 Malaria, Falciparum
"Malaria, Falciparum" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Descriptor ID |
D016778
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| MeSH Number(s) |
C03.752.530.650
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| Concept/Terms |
Malaria, Falciparum- Malaria, Falciparum
- Plasmodium falciparum Malaria
- Malaria, Plasmodium falciparum
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Below are MeSH descriptors whose meaning is more general than "Malaria, Falciparum".
Below are MeSH descriptors whose meaning is more specific than "Malaria, Falciparum".
This graph shows the total number of publications written about "Malaria, Falciparum" by people in this website by year, and whether "Malaria, Falciparum" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 1998 | 2 | 0 | 2 | | 2005 | 2 | 0 | 2 | | 2007 | 2 | 0 | 2 | | 2010 | 2 | 0 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 3 | 0 | 3 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 | | 2017 | 3 | 0 | 3 | | 2018 | 2 | 0 | 2 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2024 | 1 | 0 | 1 | | 2025 | 3 | 0 | 3 |
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Below are the most recent publications written about "Malaria, Falciparum" by people in Profiles.
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Syahada JH, Lee WJ, Jun H, Louis JM, Fitriana F, Muh F, Lu F, Ahmed MA, Na S, Chun W, Park WS, Jeon BY, Han ET, Todd J, Manjurano A, Kidima W, Mazigo E, Lee SJ, Han JH. Micro-geographic variation in antigenic diversity of PfEBA-175 region II in asymptomatic Plasmodium falciparum infections in Tanzania. Front Immunol. 2025; 16:1656267.
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Mazigo E, Jun H, Lee WJ, Louis JM, Syahada JH, Fitriana F, Muh F, Ahmed MA, Lu F, Han JH, Kwon TH, Lee SJ, Na S, Chun W, Park WS, Han ET, Kidima W, Han JH. Emergence of chloroquine-sensitive Plasmodium falciparum and rising resistance to first-line artemisinin partner drugs in Malawi. Emerg Microbes Infect. 2025 Dec; 14(1):2572679.
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Bekkering ET, Yoo R, Hailemariam S, Heide F, Ivanochko D, Jackman M, Proellochs NI, Stoter R, van Gemert GJ, Maeda A, Yuguchi T, Wanders OT, van Daalen RC, Inklaar MR, Andrade CM, Jansen PWTC, Vermeulen M, Bousema T, Takashima E, Rubinstein JL, Kooij TWA, Jore MM, Julien JP. Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity. Immunity. 2025 Nov 11; 58(11):2899-2916.e10.
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Jun H, Mazigo E, Lee WJ, Louis JM, Syahada JH, Fitriana F, Heo J, Kim Y, Kwon B, Muh F, Lu F, Ahmed MA, Lee SJ, Na S, Chun W, Park WS, Hong M, Han JH, Kwon TH, Lee SU, Han ET, Todd J, Manjurano A, Kidima W, Han JH. Estimation of PfRh5-based vaccine efficacy in asymptomatic Plasmodium falciparum patients from high-endemic areas of Tanzania using genetic and antigenicity variation screening. Front Immunol. 2024; 15:1495513.
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Nalwoga A, Sabourin KR, Miley W, Jackson C, Maktabi M, Labo N, Mugisha J, Whitby D, Rochford R, Newton R. Plasmodium falciparum Malaria Is Associated With Increased Kaposi Sarcoma-Associated Herpesvirus (KSHV) Seropositivity and Higher KSHV Antibody Breadth and Magnitude: Results of a Case-Control Study From Rural Uganda. J Infect Dis. 2024 02 14; 229(2):432-442.
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Samayoa-Reyes G, Flaherty SM, Wickham KS, Viera-Morilla S, Strauch PM, Roth A, Padrón L, Jackson CM, Meireles P, Calvo D, Roobsoong W, Kangwanrangsan N, Sattabongkot J, Reichard G, Lafuente-Monasterio MJ, Rochford R. Development of an ectopic huLiver model for Plasmodium liver stage infection. PLoS One. 2023; 18(3):e0279144.
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Sobota RS, Goron AR, Berry AA, Bailey JA, Coulibaly D, Adams M, Kone AK, Kouriba B, Doumbo OK, Sztein MB, Felgner PL, Plowe CV, Lyke KE, Thera MA, Travassos MA. Serologic and Cytokine Profiles of Children with Concurrent Cerebral Malaria and Severe Malarial Anemia Are Distinct from Other Subtypes of Severe Malaria. Am J Trop Med Hyg. 2022 08 17; 107(2):315-319.
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de Vries LE, Jansen PAM, Barcelo C, Munro J, Verhoef JMJ, Pasaje CFA, Rubiano K, Striepen J, Abla N, Berning L, Bolscher JM, Demarta-Gatsi C, Henderson RWM, Huijs T, Koolen KMJ, Tumwebaze PK, Yeo T, Aguiar ACC, Angulo-Barturen I, Churchyard A, Baum J, Fernández BC, Fuchs A, Gamo FJ, Guido RVC, Jiménez-Diaz MB, Pereira DB, Rochford R, Roesch C, Sanz LM, Trevitt G, Witkowski B, Wittlin S, Cooper RA, Rosenthal PJ, Sauerwein RW, Schalkwijk J, Hermkens PHH, Bonnert RV, Campo B, Fidock DA, Llinás M, Niles JC, Kooij TWA, Dechering KJ. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nat Commun. 2022 04 20; 13(1):2158.
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Plenderleith LJ, Liu W, Li Y, Loy DE, Mollison E, Connell J, Ayouba A, Esteban A, Peeters M, Sanz CM, Morgan DB, Wolfe ND, Ulrich M, Sachse A, Calvignac-Spencer S, Leendertz FH, Shaw GM, Hahn BH, Sharp PM. Zoonotic origin of the human malaria parasite Plasmodium malariae from African apes. Nat Commun. 2022 04 06; 13(1):1868.
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Jezewski AJ, Lin YH, Reisz JA, Culp-Hill R, Barekatain Y, Yan VC, D'Alessandro A, Muller FL, Odom John AR. Targeting Host Glycolysis as a Strategy for Antimalarial Development. Front Cell Infect Microbiol. 2021; 11:730413.
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