
Cobamides
1
2002
21
0.050
Why?
Feedback, Physiological
1
2002
79
0.050
Why?
Listeria monocytogenes
1
2023
121
0.050
Why?
Biological Evolution
1
2006
491
0.050
Why?
Alphavirus
1
2021
22
0.050
Why?
Kupffer Cells
1
2021
49
0.040
Why?
Phylogeny
1
2006
1009
0.040
Why?
Immunization
1
2024
405
0.040
Why?
Phosphorothioate Oligonucleotides
1
2021
11
0.040
Why?
Caveolae
1
2021
18
0.040
Why?
Peptide Fragments
2
2021
691
0.040
Why?
Oligonucleotides, Antisense
1
2021
109
0.040
Why?
Mice, Mutant Strains
1
2021
306
0.040
Why?
Metadata
1
2021
14
0.040
Why?
Ovalbumin
1
2021
190
0.040
Why?
Female
7
2025
73648
0.040
Why?
Epithelial Cells
2
2014
1100
0.040
Why?
Hedgehog Proteins
1
2022
199
0.040
Why?
Tissue Distribution
1
2021
320
0.040
Why?
Meta-Analysis as Topic
1
2021
186
0.040
Why?
Embryoid Bodies
1
2020
8
0.040
Why?
Reverse Transcriptase Polymerase Chain Reaction
2
2016
979
0.040
Why?
Endocytosis
1
2021
175
0.040
Why?
Colony-Forming Units Assay
1
2020
96
0.040
Why?
Antigen Presentation
1
2021
220
0.040
Why?
Molecular Conformation
1
2000
148
0.040
Why?
Male
6
2025
67984
0.040
Why?
Tricarboxylic Acids
1
2018
10
0.040
Why?
beta-Defensins
1
1998
23
0.040
Why?
Antibodies
1
2001
406
0.040
Why?
Protein Structure, Secondary
1
2000
373
0.040
Why?
Ketoglutaric Acids
1
2018
19
0.040
Why?
Mesoderm
1
2020
144
0.040
Why?
Antibiotics, Antineoplastic
1
2019
124
0.040
Why?
Lipoproteins, LDL
1
2019
115
0.040
Why?
Islets of Langerhans
1
2025
793
0.040
Why?
Electron Transport Complex II
1
2018
26
0.040
Why?
Succinate Dehydrogenase
1
2018
50
0.040
Why?
Early Growth Response Protein 2
1
2018
10
0.040
Why?
Lymphatic Vessels
1
2019
64
0.040
Why?
Torpor
1
2018
14
0.040
Why?
Primary Cell Culture
1
2019
172
0.040
Why?
Cell Adhesion
1
2020
465
0.040
Why?
In Vitro Techniques
1
2000
1088
0.040
Why?
NFATC Transcription Factors
1
2018
94
0.030
Why?
Tumor Microenvironment
1
2022
668
0.030
Why?
Loss of Function Mutation
1
2017
46
0.030
Why?
Oxidative Phosphorylation
1
2018
194
0.030
Why?
G1 Phase
1
2017
71
0.030
Why?
S Phase
1
2017
77
0.030
Why?
Dendritic Cells
1
2021
491
0.030
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
235
0.030
Why?
MCF-7 Cells
1
2017
123
0.030
Why?
3' Untranslated Regions
1
2017
145
0.030
Why?
Fibrosis
1
2019
544
0.030
Why?
Aged, 80 and over
2
2019
7638
0.030
Why?
Hematopoietic Stem Cells
1
2020
408
0.030
Why?
Proteins
1
2002
1011
0.030
Why?
Disease-Free Survival
1
2017
669
0.030
Why?
Mice, Inbred BALB C
1
2018
1260
0.030
Why?
Crosses, Genetic
1
2015
135
0.030
Why?
Lipopolysaccharides
1
2019
883
0.030
Why?
Uracil-DNA Glycosidase
1
2015
1
0.030
Why?
GC Rich Sequence
1
2015
4
0.030
Why?
Gas Chromatography-Mass Spectrometry
1
2015
134
0.030
Why?
Dyskinesias
1
2015
20
0.030
Why?
Cell Respiration
1
2015
103
0.030
Why?
Molecular Sequence Annotation
1
2015
99
0.030
Why?
DNA, Fungal
1
2015
79
0.030
Why?
Body Size
1
2015
107
0.030
Why?
Electron Transport
1
2015
116
0.030
Why?
Reactive Oxygen Species
1
2017
626
0.030
Why?
Hydrolysis
1
2014
194
0.030
Why?
Larva
1
2015
235
0.030
Why?
Serrate-Jagged Proteins
1
2014
27
0.030
Why?
Jagged-1 Protein
1
2014
23
0.030
Why?
Receptors, Steroid
1
2014
46
0.030
Why?
Argonaute Proteins
1
2014
27
0.030
Why?
Arousal
1
2015
155
0.030
Why?
Wnt-5a Protein
1
2014
24
0.030
Why?
RNA Processing, Post-Transcriptional
1
2015
90
0.030
Why?
Matrix Metalloproteinase 2
1
2014
56
0.030
Why?
Body Temperature
1
2015
222
0.030
Why?
Gene Knockdown Techniques
1
2014
329
0.030
Why?
Muscles
1
2015
331
0.030
Why?
Stromal Cells
1
2014
111
0.030
Why?
Chromatin
1
2017
517
0.030
Why?
Cellular Microenvironment
1
2014
84
0.030
Why?
Poliovirus
1
2014
85
0.030
Why?
RNA, Ribosomal
1
2014
168
0.030
Why?
Neoplasm Grading
1
2014
306
0.030
Why?
Ribonucleoproteins, Small Nuclear
1
2013
21
0.030
Why?
Wnt Proteins
1
2014
135
0.020
Why?
Chronic Disease
1
2019
1791
0.020
Why?
Child
2
2025
21990
0.020
Why?
Calcium-Binding Proteins
1
2014
214
0.020
Why?
Base Pairing
2
2004
64
0.020
Why?
RNA Interference
1
2014
468
0.020
Why?
Intercellular Signaling Peptides and Proteins
1
2014
384
0.020
Why?
HeLa Cells
1
2014
635
0.020
Why?
Hepacivirus
1
2014
261
0.020
Why?
Polymorphism, Single Nucleotide
1
2019
2145
0.020
Why?
Gene Regulatory Networks
1
2014
310
0.020
Why?
Virus Replication
1
2014
528
0.020
Why?
Down-Regulation
1
2014
635
0.020
Why?
Receptors, Estrogen
1
2014
435
0.020
Why?
Estrogens
1
2014
369
0.020
Why?
Vascular Endothelial Growth Factor A
1
2014
552
0.020
Why?
Caenorhabditis elegans
1
2014
329
0.020
Why?
Proto-Oncogene Proteins
1
2014
624
0.020
Why?
Carrier Proteins
1
2014
738
0.020
Why?
Transcription Initiation Site
1
2010
43
0.020
Why?
Gene Expression Regulation, Developmental
1
2015
873
0.020
Why?
Rats
1
2019
5564
0.020
Why?
Time Factors
1
2021
6845
0.020
Why?
Myocardium
1
2015
900
0.020
Why?
Brain Chemistry
1
2010
115
0.020
Why?
Adult
2
2025
38063
0.020
Why?
Aged
2
2019
23995
0.020
Why?
Arabidopsis
1
2010
98
0.020
Why?
Cloning, Molecular
1
2010
535
0.020
Why?
Gene Deletion
1
2010
391
0.020
Why?
Organophosphates
1
2010
155
0.020
Why?
Disease Models, Animal
1
2019
4309
0.020
Why?
Biomarkers
1
2020
4111
0.020
Why?
Bayes Theorem
1
2010
410
0.020
Why?
Genome
1
2010
301
0.020
Why?
Membrane Proteins
1
2014
1154
0.020
Why?
Lung
1
2019
4065
0.020
Why?
Cell Line, Tumor
1
2014
3404
0.020
Why?
Chaperonin 60
1
2006
14
0.020
Why?
Severity of Illness Index
1
2014
2838
0.020
Why?
Aptamers, Nucleotide
1
2006
83
0.010
Why?
Prognosis
1
2014
3982
0.010
Why?
Adolescent
1
2025
21637
0.010
Why?
Myeloid Differentiation Factor 88
1
2006
102
0.010
Why?
Genetic Variation
1
2010
1002
0.010
Why?
Virulence Factors
1
2005
161
0.010
Why?
Infant, Newborn
1
2015
6140
0.010
Why?
Biotinylation
1
2002
33
0.010
Why?
Ribonucleoprotein, U1 Small Nuclear
1
2002
13
0.010
Why?
Automation
1
2002
95
0.010
Why?
HIV Infections
1
2016
2945
0.010
Why?
Directed Molecular Evolution
1
2001
25
0.010
Why?
Infant
1
2015
9566
0.010
Why?
Defensins
1
1998
4
0.010
Why?
Internet
1
2004
681
0.010
Why?
Reproducibility of Results
1
2007
3301
0.010
Why?
In Situ Hybridization
1
1998
318
0.010
Why?
Respiratory System
1
1998
155
0.010
Why?
Middle Aged
1
2019
33509
0.010
Why?
Models, Molecular
1
2001
1598
0.010
Why?
Interleukin-1
1
1998
964
0.010
Why?
Hesselberth's Networks
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